Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs

Mechanisms of Development

Volumn 120, Issue 5, 2003, Pages 549-560

  Bertolino, Philippe ^a,b   Radovanovic, Ivan ^c   Casse, Huguette ^b   Aguzzi, Adriano ^c   Wang, Zhao Qi ^a   Zhang, Chang Xian ^b  

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^b UNIVERSITÉ LYON 1   (France)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Chimerism analysis; Fetal liver defects; Heart hypotrophy; Men1 Embryonic lethality; Neurotube disclosure

Indexed keywords

METHIONINE; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLEEDING; CANCER INHIBITION; CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; CHIMERA; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EDEMA; EMBRYO; EMBRYO (ANATOMY); EMBRYO CELL; EMBRYO DEVELOPMENT; EPITHELIUM; FEMALE; FETUS; FIBROBLAST; GENE DISRUPTION; GESTATION PERIOD; HEART; HEMATOPOIETIC SYSTEM; HISTOPATHOLOGY; HYPOTROPHY; LETHALITY; LIVER; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL TUBE; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; SENESCENCE; WILD TYPE;

EID: 0037684907     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(03)00039-X     Document Type: Article

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