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Volumn 337, Issue 1, 2010, Pages 74-83

A critical role for sFRP proteins in maintaining caudal neural tube closure in mice via inhibition of BMP signaling

Author keywords

BMP signaling; Neural tube closure; sFRP1; sFRP2; Signal integration; Wnt signaling

Indexed keywords

BONE MORPHOGENETIC PROTEIN; SECRETED FRIZZLED RELATED PROTEIN 1; SECRETED FRIZZLED RELATED PROTEIN 2; WNT PROTEIN;

EID: 70450225232     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2009.10.015     Document Type: Article
Times cited : (35)

References (56)
  • 1
    • 33748324823 scopus 로고    scopus 로고
    • Endogenous bone morphogenetic protein antagonists regulate mammalian neural crest generation and survival
    • Anderson R.M., Stottmann R.W., Choi M., and Klingensmith J. Endogenous bone morphogenetic protein antagonists regulate mammalian neural crest generation and survival. Dev. Dyn. 235 (2006) 2507-2520
    • (2006) Dev. Dyn. , vol.235 , pp. 2507-2520
    • Anderson, R.M.1    Stottmann, R.W.2    Choi, M.3    Klingensmith, J.4
  • 2
    • 0033992481 scopus 로고    scopus 로고
    • The yin-yang of TCF/beta-catenin signaling
    • Barker N., Morin P.J., and Clevers H. The yin-yang of TCF/beta-catenin signaling. Adv. Cancer Res. 77 (2000) 1-24
    • (2000) Adv. Cancer Res. , vol.77 , pp. 1-24
    • Barker, N.1    Morin, P.J.2    Clevers, H.3
  • 3
    • 33845665838 scopus 로고    scopus 로고
    • Bone anabolic effects of parathyroid hormone are blunted by deletion of the Wnt antagonist secreted frizzled-related protein-1
    • Bodine P.V., Seestaller-Wehr L., Kharode Y.P., Bex F.J., and Komm B.S. Bone anabolic effects of parathyroid hormone are blunted by deletion of the Wnt antagonist secreted frizzled-related protein-1. J. Cell. Physiol. 210 (2007) 352-357
    • (2007) J. Cell. Physiol. , vol.210 , pp. 352-357
    • Bodine, P.V.1    Seestaller-Wehr, L.2    Kharode, Y.P.3    Bex, F.J.4    Komm, B.S.5
  • 5
    • 42549096546 scopus 로고    scopus 로고
    • Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease
    • Bovolenta P., Esteve P., Ruiz J.M., Cisneros E., and Lopez-Rios J. Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease. J. Cell Sci. 121 (2008) 737-746
    • (2008) J. Cell Sci. , vol.121 , pp. 737-746
    • Bovolenta, P.1    Esteve, P.2    Ruiz, J.M.3    Cisneros, E.4    Lopez-Rios, J.5
  • 7
    • 1542378166 scopus 로고    scopus 로고
    • Expression analysis of chick Wnt and frizzled genes and selected inhibitors in early chick patterning
    • Chapman S.C., Brown R., Lees L., Schoenwolf G.C., and Lumsden A. Expression analysis of chick Wnt and frizzled genes and selected inhibitors in early chick patterning. Dev. Dyn. 229 (2004) 668-676
    • (2004) Dev. Dyn. , vol.229 , pp. 668-676
    • Chapman, S.C.1    Brown, R.2    Lees, L.3    Schoenwolf, G.C.4    Lumsden, A.5
  • 8
    • 0346121540 scopus 로고    scopus 로고
    • Neural crest development is regulated by the transcription factor Sox9
    • Cheung M., and Briscoe J. Neural crest development is regulated by the transcription factor Sox9. Development 130 (2003) 5681-5693
    • (2003) Development , vol.130 , pp. 5681-5693
    • Cheung, M.1    Briscoe, J.2
  • 9
    • 3042812309 scopus 로고    scopus 로고
    • Control of roof plate formation by Lmx1a in the developing spinal cord
    • Chizhikov V.V., and Millen K.J. Control of roof plate formation by Lmx1a in the developing spinal cord. Development 131 (2004) 2693-2705
    • (2004) Development , vol.131 , pp. 2693-2705
    • Chizhikov, V.V.1    Millen, K.J.2
  • 10
    • 5044233698 scopus 로고    scopus 로고
    • Mechanisms of roof plate formation in the vertebrate CNS
    • Chizhikov V.V., and Millen K.J. Mechanisms of roof plate formation in the vertebrate CNS. Nat. Rev., Neurosci. 5 (2004) 808-812
    • (2004) Nat. Rev., Neurosci. , vol.5 , pp. 808-812
    • Chizhikov, V.V.1    Millen, K.J.2
  • 11
    • 9444276653 scopus 로고    scopus 로고
    • A vertebrate crossveinless 2 homologue modulates BMP activity and neural crest cell migration
    • Coles E., Christiansen J., Economou A., Bronner-Fraser M., and Wilkinson D.G. A vertebrate crossveinless 2 homologue modulates BMP activity and neural crest cell migration. Development 131 (2004) 5309-5317
    • (2004) Development , vol.131 , pp. 5309-5317
    • Coles, E.1    Christiansen, J.2    Economou, A.3    Bronner-Fraser, M.4    Wilkinson, D.G.5
  • 12
    • 0035164747 scopus 로고    scopus 로고
    • The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate
    • Dottori M., Gross M.K., Labosky P., and Goulding M. The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate. Development 128 (2001) 4127-4138
    • (2001) Development , vol.128 , pp. 4127-4138
    • Dottori, M.1    Gross, M.K.2    Labosky, P.3    Goulding, M.4
  • 13
    • 0343664390 scopus 로고    scopus 로고
    • Early and dynamic expression of cSfrp1 during chick embryo development
    • Esteve P., Morcillo J., and Bovolenta P. Early and dynamic expression of cSfrp1 during chick embryo development. Mech. Dev. 97 (2000) 217-221
    • (2000) Mech. Dev. , vol.97 , pp. 217-221
    • Esteve, P.1    Morcillo, J.2    Bovolenta, P.3
  • 15
    • 0037008478 scopus 로고    scopus 로고
    • Ectodermal Wnt function as a neural crest inducer
    • Garcia-Castro M.I., Marcelle C., and Bronner-Fraser M. Ectodermal Wnt function as a neural crest inducer. Science 297 (2002) 848-851
    • (2002) Science , vol.297 , pp. 848-851
    • Garcia-Castro, M.I.1    Marcelle, C.2    Bronner-Fraser, M.3
  • 16
    • 84924926133 scopus 로고
    • A series of normal stages in the development of the chick embryo
    • Hamburger V., and Hamilton H.L. A series of normal stages in the development of the chick embryo. J. Morphol. 88 (1951) 49-92
    • (1951) J. Morphol. , vol.88 , pp. 49-92
    • Hamburger, V.1    Hamilton, H.L.2
  • 17
    • 33947172588 scopus 로고    scopus 로고
    • Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects
    • Harris M.J., and Juriloff D.M. Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects. Birth Defects Res. A Clin. Mol. Teratol. 79 (2007) 187-210
    • (2007) Birth Defects Res. A Clin. Mol. Teratol. , vol.79 , pp. 187-210
    • Harris, M.J.1    Juriloff, D.M.2
  • 18
    • 0036938392 scopus 로고    scopus 로고
    • Embryonic hydromyelia: cystic dilatation of the lumbosacral neural tube in human embryos
    • Ikenouchi J., Uwabe C., Nakatsu T., Hirose M., and Shiota K. Embryonic hydromyelia: cystic dilatation of the lumbosacral neural tube in human embryos. Acta Neuropathol. 103 (2002) 248-254
    • (2002) Acta Neuropathol. , vol.103 , pp. 248-254
    • Ikenouchi, J.1    Uwabe, C.2    Nakatsu, T.3    Hirose, M.4    Shiota, K.5
  • 19
    • 0036714307 scopus 로고    scopus 로고
    • Secreted Frizzled-related proteins: searching for relationships and patterns
    • Jones S.E., and Jomary C. Secreted Frizzled-related proteins: searching for relationships and patterns. BioEssays 24 (2002) 811-820
    • (2002) BioEssays , vol.24 , pp. 811-820
    • Jones, S.E.1    Jomary, C.2
  • 20
    • 0038783316 scopus 로고    scopus 로고
    • Secreted antagonists of the Wnt signalling pathway
    • Kawano Y., and Kypta R. Secreted antagonists of the Wnt signalling pathway. J. Cell Sci. 116 (2003) 2627-2634
    • (2003) J. Cell Sci. , vol.116 , pp. 2627-2634
    • Kawano, Y.1    Kypta, R.2
  • 21
    • 0037431083 scopus 로고    scopus 로고
    • SOX10 maintains multipotency and inhibits neuronal differentiation of neural crest stem cells
    • Kim J., Lo L., Dormand E., and Anderson D.J. SOX10 maintains multipotency and inhibits neuronal differentiation of neural crest stem cells. Neuron 38 (2003) 17-31
    • (2003) Neuron , vol.38 , pp. 17-31
    • Kim, J.1    Lo, L.2    Dormand, E.3    Anderson, D.J.4
  • 22
    • 0036272896 scopus 로고    scopus 로고
    • Induction of the neural crest: a multigene process
    • Knecht A.K., and Bronner-Fraser M. Induction of the neural crest: a multigene process. Nat. Rev., Genet. 3 (2002) 453-461
    • (2002) Nat. Rev., Genet. , vol.3 , pp. 453-461
    • Knecht, A.K.1    Bronner-Fraser, M.2
  • 24
    • 0033989153 scopus 로고    scopus 로고
    • CRIM1, a novel gene encoding a cysteine-rich repeat protein, is developmentally regulated and implicated in vertebrate CNS development and organogenesis
    • Kolle G., Georgas K., Holmes G.P., Little M.H., and Yamada T. CRIM1, a novel gene encoding a cysteine-rich repeat protein, is developmentally regulated and implicated in vertebrate CNS development and organogenesis. Mech. Dev. 90 (2000) 181-193
    • (2000) Mech. Dev. , vol.90 , pp. 181-193
    • Kolle, G.1    Georgas, K.2    Holmes, G.P.3    Little, M.H.4    Yamada, T.5
  • 25
    • 0037222479 scopus 로고    scopus 로고
    • In ovo electroporation of Crim1 in the developing chick spinal cord
    • Kolle G., Jansen A., Yamada T., and Little M. In ovo electroporation of Crim1 in the developing chick spinal cord. Dev. Dyn. 226 (2003) 107-111
    • (2003) Dev. Dyn. , vol.226 , pp. 107-111
    • Kolle, G.1    Jansen, A.2    Yamada, T.3    Little, M.4
  • 26
    • 0034010982 scopus 로고    scopus 로고
    • BMP-binding modules in chordin: a model for signalling regulation in the extracellular space
    • Larrain J., Bachiller D., Lu B., Agius E., Piccolo S., and De Robertis E.M. BMP-binding modules in chordin: a model for signalling regulation in the extracellular space. Development 127 (2000) 821-830
    • (2000) Development , vol.127 , pp. 821-830
    • Larrain, J.1    Bachiller, D.2    Lu, B.3    Agius, E.4    Piccolo, S.5    De Robertis, E.M.6
  • 27
    • 30344486313 scopus 로고    scopus 로고
    • Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases
    • Lee H.X., Ambrosio A.L., Reversade B., and De Robertis E.M. Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases. Cell 124 (2006) 147-159
    • (2006) Cell , vol.124 , pp. 147-159
    • Lee, H.X.1    Ambrosio, A.L.2    Reversade, B.3    De Robertis, E.M.4
  • 28
    • 1142298447 scopus 로고    scopus 로고
    • Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells
    • Lee H.Y., Kleber M., Hari L., Brault V., Suter U., Taketo M.M., Kemler R., and Sommer L. Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells. Science 303 (2004) 1020-1023
    • (2004) Science , vol.303 , pp. 1020-1023
    • Lee, H.Y.1    Kleber, M.2    Hari, L.3    Brault, V.4    Suter, U.5    Taketo, M.M.6    Kemler, R.7    Sommer, L.8
  • 29
    • 4444220296 scopus 로고    scopus 로고
    • Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cord
    • Lei Q., Zelman A.K., Kuang E., Li S., and Matise M.P. Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cord. Development 131 (2004) 3593-3604
    • (2004) Development , vol.131 , pp. 3593-3604
    • Lei, Q.1    Zelman, A.K.2    Kuang, E.3    Li, S.4    Matise, M.P.5
  • 30
    • 33747833061 scopus 로고    scopus 로고
    • Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube
    • Lei Q., Jeong Y., Misra K., Li S., Zelman A.K., Epstein D.J., and Matise M.P. Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube. Dev. Cell 11 (2006) 325-337
    • (2006) Dev. Cell , vol.11 , pp. 325-337
    • Lei, Q.1    Jeong, Y.2    Misra, K.3    Li, S.4    Zelman, A.K.5    Epstein, D.J.6    Matise, M.P.7
  • 31
    • 0032122460 scopus 로고    scopus 로고
    • Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family
    • Leimeister C., Bach A., and Gessler M. Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family. Mech. Dev. 75 (1998) 29-42
    • (1998) Mech. Dev. , vol.75 , pp. 29-42
    • Leimeister, C.1    Bach, A.2    Gessler, M.3
  • 32
    • 0029162584 scopus 로고
    • Dorsal differentiation of neural plate cells induced by BMP-mediated signals from the epidermal ectoderm
    • Liem K.G., Tremml G., Roelink H., and Jessel T.M. Dorsal differentiation of neural plate cells induced by BMP-mediated signals from the epidermal ectoderm. Cell 82 (1995) 969-979
    • (1995) Cell , vol.82 , pp. 969-979
    • Liem, K.G.1    Tremml, G.2    Roelink, H.3    Jessel, T.M.4
  • 33
    • 33745024718 scopus 로고    scopus 로고
    • The cysteine-rich domain protein KCP is a suppressor of transforming growth factor beta/activin signaling in renal epithelia
    • Lin J., Patel S.R., Wang M., and Dressler G.R. The cysteine-rich domain protein KCP is a suppressor of transforming growth factor beta/activin signaling in renal epithelia. Mol. Cell. Biol. 26 (2006) 4577-4585
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 4577-4585
    • Lin, J.1    Patel, S.R.2    Wang, M.3    Dressler, G.R.4
  • 34
    • 1642303128 scopus 로고    scopus 로고
    • Distinct activities of Msx1 and Msx3 in dorsal neural tube development
    • Liu Y., Helms A.W., and Johnson J.E. Distinct activities of Msx1 and Msx3 in dorsal neural tube development. Development 131 (2004) 1017-1028
    • (2004) Development , vol.131 , pp. 1017-1028
    • Liu, Y.1    Helms, A.W.2    Johnson, J.E.3
  • 35
    • 52349090899 scopus 로고    scopus 로고
    • The Netrin-related domain of Sfrp1 interacts with Wnt ligands and antagonizes their activity in the anterior neural plate
    • Lopez-Rios J., Esteve P., Ruiz J.M., and Bovolenta P. The Netrin-related domain of Sfrp1 interacts with Wnt ligands and antagonizes their activity in the anterior neural plate. Neural Dev. 3 (2008) 19
    • (2008) Neural Dev. , vol.3 , pp. 19
    • Lopez-Rios, J.1    Esteve, P.2    Ruiz, J.M.3    Bovolenta, P.4
  • 36
    • 0032523777 scopus 로고    scopus 로고
    • Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite
    • McMahon J.A., Takada S., Zimmerman L.B., Fan C.M., Harland R.M., and McMahon A.P. Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev. 12 (1998) 1438-1452
    • (1998) Genes Dev. , vol.12 , pp. 1438-1452
    • McMahon, J.A.1    Takada, S.2    Zimmerman, L.B.3    Fan, C.M.4    Harland, R.M.5    McMahon, A.P.6
  • 37
    • 0034677480 scopus 로고    scopus 로고
    • The mouse Dreher gene Lmx1a controls formation of the roof plate in the vertebrate CNS
    • Millonig J.H., Millen K.J., and Hatten M.E. The mouse Dreher gene Lmx1a controls formation of the roof plate in the vertebrate CNS. Nature 403 (2000) 764-769
    • (2000) Nature , vol.403 , pp. 764-769
    • Millonig, J.H.1    Millen, K.J.2    Hatten, M.E.3
  • 38
    • 0043133835 scopus 로고    scopus 로고
    • BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation
    • Moser M., Binder O., Wu Y., Aitsebaomo J., Ren R., Bode C., Bautch V.L., Conlon F.L., and Patterson C. BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation. Mol. Cell. Biol. 23 (2003) 5664-5679
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 5664-5679
    • Moser, M.1    Binder, O.2    Wu, Y.3    Aitsebaomo, J.4    Ren, R.5    Bode, C.6    Bautch, V.L.7    Conlon, F.L.8    Patterson, C.9
  • 42
    • 33645746278 scopus 로고    scopus 로고
    • Sfrp1 and Sfrp2 regulate anteroposterior axis elongation and somite segmentation during mouse embryogenesis
    • Satoh W., Gotoh T., Tsunematsu Y., Aizawa S., and Shimono A. Sfrp1 and Sfrp2 regulate anteroposterior axis elongation and somite segmentation during mouse embryogenesis. Development 133 (2006) 989-999
    • (2006) Development , vol.133 , pp. 989-999
    • Satoh, W.1    Gotoh, T.2    Tsunematsu, Y.3    Aizawa, S.4    Shimono, A.5
  • 43
    • 39549107806 scopus 로고    scopus 로고
    • Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse
    • Satoh W., Matsuyama M., Takemura H., Aizawa S., and Shimono A. Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse. Genesis 46 (2008) 92-103
    • (2008) Genesis , vol.46 , pp. 92-103
    • Satoh, W.1    Matsuyama, M.2    Takemura, H.3    Aizawa, S.4    Shimono, A.5
  • 44
    • 0032757875 scopus 로고    scopus 로고
    • Regulation of the onset of neural crest migration by coordinated activity of BMP4 and Noggin in the dorsal neural tube
    • Sela-Donenfeld D., and Kalcheim C. Regulation of the onset of neural crest migration by coordinated activity of BMP4 and Noggin in the dorsal neural tube. Development 126 (1999) 4749-4762
    • (1999) Development , vol.126 , pp. 4749-4762
    • Sela-Donenfeld, D.1    Kalcheim, C.2
  • 45
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Shi Y., and Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113 (2003) 685-700
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 46
    • 33746218212 scopus 로고    scopus 로고
    • Repressor roles for TCF-4 and Sfrp1 in Wnt signaling in breast cancer
    • Shulewitz M., Soloviev I., Wu T., Koeppen H., Polakis P., and Sakanaka C. Repressor roles for TCF-4 and Sfrp1 in Wnt signaling in breast cancer. Oncogene 25 (2006) 4361-4369
    • (2006) Oncogene , vol.25 , pp. 4361-4369
    • Shulewitz, M.1    Soloviev, I.2    Wu, T.3    Koeppen, H.4    Polakis, P.5    Sakanaka, C.6
  • 47
    • 33745280611 scopus 로고    scopus 로고
    • The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms
    • Stottmann R.W., Berrong M., Matta K., Choi M., and Klingensmith J. The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms. Dev. Biol. 295 (2006) 647-663
    • (2006) Dev. Biol. , vol.295 , pp. 647-663
    • Stottmann, R.W.1    Berrong, M.2    Matta, K.3    Choi, M.4    Klingensmith, J.5
  • 48
    • 0342359186 scopus 로고    scopus 로고
    • Sfrp-1 and sfrp-2 are expressed in overlapping and distinct domains during chick development
    • Terry K., Magan H., Baranski M., and Burrus L.W. Sfrp-1 and sfrp-2 are expressed in overlapping and distinct domains during chick development. Mech. Dev. 97 (2000) 177-182
    • (2000) Mech. Dev. , vol.97 , pp. 177-182
    • Terry, K.1    Magan, H.2    Baranski, M.3    Burrus, L.W.4
  • 49
    • 0033119801 scopus 로고    scopus 로고
    • beta-Catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O., and McCormick F. beta-Catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398 (1999) 422-426
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 50
    • 1242316153 scopus 로고    scopus 로고
    • A postmitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity
    • Thaler J.P., Koo S.J., Kania A., Lettieri K., Andrews S., Cox C., Jessell T.M., and Pfaff S.L. A postmitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity. Neuron 41 (2004) 337-350
    • (2004) Neuron , vol.41 , pp. 337-350
    • Thaler, J.P.1    Koo, S.J.2    Kania, A.3    Lettieri, K.4    Andrews, S.5    Cox, C.6    Jessell, T.M.7    Pfaff, S.L.8
  • 51
    • 7344251776 scopus 로고    scopus 로고
    • Interactions between Bmp-4 and Msx-1 act to restrict gene expression to odontogenic mesenchyme
    • Tucker A.S., Al Khamis A., and Sharpe P.T. Interactions between Bmp-4 and Msx-1 act to restrict gene expression to odontogenic mesenchyme. Dev. Dyn. 212 (1998) 533-539
    • (1998) Dev. Dyn. , vol.212 , pp. 533-539
    • Tucker, A.S.1    Al Khamis, A.2    Sharpe, P.T.3
  • 53
    • 51349143013 scopus 로고    scopus 로고
    • Type IV collagens regulate BMP signalling in Drosophila
    • Wang X., Harris R.E., Bayston L.J., and Ashe H.L. Type IV collagens regulate BMP signalling in Drosophila. Nature 455 (2008) 72-77
    • (2008) Nature , vol.455 , pp. 72-77
    • Wang, X.1    Harris, R.E.2    Bayston, L.J.3    Ashe, H.L.4
  • 54
    • 0141668933 scopus 로고    scopus 로고
    • CRIM1 regulates the rate of processing and delivery of bone morphogenetic proteins to the cell surface
    • Wilkinson L., Kolle G., Wen D., Piper M., Scott J., and Little M. CRIM1 regulates the rate of processing and delivery of bone morphogenetic proteins to the cell surface. J. Biol. Chem. 278 (2003) 34181-34188
    • (2003) J. Biol. Chem. , vol.278 , pp. 34181-34188
    • Wilkinson, L.1    Kolle, G.2    Wen, D.3    Piper, M.4    Scott, J.5    Little, M.6


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