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Volumn 3, Issue 8, 2010, Pages 2495-2516

Non-steroidal anti-inflammatory drugs in the carcinogenesis of the gastrointestinal tract

Author keywords

Colorectal cancer; Cyclooxygenase 2; Esophageal cancer; Gastric cancer; Non steroidal anti inflammatory drugs

Indexed keywords

5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; ACETYLSALICYLIC ACID; APC PROTEIN; CELECOXIB; CYCLINE; CYTOKINE; DEXAMETHASONE; DNA; FAS ANTIGEN; GASTRIN; GROWTH FACTOR; IBUPROFEN; INDOMETACIN; KETOPROFEN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PIROXICAM; PLACEBO; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; PROTEIN P53; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; ROFECOXIB; SCATTER FACTOR; SULINDAC; TILMACOXIB; TRANSFORMING GROWTH FACTOR ALPHA; UNINDEXED DRUG; VALDECOXIB;

EID: 77955589143     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph3082495     Document Type: Article
Times cited : (6)

References (143)
  • 1
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • Balkwill, F.; Mantovani, A. Inflammation and cancer: back to Virchow? Lancet 2001, 357, 539-545.
    • (2001) Lancet , vol.357 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 2
    • 5444256371 scopus 로고    scopus 로고
    • Inflammation as a tumour promoter in cancer induction
    • Philip, M.; Rowley, D.A.; Schreiber, H. Inflammation as a tumour promoter in cancer induction. Semin. Cancer Biol. 2004, 14, 433-439.
    • (2004) Semin. Cancer Biol , vol.14 , pp. 433-439
    • Philip, M.1    Rowley, D.A.2    Schreiber, H.3
  • 3
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens, L.M.; Werb, Z. Inflammation and cancer. Nature 2002, 420, 860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 4
    • 67650151005 scopus 로고    scopus 로고
    • Cancer-related inflammation, the seventh hallmark of cancer: Links to genetic instability
    • Colotta, F.; Allavena, P.; Sica, A.; Garlanda, C.; Mantovani, A. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis 2009, 30, 1073-1081.
    • (2009) Carcinogenesis , vol.30 , pp. 1073-1081
    • Colotta, F.1    Allavena, P.2    Sica, A.3    Garlanda, C.4    Mantovani, A.5
  • 5
    • 3042599473 scopus 로고    scopus 로고
    • Inflammation and cancer. IV. Colorectal cancer in inflammatory bowel disease: The role of inflammation
    • Itzkowitz, S.H.; Yio, X. Inflammation and cancer. IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. Am. J. Physiol. Gastrointest. Liver Physiol. 2004, 287, G7-17.
    • (2004) Am. J. Physiol. Gastrointest. Liver Physiol , vol.287
    • Itzkowitz, S.H.1    Yio, X.2
  • 6
    • 0037357426 scopus 로고    scopus 로고
    • Oxidative stress and ulcerative colitis associated carcinogenesis: Studies in humans and animal models
    • Seril, D.N.; Lia, J.; Yang, G.Y.; Yang, C.S. Oxidative stress and ulcerative colitis associated carcinogenesis: studies in humans and animal models. Carcinogenesis 2003, 24, 353-362.
    • (2003) Carcinogenesis , vol.24 , pp. 353-362
    • Seril, D.N.1    Lia, J.2    Yang, G.Y.3    Yang, C.S.4
  • 7
    • 1642385412 scopus 로고    scopus 로고
    • Inflammation and cancer. II. Role of chronic inflammation and cytokine polymorphisms in the pathogenesis of gastrointestinal malignancy
    • Macarthur, M.; Hold, G.L.; El-Omar, E.M. Inflammation and cancer. II. Role of chronic inflammation and cytokine polymorphisms in the pathogenesis of gastrointestinal malignancy. Am. J. Physiol. Gastrointest. Liver Physiol. 2004, 286, G515-G520.
    • (2004) Am. J. Physiol. Gastrointest. Liver Physiol , vol.286
    • Macarthur, M.1    Hold, G.L.2    El-Omar, E.M.3
  • 8
    • 3242724146 scopus 로고    scopus 로고
    • Inflammation and cancer V. Chronic pancreatitis and pancreatic cancer
    • Whitcomb, D.C. Inflammation and cancer V. Chronic pancreatitis and pancreatic cancer. Am. J. Physiol. Gastrointest. Liver Physiol. 2004, 287, G315-G319.
    • (2004) Am. J. Physiol. Gastrointest. Liver Physiol , vol.287
    • Whitcomb, D.C.1
  • 9
    • 0033571403 scopus 로고    scopus 로고
    • Commentary: At the crossroads of inflammation and tumourigenesis
    • Cordon-Cardo, C.; Prives, C. Commentary: at the crossroads of inflammation and tumourigenesis. J. Exp. Med. 1999, 190, 1367-1370.
    • (1999) J. Exp. Med , vol.190 , pp. 1367-1370
    • Cordon-Cardo, C.1    Prives, C.2
  • 10
    • 0037180812 scopus 로고    scopus 로고
    • Points of control in inflammation
    • Nathan, C. Points of control in inflammation. Nature 2002, 420, 846-852.
    • (2002) Nature , vol.420 , pp. 846-852
    • Nathan, C.1
  • 11
    • 0032112771 scopus 로고    scopus 로고
    • Nitric oxide and oxygen radicals in infection, inflammation, and cancer
    • Maeda, H.; Akaike, H. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistry 1998, 63, 854-865.
    • (1998) Biochemistry , vol.63 , pp. 854-865
    • Maeda, H.1    Akaike, H.2
  • 12
    • 0021143069 scopus 로고
    • Mutagenic activity of tumourassociated macrophages in Salmonella typhimurium strains TA98 and TA100
    • Fulton, A.M.; Loveless, S.E.; Heppner, G.H. Mutagenic activity of tumourassociated macrophages in Salmonella typhimurium strains TA98 and TA100. Cancer Res. 1984, 44, 4308-4311.
    • (1984) Cancer Res , vol.44 , pp. 4308-4311
    • Fulton, A.M.1    Loveless, S.E.2    Heppner, G.H.3
  • 13
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard, J.W. Tumour-educated macrophages promote tumour progression and metastasis. Nat. Rev. Cancer 2004, 4, 71-78.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 14
    • 0035911230 scopus 로고    scopus 로고
    • Inflammatory cells and cancer: Think different!
    • Coussens, L.M.; Werb, Z. Inflammatory cells and cancer: think different! J. Exp. Med. 2001, 193, F23-26.
    • (2001) J. Exp. Med , vol.193
    • Coussens, L.M.1    Werb, Z.2
  • 16
    • 0026725537 scopus 로고
    • Cytokine regulation of endothelial cell function
    • Mantovani, A.; Bussolino, F.; Dejana, E. Cytokine regulation of endothelial cell function. FASEB J. 1992, 6, 2591-2599.
    • (1992) FASEB J , vol.6 , pp. 2591-2599
    • Mantovani, A.1    Bussolino, F.2    Dejana, E.3
  • 17
    • 0034721666 scopus 로고    scopus 로고
    • MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis
    • Coussens, L.M.; Tinkle, C.L.; Hanahan, D.; Werb, Z. MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell 2000, 103, 481-490.
    • (2000) Cell , vol.103 , pp. 481-490
    • Coussens, L.M.1    Tinkle, C.L.2    Hanahan, D.3    Werb, Z.4
  • 18
    • 0347302952 scopus 로고    scopus 로고
    • Cytokines in cancer pathogenesis and cancer therapy
    • Dranoff, G. Cytokines in cancer pathogenesis and cancer therapy. Nat. Rev. Cancer 2004, 4, 11-22.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 11-22
    • Dranoff, G.1
  • 20
    • 0033568215 scopus 로고    scopus 로고
    • Elevated expression of the CC chemokine regulated on activation, normal T cell expressed and secreted (RANTES) in advanced breast carcinoma
    • Luboshits, G.; Shina, S.; Kaplan, O.; Engelberg, S.; Nass, D.; Lifshitz-Mercer, B.; Chaitchik, S.; Keydar, I.; Ben-Baruch, A. Elevated expression of the CC chemokine regulated on activation, normal T cell expressed and secreted (RANTES) in advanced breast carcinoma. Cancer Res. 1999, 59, 4681-4687.
    • (1999) Cancer Res , vol.59 , pp. 4681-4687
    • Luboshits, G.1    Shina, S.2    Kaplan, O.3    Engelberg, S.4    Nass, D.5    Lifshitz-Mercer, B.6    Chaitchik, S.7    Keydar, I.8    Ben-Baruch, A.9
  • 22
    • 0035999153 scopus 로고    scopus 로고
    • The role of cytokines in the epithelial cancer microenvironment
    • Wilson, J.; Balkwill, F. The role of cytokines in the epithelial cancer microenvironment. Semin. Cancer Biol. 2002, 12, 113-120.
    • (2002) Semin. Cancer Biol , vol.12 , pp. 113-120
    • Wilson, J.1    Balkwill, F.2
  • 23
    • 0032948984 scopus 로고    scopus 로고
    • The role of cytokines and chemokines on tumour progression: A review
    • Ardestani, S.K.; Inserra, P.; Solkoff, D.; Watson, R.R. The role of cytokines and chemokines on tumour progression: a review. Cancer Detect. Prev. 1999, 23, 215-225.
    • (1999) Cancer Detect. Prev , vol.23 , pp. 215-225
    • Ardestani, S.K.1    Inserra, P.2    Solkoff, D.3    Watson, R.R.4
  • 24
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D.; Weinberg, R.A. The hallmarks of cancer. Cell 2000, 100, 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 25
    • 0030049390 scopus 로고    scopus 로고
    • Prostaglandin synthase 2
    • Herschman, H.R. Prostaglandin synthase 2. Biochim. Biophys. Acta 1996, 1299, 125-140.
    • (1996) Biochim. Biophys. Acta , vol.1299 , pp. 125-140
    • Herschman, H.R.1
  • 27
    • 0028199075 scopus 로고
    • Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages
    • Reddy, S.T.; Herschman, H.R. Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages. J. Biol. Chem. 1994, 269, 15473-15480.
    • (1994) J. Biol. Chem , vol.269 , pp. 15473-15480
    • Reddy, S.T.1    Herschman, H.R.2
  • 28
    • 0037108979 scopus 로고    scopus 로고
    • COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression
    • Chandrasekharan, N.V.; Dai, H.; Roos, K.L.; Evanson, N.K.; Tomsik, J.; Elton, T.S.; Simmons, D.L. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc. Natl. Acad. Sci. USA 2002, 99, 13926-13931.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13926-13931
    • Chandrasekharan, N.V.1    Dai, H.2    Roos, K.L.3    Evanson, N.K.4    Tomsik, J.5    Elton, T.S.6    Simmons, D.L.7
  • 29
    • 0034471496 scopus 로고    scopus 로고
    • Biochemistry of cyclooxygenase COX-2 inhibitors and molecular pathology of COX- 2 in neoplasia
    • Fosslien, E. Biochemistry of cyclooxygenase COX-2 inhibitors and molecular pathology of COX- 2 in neoplasia. Crit. Rev. Clin. Lab. Sci. 2000, 37, 431-502.
    • (2000) Crit. Rev. Clin. Lab. Sci , vol.37 , pp. 431-502
    • Fosslien, E.1
  • 31
    • 4444262310 scopus 로고    scopus 로고
    • Pharmacology and signaling of prostaglandin receptors: Multiple roles in inflammation and immune modulation
    • Hata, A.N.; Breyer, R.M. Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation. Pharmacol. Ther. 2004, 103, 147-166.
    • (2004) Pharmacol. Ther , vol.103 , pp. 147-166
    • Hata, A.N.1    Breyer, R.M.2
  • 32
    • 11144310564 scopus 로고    scopus 로고
    • An overview on biological mechanisms of PPARs
    • Kota, B.P.; Huang, T.H.; Roufogalis, B.D. An overview on biological mechanisms of PPARs. Pharmacol. Res. 2005, 51, 85-94.
    • (2005) Pharmacol. Res , vol.51 , pp. 85-94
    • Kota, B.P.1    Huang, T.H.2    Roufogalis, B.D.3
  • 33
    • 35348994840 scopus 로고    scopus 로고
    • PGE2 inhibits apoptosis in human adenocarcinoma Caco-2 cell line through Ras-PI3K association and cAMP-dependent kinase A activation. Am. J. Physiol. Gastrointest
    • Leone, V.; di Palma, A.; Ricchi, P.; Acquaviva, F.; Giannouli, M.; Di Prisco, A.M.; Iuliano, F.; Acquaviva, A.M. PGE2 inhibits apoptosis in human adenocarcinoma Caco-2 cell line through Ras-PI3K association and cAMP-dependent kinase A activation. Am. J. Physiol. Gastrointest. Liver Physiol. 2007, 293, G673-681.
    • (2007) Liver Physiol , vol.293
    • Leone, V.1    di Palma, A.2    Ricchi, P.3    Acquaviva, F.4    Giannouli, M.5    di Prisco, A.M.6    Iuliano, F.7    Acquaviva, A.M.8
  • 34
    • 0036142958 scopus 로고    scopus 로고
    • Gene transfer of thromboxane A(2) synthase and prostaglandin I (2) synthase antithetically altered tumour angiogenesis and tumour growth
    • Pradono, P.; Tazawa, R.; Maemondo, M.; Tanaka, M.; Usui, K.; Saijo, Y.; Hagiwara, K.; Nukiwa, T. Gene transfer of thromboxane A(2) synthase and prostaglandin I (2) synthase antithetically altered tumour angiogenesis and tumour growth. Cancer Res. 2002, 62, 63-66.
    • (2002) Cancer Res , vol.62 , pp. 63-66
    • Pradono, P.1    Tazawa, R.2    Maemondo, M.3    Tanaka, M.4    Usui, K.5    Saijo, Y.6    Hagiwara, K.7    Nukiwa, T.8
  • 36
    • 16444385003 scopus 로고    scopus 로고
    • Prostaglandin E2 enhances intestinal adenoma growth via activation of the Ras-mitogen-activated protein kinase cascade
    • Wang, D.; Buchanan, F.G.; Wang, H.; Dey, S.K.; DuBois, R.N. Prostaglandin E2 enhances intestinal adenoma growth via activation of the Ras-mitogen-activated protein kinase cascade. Cancer Res. 2005, 65, 1822-1829.
    • (2005) Cancer Res , vol.65 , pp. 1822-1829
    • Wang, D.1    Buchanan, F.G.2    Wang, H.3    Dey, S.K.4    Dubois, R.N.5
  • 37
    • 0036157485 scopus 로고    scopus 로고
    • Many actions of cyclooxygenase-2 in cellular dynamics and in cancer
    • Cao, Y.; Prescott, S.M. Many actions of cyclooxygenase-2 in cellular dynamics and in cancer. J. Cell. Physiol. 2002, 190, 279-286.
    • (2002) J. Cell. Physiol , vol.190 , pp. 279-286
    • Cao, Y.1    Prescott, S.M.2
  • 38
    • 0031984810 scopus 로고    scopus 로고
    • Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells
    • Sheng, H.; Shao, J.; Morrow, J.D., Beauchamp, R.D.; DuBois, R.N. Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. Cancer Res. 1998, 58, 362-366.
    • (1998) Cancer Res , vol.58 , pp. 362-366
    • Sheng, H.1    Shao, J.2    Morrow, J.D.3    Beauchamp, R.D.4    Dubois, R.N.5
  • 39
    • 0035914407 scopus 로고    scopus 로고
    • Positive and negative regulation of NF-kappa B by COX-2: Roles of different prostaglandins
    • Poligone, B.; Baldwin, A.S. Positive and negative regulation of NF-kappa B by COX-2: roles of different prostaglandins. J. Biol. Chem. 2001, 276, 38658-38664.
    • (2001) J. Biol. Chem , vol.276 , pp. 38658-38664
    • Poligone, B.1    Baldwin, A.S.2
  • 43
    • 0033556002 scopus 로고    scopus 로고
    • Edelmann; W.; Kucherlapati; R.; Bertagnolli, M.M. Genotype-phenotype correlation in murine Apc mutation: Differences in enterocyte migration and response to sulindac
    • Mahmoud, N.N.; Bilinski, R.T.; Churchill, M.R.; Edelmann; W.; Kucherlapati; R.; Bertagnolli, M.M. Genotype-phenotype correlation in murine Apc mutation: differences in enterocyte migration and response to sulindac. Cancer Res. 1999, 59, 353-359.
    • (1999) Cancer Res , vol.59 , pp. 353-359
    • Mahmoud, N.N.1    Bilinski, R.T.2    Churchill, M.R.3
  • 45
    • 0031000902 scopus 로고    scopus 로고
    • Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: Apoptotic index as a biomarker in colon cancer chemoprevention and promotion
    • Samaha, H.S.; Kelloff, G.J.; Steele, V.; Rao, C.V.; Reddy, B.S. Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion. Cancer Res. 1997, 57, 1301-1305.
    • (1997) Cancer Res , vol.57 , pp. 1301-1305
    • Samaha, H.S.1    Kelloff, G.J.2    Steele, V.3    Rao, C.V.4    Reddy, B.S.5
  • 46
    • 0034477132 scopus 로고    scopus 로고
    • Induction of apoptosis by JTE-522, a specific cyclooxygenase-2 inhibitor, in human gastric cancer cell lines
    • Uefuji, K.; Ichikura, T.; Shinomiya, N.; Mochizuki, H. Induction of apoptosis by JTE-522, a specific cyclooxygenase-2 inhibitor, in human gastric cancer cell lines. Anticancer Res. 2000, 20, 4279-4284.
    • (2000) Anticancer Res , vol.20 , pp. 4279-4284
    • Uefuji, K.1    Ichikura, T.2    Shinomiya, N.3    Mochizuki, H.4
  • 48
    • 0035650943 scopus 로고    scopus 로고
    • COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib
    • Grösch, S.; Tegeder, I.; Niederberger, E.; Bräutigam, L.; Geisslinger, G. COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib. FASEB J. 2001, 15, 2742-2744.
    • (2001) FASEB J , vol.15 , pp. 2742-2744
    • Grösch, S.1    Tegeder, I.2    Niederberger, E.3    Bräutigam, L.4    Geisslinger, G.5
  • 49
    • 0033199017 scopus 로고    scopus 로고
    • Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: Growth inhibition by nonsteroidal anti-inflammatory drugs
    • Molina, M.A.; Sitja-Arnau, M.; Le moine, M.G.; Frazier, M.L.; Sinicrope, F.A. Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: growth inhibition by nonsteroidal anti-inflammatory drugs. Cancer Res. 1999, 59, 4356-4362.
    • (1999) Cancer Res , vol.59 , pp. 4356-4362
    • Molina, M.A.1    Sitja-Arnau, M.2    le Moine, M.G.3    Frazier, M.L.4    Sinicrope, F.A.5
  • 50
    • 0003504049 scopus 로고    scopus 로고
    • Cyclooxygenase regulates angiogenesis induced by colon cancer cells
    • Tsujii, M.; Kawano, S.; Tsuji, S.; Sawaoka, H.; Hori, M.; DuBois, R.N. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 1998, 93, 705-716.
    • (1998) Cell , vol.93 , pp. 705-716
    • Tsujii, M.1    Kawano, S.2    Tsuji, S.3    Sawaoka, H.4    Hori, M.5    Dubois, R.N.6
  • 51
    • 0034894046 scopus 로고    scopus 로고
    • UV radiation and prostaglandin E2 up-regulate vascular endothelial growth factor (VEGF) in cultured human fibroblasts
    • Trompezinski, S.; Pernet, I.; Schmitt, D.; Viac, J. UV radiation and prostaglandin E2 up-regulate vascular endothelial growth factor (VEGF) in cultured human fibroblasts. Inflamm. Res. 2001, 50, 422-427.
    • (2001) Inflamm. Res , vol.50 , pp. 422-427
    • Trompezinski, S.1    Pernet, I.2    Schmitt, D.3    Viac, J.4
  • 53
    • 0033534785 scopus 로고    scopus 로고
    • Basic fibroblast growth factor induces cyclooxygenase-2 expression in endothelial cells derived from bone
    • Kage, K.; Fujita, N.; Oh-hara, T.; Ogata, E.; Fujita, T.; Tsuruo, T. Basic fibroblast growth factor induces cyclooxygenase-2 expression in endothelial cells derived from bone. Biochem. Biophys. Res. Commun. 1999, 254, 259-263.
    • (1999) Biochem. Biophys. Res. Commun , vol.254 , pp. 259-263
    • Kage, K.1    Fujita, N.2    Oh-Hara, T.3    Ogata, E.4    Fujita, T.5    Tsuruo, T.6
  • 55
    • 33746123520 scopus 로고    scopus 로고
    • Direct transcriptional up-regulation of cyclooxygenase-2 by hypoxia-inducible factor (HIF)-1 promotes colorectal tumour cell survival and enhances HIF-1 transcriptional activity during hypoxia
    • Kaidi, A.; Qualtrough, D.; Williams, A.C.; Paraskeva, C. Direct transcriptional up-regulation of cyclooxygenase-2 by hypoxia-inducible factor (HIF)-1 promotes colorectal tumour cell survival and enhances HIF-1 transcriptional activity during hypoxia. Cancer Res. 2006, 66, 6683-6691.
    • (2006) Cancer Res , vol.66 , pp. 6683-6691
    • Kaidi, A.1    Qualtrough, D.2    Williams, A.C.3    Paraskeva, C.4
  • 56
    • 0034791297 scopus 로고    scopus 로고
    • Paroz; C., Rüegg, C. NSAIDs inhibit alpha V beta 3integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis
    • Dormond, O.; Foletti, A., Paroz; C., Rüegg, C. NSAIDs inhibit alpha V beta 3integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis. Nat. Med. 2001, 7, 1041-1047.
    • (2001) Nat. Med , vol.7 , pp. 1041-1047
    • Dormond, O.1    Foletti, A.2
  • 57
    • 22144439081 scopus 로고    scopus 로고
    • Tumour antigen-specific T helper cells in cancer immunity and immunotherapy
    • Knutson, K.L.; Disis, M.L. Tumour antigen-specific T helper cells in cancer immunity and immunotherapy. Cancer Immunol. Immunother. 2005, 54, 721-728.
    • (2005) Cancer Immunol. Immunother , vol.54 , pp. 721-728
    • Knutson, K.L.1    Disis, M.L.2
  • 60
    • 12844255778 scopus 로고    scopus 로고
    • Prostaglandin E2 regulates the complement inhibitor CD55/decay-accelerating factor in colorectal cancer
    • Holla, V.R.; Wang, D.; Brown, J.R.; Mann, J.R.; Katkuri, S.; DuBois, R.N. Prostaglandin E2 regulates the complement inhibitor CD55/decay-accelerating factor in colorectal cancer. J. Biol. Chem. 2005, 280, 476-483.
    • (2005) J. Biol. Chem , vol.280 , pp. 476-483
    • Holla, V.R.1    Wang, D.2    Brown, J.R.3    Mann, J.R.4    Katkuri, S.5    Dubois, R.N.6
  • 62
    • 0037311125 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice
    • Yao, M.; Kargman, S.; Lam, E.C.; Kelly, C.R.; Zheng, Y.; Luk, P.; Kwong, E.; Evans, J.F.; Wolfe, M.M. Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice. Cancer Res. 2003, 63, 586-592.
    • (2003) Cancer Res , vol.63 , pp. 586-592
    • Yao, M.1    Kargman, S.2    Lam, E.C.3    Kelly, C.R.4    Zheng, Y.5    Luk, P.6    Kwong, E.7    Evans, J.F.8    Wolfe, M.M.9
  • 64
    • 0028065229 scopus 로고
    • Comparative toxicity of non-steroidal antiinflammatory agents
    • Singh, G.; Ramey, D.R.; Morfeld, D.; Fries, J.F. Comparative toxicity of non-steroidal antiinflammatory agents. Pharmacol. Ther. 1994, 62, 175-191.
    • (1994) Pharmacol. Ther , vol.62 , pp. 175-191
    • Singh, G.1    Ramey, D.R.2    Morfeld, D.3    Fries, J.F.4
  • 65
    • 0028030516 scopus 로고
    • Intestinal toxicity of non-steroidal anti-inflammatory drugs
    • Bjarnason, I.; Macpherson, A.J.S. Intestinal toxicity of non-steroidal anti-inflammatory drugs. Pharmacol. Ther. 1994, 62, 145-157.
    • (1994) Pharmacol. Ther , vol.62 , pp. 145-157
    • Bjarnason, I.1    Macpherson, A.J.S.2
  • 66
    • 0026788165 scopus 로고
    • Gastrointestinal damage associated with the use of non-steroidal anti-inflammatory drugs
    • Allison, M.C.; Howatson, A.G.; Torrance, C.J.; Lee, F.D.; Russell, R.I. Gastrointestinal damage associated with the use of non-steroidal anti-inflammatory drugs, N. Engl. J. Med. 1992, 327, 749-754.
    • (1992) N. Engl. J. Med , vol.327 , pp. 749-754
    • Allison, M.C.1    Howatson, A.G.2    Torrance, C.J.3    Lee, F.D.4    Russell, R.I.5
  • 68
    • 0028398324 scopus 로고
    • Regulation of prostaglandin synthesis by glucocorticoids
    • Masferrer, J.L.; Seibert, K. Regulation of prostaglandin synthesis by glucocorticoids. Receptor 1994, 4, 25-30.
    • (1994) Receptor , vol.4 , pp. 25-30
    • Masferrer, J.L.1    Seibert, K.2
  • 69
    • 0027942421 scopus 로고
    • Herschman, H.R. In vivo glucocorticoids regulate cyclooxygenase-2 but not cyclooxygenase-1 in peritoneal macrophages
    • Masferrer, J.L.; Reddy, S.T.; Zweifel, B.S.; Seibert, K.; Needleman, P.; Gilbert, R.S.; Herschman, H.R. In vivo glucocorticoids regulate cyclooxygenase-2 but not cyclooxygenase-1 in peritoneal macrophages. J. Pharmacol. Exp. Ther. 1994, 270, 1340-1344.
    • (1994) J. Pharmacol. Exp. Ther , vol.270 , pp. 1340-1344
    • Masferrer, J.L.1    Reddy, S.T.2    Zweifel, B.S.3    Seibert, K.4    Needleman, P.5    Gilbert, R.S.6
  • 70
    • 6044274282 scopus 로고    scopus 로고
    • Coxibs and cardiovascular disease
    • Fitzgerald, G.A. Coxibs and cardiovascular disease. N. Engl. J. Med. 2004, 351, 1709-1711.
    • (2004) N. Engl. J. Med , vol.351 , pp. 1709-1711
    • Fitzgerald, G.A.1
  • 71
    • 6044267892 scopus 로고    scopus 로고
    • Failing the public health: Rofecoxib, Merck, and the FDA
    • Topol, E.J. Failing the public health: rofecoxib, Merck, and the FDA. N. Engl. J. Med. 2004, 351, 1707-1709.
    • (2004) N. Engl. J. Med , vol.351 , pp. 1707-1709
    • Topol, E.J.1
  • 72
    • 0035045145 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence
    • Morris, C.D.; Armstrong, G.R.; Bigley, G.; Green, H.; Attwood, S.E. Cyclooxygenase-2 expression in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence. Am. J. Gastroenterol. 2001, 96, 990-996.
    • (2001) Am. J. Gastroenterol , vol.96 , pp. 990-996
    • Morris, C.D.1    Armstrong, G.R.2    Bigley, G.3    Green, H.4    Attwood, S.E.5
  • 73
    • 0034102269 scopus 로고    scopus 로고
    • Cyclooxygenase 2 expression in Barrett's esophagus and adenocarcinoma: Ex vivo induction by bile salts and acid exposure
    • Shirvani, V.N.; Ouatu-Lascar, R.; Kaur, B.S.; Omary, M.B.; Triadafilopoulos, G. Cyclooxygenase 2 expression in Barrett's esophagus and adenocarcinoma: Ex vivo induction by bile salts and acid exposure. Gastroenterology 2000, 118, 487-496.
    • (2000) Gastroenterology , vol.118 , pp. 487-496
    • Shirvani, V.N.1    Ouatu-Lascar, R.2    Kaur, B.S.3    Omary, M.B.4    Triadafilopoulos, G.5
  • 74
    • 0035211027 scopus 로고    scopus 로고
    • Duodenal reflux induces cyclooxygenase-2 in the esophageal mucosa of rats: Evidence for involvement of bile acids
    • Zhang, F.; Altorki, N.K.; Wu, Y.C.; Soslow, R.A.; Subbaramaiah, K.; Dannenberg, A.J. Duodenal reflux induces cyclooxygenase-2 in the esophageal mucosa of rats: evidence for involvement of bile acids. Gastroenterology 2001, 121, 1391-1399.
    • (2001) Gastroenterology , vol.121 , pp. 1391-1399
    • Zhang, F.1    Altorki, N.K.2    Wu, Y.C.3    Soslow, R.A.4    Subbaramaiah, K.5    Dannenberg, A.J.6
  • 75
    • 59649106758 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs and risk of gastric and oesophageal adenocarcinomas: Results from a cohort study and a meta-analysis
    • Abnet, C.C.; Freedman, N.D.; Kamangar, F.; Leitzmann, M.F.; Hollenbeck, A.R.; Schatzkin, A. Non-steroidal anti-inflammatory drugs and risk of gastric and oesophageal adenocarcinomas: results from a cohort study and a meta-analysis. Br. J. Cancer 2009, 100, 551-557.
    • (2009) Br. J. Cancer , vol.100 , pp. 551-557
    • Abnet, C.C.1    Freedman, N.D.2    Kamangar, F.3    Leitzmann, M.F.4    Hollenbeck, A.R.5    Schatzkin, A.6
  • 77
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • Tsujii, M.; DuBois, R.N. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 1995, 83, 493-501.
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    Dubois, R.N.2
  • 79
    • 0036308913 scopus 로고    scopus 로고
    • Rofecoxib inhibits cyclooxygenase 2 expression and activity and reduces cell proliferation in Barrett's esophagus
    • Kaur, B.S.; Khamnehei, N.; Iravani, M.; Namburu, S.S.; Lin, O.; Triadafilopoulos, G. Rofecoxib inhibits cyclooxygenase 2 expression and activity and reduces cell proliferation in Barrett's esophagus. Gastroenterology 2002, 123, 60-67.
    • (2002) Gastroenterology , vol.123 , pp. 60-67
    • Kaur, B.S.1    Khamnehei, N.2    Iravani, M.3    Namburu, S.S.4    Lin, O.5    Triadafilopoulos, G.6
  • 80
    • 0034667497 scopus 로고    scopus 로고
    • Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells
    • Souza, R.F.; Shewmake, K.; Beer, D.G.; Cryer, B.; Spechler, S.J. Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells. Cancer Res. 2000, 60, 5767-5772.
    • (2000) Cancer Res , vol.60 , pp. 5767-5772
    • Souza, R.F.1    Shewmake, K.2    Beer, D.G.3    Cryer, B.4    Spechler, S.J.5
  • 82
    • 0035067428 scopus 로고    scopus 로고
    • Suppression of N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumourigenesis in F344 rats by JTE-522, a selective COX-2 inhibitor
    • Li, Z.; Shimada, Y.; Kawabe, A.; Sato, F.; Maeda, M.; Komoto, I.; Hong, T.; Ding, Y.; Kaganoi, J.; Imamura, M. Suppression of N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumourigenesis in F344 rats by JTE-522, a selective COX-2 inhibitor. Carcinogenesis 2001, 22, 547-551.
    • (2001) Carcinogenesis , vol.22 , pp. 547-551
    • Li, Z.1    Shimada, Y.2    Kawabe, A.3    Sato, F.4    Maeda, M.5    Komoto, I.6    Hong, T.7    Ding, Y.8    Kaganoi, J.9    Imamura, M.10
  • 85
    • 0027065034 scopus 로고
    • Human gastric carcinogenesis: A multistep and multifactorial process - First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention
    • Correa, P. Human gastric carcinogenesis: a multistep and multifactorial process - First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res. 1992, 52, 6735-6740.
    • (1992) Cancer Res , vol.52 , pp. 6735-6740
    • Correa, P.1
  • 89
    • 0034495173 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in Helicobacter pylori-associated premalignant and malignant gastric lesions
    • Sung, J.J.; Leung, W.K.; Go, M.Y.; To, K.F.; Cheng, A.S.; Ng, E.K.; Chan, F.K. Cyclooxygenase-2 expression in Helicobacter pylori-associated premalignant and malignant gastric lesions. Am. J. Pathol. 2000, 157, 729-735.
    • (2000) Am. J. Pathol , vol.157 , pp. 729-735
    • Sung, J.J.1    Leung, W.K.2    Go, M.Y.3    To, K.F.4    Cheng, A.S.5    Ng, E.K.6    Chan, F.K.7
  • 93
    • 0036229792 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is increased in early intestinal-type gastric cancer and gastric mucosa with intestinal metaplasia
    • Yamagata, R.; Shimoyama, T.; Fukuda, S.; Yoshimura, T.; Tanaka, M.; Munakata, A. Cyclooxygenase-2 expression is increased in early intestinal-type gastric cancer and gastric mucosa with intestinal metaplasia. Eur. J. Gastroenterol. Hepatol. 2002, 14, 359-363.
    • (2002) Eur. J. Gastroenterol. Hepatol , vol.14 , pp. 359-363
    • Yamagata, R.1    Shimoyama, T.2    Fukuda, S.3    Yoshimura, T.4    Tanaka, M.5    Munakata, A.6
  • 94
    • 0035143065 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 in human gastric adenomas and adenocarcinomas
    • Uefuji, K.; Ichikura, T.; Mochizuki, H. Expression of cyclooxygenase-2 in human gastric adenomas and adenocarcinomas. J. Surg. Oncol. 2001, 76, 26-30.
    • (2001) J. Surg. Oncol , vol.76 , pp. 26-30
    • Uefuji, K.1    Ichikura, T.2    Mochizuki, H.3
  • 95
    • 0037442171 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 and clinicopathologic features in human gastric adenocarcinoma
    • Xue, Y.W.; Zhang, Q.F.; Zhu, Z.B.; Wang, Q.; Fu, S.B. Expression of cyclooxygenase-2 and clinicopathologic features in human gastric adenocarcinoma. World J. Gastroenterol. 2003, 9, 250-253.
    • (2003) World J. Gastroenterol , vol.9 , pp. 250-253
    • Xue, Y.W.1    Zhang, Q.F.2    Zhu, Z.B.3    Wang, Q.4    Fu, S.B.5
  • 97
    • 0032810016 scopus 로고    scopus 로고
    • Overexpression of Cyclooxygenase-2 protein is less frequent in gastric cancers with microsatellite instability
    • Yamamoto, H.; Itoh, F.; Fukushima, H.; Hinoda, Y.; Imai, K. Overexpression of Cyclooxygenase-2 protein is less frequent in gastric cancers with microsatellite instability. Int. J. Cancer. 1999, 84, 400-403.
    • (1999) Int. J. Cancer , vol.84 , pp. 400-403
    • Yamamoto, H.1    Itoh, F.2    Fukushima, H.3    Hinoda, Y.4    Imai, K.5
  • 98
    • 0037910076 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is associated with well-differentiated and intestinal-type pathways in gastric carcinogenesis
    • Joo, Y.E.; Oh, W.T.; Rew, J.S.; Park, C.S.; Choi, S.K.; Kim, S.J. Cyclooxygenase-2 expression is associated with well-differentiated and intestinal-type pathways in gastric carcinogenesis. Digestion 2002, 66, 222-229.
    • (2002) Digestion , vol.66 , pp. 222-229
    • Joo, Y.E.1    Oh, W.T.2    Rew, J.S.3    Park, C.S.4    Choi, S.K.5    Kim, S.J.6
  • 99
    • 0037344368 scopus 로고    scopus 로고
    • Influence of gastrin on the expression of cyclooxygenase-2, hepatocyte growth factor and apoptosis-related proteins in gastric epithelial cells
    • Konturek, P.C.; Kania, J.; Kukharsky, V.; Ocker, S.; Hahn, E.G.; Konturek, S.J. Influence of gastrin on the expression of cyclooxygenase-2, hepatocyte growth factor and apoptosis-related proteins in gastric epithelial cells. J. Physiol. Pharmacol. 2003, 54, 17-32.
    • (2003) J. Physiol. Pharmacol , vol.54 , pp. 17-32
    • Konturek, P.C.1    Kania, J.2    Kukharsky, V.3    Ocker, S.4    Hahn, E.G.5    Konturek, S.J.6
  • 103
    • 0242570820 scopus 로고    scopus 로고
    • Influence of COX-2 inhibition by rofecoxib on serum and tumour progastrin and gastrin levels and expression of PPAR gamma and apoptosisrelated proteins in gastric cancer patients
    • Konturek, P.C.; Konturek, S.J.; Bielanski, W.; Kania, J.; Zuchowicz, M.; Hartwich, A.; Rehfeld, J.F.; Hahn, E.G. Influence of COX-2 inhibition by rofecoxib on serum and tumour progastrin and gastrin levels and expression of PPAR gamma and apoptosisrelated proteins in gastric cancer patients. Dig. Dis. Sci. 2003, 48, 2005-2017.
    • (2003) Dig. Dis. Sci , vol.48 , pp. 2005-2017
    • Konturek, P.C.1    Konturek, S.J.2    Bielanski, W.3    Kania, J.4    Zuchowicz, M.5    Hartwich, A.6    Rehfeld, J.F.7    Hahn, E.G.8
  • 104
    • 0033973713 scopus 로고    scopus 로고
    • Molecular pathology of cyclooxygenase-2 in neoplasia
    • Fosslien, E. Molecular pathology of cyclooxygenase-2 in neoplasia. Ann. Clin. Lab. Sci. 2000, 30, 3-21.
    • (2000) Ann. Clin. Lab. Sci , vol.30 , pp. 3-21
    • Fosslien, E.1
  • 105
    • 0032871514 scopus 로고    scopus 로고
    • Potential utility of COX-2 inhibitors in chemoprevention and chemotherapy
    • Koki, A.T.; Leahy, K.M.; Masferrer, J.L. Potential utility of COX-2 inhibitors in chemoprevention and chemotherapy. Expert Opin. Investig. Drugs 1999, 8, 1623-1638.
    • (1999) Expert Opin. Investig. Drugs , vol.8 , pp. 1623-1638
    • Koki, A.T.1    Leahy, K.M.2    Masferrer, J.L.3
  • 106
    • 0034769736 scopus 로고    scopus 로고
    • Review: Molecular pathology of cyclooxygenase-2 in cancer-induced angiogenesis
    • Fosslien, E. Review: molecular pathology of cyclooxygenase-2 in cancer-induced angiogenesis. Ann. Clin. Lab. Sci. 2001, 31, 325-348.
    • (2001) Ann. Clin. Lab. Sci , vol.31 , pp. 325-348
    • Fosslien, E.1
  • 107
    • 0027302966 scopus 로고
    • Inhibitory effects of indomethacin on growth and proliferation of gastric carcinoma cells KATO III
    • Fujiwara, Y.; Tarnawski, A.; Fujiwara, K.; Arakawa, T.; Kobayashi, K. Inhibitory effects of indomethacin on growth and proliferation of gastric carcinoma cells KATO III. J. Physiol. Pharmacol. 1993, 44, 147-153.
    • (1993) J. Physiol. Pharmacol , vol.44 , pp. 147-153
    • Fujiwara, Y.1    Tarnawski, A.2    Fujiwara, K.3    Arakawa, T.4    Kobayashi, K.5
  • 108
    • 0031799475 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice
    • Sawaoka, H.; Kawano, S.; Tsuji, S.; Gunawan, E.S.; Takei, Y.; Nagano, K.; Hori, M. Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice. Am. J. Physiol. 1998, 274, G1061-G1067.
    • (1998) Am. J. Physiol , vol.274
    • Sawaoka, H.1    Kawano, S.2    Tsuji, S.3    Gunawan, E.S.4    Takei, Y.5    Nagano, K.6    Hori, M.7
  • 109
    • 0029087525 scopus 로고
    • Indomethacin interferes with epidermal growth factor binding and proliferative response of gastric KATO III cells
    • Fujiwara, Y.; Schmassmann, A.; Arakawa, T.; Halter, F.; Tarnawski, A. Indomethacin interferes with epidermal growth factor binding and proliferative response of gastric KATO III cells. Digestion 1995, 56, 364-369.
    • (1995) Digestion , vol.56 , pp. 364-369
    • Fujiwara, Y.1    Schmassmann, A.2    Arakawa, T.3    Halter, F.4    Tarnawski, A.5
  • 110
    • 9744251631 scopus 로고    scopus 로고
    • The selective cyclooxy- genase-2 inhibitor nimesulide prevents Helicobacter pyloriassociated gastric cancer development in a mouse model
    • Nam, K.T.; Hahm, K.B.; Oh, S.Y.; Yeo, M.; Han, S.U.; Ahn, B.; Kim, Y.B.; Kang, J.S.; Jang, D.D.; Yang, K.H.; Kim, D.Y. The selective cyclooxy- genase-2 inhibitor nimesulide prevents Helicobacter pyloriassociated gastric cancer development in a mouse model. Clin. Cancer Res. 2004, 10, 8105-8113.
    • (2004) Clin. Cancer Res , vol.10 , pp. 8105-8113
    • Nam, K.T.1    Hahm, K.B.2    Oh, S.Y.3    Yeo, M.4    Han, S.U.5    Ahn, B.6    Kim, Y.B.7    Kang, J.S.8    Jang, D.D.9    Yang, K.H.10    Kim, D.Y.11
  • 111
    • 2342587509 scopus 로고    scopus 로고
    • Hyperplastic gastric tumours induced by activated macrophage in COX-2/mPGES-1 transgenic mice
    • Oshima, H.; Oshima, M.; Inaba, K.; Taketo, M.M. Hyperplastic gastric tumours induced by activated macrophage in COX-2/mPGES-1 transgenic mice. EMBO J. 2004, 23, 1669-1678.
    • (2004) EMBO J , vol.23 , pp. 1669-1678
    • Oshima, H.1    Oshima, M.2    Inaba, K.3    Taketo, M.M.4
  • 116
    • 61549105593 scopus 로고    scopus 로고
    • Chemoprevention of oesophageal cancer and the AspECT trial
    • Das, D.; Chilton, A.P.; Jankowski, J.A. Chemoprevention of oesophageal cancer and the AspECT trial. Recent Results Cancer Res. 2009, 181, 161-169.
    • (2009) Recent Results Cancer Res , vol.181 , pp. 161-169
    • Das, D.1    Chilton, A.P.2    Jankowski, J.A.3
  • 118
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumourigenesis
    • Fearon, E.R.; Vogelstein, B. A genetic model for colorectal tumourigenesis. Cell 1990 61, 759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 119
    • 1242314857 scopus 로고    scopus 로고
    • Role of cyclooxygenase-2 in colorectal cancer
    • Sinicrope, F.A.; Gill, S. Role of cyclooxygenase-2 in colorectal cancer. Cancer Metastasis Rev. 2004, 23, 63-75.
    • (2004) Cancer Metastasis Rev , vol.23 , pp. 63-75
    • Sinicrope, F.A.1    Gill, S.2
  • 120
    • 0029913633 scopus 로고    scopus 로고
    • Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumours
    • DuBois, R.N.; Radhika, A.; Reddy, B.S.; Entingh, A.J. Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumours. Gastroenterology 1996, 110, 1259-1262.
    • (1996) Gastroenterology , vol.110 , pp. 1259-1262
    • Dubois, R.N.1    Radhika, A.2    Reddy, B.S.3    Entingh, A.J.4
  • 124
    • 0032694425 scopus 로고    scopus 로고
    • Differential expression of cyclooxygenase 2 in human colorectal cancer
    • Dimberg, J.; Samuelsson, A.; Hugander, A.; Soderkvist, P. Differential expression of cyclooxygenase 2 in human colorectal cancer. Gut 1999, 45, 730-732.
    • (1999) Gut , vol.45 , pp. 730-732
    • Dimberg, J.1    Samuelsson, A.2    Hugander, A.3    Soderkvist, P.4
  • 128
    • 0030952695 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential
    • Tsujii, M.; Kawano, S.; DuBois, R.N. Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc. Natl. Acad. Sci. USA 1997, 94, 3336-3340.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3336-3340
    • Tsujii, M.1    Kawano, S.2    Dubois, R.N.3
  • 129
    • 0034650771 scopus 로고    scopus 로고
    • Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis
    • Reddy, B.S.; Hirose, Y.; Lubet, R.; Steele, V.; Kelloff, G.; Paulson, S.; Seibert, K.; Rao, C.V. Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis. Cancer Res. 2000, 60, 293-297.
    • (2000) Cancer Res , vol.60 , pp. 293-297
    • Reddy, B.S.1    Hirose, Y.2    Lubet, R.3    Steele, V.4    Kelloff, G.5    Paulson, S.6    Seibert, K.7    Rao, C.V.8
  • 130
    • 0035866401 scopus 로고    scopus 로고
    • Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor
    • Oshima, M.; Murai, N.; Kargman, S.; Arguello, M.; Luk, P.; Kwong, E.; Taketo, M.M.; Evans, J.F. Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor. Cancer Res. 2001, 61, 1733-1740.
    • (2001) Cancer Res , vol.61 , pp. 1733-1740
    • Oshima, M.1    Murai, N.2    Kargman, S.3    Arguello, M.4    Luk, P.5    Kwong, E.6    Taketo, M.M.7    Evans, J.F.8
  • 131
    • 0034665122 scopus 로고    scopus 로고
    • The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis
    • Jacoby, R.F.; Seibert, K.; Cole, C.E.; Kelloff, G.; Lubet, R.A. The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis. Cancer Res. 2000, 60, 5040-5044.
    • (2000) Cancer Res , vol.60 , pp. 5040-5044
    • Jacoby, R.F.1    Seibert, K.2    Cole, C.E.3    Kelloff, G.4    Lubet, R.A.5
  • 133
    • 34249673868 scopus 로고    scopus 로고
    • Aspirin and the risk of colorectal cancer in relation to the expression of COX-2
    • Chan, A.T.; Ogino, S.; Fuchs, C.S. Aspirin and the risk of colorectal cancer in relation to the expression of COX-2. N. Engl. J. Med. 2007, 356, 2131-2142.
    • (2007) N. Engl. J. Med , vol.356 , pp. 2131-2142
    • Chan, A.T.1    Ogino, S.2    Fuchs, C.S.3
  • 135
    • 0142250380 scopus 로고    scopus 로고
    • A randomized, doubleblind, placebo-controlled trial of the effects of rofecoxib, a selective cyclooxygenase-2 inhibitor, on rectal polyps in familial adenomatous polyposis patients
    • Higuchi, T.; Iwama, T.; Yoshinaga, K.; Toyooka, M.; Taketo, M.M.; Sugihara, K. A randomized, doubleblind, placebo-controlled trial of the effects of rofecoxib, a selective cyclooxygenase-2 inhibitor, on rectal polyps in familial adenomatous polyposis patients. Clin. Cancer Res. 2003, 9, 4756-4760.
    • (2003) Clin. Cancer Res , vol.9 , pp. 4756-4760
    • Higuchi, T.1    Iwama, T.2    Yoshinaga, K.3    Toyooka, M.4    Taketo, M.M.5    Sugihara, K.6
  • 138
    • 68849123400 scopus 로고    scopus 로고
    • Aspirin use and survival after diagnosis of colorectal cancer
    • Chan, A.T.; Ogino, S.; Fuchs, C.S. Aspirin use and survival after diagnosis of colorectal cancer. JAMA 2009, 302, 649-658.
    • (2009) JAMA , vol.302 , pp. 649-658
    • Chan, A.T.1    Ogino, S.2    Fuchs, C.S.3
  • 141
    • 33645866160 scopus 로고    scopus 로고
    • Effects of cyclooxygenase-2 inhibition on serum and tumour gastrins and expression of apoptosis-related proteins in colorectal cancer
    • Konturek, P.C.; Rembiasz, K.; Burnat, G.; Konturek, S.J.; Tusinela, M.; Bielanski, W.; Rehfeld, J.; Karcz, D.; Hahn, E. Effects of cyclooxygenase-2 inhibition on serum and tumour gastrins and expression of apoptosis-related proteins in colorectal cancer. Dig. Dis. Sci. 2006, 51, 779-787.
    • (2006) Dig. Dis. Sci , vol.51 , pp. 779-787
    • Konturek, P.C.1    Rembiasz, K.2    Burnat, G.3    Konturek, S.J.4    Tusinela, M.5    Bielanski, W.6    Rehfeld, J.7    Karcz, D.8    Hahn, E.9
  • 142
    • 0038795405 scopus 로고    scopus 로고
    • Increased toxicity and lack of efficacy of Rofecoxib in combination with chemotherapy for treatment of metastatic colorectal cancer: A phase II study
    • Becerra, C.R.; Frenkel, E.P.; Ashfaq, R.; Gaynor, R.B. Increased toxicity and lack of efficacy of Rofecoxib in combination with chemotherapy for treatment of metastatic colorectal cancer: A phase II study. Int. J. Cancer 2003, 105, 868-872.
    • (2003) Int. J. Cancer , vol.105 , pp. 868-872
    • Becerra, C.R.1    Frenkel, E.P.2    Ashfaq, R.3    Gaynor, R.B.4


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