Irradiation-dependent effects on tumor perfusion and endogenous and exogenous hypoxia markers in an A549 xenograft model

International Journal of Radiation Oncology Biology Physics

Volumn 77, Issue 5, 2010, Pages 1500-1508

  Fokas, Emmanouil ^a   Hänze, Jörg ^b   Kamlah, Florentine ^a   Eul, Bastian G ^b   Lang, Nico ^b   Keil, Boris ^a   Heverhagen, Johannes T ^a   Engenhart Cabillic, Rita ^a   An, Hanxiang ^a   Rose, Frank ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

A549 xenograft; DCE MRI; hypoxia; Irradiation; perfusion

Indexed keywords

A549 XENOGRAFT; APOPTOSIS; CASPASE-3; CONTROL GROUPS; DCE-MRI; DYNAMIC CONTRAST-ENHANCED MAGNETIC RESONANCE IMAGING; HOECHST; HUMAN LUNG; HYPOXIA; HYPOXIA MARKER; HYPOXIC FRACTION; MICROVASCULAR; PERFUSION; REOXYGENATION; TIME POINTS; TUMOR MICROENVIRONMENT; TUMOR PERFUSION; TUMOR VESSELS; TUMOR VOLUMES; VASCULAR PERFUSION;

BIOLOGICAL MATERIALS; CELL DEATH; IONIZING RADIATION; IRRADIATION; RESONANCE; TUMORS;

MAGNETIC RESONANCE IMAGING;

1 (1,1,1,3,3,3 HEXAFLUORO 2 PROPOXY) 3 (2 NITRO 1 IMIDAZOLYL) 2 PROPANOL; CD31 ANTIGEN; GLUCOSE TRANSPORTER 1; HOE 33342; PIMONIDAZOLE; BENZIMIDAZOLE DERIVATIVE; BIOLOGICAL MARKER; CASPASE 3; CONTRAST MEDIUM; DIAGNOSTIC AGENT; GADOLINIUM; NITROIMIDAZOLE DERIVATIVE;

APOPTOSIS; ARTICLE; CELL STRAIN A549; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DOSE RESPONSE; GRAFT PERFUSION; HUMAN; HUMAN CELL; HYPOXIA; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE FRACTIONATION; TUMOR XENOGRAFT; ADENOCARCINOMA; ANIMAL; CELL HYPOXIA; FLUORESCENCE MICROSCOPY; IMMUNOLOGY; LUNG TUMOR; MALE; METABOLISM; METHODOLOGY; MOUSE; NUDE MOUSE; RADIATION EXPOSURE; TIME; VASCULARIZATION; XENOGRAFT;

ADENOCARCINOMA; ANIMALS; ANTIGENS, CD31; APOPTOSIS; BENZIMIDAZOLES; BIOLOGICAL MARKERS; CASPASE 3; CELL HYPOXIA; CONTRAST MEDIA; GADOLINIUM; GLUCOSE TRANSPORTER TYPE 1; HUMANS; LUNG NEOPLASMS; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE; NITROIMIDAZOLES; TIME FACTORS; TRANSPLANTATION, HETEROLOGOUS;

EID: 77955481726     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.01.060     Document Type: Article

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