Intravenous injection of siRNA directed against hypoxia-inducible factors prolongs survival in a Lewis lung carcinoma cancer model

Cancer Gene Therapy

Volumn 16, Issue 3, 2009, Pages 195-205

  Kamlah, F ^a   Eul, B G ^a   Li, S ^a   Lang, N ^a   Marsh, L M ^a   Seeger, W ^a   Grimminger, F ^a   Rose, F ^b   Hanze J ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Lung cancer; Mouse model; Orthotopic; Polyethylenimine; RNA interference

Indexed keywords

CD31 ANTIGEN; CYANINE DYE 3; FLUORESCENT DYE; GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; LIPOFECTAMINE; POLYETHYLENEIMINE; SMALL INTERFERING RNA; SMALL INTERFERING RNA CYANINE DYE 3 CONJUGATE; SMALL INTERFERING RNA CYANINE DYE 3 LIPOFECTAMINE CONJUGATE; SMALL INTERFERING RNA CYANINE DYE 3 POLYETHYLENEIMINE CONJUGATE; SMALL INTERFERING RNA LIPOFECTAMINE CONJUGATE; SMALL INTERFERING RNA POLYETHYLENEIMINE CONJUGATE; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER SURVIVAL; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; DOWN REGULATION; FLOW CYTOMETRY; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INHIBITION KINETICS; JUGULAR VEIN; LEWIS CARCINOMA; LUNG LAVAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARCINOMA, LEWIS LUNG; DOWN-REGULATION; GENE THERAPY; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMINES; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENOUS; JUGULAR VEINS; LIPIDS; LUNG NEOPLASMS; MICE; MICE, INBRED C57BL; NEOPLASM PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; POLYETHYLENES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SPECIFIC PATHOGEN-FREE ORGANISMS; SUBCUTANEOUS TISSUE; TRACHEA;

MUS;

EID: 60149093542     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/cgt.2008.71     Document Type: Article

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