메뉴 건너뛰기




Volumn 10, Issue 22, 2004, Pages 7712-7720

Application of a macromolecular contrast agent for detection of alterations of tumor vessel permeability induced by radiation

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; ANTINEOPLASTIC AGENT; CD31 ANTIGEN; CONTRAST MEDIUM; DENDRIMER; GADOLINIUM; MONOCLONAL ANTIBODY;

EID: 9344229794     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-04-1175     Document Type: Article
Times cited : (74)

References (62)
  • 2
    • 0030476061 scopus 로고    scopus 로고
    • Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma
    • Kimura H, Braun RD, Ong ET, et al. Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma. Cancer Res 1996;56:5522-8.
    • (1996) Cancer Res , vol.56 , pp. 5522-5528
    • Kimura, H.1    Braun, R.D.2    Ong, E.T.3
  • 3
    • 0033839080 scopus 로고    scopus 로고
    • Openings between defective endothelial cells explain tumor vessel leakiness
    • Hashizume H, Baluk P, Morikawa S, et al. Openings between defective endothelial cells explain tumor vessel leakiness. Am J Pathol 2000;156:1363-80.
    • (2000) Am J Pathol , vol.156 , pp. 1363-1380
    • Hashizume, H.1    Baluk, P.2    Morikawa, S.3
  • 4
    • 0034176782 scopus 로고    scopus 로고
    • Exploiting the hypoxic cancer cell: Mechanisms and therapeutic strategies
    • Brown JM. Exploiting the hypoxic cancer cell: mechanisms and therapeutic strategies. Mol Med Today 2000;6:157-62.
    • (2000) Mol Med Today , vol.6 , pp. 157-162
    • Brown, J.M.1
  • 5
    • 0037081174 scopus 로고    scopus 로고
    • Hemodynamics in vasculogenic mimicry and angiogenesis of inflammatory breast cancer xenograft
    • Shirakawa K, Kobayashi H, Heike Y, et al. Hemodynamics in vasculogenic mimicry and angiogenesis of inflammatory breast cancer xenograft. Cancer Res 2002;62:560-6.
    • (2002) Cancer Res , vol.62 , pp. 560-566
    • Shirakawa, K.1    Kobayashi, H.2    Heike, Y.3
  • 6
    • 0017705864 scopus 로고
    • Tumour vessel permeability and transcapillary exchange of large molecules of different size
    • Peterson HI, Appelgren L. Tumour vessel permeability and transcapillary exchange of large molecules of different size. Bibl Anat 1977;15: 262-5.
    • (1977) Bibl Anat , vol.15 , pp. 262-265
    • Peterson, H.I.1    Appelgren, L.2
  • 7
    • 0028470454 scopus 로고
    • Barriers to drug delivery in solid tumors
    • Jain RK. Barriers to drug delivery in solid tumors. Sci Am 1994; 271:58-65.
    • (1994) Sci Am , vol.271 , pp. 58-65
    • Jain, R.K.1
  • 8
    • 0042031680 scopus 로고    scopus 로고
    • Tumor microenvironment and the response to anticancer therapy
    • Brown JM. Tumor microenvironment and the response to anticancer therapy. Cancer Biol Ther 2002;1:453-8.
    • (2002) Cancer Biol Ther , vol.1 , pp. 453-458
    • Brown, J.M.1
  • 9
    • 0019349297 scopus 로고
    • Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells
    • Teicher BA, Lazo JS, Sartorelli AC. Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells. Cancer Res 1981;41:73-81.
    • (1981) Cancer Res , vol.41 , pp. 73-81
    • Teicher, B.A.1    Lazo, J.S.2    Sartorelli, A.C.3
  • 10
    • 0026684815 scopus 로고
    • Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms
    • Yokota T, Milenic DE, Whitlow M, Schlom J. Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms. Cancer Res 1992;52:3402-8.
    • (1992) Cancer Res , vol.52 , pp. 3402-3408
    • Yokota, T.1    Milenic, D.E.2    Whitlow, M.3    Schlom, J.4
  • 11
    • 0029114671 scopus 로고    scopus 로고
    • Targeting cancer micrometastases with monoclonal antibodies: A binding-site barrier
    • Saga T, Neumann RD, Heya T, et al. Targeting cancer micrometastases with monoclonal antibodies: A binding-site barrier. Proc Natl Acad Sci USA 1996;92:8999-9003.
    • (1996) Proc Natl Acad Sci USA , vol.92 , pp. 8999-9003
    • Saga, T.1    Neumann, R.D.2    Heya, T.3
  • 12
    • 0015396778 scopus 로고
    • Effect of irradiation on tumor microvascualture permeability to macro molecules
    • Potchen EJ, Kinzie J, Curtis C, Siegal BA, Studer RK. Effect of irradiation on tumor microvascualture permeability to macro molecules. Cancer (Phila) 1972;30:639-42.
    • (1972) Cancer (Phila) , vol.30 , pp. 639-642
    • Potchen, E.J.1    Kinzie, J.2    Curtis, C.3    Siegal, B.A.4    Studer, R.K.5
  • 13
    • 0013963522 scopus 로고
    • Microcirculation of tumors: The supervascualized state of irradiated regressing tumors
    • Rubin P, Casarett G. Microcirculation of tumors: the supervascualized state of irradiated regressing tumors. Clin Radiol 1966;17:346-55.
    • (1966) Clin Radiol , vol.17 , pp. 346-355
    • Rubin, P.1    Casarett, G.2
  • 14
    • 0015100428 scopus 로고
    • Vascular changes in Walker 256 carcinoma of rats following × irradiation
    • Song CW, Levitt SH. Vascular changes in Walker 256 carcinoma of rats following × irradiation. Radiobiol 1971;100:397-407.
    • (1971) Radiobiol , vol.100 , pp. 397-407
    • Song, C.W.1    Levitt, S.H.2
  • 16
    • 9344249801 scopus 로고
    • Enhancement of monoclonal antibody (Mab) binding to melanoma with single dose radiation or hyperthermia
    • Stickney DR, Gridley DS, Kirk GA, Slater JM. Enhancement of monoclonal antibody (Mab) binding to melanoma with single dose radiation or hyperthermia. Cancer Drug Del 1985;2:225.
    • (1985) Cancer Drug Del , vol.2 , pp. 225
    • Stickney, D.R.1    Gridley, D.S.2    Kirk, G.A.3    Slater, J.M.4
  • 17
    • 0030901552 scopus 로고    scopus 로고
    • Timing effects of combined radioimmunotherapy and radiotherapy on a human solid tumor in nude mice
    • Sun LQ, Vogel CA, Mirimanoff RO, et al. Timing effects of combined radioimmunotherapy and radiotherapy on a human solid tumor in nude mice. Cancer Res 1997;57:1312-9.
    • (1997) Cancer Res , vol.57 , pp. 1312-1319
    • Sun, L.Q.1    Vogel, C.A.2    Mirimanoff, R.O.3
  • 18
    • 0033767350 scopus 로고    scopus 로고
    • Optimizing the sequence of combination therapy with radiolabeled antibodies and fractionated external beam
    • Ruan S, O'Donoghue JA, Larson SM, et al. Optimizing the sequence of combination therapy with radiolabeled antibodies and fractionated external beam. J Nucl Med 2000;41:1905-12.
    • (2000) J Nucl Med , vol.41 , pp. 1905-1912
    • Ruan, S.1    O'Donoghue, J.A.2    Larson, S.M.3
  • 19
    • 0028937470 scopus 로고
    • Radiolabeled antibody combined with external radiotherapy for the treatment of head and neck cancer: Reconstruction of a theoretical phantom for the larynx for radiation dose calculation to local tissues
    • Maraveyas A, Myers M, Stafford N, Rowlinson-Busza G, Stewart JS, Epenetos AA. Radiolabeled antibody combined with external radiotherapy for the treatment of head and neck cancer: reconstruction of a theoretical phantom for the larynx for radiation dose calculation to local tissues. Cancer Res 1995;55:1020-7.
    • (1995) Cancer Res , vol.55 , pp. 1020-1027
    • Maraveyas, A.1    Myers, M.2    Stafford, N.3    Rowlinson-Busza, G.4    Stewart, J.S.5    Epenetos, A.A.6
  • 20
    • 0037083372 scopus 로고    scopus 로고
    • The combination of external beam radiotherapy and experimental radioimmunotargeting with a monoclonal anticytokeratin antibody
    • Johansson A, Eriksson D, Ullen A, et al. The combination of external beam radiotherapy and experimental radioimmunotargeting with a monoclonal anticytokeratin antibody. Cancer (Phila) 2002;94: 1314-9.
    • (2002) Cancer (Phila) , vol.94 , pp. 1314-1319
    • Johansson, A.1    Eriksson, D.2    Ullen, A.3
  • 21
    • 0035105015 scopus 로고    scopus 로고
    • 3D-micro-MR angiography of mice using macromolecular MR contrast agents with polyamidoamine dendrimer core with references to their pharmacokinetic properties
    • Kobayashi H, Sato N, Hiraga A, et al. 3D-micro-MR angiography of mice using macromolecular MR contrast agents with polyamidoamine dendrimer core with references to their pharmacokinetic properties. Magn Reson Med 2001;45:454-60.
    • (2001) Magn Reson Med , vol.45 , pp. 454-460
    • Kobayashi, H.1    Sato, N.2    Hiraga, A.3
  • 22
    • 0035191513 scopus 로고    scopus 로고
    • Micro-MR angiography of normal and intratumoral vessels in mice using dedicated intravascular MR contrast agents with high generation of polyamidoamine dendrimer core: Reference to pharmacokinetic properties of dendrimer-based MR contrast agents
    • Kobayashi H, Kawamoto S, Saga T, et al. Micro-MR angiography of normal and intratumoral vessels in mice using dedicated intravascular MR contrast agents with high generation of polyamidoamine dendrimer core: reference to pharmacokinetic properties of dendrimer-based MR contrast agents. J Magn Reson Imaging 2001;14:705-13.
    • (2001) J Magn Reson Imaging , vol.14 , pp. 705-713
    • Kobayashi, H.1    Kawamoto, S.2    Saga, T.3
  • 23
    • 0038641304 scopus 로고    scopus 로고
    • Gadolinium-labeled dendrimers as biometric nanoprobes to detect vascular permeability
    • Yordanov AT, Kobayashi H, English SJ, et al. Gadolinium-labeled dendrimers as biometric nanoprobes to detect vascular permeability J Mater Chem 2003;13:1523-5.
    • (2003) J Mater Chem , vol.13 , pp. 1523-1525
    • Yordanov, A.T.1    Kobayashi, H.2    English, S.J.3
  • 24
    • 0025373701 scopus 로고
    • Starburst dendrimers: Molecular-level control of size, shape, surface chemistry, topology, and flexibility from atoms to macroscopic matter
    • Tomalia DA, Naylor AM, Goddard III WA. Starburst dendrimers: Molecular-level control of size, shape, surface chemistry, topology, and flexibility from atoms to macroscopic matter. Angew Chem Int Ed Engl 1990;29:138-75.
    • (1990) Angew Chem Int Ed Engl , vol.29 , pp. 138-175
    • Tomalia, D.A.1    Naylor, A.M.2    Goddard III, W.A.3
  • 25
    • 0034005436 scopus 로고    scopus 로고
    • Dendrimers: Relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 1251-labelled polyamidoamine dendrimers in vivo
    • Malik N, Wiwattanapatapee R, Klopsch R, et al. Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 1251-labelled polyamidoamine dendrimers in vivo. J Control Release 2000;65:133-48.
    • (2000) J Control Release , vol.65 , pp. 133-148
    • Malik, N.1    Wiwattanapatapee, R.2    Klopsch, R.3
  • 26
    • 0034794601 scopus 로고    scopus 로고
    • Novel liver macromolecular MR contrast agent with a polypropylenimine diaminobutyl dendrimer core: Comparison to the vascular MR contrast agent with the polyamidoamine dendrimer core
    • Kobayashi H, Kawamoto S, Saga T, et al. Novel liver macromolecular MR contrast agent with a polypropylenimine diaminobutyl dendrimer core: comparison to the vascular MR contrast agent with the polyamidoamine dendrimer core Magn Reson Med 2001;46:795-802.
    • (2001) Magn Reson Med , vol.46 , pp. 795-802
    • Kobayashi, H.1    Kawamoto, S.2    Saga, T.3
  • 27
    • 0028267412 scopus 로고
    • Metal-chelate-dendrimer-antibody constructs for use in radioimmunotherapy and imaging
    • Wu C, Brechbiel MW, Kozak RW, Gansow OA. Metal-chelate-dendrimer-antibody constructs for use in radioimmunotherapy and imaging. Bioorg Med Chem Lett 1994;4:449-54.
    • (1994) Bioorg Med Chem Lett , vol.4 , pp. 449-454
    • Wu, C.1    Brechbiel, M.W.2    Kozak, R.W.3    Gansow, O.A.4
  • 28
    • 0028168360 scopus 로고
    • Starburst dendrimers: Enhanced performance and flexibility for immunoassays
    • Singh P, Moll III F, Lin SH, et al. Starburst dendrimers: enhanced performance and flexibility for immunoassays. Clin Chem 1994;40: 1845-9.
    • (1994) Clin Chem , vol.40 , pp. 1845-1849
    • Singh, P.1    Moll III, F.2    Lin, S.H.3
  • 29
    • 0027950222 scopus 로고
    • Boronated starburst dendrimer-monoclonal antibody immunoconjugates: Evaluation as a potential delivery system for neutron capture therapy
    • Barth RF, Adams DM, Soloway AH, Alam F, Darby MV. Boronated starburst dendrimer-monoclonal antibody immunoconjugates: evaluation as a potential delivery system for neutron capture therapy. Bioconjug Chem 1994;5:58-66.
    • (1994) Bioconjug Chem , vol.5 , pp. 58-66
    • Barth, R.F.1    Adams, D.M.2    Soloway, A.H.3    Alam, F.4    Darby, M.V.5
  • 30
    • 0032892747 scopus 로고    scopus 로고
    • Evaluation of the in vivo biodistribution of indium-111 and yttrium-88 labeled dendrimer-1B4M-DTPA and its conjugation with anti-Tac monoclonal antibody
    • Kobayashi H, Wu C, Kim MK, Paik CH, Carrasquillo JA, Brechbiel MW. Evaluation of the in vivo biodistribution of indium-111 and yttrium-88 labeled dendrimer-1B4M-DTPA and its conjugation with anti-Tac monoclonal antibody. Bioconjug Chem 1999;10:103-11.
    • (1999) Bioconjug Chem , vol.10 , pp. 103-111
    • Kobayashi, H.1    Wu, C.2    Kim, M.K.3    Paik, C.H.4    Carrasquillo, J.A.5    Brechbiel, M.W.6
  • 31
    • 0033866567 scopus 로고    scopus 로고
    • Monoclonal antibody-dendrimer conjugates enable radiolabeling of antibody with markedly high specific activity with minimal loss of immunoreactivity
    • Kobayashi H, Sato N, Saga T, et al. Monoclonal antibody-dendrimer conjugates enable radiolabeling of antibody with markedly high specific activity with minimal loss of immunoreactivity. Eur J Nucl Med 2000;27:1334-9.
    • (2000) Eur J Nucl Med , vol.27 , pp. 1334-1339
    • Kobayashi, H.1    Sato, N.2    Saga, T.3
  • 32
    • 0033860453 scopus 로고    scopus 로고
    • MRI characterization of tumors and grading angiogenesis using macromolecular contrast media: Status report
    • Brasch R, Turetschek K. MRI characterization of tumors and grading angiogenesis using macromolecular contrast media: status report. Eur J Radiol 2000;34:148-55.
    • (2000) Eur J Radiol , vol.34 , pp. 148-155
    • Brasch, R.1    Turetschek, K.2
  • 33
    • 0031421953 scopus 로고    scopus 로고
    • Assessing tumor angiogenesis using macromolecular MR imaging contrast media
    • Brasch R, Pham C, Shames D, et al. Assessing tumor angiogenesis using macromolecular MR imaging contrast media. J Magn Reson Imaging 1997;7:68-74.
    • (1997) J Magn Reson Imaging , vol.7 , pp. 68-74
    • Brasch, R.1    Pham, C.2    Shames, D.3
  • 34
    • 0036163583 scopus 로고    scopus 로고
    • Assessment of the neovasculature permeability in glioma xenografts by dynamic T1 MRI with gadomer-17
    • Verhoye M, van der Sanden BPJ, Rijken PFJW, et al. Assessment of the neovasculature permeability in glioma xenografts by dynamic T1 MRI with gadomer-17. Magn Reson Med 2002;47:305-13.
    • (2002) Magn Reson Med , vol.47 , pp. 305-313
    • Verhoye, M.1    Van Der Sanden, B.P.J.2    Rijken, P.F.J.W.3
  • 36
    • 0023853045 scopus 로고
    • Plasma and tumor concentrations of cisplatin following intraperitoneal infusion or bolus injection with or without continuous low-dose-rate irradiation
    • Fu KK, DeGregorio MW, Phillips JW. Plasma and tumor concentrations of cisplatin following intraperitoneal infusion or bolus injection with or without continuous low-dose-rate irradiation. NCI Monogr 1988;6:123-7.
    • (1988) NCI Monogr , vol.6 , pp. 123-127
    • Fu, K.K.1    DeGregorio, M.W.2    Phillips, J.W.3
  • 37
    • 0031903379 scopus 로고    scopus 로고
    • Transvascular drug delivery in solid tumors
    • Yuan F. Transvascular drug delivery in solid tumors. Semin Radiat Oncol 1998;8:164-75.
    • (1998) Semin Radiat Oncol , vol.8 , pp. 164-175
    • Yuan, F.1
  • 38
    • 0023788067 scopus 로고
    • Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules
    • Dvorak HF, Nagy JA, Dvorak JT, Dvorak AM. Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules. Am J Pathol 1988;133:95-109.
    • (1988) Am J Pathol , vol.133 , pp. 95-109
    • Dvorak, H.F.1    Nagy, J.A.2    Dvorak, J.T.3    Dvorak, A.M.4
  • 39
    • 0023219734 scopus 로고
    • Transport of molecules in the tumor interstitium: A review
    • Jain RK. Transport of molecules in the tumor interstitium: a review. Cancer Res 1987;47:3039-51.
    • (1987) Cancer Res , vol.47 , pp. 3039-3051
    • Jain, R.K.1
  • 40
    • 0036071403 scopus 로고    scopus 로고
    • Advances in animal PET scanners
    • Del Guerra A, Belcari N. Advances in animal PET scanners. Q J Nucl Med 2002;46:35-47.
    • (2002) Q J Nucl Med , vol.46 , pp. 35-47
    • Del Guerra, A.1    Belcari, N.2
  • 41
    • 0034840078 scopus 로고    scopus 로고
    • 3D MR angiography of intratumoral vasculature using a macromolecular MR contrast agent
    • Kobayashi H, Sato N, Kawamoto S, et al. 3D MR angiography of intratumoral vasculature using a macromolecular MR contrast agent. Magn Reson Med 2001;46:579-85.
    • (2001) Magn Reson Med , vol.46 , pp. 579-585
    • Kobayashi, H.1    Sato, N.2    Kawamoto, S.3
  • 42
  • 43
    • 0036326017 scopus 로고    scopus 로고
    • In vivo magnetic resonance tracking of magnetically labeled cells after transplantation
    • Bulte JW, Duncan ID, Frank J. A. In vivo magnetic resonance tracking of magnetically labeled cells after transplantation. J Cereb Blood Flow Metab 2002;22:899-907.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 899-907
    • Bulte, J.W.1    Duncan, I.D.2    Frank, J.A.3
  • 44
    • 0028584431 scopus 로고
    • Contrast-enhanced magnetic resonance imaging estimation of altered capillary permeability in experimental mammary carcinomas after X-irradiation
    • Cohen FM, Kuwatsuru R, Shames DM, et al. Contrast-enhanced magnetic resonance imaging estimation of altered capillary permeability in experimental mammary carcinomas after X-irradiation. Invest Radiol 1994;29:970-7.
    • (1994) Invest Radiol , vol.29 , pp. 970-977
    • Cohen, F.M.1    Kuwatsuru, R.2    Shames, D.M.3
  • 45
    • 0036022341 scopus 로고    scopus 로고
    • A longitudinal study of radiation-induced changes in tumor vasculature by contrast-enhanced magnetic resonance imaging
    • Yu H, Su MY, Wang Z, Nalcioglu O. A longitudinal study of radiation-induced changes in tumor vasculature by contrast-enhanced magnetic resonance imaging. Rad Res 2002;158:152-8.
    • (2002) Rad Res , vol.158 , pp. 152-158
    • Yu, H.1    Su, M.Y.2    Wang, Z.3    Nalcioglu, O.4
  • 46
    • 0003131542 scopus 로고    scopus 로고
    • Repair of radiation damage and the dose-rate effect
    • EJ. Hall (editor). Philadelphia, PA: Lippincott Williams & Wilkins
    • Hall EJ. Repair of radiation damage and the dose-rate effect. In: EJ. Hall (editor) Radiobiology for the radiologist. Philadelphia, PA: Lippincott Williams & Wilkins, 2000. pp. 67-90.
    • (2000) Radiobiology for the Radiologist , pp. 67-90
    • Hall, E.J.1
  • 47
    • 0032516078 scopus 로고    scopus 로고
    • Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment
    • Hobbs SK, Monsky WL, Yuan F, et al. Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proc Natl Acad Sci USA 1998;95:4607-12.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 4607-4612
    • Hobbs, S.K.1    Monsky, W.L.2    Yuan, F.3
  • 48
    • 0034662609 scopus 로고    scopus 로고
    • Hyperthermia enables tumor-specific nanoparticle delivery: Effect of particle size
    • Kong G, Braun RD, Dewhirst MW. Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size. Cancer Res 2000; 60:4440-5.
    • (2000) Cancer Res , vol.60 , pp. 4440-4445
    • Kong, G.1    Braun, R.D.2    Dewhirst, M.W.3
  • 49
    • 0028304405 scopus 로고
    • Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft
    • Yuan F, Leunig M, Huang SK, Berk DA, Papahadjopoulos D, Jain RK. Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft. Cancer Res 1994;54:3352-6.
    • (1994) Cancer Res , vol.54 , pp. 3352-3356
    • Yuan, F.1    Leunig, M.2    Huang, S.K.3    Berk, D.A.4    Papahadjopoulos, D.5    Jain, R.K.6
  • 50
    • 0022946258 scopus 로고
    • In vitro and in vivo tumor models for studies of distribution of radiolabelled monoclonal antibodies and fragments
    • Buchegger F, Halpern SE, Sutherland RM, Schreyer M, Mach JP. In vitro and in vivo tumor models for studies of distribution of radiolabelled monoclonal antibodies and fragments, Nuklearmedizin 1986;25: 207-9.
    • (1986) Nuklearmedizin , vol.25 , pp. 207-209
    • Buchegger, F.1    Halpern, S.E.2    Sutherland, R.M.3    Schreyer, M.4    Mach, J.P.5
  • 51
    • 0033555629 scopus 로고    scopus 로고
    • The pharmacokinetic characteristics of glycolated humanized anti-Tac Fabs are determined by their isoelectric points
    • Kobayashi H, Le N, Kim IS, et al. The pharmacokinetic characteristics of glycolated humanized anti-Tac Fabs are determined by their isoelectric points. Cancer Res 1999;59:422-30.
    • (1999) Cancer Res , vol.59 , pp. 422-430
    • Kobayashi, H.1    Le, N.2    Kim, I.S.3
  • 53
    • 0029890636 scopus 로고    scopus 로고
    • Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts
    • Hu S, Shively L, Raubitschek A, et al. Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts. Cancer Res 1996;56:3055-61.
    • (1996) Cancer Res , vol.56 , pp. 3055-3061
    • Hu, S.1    Shively, L.2    Raubitschek, A.3
  • 55
    • 0027303686 scopus 로고
    • Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-cerbB-2 single-chain Fv
    • Adams GP, McCartney JE, Tai MS, et al. Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-cerbB-2 single-chain Fv. Cancer Res 1993;53:4026-34.
    • (1993) Cancer Res , vol.53 , pp. 4026-4034
    • Adams, G.P.1    McCartney, J.E.2    Tai, M.S.3
  • 56
    • 0038626211 scopus 로고    scopus 로고
    • Tumor response to radiotherapy regulated by endothelial cell apoptosis
    • Garcia-Barros M, Paris F, Cordon-Cardo C, et al. Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science (Wash DC) 2003;300:1155-9.
    • (2003) Science (Wash DC) , vol.300 , pp. 1155-1159
    • Garcia-Barros, M.1    Paris, F.2    Cordon-Cardo, C.3
  • 57
    • 0037529332 scopus 로고    scopus 로고
    • Multistep nature of microvascular recruitment of ex vivo-expanded embryonic endothelial progenitor cells during tumor angiogenesis
    • Vajkoczy P, Blum S, Lamparter M, et al. Multistep nature of microvascular recruitment of ex vivo-expanded embryonic endothelial progenitor cells during tumor angiogenesis. J Exp Med 2003;197: 1755-65.
    • (2003) J Exp Med , vol.197 , pp. 1755-1765
    • Vajkoczy, P.1    Blum, S.2    Lamparter, M.3
  • 58
    • 0028208015 scopus 로고
    • Differences in leucocyte-endothelium interactions between normal and adenocarcinoma bearing tissues in response to radiation
    • Wu NZ, Ross BA, Gulledge C, Klitzman B, Dodge R, Dewhirst MW. Differences in leucocyte-endothelium interactions between normal and adenocarcinoma bearing tissues in response to radiation. Br J Cancer 1994:69:883-9.
    • (1994) Br J Cancer , vol.69 , pp. 883-889
    • Wu, N.Z.1    Ross, B.A.2    Gulledge, C.3    Klitzman, B.4    Dodge, R.5    Dewhirst, M.W.6
  • 59
    • 0038278831 scopus 로고    scopus 로고
    • Identification of a protein fragment of interleukin 2 responsible for vasopermeability
    • Epstein AL, Mizokami MM, Li J, Hu P, Khawli LA. Identification of a protein fragment of interleukin 2 responsible for vasopermeability. J Natl Cancer Inst 2003;95:741-9.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 741-749
    • Epstein, A.L.1    Mizokami, M.M.2    Li, J.3    Hu, P.4    Khawli, L.A.5
  • 60
    • 0036842215 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor: A critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy
    • Dvorak HF. Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J Clin Oncol 2002;20:4368-80.
    • (2002) J Clin Oncol , vol.20 , pp. 4368-4380
    • Dvorak, H.F.1
  • 61
    • 0033564974 scopus 로고    scopus 로고
    • Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation
    • Gorski DH, Beckett MA, Jaskowiak NT, et al. Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation. Cancer Res 1999;59:3374-8.
    • (1999) Cancer Res , vol.59 , pp. 3374-3378
    • Gorski, D.H.1    Beckett, M.A.2    Jaskowiak, N.T.3
  • 62
    • 0030022119 scopus 로고    scopus 로고
    • Effect of radiation on interstitial fluid pressure and oxygenation in a human tumor xenograft
    • Znati CA, Rosenstein M, Boucher Y, Epperly MW, Bloomer WD, Jain RK. Effect of radiation on interstitial fluid pressure and oxygenation in a human tumor xenograft. Cancer Res 1996;56:964-8.
    • (1996) Cancer Res , vol.56 , pp. 964-968
    • Znati, C.A.1    Rosenstein, M.2    Boucher, Y.3    Epperly, M.W.4    Bloomer, W.D.5    Jain, R.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.