Nonpeptidic vinyl and allyl phosphonates as falcipain-2 inhibitors

ChemMedChem

Volumn 3, Issue 7, 2008, Pages 1030-1033

  Ettari, Roberta ^a   Nizi, Emanuela ^b   Di Francesco, Maria Emilia ^b   Micale, Nicola ^a   Grasso, Silvana ^a   Zappalà, Maria ^a   Vičík, Radim ^c   Schirmeister, Tanja ^c  

^a UNIVERSITY OF MESSINA   (Italy)

^b IRBM   (Italy)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Cysteine proteases; Falcipain 2 inhibitors; Michael acceptors; Vinyl phosphonates

Indexed keywords

BENZODIAZEPINE DERIVATIVE; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; DIVINYL SULFONE; FALCIPAIN 2; PHOSPHONIC ACID DERIVATIVE; SULFONE;

ANIMAL; ARTICLE; CHEMICAL MODEL; CHEMISTRY; DRUG EFFECT; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; BENZODIAZEPINES; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; MODELS, CHEMICAL; PHOSPHONIC ACIDS; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONES;

EID: 54849203300     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200800050     Document Type: Article

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