-
1
-
-
0031001720
-
Alternative projections of mortality and disability by cause 1990-2020: global burden of disease study
-
Murray C.J., Lopez A.D. Alternative projections of mortality and disability by cause 1990-2020: global burden of disease study. Lancet 1997, 349:1498-1504.
-
(1997)
Lancet
, vol.349
, pp. 1498-1504
-
-
Murray, C.J.1
Lopez, A.D.2
-
2
-
-
0141741729
-
Estimates of Global mortality attributable to smoking in 2000
-
Essata M., Lopez A.D. Estimates of Global mortality attributable to smoking in 2000. Lancet 2003, 362:847-852.
-
(2003)
Lancet
, vol.362
, pp. 847-852
-
-
Essata, M.1
Lopez, A.D.2
-
4
-
-
38849185354
-
Definition, epidemiology and natural history of COPD
-
Vigel G., Pistelli F., Sherill D.L., Maio S., Baldacci S., Carrozzi L. Definition, epidemiology and natural history of COPD. Eur Resp J 2007, 30:993-1010.
-
(2007)
Eur Resp J
, vol.30
, pp. 993-1010
-
-
Vigel, G.1
Pistelli, F.2
Sherill, D.L.3
Maio, S.4
Baldacci, S.5
Carrozzi, L.6
-
6
-
-
53649093994
-
Recent advances in exacerbations of COPD
-
ICEAD contributors
-
Seemungal T., Sykes A. Recent advances in exacerbations of COPD. Thorax 2008, 63:850-852. ICEAD contributors.
-
(2008)
Thorax
, vol.63
, pp. 850-852
-
-
Seemungal, T.1
Sykes, A.2
-
7
-
-
0037373003
-
The burden of COPD in the USA: results from the confronting COPD survey
-
Halpern M.T., Stanford R.H., Borker R. The burden of COPD in the USA: results from the confronting COPD survey. Respir Med 2003, 97(Suppl. C):s81-s89.
-
(2003)
Respir Med
, vol.97
, Issue.SUPPL. C
-
-
Halpern, M.T.1
Stanford, R.H.2
Borker, R.3
-
8
-
-
77955429717
-
Yoshida & Tuder. Pathobiology of cigarette smoke induced chronic pulmonary disease
-
Yoshida & Tuder. Pathobiology of cigarette smoke induced chronic pulmonary disease. Physiol Review (2).
-
Physiol Review
, vol.2
-
-
-
9
-
-
51649091911
-
The many " small COPDs": COPD should be an orphan disease
-
007; 87:1047-82
-
Rennard S.I., Vestbo J. The many " small COPDs": COPD should be an orphan disease. Chest 2008, 134:623-627. 007; 87:1047-82.
-
(2008)
Chest
, vol.134
, pp. 623-627
-
-
Rennard, S.I.1
Vestbo, J.2
-
10
-
-
1042269503
-
Innate immunity in the lung: how epithelial cells fight against respiratory pathogens
-
Bals R., Hiemstra P.S. Innate immunity in the lung: how epithelial cells fight against respiratory pathogens. Eur Respir J 2004, 23:327-333.
-
(2004)
Eur Respir J
, vol.23
, pp. 327-333
-
-
Bals, R.1
Hiemstra, P.S.2
-
12
-
-
70349129549
-
Accelerated lung aging: a novel pathogenic mechanism of COPD
-
MacNee W. Accelerated lung aging: a novel pathogenic mechanism of COPD. Biochem Soc Trans 2009, 37:819-823.
-
(2009)
Biochem Soc Trans
, vol.37
, pp. 819-823
-
-
MacNee, W.1
-
13
-
-
13944262937
-
Understanding the odd science of aging
-
Kirkwood T.B.L. Understanding the odd science of aging. Cell 2005, 120:437-447.
-
(2005)
Cell
, vol.120
, pp. 437-447
-
-
Kirkwood, T.B.L.1
-
14
-
-
0036729605
-
Chronic obstructive pulmonary disease (c2): pathology and biochemistry of emphysema
-
Hogg J.C., Senior R.M. Chronic obstructive pulmonary disease (c2): pathology and biochemistry of emphysema. Thorax 2002, 57:830-834.
-
(2002)
Thorax
, vol.57
, pp. 830-834
-
-
Hogg, J.C.1
Senior, R.M.2
-
15
-
-
13144252260
-
Tobacco smoke is a source of toxic reactive glycation products
-
Cerami C., Founds I., Nicholl I., Mitsuhashi T., Giorano D., Vanpatten S., et al. Tobacco smoke is a source of toxic reactive glycation products. Proc Natl Acad Sci 1997, 1997(94):13915-13920.
-
(1997)
Proc Natl Acad Sci
, vol.1997
, Issue.94
, pp. 13915-13920
-
-
Cerami, C.1
Founds, I.2
Nicholl, I.3
Mitsuhashi, T.4
Giorano, D.5
Vanpatten, S.6
-
16
-
-
61649084651
-
Cough and viruses in airways disease: mechanisms
-
Footitt J., Johnston S.L. Cough and viruses in airways disease: mechanisms. Pulm Pharmacol Ther 2009, 22(2):108-113.
-
(2009)
Pulm Pharmacol Ther
, vol.22
, Issue.2
, pp. 108-113
-
-
Footitt, J.1
Johnston, S.L.2
-
17
-
-
6944222804
-
Comphrehensive gene expression profiles reveal pathways related to the pathogenesis of a chronic obstructive pulmonary disease
-
Ning W., Li C.J., Kaminski N., Feghali-Bostwick C.A., Alber S.M., Di Y.P., et al. Comphrehensive gene expression profiles reveal pathways related to the pathogenesis of a chronic obstructive pulmonary disease. Proc Natl Acad Sci 2004, 101:14895-14900.
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 14895-14900
-
-
Ning, W.1
Li, C.J.2
Kaminski, N.3
Feghali-Bostwick, C.A.4
Alber, S.M.5
Di, Y.P.6
-
18
-
-
33947326921
-
Expression of genes involved in oxidative stress responses in airway epithelial cells of smokers with chronic obstructive pulmonary disease
-
Pierrou S., Broberg P., O'Donnell R.A., Pawłowski K., Virtala R., Lindqvist E., et al. Expression of genes involved in oxidative stress responses in airway epithelial cells of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007, 175(6):577-586.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, Issue.6
, pp. 577-586
-
-
Pierrou, S.1
Broberg, P.2
O'Donnell, R.A.3
Pawłowski, K.4
Virtala, R.5
Lindqvist, E.6
-
19
-
-
39849096188
-
Gene expression profiling in patients with chronic obstructive pulmonary disease and lung cancer
-
Wang I.M., Stepaniants S., Boie Y., Mortimer J.R., Kennedy B., Elliot M., et al. Gene expression profiling in patients with chronic obstructive pulmonary disease and lung cancer. Am J Resp Crit Care Med 2008, 177:402-411.
-
(2008)
Am J Resp Crit Care Med
, vol.177
, pp. 402-411
-
-
Wang, I.M.1
Stepaniants, S.2
Boie, Y.3
Mortimer, J.R.4
Kennedy, B.5
Elliot, M.6
-
20
-
-
42949118737
-
Cigarette smoke induces an unfolded protein response in the human lung
-
Kelsen S., Duan X., Ji R., Perez O., Liu C., Merali S. Cigarette smoke induces an unfolded protein response in the human lung. Am J Resp Cell Mol Biol 2008, 38:541-550.
-
(2008)
Am J Resp Cell Mol Biol
, vol.38
, pp. 541-550
-
-
Kelsen, S.1
Duan, X.2
Ji, R.3
Perez, O.4
Liu, C.5
Merali, S.6
-
22
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
Dostert C., Pétrilli V., Van Bruggen R., Steele C., Mossman B.T., Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 2008, 320:674-677.
-
(2008)
Science
, vol.320
, pp. 674-677
-
-
Dostert, C.1
Pétrilli, V.2
Van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
23
-
-
33745728358
-
Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications of histone deacetylase in macrophages
-
Yang S.R., Chida A.S., Bauter M.R., Shafiq N., Seweryniak K., Maggirwar S.B., et al. Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications of histone deacetylase in macrophages. Am J Physiol Lung Cell Mol Physiol 2006, 291:L46-L57.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
-
-
Yang, S.R.1
Chida, A.S.2
Bauter, M.R.3
Shafiq, N.4
Seweryniak, K.5
Maggirwar, S.B.6
-
24
-
-
33750949369
-
Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells
-
Kode A., Yang S.R., Rahman I. Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells. Resp Res 2006, 7:132.
-
(2006)
Resp Res
, vol.7
, pp. 132
-
-
Kode, A.1
Yang, S.R.2
Rahman, I.3
-
25
-
-
15244356847
-
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice
-
Rangasamy T., Cho C.Y., Thimmulappa R.K., Zhen L., Srisuma S.S., Kensler T.W., et al. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest 2004, 114:1248-1259.
-
(2004)
J Clin Invest
, vol.114
, pp. 1248-1259
-
-
Rangasamy, T.1
Cho, C.Y.2
Thimmulappa, R.K.3
Zhen, L.4
Srisuma, S.S.5
Kensler, T.W.6
-
26
-
-
58549105575
-
Targeting NFR2 with the triterpenoid CDDO-imidazole attenuates cigarette smoke-induced emphysema and cardiac function in mice
-
Sussan T.E., Rangasamy T., Blake D.J., Malhotra D., El-Haddad H., Bedja D., et al. Targeting NFR2 with the triterpenoid CDDO-imidazole attenuates cigarette smoke-induced emphysema and cardiac function in mice. Proc Natl Acad Sci 2009, 106:250-255.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 250-255
-
-
Sussan, T.E.1
Rangasamy, T.2
Blake, D.J.3
Malhotra, D.4
El-Haddad, H.5
Bedja, D.6
-
27
-
-
76149105697
-
Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation
-
June 11th
-
Blake D.J., Singh A., Kombairaju P., Malhotra D., Mariani T.J., Tuder R.M., et al. Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation. Am J Resp Cell Mol Biol 2009, June 11th.
-
(2009)
Am J Resp Cell Mol Biol
-
-
Blake, D.J.1
Singh, A.2
Kombairaju, P.3
Malhotra, D.4
Mariani, T.J.5
Tuder, R.M.6
-
28
-
-
60549100921
-
Suppression of pulmonary innate host defense in smokers
-
Bals R for the CAPNETZ study group
-
Herr C., Beisswenger C., Hess C., Kandler K., Suttorp N., Welte T., et al. Suppression of pulmonary innate host defense in smokers. Thorax 2008, 64:144-149. Bals R for the CAPNETZ study group.
-
(2008)
Thorax
, vol.64
, pp. 144-149
-
-
Herr, C.1
Beisswenger, C.2
Hess, C.3
Kandler, K.4
Suttorp, N.5
Welte, T.6
-
29
-
-
0033452745
-
Defensins:key players or bystanders in infection, injury and repair in the lung?
-
Van Wetering S., Sterk P.J., Rabe K.F., Hiemstra P.S. Defensins:key players or bystanders in infection, injury and repair in the lung?. J Allergy Clin Immunnol 1999, 104:1131-1138.
-
(1999)
J Allergy Clin Immunnol
, vol.104
, pp. 1131-1138
-
-
Van Wetering, S.1
Sterk, P.J.2
Rabe, K.F.3
Hiemstra, P.S.4
-
30
-
-
0035094928
-
Pulmonary collectins and innate host defense of the lung
-
LeVine A.M., Whisett J.A. Pulmonary collectins and innate host defense of the lung. Microbes Infect 2001, 3:161-166.
-
(2001)
Microbes Infect
, vol.3
, pp. 161-166
-
-
LeVine, A.M.1
Whisett, J.A.2
-
31
-
-
33645982232
-
Human neutrophil elastase inhibitors in innate and adaptive immunity
-
Fitch P.M., Roghanian A., Howie S.E., Sallenave J.M. Human neutrophil elastase inhibitors in innate and adaptive immunity. Biochem Soc Trans 2006, 34:279-282.
-
(2006)
Biochem Soc Trans
, vol.34
, pp. 279-282
-
-
Fitch, P.M.1
Roghanian, A.2
Howie, S.E.3
Sallenave, J.M.4
-
32
-
-
54349092814
-
Altered expression of anti-microbial molecules in cigarette smoke exposed amphysematous mice lungs
-
Shibata Y., Abe S., Inoue S., Takabatake N., Igarashi A., Takeishi Y., et al. Altered expression of anti-microbial molecules in cigarette smoke exposed amphysematous mice lungs. Respirology 2008, 13:1061-1065.
-
(2008)
Respirology
, vol.13
, pp. 1061-1065
-
-
Shibata, Y.1
Abe, S.2
Inoue, S.3
Takabatake, N.4
Igarashi, A.5
Takeishi, Y.6
-
33
-
-
28244452875
-
Innate immune responses and chronic obstructive pulmonary disease. " Terminator" or " Terminator 2"
-
Schleimer R.P. Innate immune responses and chronic obstructive pulmonary disease. " Terminator" or " Terminator 2" Proc Am Thorac Soc 2005, 2:342-346.
-
(2005)
Proc Am Thorac Soc
, vol.2
, pp. 342-346
-
-
Schleimer, R.P.1
-
34
-
-
26944454482
-
Glucocorticoids suppress inflammation but spare innate immune responses in airway epithelium
-
Schleimer R.P. Glucocorticoids suppress inflammation but spare innate immune responses in airway epithelium. Proc Am Thorac Soc 2004, 1:222-230.
-
(2004)
Proc Am Thorac Soc
, vol.1
, pp. 222-230
-
-
Schleimer, R.P.1
-
35
-
-
67649182964
-
Persistence of oxidant and protease burden in the airways after smoking cessation
-
Louhelainen N., Rytila P., Haahtela T., Kinnula V., Dukanovic R. Persistence of oxidant and protease burden in the airways after smoking cessation. BMC Pulm Med 2009, 9:25. 10.1186/1471-2466-9-25.
-
(2009)
BMC Pulm Med
, vol.9
, pp. 25
-
-
Louhelainen, N.1
Rytila, P.2
Haahtela, T.3
Kinnula, V.4
Dukanovic, R.5
-
36
-
-
47849105932
-
Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease
-
Owen J.C. Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease. Int J Chron Obstruc Pulmon Dis 2008, 3:253-268.
-
(2008)
Int J Chron Obstruc Pulmon Dis
, vol.3
, pp. 253-268
-
-
Owen, J.C.1
-
37
-
-
56249146058
-
Particle clearance from the airways of subjects with bronchial hyperesponsiveness and with COPD
-
Scheuch G., Kohlhaufl M., Möller W., Brand P., Meyer T., Häussinger K., et al. Particle clearance from the airways of subjects with bronchial hyperesponsiveness and with COPD. Exp Lung Res 2008, 34:531-549.
-
(2008)
Exp Lung Res
, vol.34
, pp. 531-549
-
-
Scheuch, G.1
Kohlhaufl, M.2
Möller, W.3
Brand, P.4
Meyer, T.5
Häussinger, K.6
-
38
-
-
60649089032
-
Improving mucociliary clearance in COPD
-
Bhowmik A., Chahal K., Austin G., Chakravorty I. Improving mucociliary clearance in COPD. Respr Med 2008, 103:496-502.
-
(2008)
Respr Med
, vol.103
, pp. 496-502
-
-
Bhowmik, A.1
Chahal, K.2
Austin, G.3
Chakravorty, I.4
-
39
-
-
41749115751
-
Development of chronic bronchitis & emphysema in ENac overexpression mice
-
Mall M., Harkema J.R., Trojanek J.B., Treis D., Livraghi A., Schubert S., et al. Development of chronic bronchitis & emphysema in ENac overexpression mice. Am J Resp Crit Care Med 2008, 177:730-742.
-
(2008)
Am J Resp Crit Care Med
, vol.177
, pp. 730-742
-
-
Mall, M.1
Harkema, J.R.2
Trojanek, J.B.3
Treis, D.4
Livraghi, A.5
Schubert, S.6
-
40
-
-
33747833375
-
Cellular and molecular mechanisms of alveolar destruction in emphysema. An evolutionary perspective
-
Tuder R.M., Yoshida T., Arap W., Pasqualini R., Petrache I. Cellular and molecular mechanisms of alveolar destruction in emphysema. An evolutionary perspective. Proc Am Thorac Soc 2006, 3:503-511.
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 503-511
-
-
Tuder, R.M.1
Yoshida, T.2
Arap, W.3
Pasqualini, R.4
Petrache, I.5
-
41
-
-
70349118100
-
New paradigms in the pathogenesis of COPD
-
MacNee W., Tuder R.M. New paradigms in the pathogenesis of COPD. Proc Am Thorac Soc 2009, 6:527-531.
-
(2009)
Proc Am Thorac Soc
, vol.6
, pp. 527-531
-
-
MacNee, W.1
Tuder, R.M.2
-
42
-
-
57649221004
-
Target induction of lung endothelial cell apoptosis causes emphysema like changes in the mouse
-
Giordano R.J., Lahdenranta J., Zhen L., Chukwueke U., Petrache I., Larngley R.R., et al. Target induction of lung endothelial cell apoptosis causes emphysema like changes in the mouse. J Biol Chem 2008, 283(43):29447-29460.
-
(2008)
J Biol Chem
, vol.283
, Issue.43
, pp. 29447-29460
-
-
Giordano, R.J.1
Lahdenranta, J.2
Zhen, L.3
Chukwueke, U.4
Petrache, I.5
Larngley, R.R.6
-
43
-
-
40049104892
-
Immunology of asthma and chronic obstructive pulmonary disease
-
Barnes P.J. Immunology of asthma and chronic obstructive pulmonary disease. Nat Rev Immunol 2008, 8:183-192.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 183-192
-
-
Barnes, P.J.1
-
44
-
-
0023733047
-
Monocyte retention and migration in pulmonary inflammation. Requirement for neutrophils
-
Doherty D., Downey G., Worthern G., Haslet C., Henson P. Monocyte retention and migration in pulmonary inflammation. Requirement for neutrophils. Lab Invest 1998, 59:200-213.
-
(1998)
Lab Invest
, vol.59
, pp. 200-213
-
-
Doherty, D.1
Downey, G.2
Worthern, G.3
Haslet, C.4
Henson, P.5
-
45
-
-
0036580648
-
Effects of cigarette smoke on the immune system
-
Sopori M. Effects of cigarette smoke on the immune system. Nat Rev Immunol 2002, 2:372-377.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 372-377
-
-
Sopori, M.1
-
46
-
-
1942504217
-
Macrophage phagocytosis of apoptotic neutrophils is compromised by matrix proteins modified by cigarette smoke and lipid peroxidation products
-
Kirkham P.A., Spooner G., Rahman I., Rossi A.G. Macrophage phagocytosis of apoptotic neutrophils is compromised by matrix proteins modified by cigarette smoke and lipid peroxidation products. Biochem Biophys Res Commun 2004, 318:32-37.
-
(2004)
Biochem Biophys Res Commun
, vol.318
, pp. 32-37
-
-
Kirkham, P.A.1
Spooner, G.2
Rahman, I.3
Rossi, A.G.4
-
47
-
-
38549124293
-
Cigarette smoke exposure attenuates cytokine production by mouse alveolar macrophages
-
Gaschler G.J., Zavitz C.C.J., bauer C.M.T., Skrtic M., Lindahl M., Robbins C.S., et al. Cigarette smoke exposure attenuates cytokine production by mouse alveolar macrophages. Am J Resp Cell Mol Biol 2008, 38:218-226.
-
(2008)
Am J Resp Cell Mol Biol
, vol.38
, pp. 218-226
-
-
Gaschler, G.J.1
Zavitz, C.C.J.2
bauer, C.M.T.3
Skrtic, M.4
Lindahl, M.5
Robbins, C.S.6
-
48
-
-
49649127169
-
Multifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destruction
-
Chung K.F., Adcock I.M. Multifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destruction. Eur Resp J 2008, 31:1334-1356.
-
(2008)
Eur Resp J
, vol.31
, pp. 1334-1356
-
-
Chung, K.F.1
Adcock, I.M.2
-
49
-
-
23644442945
-
Toll like receptors and chronic lung disease
-
Chaudhuri N., Dower S.K., Whyte M.K.B., Sabroe I. Toll like receptors and chronic lung disease. Clin Sci 2005, 109:125-133.
-
(2005)
Clin Sci
, vol.109
, pp. 125-133
-
-
Chaudhuri, N.1
Dower, S.K.2
Whyte, M.K.B.3
Sabroe, I.4
-
50
-
-
40449118020
-
Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signalling dependent
-
Doz E., Noulin N., Boichot E., Guenon I., Fick L., Le Bert M., et al. Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signalling dependent. J Immunol 2008, 180:1169-1178.
-
(2008)
J Immunol
, vol.180
, pp. 1169-1178
-
-
Doz, E.1
Noulin, N.2
Boichot, E.3
Guenon, I.4
Fick, L.5
Le Bert, M.6
-
51
-
-
63349099346
-
The role of interleukin-1B in murine cigarette smoke induced emphysema and small airway remodelling
-
Churg A., Zhou S., Wang X., Wang R., Wright J.L. The role of interleukin-1B in murine cigarette smoke induced emphysema and small airway remodelling. Am J Resp Cell Mol Biol 2009, 40:482-490.
-
(2009)
Am J Resp Cell Mol Biol
, vol.40
, pp. 482-490
-
-
Churg, A.1
Zhou, S.2
Wang, X.3
Wang, R.4
Wright, J.L.5
-
52
-
-
60749115881
-
Toll-like receptor 2 is essential for the sensing of oxidants during inflammation
-
Paul-Clark M.J., McMaster S.K., Sorrentino R., Sriskandan S., Bailey L.K., Moreno L., et al. Toll-like receptor 2 is essential for the sensing of oxidants during inflammation. Am J Respir Crit Care Med 2009, 179:299-306.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 299-306
-
-
Paul-Clark, M.J.1
McMaster, S.K.2
Sorrentino, R.3
Sriskandan, S.4
Bailey, L.K.5
Moreno, L.6
-
53
-
-
34250328318
-
CC-chemokine receptors in COPD
-
Bracke K.R., Demedts I.K., Joos G.F., Brusselle G. CC-chemokine receptors in COPD. Inflammation and Allergy - Drug Targets 2007, 6:75-79.
-
(2007)
Inflammation and Allergy - Drug Targets
, vol.6
, pp. 75-79
-
-
Bracke, K.R.1
Demedts, I.K.2
Joos, G.F.3
Brusselle, G.4
-
55
-
-
0029086408
-
Effect of smoking cessation on airway inflammation in chronic bronchitis
-
Turato G., Di Stefano A., Maestrelli P., Mapp C.E., Ruggieri M.P., Roggeri A., et al. Effect of smoking cessation on airway inflammation in chronic bronchitis. Am J Respir Crit Care Med 1995, 152:1262-1267.
-
(1995)
Am J Respir Crit Care Med
, vol.152
, pp. 1262-1267
-
-
Turato, G.1
Di Stefano, A.2
Maestrelli, P.3
Mapp, C.E.4
Ruggieri, M.P.5
Roggeri, A.6
-
56
-
-
32544436757
-
Why does airway inflammation persist after the smoking stops?
-
Hogg J.C. Why does airway inflammation persist after the smoking stops?. Thorax 2006, 61:96-97.
-
(2006)
Thorax
, vol.61
, pp. 96-97
-
-
Hogg, J.C.1
-
57
-
-
38449105137
-
Airway mucosal inflammation in COPD is similar in smokers and ex-smokers: a pooled analysis
-
Gamble E., Grootendoorst D.C., Hattotuwa T., O'Shaugnessy T., Ram F.S., Qiu Y., et al. Airway mucosal inflammation in COPD is similar in smokers and ex-smokers: a pooled analysis. Eur Respir J 2007, 30:467-471.
-
(2007)
Eur Respir J
, vol.30
, pp. 467-471
-
-
Gamble, E.1
Grootendoorst, D.C.2
Hattotuwa, T.3
O'Shaugnessy, T.4
Ram, F.S.5
Qiu, Y.6
-
58
-
-
34249652351
-
Antielastin autoimmunity in tobacco smoke induced emphysema
-
Lee S.H., Goswami S., Grudo A., Song L.Z., Bandi V., Goodnight-White S., et al. Antielastin autoimmunity in tobacco smoke induced emphysema. Nat Med 2007, 13:567-569.
-
(2007)
Nat Med
, vol.13
, pp. 567-569
-
-
Lee, S.H.1
Goswami, S.2
Grudo, A.3
Song, L.Z.4
Bandi, V.5
Goodnight-White, S.6
-
59
-
-
38349070654
-
Autoantibodies in patients with COPD
-
Feghali-Bostwick C., Gadgil A.S., Otterbein E., Pliewski J.M., Stoner M., Csizmadia E., et al. Autoantibodies in patients with COPD. Am J Respir Crti Care Med 2008, 177:156-163.
-
(2008)
Am J Respir Crti Care Med
, vol.177
, pp. 156-163
-
-
Feghali-Bostwick, C.1
Gadgil, A.S.2
Otterbein, E.3
Pliewski, J.M.4
Stoner, M.5
Csizmadia, E.6
-
60
-
-
33751207741
-
Is alveolar destruction and emphysema in COPD an immune disease?
-
Tarasevicience-Stewart L., Douglas I.S., Nan-Sinkam P.S., Lee J.D., Tuder R.M., Nicolls M.R., et al. Is alveolar destruction and emphysema in COPD an immune disease?. Proc Am Thorac Soc 2006, 3:687-690.
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 687-690
-
-
Tarasevicience-Stewart, L.1
Douglas, I.S.2
Nan-Sinkam, P.S.3
Lee, J.D.4
Tuder, R.M.5
Nicolls, M.R.6
-
61
-
-
13244264742
-
Characterization of the interstitial lung and peripheral blood T cell receptor repertoire in cigarette smokers
-
Korn S., Wiewrodt R., Walz Y.C., Becker K., Mayer E., Krummenauer F., et al. Characterization of the interstitial lung and peripheral blood T cell receptor repertoire in cigarette smokers. Am J Resp Cell Mol Biol 2005, 32:142-148.
-
(2005)
Am J Resp Cell Mol Biol
, vol.32
, pp. 142-148
-
-
Korn, S.1
Wiewrodt, R.2
Walz, Y.C.3
Becker, K.4
Mayer, E.5
Krummenauer, F.6
-
62
-
-
24144433461
-
Oligoclonal CD4 T cells in the lungs of patients with severe emphysema
-
Sullivan A.K., Simonian P.L., Falta M.T., Mitchell J.D., Cosgrove G.P., Brown K.K., et al. Oligoclonal CD4 T cells in the lungs of patients with severe emphysema. Am J Respir Crit Care Med 2005, 172:590-596.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 590-596
-
-
Sullivan, A.K.1
Simonian, P.L.2
Falta, M.T.3
Mitchell, J.D.4
Cosgrove, G.P.5
Brown, K.K.6
-
63
-
-
71849094775
-
Persistence of lung CD8 T cell oligoclonal expansions upon smoking cessation in a mouse model of cigarette smoke induced emphysema
-
Motz G.T., Epprt B.L., Sun G., Wesselkamper S.C., Linke M.J., Deka R., et al. Persistence of lung CD8 T cell oligoclonal expansions upon smoking cessation in a mouse model of cigarette smoke induced emphysema. J Immunol 2008, 181:8036-8043.
-
(2008)
J Immunol
, vol.181
, pp. 8036-8043
-
-
Motz, G.T.1
Epprt, B.L.2
Sun, G.3
Wesselkamper, S.C.4
Linke, M.J.5
Deka, R.6
-
64
-
-
65649102628
-
Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease
-
Borchers M.T., Wesselkamper S.C., Curull V., Ramirez-Sarmiento A., Sanchez-Font A., Garcia-Aymerich J., et al. Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease. J Clin Invest 2009, 10.1172/JCI/JCI34462.
-
(2009)
J Clin Invest
-
-
Borchers, M.T.1
Wesselkamper, S.C.2
Curull, V.3
Ramirez-Sarmiento, A.4
Sanchez-Font, A.5
Garcia-Aymerich, J.6
-
66
-
-
57149105188
-
Infection in the pathogenesis and course of COPD
-
Sethi S., Murphy T.M. Infection in the pathogenesis and course of COPD. N Engl J Med 2008, 359:2355-2365.
-
(2008)
N Engl J Med
, vol.359
, pp. 2355-2365
-
-
Sethi, S.1
Murphy, T.M.2
-
67
-
-
17644380278
-
Microbiologic determinations of exacerbation in COPD
-
Rosell A., Monso E., Soler N., Torres F., Angrill J., Riise G., et al. Microbiologic determinations of exacerbation in COPD. Arch Intern Med 2005, 165:891-897.
-
(2005)
Arch Intern Med
, vol.165
, pp. 891-897
-
-
Rosell, A.1
Monso, E.2
Soler, N.3
Torres, F.4
Angrill, J.5
Riise, G.6
-
68
-
-
58049198428
-
Bacteriology in acute exacerbation of COPD in patients admitted to hospital
-
Larsen M.V., Janner J.H., Nielsen S.D., Friss-Moller A., Ringbaek T., Lange P. Bacteriology in acute exacerbation of COPD in patients admitted to hospital. Scand J Infect Dis 2009, 41:26-32.
-
(2009)
Scand J Infect Dis
, vol.41
, pp. 26-32
-
-
Larsen, M.V.1
Janner, J.H.2
Nielsen, S.D.3
Friss-Moller, A.4
Ringbaek, T.5
Lange, P.6
-
69
-
-
56049106616
-
Antibiotics at COPD exacerbations: the debate continues
-
Wedischa J.A. Antibiotics at COPD exacerbations: the debate continues. Thorax 2008, 63:940-942.
-
(2008)
Thorax
, vol.63
, pp. 940-942
-
-
Wedischa, J.A.1
-
70
-
-
61749103937
-
Tobramycin nebuliser solution in severe COPD patients colonised with Pseudomonas aeruginosa: effects on bronchial inflammation
-
Dal Negro R., Michelett C., Tognella S., Visconti M., Turati C. Tobramycin nebuliser solution in severe COPD patients colonised with Pseudomonas aeruginosa: effects on bronchial inflammation. Advances Ther 2008, 1019-1030.
-
(2008)
Advances Ther
, pp. 1019-1030
-
-
Dal Negro, R.1
Michelett, C.2
Tognella, S.3
Visconti, M.4
Turati, C.5
-
72
-
-
44649152300
-
Macrolides as immunomodultory medications for the therapy of chronic lung diseases
-
Lopez-Boado Y.S., Rubin B.K. Macrolides as immunomodultory medications for the therapy of chronic lung diseases. Curr Opin Pharmacol 2008, 8:286-291.
-
(2008)
Curr Opin Pharmacol
, vol.8
, pp. 286-291
-
-
Lopez-Boado, Y.S.1
Rubin, B.K.2
-
73
-
-
56049088950
-
Innate immune reponses to viral infection of the lungs
-
See H., Wark P. Innate immune reponses to viral infection of the lungs. Paediatr Respir Rev 2008, 9:243-250.
-
(2008)
Paediatr Respir Rev
, vol.9
, pp. 243-250
-
-
See, H.1
Wark, P.2
-
74
-
-
55549094831
-
Gene expression profiles during in vivo human rhinovirus infection: insights into the host response
-
Proud D., Turner R.B., Winther B., Wiehler S., Tiesman J.P., Reichling T.D., et al. Gene expression profiles during in vivo human rhinovirus infection: insights into the host response. Am J Resp Crit Care Med 2008, 178:962-968.
-
(2008)
Am J Resp Crit Care Med
, vol.178
, pp. 962-968
-
-
Proud, D.1
Turner, R.B.2
Winther, B.3
Wiehler, S.4
Tiesman, J.P.5
Reichling, T.D.6
-
75
-
-
57149092123
-
Rhinovirus disrupts the barrier function of polarised airway epithelial cells
-
Saijan U., Wang Q., Zhao Y., Gruenert D.C., Hershenson M.B. Rhinovirus disrupts the barrier function of polarised airway epithelial cells. Am J Resp Crit Care Med 2008, 178:1271-1281.
-
(2008)
Am J Resp Crit Care Med
, vol.178
, pp. 1271-1281
-
-
Saijan, U.1
Wang, Q.2
Zhao, Y.3
Gruenert, D.C.4
Hershenson, M.B.5
-
76
-
-
34948886712
-
Adaptive immune cells temper initial innate reponses
-
Kim K.D., Zhao J., Auh S., Yang X., Du P., Tang H., et al. Adaptive immune cells temper initial innate reponses. Nat Med 2007, 13:1248-1252.
-
(2007)
Nat Med
, vol.13
, pp. 1248-1252
-
-
Kim, K.D.1
Zhao, J.2
Auh, S.3
Yang, X.4
Du, P.5
Tang, H.6
-
77
-
-
34547640283
-
Interleukin 17A modulates human airway epithelial responses to human rhinovirus infection
-
Wiehler S., Proud D. Interleukin 17A modulates human airway epithelial responses to human rhinovirus infection. Am J Physiol Lung Cell Mol Physiol 2007, 292:L505-L515.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
-
-
Wiehler, S.1
Proud, D.2
-
78
-
-
35148862090
-
The immunopathogenesis of COPD: insights from recent research
-
Curtis J.L., Freeman C.M., Hogg J.C. The immunopathogenesis of COPD: insights from recent research. Proc A Thorac Soc 2007, 4:512-521.
-
(2007)
Proc A Thorac Soc
, vol.4
, pp. 512-521
-
-
Curtis, J.L.1
Freeman, C.M.2
Hogg, J.C.3
-
79
-
-
65249145291
-
TNF/iNOS producing dendritic cells are the necessary evil of lethal influenza virus infection
-
Aldridge J.R., Mosely C.F., Boltz D.A., Negovetich N.J., Reynolds C., Franks J., et al. TNF/iNOS producing dendritic cells are the necessary evil of lethal influenza virus infection. Proc Natl Acad Sci USA 2009, 106:5306-5311.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 5306-5311
-
-
Aldridge, J.R.1
Mosely, C.F.2
Boltz, D.A.3
Negovetich, N.J.4
Reynolds, C.5
Franks, J.6
-
80
-
-
65249155426
-
Tiping the balance in favor of protective immunity during influenza infection
-
Pamer E.G. Tiping the balance in favor of protective immunity during influenza infection. Proc Natl Acad Sci USA 2009, 106:4961-4962.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 4961-4962
-
-
Pamer, E.G.1
-
81
-
-
48749097634
-
Cigarette smoke selectively enhances viral PAMP and virus induced pulmonary innate immune and remodelling responses in mice
-
Kang M.-J., Geun Lee G., Lee J.-Y., Dela Cruz C.S., Chen Z.J., Enelow R., et al. Cigarette smoke selectively enhances viral PAMP and virus induced pulmonary innate immune and remodelling responses in mice. J Clin Invest 2008, 118:2771-2784.
-
(2008)
J Clin Invest
, vol.118
, pp. 2771-2784
-
-
Kang, M.-J.1
Geun Lee, G.2
Lee, J.-Y.3
Dela Cruz, C.S.4
Chen, Z.J.5
Enelow, R.6
-
82
-
-
44949257271
-
Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease
-
Kim E.Y., Battaile J.T., Patel A.C., You Y., Agapov E., Grayson M.N., et al. Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease. Nat Med 2008, 14:633-640.
-
(2008)
Nat Med
, vol.14
, pp. 633-640
-
-
Kim, E.Y.1
Battaile, J.T.2
Patel, A.C.3
You, Y.4
Agapov, E.5
Grayson, M.N.6
-
83
-
-
0034606218
-
Interferon gamma induction of pulmonary emphysema in the adult murine lung
-
Wang Z., Zheng T., Zhu Z., Homer R.J., Riese R.J., Chapman H.A., et al. Interferon gamma induction of pulmonary emphysema in the adult murine lung. J Exp Med 2000, 4:1587-1600.
-
(2000)
J Exp Med
, vol.4
, pp. 1587-1600
-
-
Wang, Z.1
Zheng, T.2
Zhu, Z.3
Homer, R.J.4
Riese, R.J.5
Chapman, H.A.6
-
84
-
-
33644828187
-
A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation
-
Weathington N.M., van Houwelingen A.H., Noerager B.D., Jackson P.L., Kraneveld A.D., Galin F.S., et al. A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation. Nat Med 2005, 12:317-323.
-
(2005)
Nat Med
, vol.12
, pp. 317-323
-
-
Weathington, N.M.1
van Houwelingen, A.H.2
Noerager, B.D.3
Jackson, P.L.4
Kraneveld, A.D.5
Galin, F.S.6
-
85
-
-
51349165795
-
Induction of lung emphysema is prevented by L-arginine-threonine-arginine
-
Houwelingen Van, Weathington N.M., Verweij V., Blalock J.E., Nijkamp F.P., Folkerts G. Induction of lung emphysema is prevented by L-arginine-threonine-arginine. FASEB J 2008, 22:3403-3408.
-
(2008)
FASEB J
, vol.22
, pp. 3403-3408
-
-
Houwelingen, V.1
Weathington, N.M.2
Verweij, V.3
Blalock, J.E.4
Nijkamp, F.P.5
Folkerts, G.6
-
86
-
-
40649107868
-
Interaction between smoking and genetic factors in the development of chronic bronchitis
-
Hallberg J., Dominicus A., Erkisson U.K., Gerhardsson de Verdier M., Pedersen N.L., Dahläack M., et al. Interaction between smoking and genetic factors in the development of chronic bronchitis. Am J Respir Crit Care Med 2008, 177:486-490.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 486-490
-
-
Hallberg, J.1
Dominicus, A.2
Erkisson, U.K.3
Gerhardsson de Verdier, M.4
Pedersen, N.L.5
Dahläack, M.6
-
87
-
-
0038289107
-
Effects of the GSTM1 and GSTT1 polymorphisms on the relationship between maternal exposure to environmental tobacco smoke and neonatal birth weight
-
Hong Y.C., Lee K.H., Son B.K., Ha E.H., Moon H.S., Ha M. Effects of the GSTM1 and GSTT1 polymorphisms on the relationship between maternal exposure to environmental tobacco smoke and neonatal birth weight. J Occup Environ Med 2003, 45:492-498.
-
(2003)
J Occup Environ Med
, vol.45
, pp. 492-498
-
-
Hong, Y.C.1
Lee, K.H.2
Son, B.K.3
Ha, E.H.4
Moon, H.S.5
Ha, M.6
-
88
-
-
0029086857
-
Maternal smoking during pregnancy: effects on lung function during the first 18 months of life
-
Tager I.B., Ngo L., Hanrahan J.P. Maternal smoking during pregnancy: effects on lung function during the first 18 months of life. Am J Resp Crit Care Med 1995, 152:977-983.
-
(1995)
Am J Resp Crit Care Med
, vol.152
, pp. 977-983
-
-
Tager, I.B.1
Ngo, L.2
Hanrahan, J.P.3
-
89
-
-
0033035039
-
Physiological chances in respiratory function associated with ageing
-
Janssens J.P., Pache J.C., Nicod L.P. Physiological chances in respiratory function associated with ageing. Eur Resp J 1999, 13:197-205.
-
(1999)
Eur Resp J
, vol.13
, pp. 197-205
-
-
Janssens, J.P.1
Pache, J.C.2
Nicod, L.P.3
-
90
-
-
58149100407
-
The ageing immune system: is it ever too old to become young again?
-
Dorshkind K., Montecino-Rodriguex Encarnacion, Signer R.A. The ageing immune system: is it ever too old to become young again?. Nat Rev Immunol 2009, 9:57-62.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 57-62
-
-
Dorshkind, K.1
Montecino-Rodriguex, E.2
Signer, R.A.3
-
91
-
-
5444225275
-
Impaired innate immunity predicts frailty in old age. The Leiden 85 plus study
-
van den Biggelaar A.H., Huizinga T.W., de Craen A.J., Gussekloo J., Heijmans B.T., Frölich M., et al. Impaired innate immunity predicts frailty in old age. The Leiden 85 plus study. Exp Gerontol 2004, 39:1407-1414.
-
(2004)
Exp Gerontol
, vol.39
, pp. 1407-1414
-
-
van den Biggelaar, A.H.1
Huizinga, T.W.2
de Craen, A.J.3
Gussekloo, J.4
Heijmans, B.T.5
Frölich, M.6
-
92
-
-
53849116091
-
Role of IL-10 in the resolution of airway inflammation
-
Ogawa Y., Duru E.A., Ameredes B.T. Role of IL-10 in the resolution of airway inflammation. Curr Mol Med 2008, 8:437-445.
-
(2008)
Curr Mol Med
, vol.8
, pp. 437-445
-
-
Ogawa, Y.1
Duru, E.A.2
Ameredes, B.T.3
-
93
-
-
42649146208
-
SIRT1, an antinflammatory and antiaging protein is decreased in lungs of patients with COPD
-
Rajendrasozhan R., Yang S.R., Kinula V.L., Rahman I. SIRT1, an antinflammatory and antiaging protein is decreased in lungs of patients with COPD. Am J Resp Crit Care Med 2008, 177:861-870.
-
(2008)
Am J Resp Crit Care Med
, vol.177
, pp. 861-870
-
-
Rajendrasozhan, R.1
Yang, S.R.2
Kinula, V.L.3
Rahman, I.4
-
94
-
-
33748329453
-
Aging and cigarette smoke: fueling the fire
-
Tuder R. Aging and cigarette smoke: fueling the fire. Am J Resp & Critical Care Medicine 2006, 17:490-491.
-
(2006)
Am J Resp & Critical Care Medicine
, vol.17
, pp. 490-491
-
-
Tuder, R.1
-
95
-
-
4544322522
-
Inflammatory exposure and historial changes in human life spans
-
Finch C.E., Crimmins E.M. Inflammatory exposure and historial changes in human life spans. Science 2004, 305:1736-1739.
-
(2004)
Science
, vol.305
, pp. 1736-1739
-
-
Finch, C.E.1
Crimmins, E.M.2
|