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Volumn 18, Issue 1, 2007, Pages 4-11

A sense of time: how molecular clocks organize metabolism

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOGENESIS; CIRCADIAN RHYTHM; DIABETES MELLITUS; FEEDBACK SYSTEM; FEEDING; FOOD INTAKE; GENETIC TRANSCRIPTION; GLUCONEOGENESIS; GLUCOSE TRANSPORT; HUMAN; LIPOLYSIS; MAMMAL; METABOLISM; MITOCHONDRIAL RESPIRATION; MOLECULAR CLOCK; NONHUMAN; OBESITY; OXIDATIVE PHOSPHORYLATION; PHYSICAL ACTIVITY; PRIORITY JOURNAL; REVIEW; RNA TRANSLATION; SLEEP DISORDER; SLEEP PATTERN; TRANSCRIPTION REGULATION;

EID: 33845665236     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tem.2006.11.005     Document Type: Review
Times cited : (207)

References (86)
  • 2
    • 17844364468 scopus 로고    scopus 로고
    • The rhythm of rest and excess
    • Foster R.G., and Wulff K. The rhythm of rest and excess. Nat. Rev. Neurosci. 6 (2005) 407-414
    • (2005) Nat. Rev. Neurosci. , vol.6 , pp. 407-414
    • Foster, R.G.1    Wulff, K.2
  • 3
    • 0033843592 scopus 로고    scopus 로고
    • Physiological effects of light on the human circadian pacemaker
    • Shanahan T.L., and Czeisler C.A. Physiological effects of light on the human circadian pacemaker. Semin. Perinatol. 24 (2000) 299-320
    • (2000) Semin. Perinatol. , vol.24 , pp. 299-320
    • Shanahan, T.L.1    Czeisler, C.A.2
  • 4
    • 11844259365 scopus 로고    scopus 로고
    • Sleepless in America: a pathway to obesity and the metabolic syndrome?
    • Bass J., and Turek F.W. Sleepless in America: a pathway to obesity and the metabolic syndrome?. Arch. Intern. Med. 165 (2005) 15-16
    • (2005) Arch. Intern. Med. , vol.165 , pp. 15-16
    • Bass, J.1    Turek, F.W.2
  • 5
    • 30044448307 scopus 로고    scopus 로고
    • When the Clock stops ticking, metabolic syndrome explodes
    • Staels B. When the Clock stops ticking, metabolic syndrome explodes. Nat. Med. 12 (2006) 54-55
    • (2006) Nat. Med. , vol.12 , pp. 54-55
    • Staels, B.1
  • 7
    • 28844502722 scopus 로고    scopus 로고
    • Timeline: circadian clocks - the fall and rise of physiology
    • Roenneberg T., and Merrow M. Timeline: circadian clocks - the fall and rise of physiology. Nat. Rev. Mol. Cell Biol. 6 (2005) 965-971
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 965-971
    • Roenneberg, T.1    Merrow, M.2
  • 8
    • 0042490526 scopus 로고    scopus 로고
    • A clockwork web: circadian timing in brain and periphery, in health and disease
    • Hastings M.H., et al. A clockwork web: circadian timing in brain and periphery, in health and disease. Nat. Rev. Neurosci. 4 (2003) 649-661
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 649-661
    • Hastings, M.H.1
  • 9
    • 14644423201 scopus 로고    scopus 로고
    • Orchestrating time: arrangements of the brain circadian clock
    • Antle M.C., and Silver R. Orchestrating time: arrangements of the brain circadian clock. Trends Neurosci. 28 (2005) 145-151
    • (2005) Trends Neurosci. , vol.28 , pp. 145-151
    • Antle, M.C.1    Silver, R.2
  • 10
    • 0025021084 scopus 로고
    • Transplanted suprachiasmatic nucleus determines circadian period
    • Ralph M.R., et al. Transplanted suprachiasmatic nucleus determines circadian period. Science 247 (1990) 975-978
    • (1990) Science , vol.247 , pp. 975-978
    • Ralph, M.R.1
  • 11
    • 0035930732 scopus 로고    scopus 로고
    • Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling
    • Kramer A., et al. Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling. Science 294 (2001) 2511-2515
    • (2001) Science , vol.294 , pp. 2511-2515
    • Kramer, A.1
  • 12
    • 0029781519 scopus 로고    scopus 로고
    • A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms
    • Silver R., et al. A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms. Nature 382 (1996) 810-813
    • (1996) Nature , vol.382 , pp. 810-813
    • Silver, R.1
  • 13
    • 0037161808 scopus 로고    scopus 로고
    • Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus
    • Cheng M.Y., et al. Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus. Nature 417 (2002) 405-410
    • (2002) Nature , vol.417 , pp. 405-410
    • Cheng, M.Y.1
  • 14
    • 0032896113 scopus 로고    scopus 로고
    • Effects of suprachiasmatic transplants on circadian rhythms of neuroendocrine function in golden hamsters
    • Meyer-Bernstein E.L., et al. Effects of suprachiasmatic transplants on circadian rhythms of neuroendocrine function in golden hamsters. Endocrinology 140 (1999) 207-218
    • (1999) Endocrinology , vol.140 , pp. 207-218
    • Meyer-Bernstein, E.L.1
  • 15
    • 33646468639 scopus 로고    scopus 로고
    • The regulation of neuroendocrine function: timing is everything
    • Kriegsfeld L.J., and Silver R. The regulation of neuroendocrine function: timing is everything. Horm. Behav. 49 (2006) 557-574
    • (2006) Horm. Behav. , vol.49 , pp. 557-574
    • Kriegsfeld, L.J.1    Silver, R.2
  • 16
    • 14644435678 scopus 로고    scopus 로고
    • The hypothalamic integrator for circadian rhythms
    • Saper C.B., et al. The hypothalamic integrator for circadian rhythms. Trends Neurosci. 28 (2005) 152-157
    • (2005) Trends Neurosci. , vol.28 , pp. 152-157
    • Saper, C.B.1
  • 17
    • 0035991390 scopus 로고    scopus 로고
    • Output pathways of the mammalian suprachiasmatic nucleus: coding circadian time by transmitter selection and specific targeting
    • Kalsbeek A., and Buijs R.M. Output pathways of the mammalian suprachiasmatic nucleus: coding circadian time by transmitter selection and specific targeting. Cell Tissue Res. 309 (2002) 109-118
    • (2002) Cell Tissue Res. , vol.309 , pp. 109-118
    • Kalsbeek, A.1    Buijs, R.M.2
  • 18
    • 0033038418 scopus 로고    scopus 로고
    • Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
    • Kalra S.P., et al. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr. Rev. 20 (1999) 68-100
    • (1999) Endocr. Rev. , vol.20 , pp. 68-100
    • Kalra, S.P.1
  • 19
    • 0035847577 scopus 로고    scopus 로고
    • The suprachiasmatic nucleus projects to posterior hypothalamic arousal systems
    • Abrahamson E.E., et al. The suprachiasmatic nucleus projects to posterior hypothalamic arousal systems. Neuroreport 12 (2001) 435-440
    • (2001) Neuroreport , vol.12 , pp. 435-440
    • Abrahamson, E.E.1
  • 20
    • 0033082380 scopus 로고    scopus 로고
    • From lesions to leptin: hypothalamic control of food intake and body weight
    • Elmquist J.K., et al. From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 22 (1999) 221-232
    • (1999) Neuron , vol.22 , pp. 221-232
    • Elmquist, J.K.1
  • 21
    • 0034994462 scopus 로고    scopus 로고
    • SCN efferents to peripheral tissues: implications for biological rhythms
    • Bartness T.J., et al. SCN efferents to peripheral tissues: implications for biological rhythms. J. Biol. Rhythms 16 (2001) 196-204
    • (2001) J. Biol. Rhythms , vol.16 , pp. 196-204
    • Bartness, T.J.1
  • 22
    • 0035911803 scopus 로고    scopus 로고
    • Parasympathetic and sympathetic control of the pancreas: a role for the suprachiasmatic nucleus and other hypothalamic centers that are involved in the regulation of food intake
    • Buijs R.M., et al. Parasympathetic and sympathetic control of the pancreas: a role for the suprachiasmatic nucleus and other hypothalamic centers that are involved in the regulation of food intake. J. Comp. Neurol. 431 (2001) 405-423
    • (2001) J. Comp. Neurol. , vol.431 , pp. 405-423
    • Buijs, R.M.1
  • 23
    • 32644439916 scopus 로고    scopus 로고
    • The brain and the metabolic syndrome: not a wireless connection
    • Perez-Tilve D., et al. The brain and the metabolic syndrome: not a wireless connection. Endocrinology 147 (2006) 1136-1139
    • (2006) Endocrinology , vol.147 , pp. 1136-1139
    • Perez-Tilve, D.1
  • 24
    • 32644451260 scopus 로고    scopus 로고
    • Tracing from fat tissue, liver, and pancreas: a neuroanatomical framework for the role of the brain in type 2 diabetes
    • Kreier F., et al. Tracing from fat tissue, liver, and pancreas: a neuroanatomical framework for the role of the brain in type 2 diabetes. Endocrinology 147 (2006) 1140-1147
    • (2006) Endocrinology , vol.147 , pp. 1140-1147
    • Kreier, F.1
  • 25
    • 16244383657 scopus 로고    scopus 로고
    • A brain-liver circuit regulates glucose homeostasis
    • Pocai A., et al. A brain-liver circuit regulates glucose homeostasis. Cell Metab. 1 (2005) 53-61
    • (2005) Cell Metab. , vol.1 , pp. 53-61
    • Pocai, A.1
  • 26
    • 33344469291 scopus 로고    scopus 로고
    • The dorsomedial hypothalamic nucleus is critical for the expression of food-entrainable circadian rhythms
    • Gooley J.J., et al. The dorsomedial hypothalamic nucleus is critical for the expression of food-entrainable circadian rhythms. Nat. Neurosci. 9 (2006) 398-407
    • (2006) Nat. Neurosci. , vol.9 , pp. 398-407
    • Gooley, J.J.1
  • 27
    • 33747058480 scopus 로고    scopus 로고
    • The dorsomedial hypothalamic nucleus as a putative food-entrainable circadian pacemaker
    • Mieda M., et al. The dorsomedial hypothalamic nucleus as a putative food-entrainable circadian pacemaker. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 12150-12155
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 12150-12155
    • Mieda, M.1
  • 28
    • 33744832402 scopus 로고    scopus 로고
    • Persistence of a behavioral food-anticipatory circadian rhythm following dorsomedial hypothalamic ablation in rats
    • Landry G.J., et al. Persistence of a behavioral food-anticipatory circadian rhythm following dorsomedial hypothalamic ablation in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 290 (2006) R1527-R1534
    • (2006) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.290
    • Landry, G.J.1
  • 29
    • 0028215250 scopus 로고
    • Circadian food-anticipatory activity: formal models and physiological mechanisms
    • Mistlberger R.E. Circadian food-anticipatory activity: formal models and physiological mechanisms. Neurosci. Biobehav. Rev. 18 (1994) 171-195
    • (1994) Neurosci. Biobehav. Rev. , vol.18 , pp. 171-195
    • Mistlberger, R.E.1
  • 30
    • 0036674316 scopus 로고    scopus 로고
    • The 'other' circadian system: food as a Zeitgeber
    • Stephan F.K. The 'other' circadian system: food as a Zeitgeber. J. Biol. Rhythms 17 (2002) 284-292
    • (2002) J. Biol. Rhythms , vol.17 , pp. 284-292
    • Stephan, F.K.1
  • 32
    • 0030885313 scopus 로고    scopus 로고
    • RIGUI, a putative mammalian ortholog of the Drosophila period gene
    • Sun Z.S., et al. RIGUI, a putative mammalian ortholog of the Drosophila period gene. Cell 90 (1997) 1003-1011
    • (1997) Cell , vol.90 , pp. 1003-1011
    • Sun, Z.S.1
  • 33
    • 0030800739 scopus 로고    scopus 로고
    • Circadian oscillation of a mammalian homologue of the Drosophila period gene
    • Tei H., et al. Circadian oscillation of a mammalian homologue of the Drosophila period gene. Nature 389 (1997) 512-516
    • (1997) Nature , vol.389 , pp. 512-516
    • Tei, H.1
  • 34
    • 0345596433 scopus 로고    scopus 로고
    • A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light
    • Albrecht U., et al. A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light. Cell 91 (1997) 1055-1064
    • (1997) Cell , vol.91 , pp. 1055-1064
    • Albrecht, U.1
  • 35
    • 0031472474 scopus 로고    scopus 로고
    • Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei
    • Shearman L.P., et al. Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei. Neuron 19 (1997) 1261-1269
    • (1997) Neuron , vol.19 , pp. 1261-1269
    • Shearman, L.P.1
  • 36
    • 7344261271 scopus 로고    scopus 로고
    • A new mammalian period gene predominantly expressed in the suprachiasmatic nucleus
    • Takumi T., et al. A new mammalian period gene predominantly expressed in the suprachiasmatic nucleus. Genes Cells 3 (1998) 167-176
    • (1998) Genes Cells , vol.3 , pp. 167-176
    • Takumi, T.1
  • 37
    • 0032541435 scopus 로고    scopus 로고
    • A light-independent oscillatory gene mPer3 in mouse SCN and OVLT
    • Takumi T., et al. A light-independent oscillatory gene mPer3 in mouse SCN and OVLT. EMBO J. 17 (1998) 4753-4759
    • (1998) EMBO J. , vol.17 , pp. 4753-4759
    • Takumi, T.1
  • 38
    • 0025044560 scopus 로고
    • Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels
    • Hardin P.E., et al. Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels. Nature 343 (1990) 536-540
    • (1990) Nature , vol.343 , pp. 536-540
    • Hardin, P.E.1
  • 39
    • 15044341917 scopus 로고    scopus 로고
    • Cellular oscillators: rhythmic gene expression and metabolism
    • Schibler U., and Naef F. Cellular oscillators: rhythmic gene expression and metabolism. Curr. Opin. Cell Biol. 17 (2005) 223-229
    • (2005) Curr. Opin. Cell Biol. , vol.17 , pp. 223-229
    • Schibler, U.1    Naef, F.2
  • 40
    • 20044396172 scopus 로고    scopus 로고
    • A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo
    • Yoo S.H., et al. A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 2608-2613
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 2608-2613
    • Yoo, S.H.1
  • 41
    • 33749031807 scopus 로고    scopus 로고
    • Molecular components of the mammalian circadian clock
    • Ko C.H., and Takahashi J.S. Molecular components of the mammalian circadian clock. Hum. Mol. Genet. 15 Suppl. 2 (2006) R271-R277
    • (2006) Hum. Mol. Genet. , vol.15 , Issue.SUPPL. 2
    • Ko, C.H.1    Takahashi, J.S.2
  • 42
    • 13944254430 scopus 로고    scopus 로고
    • System-level identification of transcriptional circuits underlying mammalian circadian clocks
    • Ueda H.R., et al. System-level identification of transcriptional circuits underlying mammalian circadian clocks. Nat. Genet. 37 (2005) 187-192
    • (2005) Nat. Genet. , vol.37 , pp. 187-192
    • Ueda, H.R.1
  • 43
    • 0037178787 scopus 로고    scopus 로고
    • The orphan nuclear receptor REV-ERBα controls circadian transcription within the positive limb of the mammalian circadian oscillator
    • Preitner N., et al. The orphan nuclear receptor REV-ERBα controls circadian transcription within the positive limb of the mammalian circadian oscillator. Cell 110 (2002) 251-260
    • (2002) Cell , vol.110 , pp. 251-260
    • Preitner, N.1
  • 44
    • 0024522826 scopus 로고
    • A novel member of the thyroid/steroid hormone receptor family is encoded by the opposite strand of the rat c-erbA α transcriptional unit
    • Lazar M.A., et al. A novel member of the thyroid/steroid hormone receptor family is encoded by the opposite strand of the rat c-erbA α transcriptional unit. Mol. Cell. Biol. 9 (1989) 1128-1136
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 1128-1136
    • Lazar, M.A.1
  • 45
    • 12644279862 scopus 로고    scopus 로고
    • Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system
    • Zhou Y.D., et al. Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 713-718
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 713-718
    • Zhou, Y.D.1
  • 46
    • 33644625748 scopus 로고    scopus 로고
    • Feedback repression is required for mammalian circadian clock function
    • Sato T.K., et al. Feedback repression is required for mammalian circadian clock function. Nat. Genet. 38 (2006) 312-319
    • (2006) Nat. Genet. , vol.38 , pp. 312-319
    • Sato, T.K.1
  • 47
    • 33745503975 scopus 로고    scopus 로고
    • JETLAG resets the Drosophila circadian clock by promoting light-induced degradation of TIMELESS
    • Koh K., et al. JETLAG resets the Drosophila circadian clock by promoting light-induced degradation of TIMELESS. Science 312 (2006) 1809-1812
    • (2006) Science , vol.312 , pp. 1809-1812
    • Koh, K.1
  • 48
    • 33645961290 scopus 로고    scopus 로고
    • Large-scale mutagenesis and phenotypic screens for the nervous system and behavior in mice
    • Vitaterna M.H., et al. Large-scale mutagenesis and phenotypic screens for the nervous system and behavior in mice. Trends Neurosci. 29 (2006) 233-240
    • (2006) Trends Neurosci. , vol.29 , pp. 233-240
    • Vitaterna, M.H.1
  • 49
    • 4544219781 scopus 로고    scopus 로고
    • Finding new clock components: past and future
    • Takahashi J.S. Finding new clock components: past and future. J. Biol. Rhythms 19 (2004) 339-347
    • (2004) J. Biol. Rhythms , vol.19 , pp. 339-347
    • Takahashi, J.S.1
  • 50
    • 0038681910 scopus 로고    scopus 로고
    • Drosophila clock can generate ectopic circadian clocks
    • Zhao J., et al. Drosophila clock can generate ectopic circadian clocks. Cell 113 (2003) 755-766
    • (2003) Cell , vol.113 , pp. 755-766
    • Zhao, J.1
  • 51
    • 33646130147 scopus 로고    scopus 로고
    • A clock shock: mouse CLOCK is not required for circadian oscillator function
    • Debruyne J.P., et al. A clock shock: mouse CLOCK is not required for circadian oscillator function. Neuron 50 (2006) 465-477
    • (2006) Neuron , vol.50 , pp. 465-477
    • Debruyne, J.P.1
  • 52
    • 0034697099 scopus 로고    scopus 로고
    • Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau
    • Lowrey P.L., et al. Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau. Science 288 (2000) 483-492
    • (2000) Science , vol.288 , pp. 483-492
    • Lowrey, P.L.1
  • 53
    • 22344447747 scopus 로고    scopus 로고
    • Casein kinase 2, circadian clocks, and the flight from mutagenic light
    • Allada R., and Meissner R.A. Casein kinase 2, circadian clocks, and the flight from mutagenic light. Mol. Cell. Biochem. 274 (2005) 141-149
    • (2005) Mol. Cell. Biochem. , vol.274 , pp. 141-149
    • Allada, R.1    Meissner, R.A.2
  • 54
    • 0037086535 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein
    • Yagita K., et al. Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein. EMBO J. 21 (2002) 1301-1314
    • (2002) EMBO J. , vol.21 , pp. 1301-1314
    • Yagita, K.1
  • 55
    • 0042626226 scopus 로고    scopus 로고
    • BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system
    • Kondratov R.V., et al. BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system. Genes Dev. 17 (2003) 1921-1932
    • (2003) Genes Dev. , vol.17 , pp. 1921-1932
    • Kondratov, R.V.1
  • 56
    • 17244373578 scopus 로고    scopus 로고
    • Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro
    • Nakajima M., et al. Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro. Science 308 (2005) 414-415
    • (2005) Science , vol.308 , pp. 414-415
    • Nakajima, M.1
  • 57
    • 0032511229 scopus 로고    scopus 로고
    • A serum shock induces circadian gene expression in mammalian tissue culture cells
    • Balsalobre A., et al. A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell 93 (1998) 929-937
    • (1998) Cell , vol.93 , pp. 929-937
    • Balsalobre, A.1
  • 58
    • 0034724728 scopus 로고    scopus 로고
    • Resetting central and peripheral circadian oscillators in transgenic rats
    • Yamazaki S., et al. Resetting central and peripheral circadian oscillators in transgenic rats. Science 288 (2000) 682-685
    • (2000) Science , vol.288 , pp. 682-685
    • Yamazaki, S.1
  • 59
    • 0035910387 scopus 로고    scopus 로고
    • Entrainment of the circadian clock in the liver by feeding
    • Stokkan K.A., et al. Entrainment of the circadian clock in the liver by feeding. Science 291 (2001) 490-493
    • (2001) Science , vol.291 , pp. 490-493
    • Stokkan, K.A.1
  • 60
    • 18444414586 scopus 로고    scopus 로고
    • Coordinated transcription of key pathways in the mouse by the circadian clock
    • Panda S., et al. Coordinated transcription of key pathways in the mouse by the circadian clock. Cell 109 (2002) 307-320
    • (2002) Cell , vol.109 , pp. 307-320
    • Panda, S.1
  • 61
    • 33645768796 scopus 로고    scopus 로고
    • Circadian clocks are resounding in peripheral tissues
    • Ptitsyn A.A., et al. Circadian clocks are resounding in peripheral tissues. PLoS Comput. Biol. 2 (2006) e16
    • (2006) PLoS Comput. Biol. , vol.2
    • Ptitsyn, A.A.1
  • 62
    • 0036682099 scopus 로고    scopus 로고
    • A transcription factor response element for gene expression during circadian night
    • Ueda H.R., et al. A transcription factor response element for gene expression during circadian night. Nature 418 (2002) 534-539
    • (2002) Nature , vol.418 , pp. 534-539
    • Ueda, H.R.1
  • 63
    • 0037007625 scopus 로고    scopus 로고
    • Extensive and divergent circadian gene expression in liver and heart
    • Storch K.F., et al. Extensive and divergent circadian gene expression in liver and heart. Nature 417 (2002) 78-83
    • (2002) Nature , vol.417 , pp. 78-83
    • Storch, K.F.1
  • 64
    • 33645790960 scopus 로고    scopus 로고
    • Characterization of peripheral circadian clocks in adipose tissues
    • Zvonic S., et al. Characterization of peripheral circadian clocks in adipose tissues. Diabetes 55 (2006) 962-970
    • (2006) Diabetes , vol.55 , pp. 962-970
    • Zvonic, S.1
  • 65
    • 33744515807 scopus 로고    scopus 로고
    • Circadian orchestration of the hepatic proteome
    • Reddy A.B., et al. Circadian orchestration of the hepatic proteome. Curr. Biol. 16 (2006) 1107-1115
    • (2006) Curr. Biol. , vol.16 , pp. 1107-1115
    • Reddy, A.B.1
  • 66
    • 23944470712 scopus 로고    scopus 로고
    • Circadian clock control by SUMOylation of BMAL1
    • Cardone L., et al. Circadian clock control by SUMOylation of BMAL1. Science 309 (2005) 1390-1394
    • (2005) Science , vol.309 , pp. 1390-1394
    • Cardone, L.1
  • 67
    • 18444391229 scopus 로고    scopus 로고
    • SREBP-1 as a transcriptional integrator of circadian and nutritional cues in the liver
    • Brewer M., et al. SREBP-1 as a transcriptional integrator of circadian and nutritional cues in the liver. J. Biol. Rhythms 20 (2005) 195-205
    • (2005) J. Biol. Rhythms , vol.20 , pp. 195-205
    • Brewer, M.1
  • 68
    • 33747157406 scopus 로고    scopus 로고
    • Nuclear receptor expression links the circadian clock to metabolism
    • Yang X., et al. Nuclear receptor expression links the circadian clock to metabolism. Cell 126 (2006) 801-810
    • (2006) Cell , vol.126 , pp. 801-810
    • Yang, X.1
  • 69
    • 0027237512 scopus 로고
    • Induction of Rev-ErbA α, an orphan receptor encoded on the opposite strand of the alpha-thyroid hormone receptor gene, during adipocyte differentiation
    • Chawla A., and Lazar M.A. Induction of Rev-ErbA α, an orphan receptor encoded on the opposite strand of the alpha-thyroid hormone receptor gene, during adipocyte differentiation. J. Biol. Chem. 268 (1993) 16265-16269
    • (1993) J. Biol. Chem. , vol.268 , pp. 16265-16269
    • Chawla, A.1    Lazar, M.A.2
  • 70
    • 4143142003 scopus 로고    scopus 로고
    • A functional genomics strategy reveals Rora as a component of the mammalian circadian clock
    • Sato T.K., et al. A functional genomics strategy reveals Rora as a component of the mammalian circadian clock. Neuron 43 (2004) 527-537
    • (2004) Neuron , vol.43 , pp. 527-537
    • Sato, T.K.1
  • 71
    • 4344668155 scopus 로고    scopus 로고
    • RORα regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR
    • Lau P., et al. RORα regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR. J. Biol. Chem. 279 (2004) 36828-36840
    • (2004) J. Biol. Chem. , vol.279 , pp. 36828-36840
    • Lau, P.1
  • 72
    • 22944434929 scopus 로고    scopus 로고
    • Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
    • Yang Q., et al. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature 436 (2005) 356-362
    • (2005) Nature , vol.436 , pp. 356-362
    • Yang, Q.1
  • 73
    • 0035967914 scopus 로고    scopus 로고
    • Regulation of CLOCK and MOP4 by nuclear hormone receptors in the vasculature: a humoral mechanism to reset a peripheral clock
    • McNamara P., et al. Regulation of CLOCK and MOP4 by nuclear hormone receptors in the vasculature: a humoral mechanism to reset a peripheral clock. Cell 105 (2001) 877-889
    • (2001) Cell , vol.105 , pp. 877-889
    • McNamara, P.1
  • 74
    • 0035875069 scopus 로고    scopus 로고
    • A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock
    • Martinek S., et al. A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock. Cell 105 (2001) 769-779
    • (2001) Cell , vol.105 , pp. 769-779
    • Martinek, S.1
  • 75
    • 33144465537 scopus 로고    scopus 로고
    • Nuclear receptor Rev-erbα is a critical lithium-sensitive component of the circadian clock
    • Yin L., et al. Nuclear receptor Rev-erbα is a critical lithium-sensitive component of the circadian clock. Science 311 (2006) 1002-1005
    • (2006) Science , vol.311 , pp. 1002-1005
    • Yin, L.1
  • 76
    • 33746591126 scopus 로고    scopus 로고
    • Reciprocal regulation of brain and muscle Arnt-like protein 1 and peroxisome proliferator-activated receptor α defines a novel positive feedback loop in the rodent liver circadian clock
    • Canaple L., et al. Reciprocal regulation of brain and muscle Arnt-like protein 1 and peroxisome proliferator-activated receptor α defines a novel positive feedback loop in the rodent liver circadian clock. Mol. Endocrinol. 20 (2006) 1715-1727
    • (2006) Mol. Endocrinol. , vol.20 , pp. 1715-1727
    • Canaple, L.1
  • 77
    • 15944382729 scopus 로고    scopus 로고
    • CLOCK is involved in the circadian transactivation of peroxisome-proliferator-activated receptor α (PPARα) in mice
    • Oishi K., et al. CLOCK is involved in the circadian transactivation of peroxisome-proliferator-activated receptor α (PPARα) in mice. Biochem. J. 386 (2005) 575-581
    • (2005) Biochem. J. , vol.386 , pp. 575-581
    • Oishi, K.1
  • 78
    • 26944446214 scopus 로고    scopus 로고
    • CLOCK/BMAL1 is involved in lipid metabolism via transactivation of the peroxisome proliferator-activated receptor (PPAR) response element
    • Inoue I., et al. CLOCK/BMAL1 is involved in lipid metabolism via transactivation of the peroxisome proliferator-activated receptor (PPAR) response element. J. Atheroscler. Thromb. 12 (2005) 169-174
    • (2005) J. Atheroscler. Thromb. , vol.12 , pp. 169-174
    • Inoue, I.1
  • 79
    • 24744470282 scopus 로고    scopus 로고
    • Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis
    • Shimba S., et al. Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 12071-12076
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 12071-12076
    • Shimba, S.1
  • 80
    • 0035919479 scopus 로고    scopus 로고
    • Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors
    • Rutter J., et al. Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors. Science 293 (2001) 510-514
    • (2001) Science , vol.293 , pp. 510-514
    • Rutter, J.1
  • 81
    • 20844461135 scopus 로고    scopus 로고
    • Obesity and metabolic syndrome in circadian Clock mutant mice
    • Turek F.W., et al. Obesity and metabolic syndrome in circadian Clock mutant mice. Science 308 (2005) 1043-1045
    • (2005) Science , vol.308 , pp. 1043-1045
    • Turek, F.W.1
  • 82
    • 14044264801 scopus 로고    scopus 로고
    • BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis
    • Rudic R.D., et al. BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis. PLoS Biol. 2 (2004) e377
    • (2004) PLoS Biol. , vol.2
    • Rudic, R.D.1
  • 83
    • 33746603912 scopus 로고    scopus 로고
    • CLOCK is involved in obesity-induced disordered fibrinolysis in ob/ob mice by regulating PAI-1 gene expression
    • Oishi K., et al. CLOCK is involved in obesity-induced disordered fibrinolysis in ob/ob mice by regulating PAI-1 gene expression. J. Thromb. Haemost. 4 (2006) 1774-1780
    • (2006) J. Thromb. Haemost. , vol.4 , pp. 1774-1780
    • Oishi, K.1
  • 84
    • 29344452934 scopus 로고    scopus 로고
    • Disrupted fat absorption attenuates obesity induced by a high-fat diet in Clock mutant mice
    • Oishi K., et al. Disrupted fat absorption attenuates obesity induced by a high-fat diet in Clock mutant mice. FEBS Lett. 580 (2006) 127-130
    • (2006) FEBS Lett. , vol.580 , pp. 127-130
    • Oishi, K.1
  • 85
    • 17044396029 scopus 로고    scopus 로고
    • Progressive arthropathy in mice with a targeted disruption of the Mop3/Bmal-1 locus
    • Bunger M.K., et al. Progressive arthropathy in mice with a targeted disruption of the Mop3/Bmal-1 locus. Genesis 41 (2005) 122-132
    • (2005) Genesis , vol.41 , pp. 122-132
    • Bunger, M.K.1
  • 86
    • 23444431623 scopus 로고    scopus 로고
    • Retinoid x receptor heterodimers in the metabolic syndrome
    • Shulman A.I., and Mangelsdorf D.J. Retinoid x receptor heterodimers in the metabolic syndrome. N. Engl. J. Med. 353 (2005) 604-615
    • (2005) N. Engl. J. Med. , vol.353 , pp. 604-615
    • Shulman, A.I.1    Mangelsdorf, D.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.