Tyrosine residues at the carboxyl terminus of Vav1 play an important role in regulation of its biological activity

Journal of Biological Chemistry

Volumn 285, Issue 30, 2010, Pages 23075-23085

  Lazer, Galit ^a   Pe'er, Liron ^a   Farago, Marganit ^a   Machida, Kazuya ^b   Mayer, Bruce J ^b   Katzav, Shulamit ^a  

^a HEBREW UNIVERSITY   (Israel)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO TERMINUS; BIOLOGICAL ACTIVITIES; CARBOXYL TERMINUS; CARBOXYL-TERMINAL; GTPASE-ACTIVATING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEMATOPOIETIC SYSTEMS; HUMAN MALIGNANCIES; NFAT ACTIVITY; NUCLEAR FACTOR OF ACTIVATED T-CELLS; PANCREATIC CANCERS; PHOSPHOLIPASE C; SIGNAL TRANSDUCER PROTEINS; TYROSINE PHOSPHORYLATION; TYROSINE RESIDUES; WILD TYPES;

AMINO ACIDS; METADATA; PHOSPHATASES; PHOSPHORYLATION;

PROTEINS;

ABELSON KINASE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PHENYLALANINE; PHOSPHOLIPASE C GAMMA; PROTEIN SH2; PROTEIN SH3; PROTEIN SHC; PROTEIN TYROSINE KINASE; SIGNALING LYMPHOCYTE ACTIVATION MOLECULE ASSOCIATED PROTEIN; TRANSCRIPTION FACTOR NFAT; TYROSINE; UNCLASSIFIED DRUG; VAV1 PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL GROWTH; CONTROLLED STUDY; EMBRYO; GENE MUTATION; HUMAN; HUMAN CELL; MUTANT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CATTLE; CELL TRANSFORMATION, NEOPLASTIC; ENZYME ACTIVATION; HUMANS; JURKAT CELLS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NFATC TRANSCRIPTION FACTORS; PANCREATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-VAV; RATS; T-LYMPHOCYTES; TYROSINE;

EID: 77954934945     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.094508     Document Type: Article

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