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Volumn 47, Issue 2, 2008, Pages 668-676

Adenosine monophosphate-activated protein kinase modulates the activated phenotype of hepatic stellate cells

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ADIPONECTIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INITIATION FACTOR 4E BINDING PROTEIN 1; INTERLEUKIN 1; MAMMALIAN TARGET OF RAPAMYCIN; METFORMIN; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR; PROCOLLAGEN C PROTEINASE; PROTEIN KINASE B; S6 KINASE;

EID: 39549118017     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21995     Document Type: Article
Times cited : (123)

References (33)
  • 1
    • 0037129380 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002;346:1221-1231.
    • (2002) N Engl J Med , vol.346 , pp. 1221-1231
    • Angulo, P.1
  • 2
    • 33748111665 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Cyrokine-adipokine interplay and regulation of insulin resistance
    • Tilg H, Hotamisligil GS. Nonalcoholic fatty liver disease: cyrokine-adipokine interplay and regulation of insulin resistance. Gastroenterology 2006;131:934-945.
    • (2006) Gastroenterology , vol.131 , pp. 934-945
    • Tilg, H.1    Hotamisligil, G.S.2
  • 3
    • 30544439060 scopus 로고    scopus 로고
    • Therapy Insight: Adipocytokines in metabolic syndrome and related cardiovascular disease
    • Matsuzawa Y. Therapy Insight: adipocytokines in metabolic syndrome and related cardiovascular disease. Nat Clin Pract Cardiovasc Med 2006;3:35-42.
    • (2006) Nat Clin Pract Cardiovasc Med , vol.3 , pp. 35-42
    • Matsuzawa, Y.1
  • 4
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • Xu A, Wang Y, Keshaw H, Xu LY, Lam KS, Cooper GJ. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003;112:91-100.
    • (2003) J Clin Invest , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3    Xu, L.Y.4    Lam, K.S.5    Cooper, G.J.6
  • 5
    • 10744228583 scopus 로고    scopus 로고
    • Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin
    • Kamada Y, Tamura S, Kiso S, Matsumoto H, Saji Y, Yoshida Y, et al. Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin. Gastroenterology 2003;125:1796-1807.
    • (2003) Gastroenterology , vol.125 , pp. 1796-1807
    • Kamada, Y.1    Tamura, S.2    Kiso, S.3    Matsumoto, H.4    Saji, Y.5    Yoshida, Y.6
  • 6
    • 0037494960 scopus 로고    scopus 로고
    • Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
    • Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 2003;423:762-769.
    • (2003) Nature , vol.423 , pp. 762-769
    • Yamauchi, T.1    Kamon, J.2    Ito, Y.3    Tsuchida, A.4    Yokomizo, T.5    Kita, S.6
  • 7
    • 33644699965 scopus 로고    scopus 로고
    • The stimulatory effect of globular adiponectin on insulin-stimulated glucose uptake and fatty acid oxidation is impaired in skeletal muscle from obese subjects
    • Bruce CR, Merrz VA, Heigenhauser GJ, Dyck DJ. The stimulatory effect of globular adiponectin on insulin-stimulated glucose uptake and fatty acid oxidation is impaired in skeletal muscle from obese subjects. Diabetes 2005;54:3154-3160.
    • (2005) Diabetes , vol.54 , pp. 3154-3160
    • Bruce, C.R.1    Merrz, V.A.2    Heigenhauser, G.J.3    Dyck, D.J.4
  • 8
    • 0036851817 scopus 로고    scopus 로고
    • Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
    • Yamauchi T, Kamon J, Minokoshi Y, Ito Y, Waki H, Uchida S, et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 2002;8:1288-1295.
    • (2002) Nat Med , vol.8 , pp. 1288-1295
    • Yamauchi, T.1    Kamon, J.2    Minokoshi, Y.3    Ito, Y.4    Waki, H.5    Uchida, S.6
  • 9
    • 0344081177 scopus 로고    scopus 로고
    • Minireview: The AMP-activated protein kinase cascade: the key sensor of cellular energy status
    • Hardie DG. Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status. Endocrinology 2003;144:5179-5183.
    • (2003) Endocrinology , vol.144 , pp. 5179-5183
    • Hardie, D.G.1
  • 10
    • 0034773404 scopus 로고    scopus 로고
    • Role of AMP-activated protein kinase in mechanism of metformin action
    • Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, et al. Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 2001;108:1167-1174.
    • (2001) J Clin Invest , vol.108 , pp. 1167-1174
    • Zhou, G.1    Myers, R.2    Li, Y.3    Chen, Y.4    Shen, X.5    Fenyk-Melody, J.6
  • 11
    • 33847072201 scopus 로고    scopus 로고
    • AMP-activated protein kinase as a drug target
    • Hardie DG. AMP-activated protein kinase as a drug target. Annu Rev Pharmacol Toxicol 2007;47:185-210.
    • (2007) Annu Rev Pharmacol Toxicol , vol.47 , pp. 185-210
    • Hardie, D.G.1
  • 12
    • 15244356690 scopus 로고    scopus 로고
    • Mechanisms of disease: Mechanisms of hepatic fibrosis and therapeutic implications
    • Friedman SL. Mechanisms of disease: mechanisms of hepatic fibrosis and therapeutic implications. Nat Clin Pract Gastroenterol Hepatol 2004;1:98-105.
    • (2004) Nat Clin Pract Gastroenterol Hepatol , vol.1 , pp. 98-105
    • Friedman, S.L.1
  • 13
    • 19544378172 scopus 로고    scopus 로고
    • The roles of leptin and adiponectin: A novel paradigm in adipocytokine regulation of liver fibrosis and stellate cell biology
    • Ding X, Saxena NK, Lin S, Xu A, Srinivasan S, Anania FA. The roles of leptin and adiponectin: a novel paradigm in adipocytokine regulation of liver fibrosis and stellate cell biology. Am J Pathol 2005;166:1655-1669.
    • (2005) Am J Pathol , vol.166 , pp. 1655-1669
    • Ding, X.1    Saxena, N.K.2    Lin, S.3    Xu, A.4    Srinivasan, S.5    Anania, F.A.6
  • 14
    • 0027234054 scopus 로고
    • Regulation of extracellular matrix synthesis by transforming growth factor beta 1 in human fat-storing cells
    • Casini A, Pinzani M, Milani S, Grappone C, Galli G, Jezequel AM, Schuppan D, et al. Regulation of extracellular matrix synthesis by transforming growth factor beta 1 in human fat-storing cells. Gastroenrerology 1993;105:245-253.
    • (1993) Gastroenrerology , vol.105 , pp. 245-253
    • Casini, A.1    Pinzani, M.2    Milani, S.3    Grappone, C.4    Galli, G.5    Jezequel, A.M.6    Schuppan, D.7
  • 15
    • 0024840085 scopus 로고
    • Effects of platelet-derived growth factot and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells
    • Pinzani M, Gesualdo L, Sabbah GM, Abboud HE. Effects of platelet-derived growth factot and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells. J Clin Invest 1989;84:1786-1793.
    • (1989) J Clin Invest , vol.84 , pp. 1786-1793
    • Pinzani, M.1    Gesualdo, L.2    Sabbah, G.M.3    Abboud, H.E.4
  • 16
    • 0031004620 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is required for platelet-derived growth factor's actions on hepatic stellate cells
    • Marra F, Genrilini A, Pinzani M, Choudhury GG, Parola M, Herbst H, et al. Phosphatidylinositol 3-kinase is required for platelet-derived growth factor's actions on hepatic stellate cells. Gastroenterology 1997;112:1297-1306.
    • (1997) Gastroenterology , vol.112 , pp. 1297-1306
    • Marra, F.1    Genrilini, A.2    Pinzani, M.3    Choudhury, G.G.4    Parola, M.5    Herbst, H.6
  • 17
    • 34249887451 scopus 로고    scopus 로고
    • Resistin as an intrahepatic cyrokine: Overexpression during chronic injury and induction of proinflammatory actions in hepatic stellate cells
    • Bertolani C, Sancho-Bru P, Failli P, Bataller R, Aleffi S, DeFranco R, et al. Resistin as an intrahepatic cyrokine: overexpression during chronic injury and induction of proinflammatory actions in hepatic stellate cells. Am J Pathol 2006;169:2042-2053.
    • (2006) Am J Pathol , vol.169 , pp. 2042-2053
    • Bertolani, C.1    Sancho-Bru, P.2    Failli, P.3    Bataller, R.4    Aleffi, S.5    DeFranco, R.6
  • 18
    • 33746120376 scopus 로고    scopus 로고
    • Overexpression of Bcl-2 by activated human hepatic stellate cells: Resistance to apoptosis as a mechanism of progressive heparic fibrogenesis in humans
    • Novo E, Marra F, Zamara E, Valfre di Bonzo L, Monitillo L, Cannito S, et al. Overexpression of Bcl-2 by activated human hepatic stellate cells: resistance to apoptosis as a mechanism of progressive heparic fibrogenesis in humans. Gut 2006;55:1174-1182.
    • (2006) Gut , vol.55 , pp. 1174-1182
    • Novo, E.1    Marra, F.2    Zamara, E.3    Valfre di Bonzo, L.4    Monitillo, L.5    Cannito, S.6
  • 19
    • 15744403731 scopus 로고    scopus 로고
    • Binding of hepatitis C virus envelope prorein E2 to CD81 up-regulates matrix metalloproteinase-2 in human hepatic stellate cells
    • Mazzocca A, Sciammetta SC, Carloni V, Cosmi L, Annunziato F, Harada T, et al. Binding of hepatitis C virus envelope prorein E2 to CD81 up-regulates matrix metalloproteinase-2 in human hepatic stellate cells. J Biol Chem 2005;280:11329-11339.
    • (2005) J Biol Chem , vol.280 , pp. 11329-11339
    • Mazzocca, A.1    Sciammetta, S.C.2    Carloni, V.3    Cosmi, L.4    Annunziato, F.5    Harada, T.6
  • 20
    • 3042699353 scopus 로고    scopus 로고
    • Adiponectin protects LPS-induced liver injury through modulation of TNF-alpha in KK-Ay obese mice
    • Masaki T, Chiba S, Tatsukawa H, Yasuda T, Noguchi H, Seike M, et al. Adiponectin protects LPS-induced liver injury through modulation of TNF-alpha in KK-Ay obese mice. HEPATOLOGY 2004;40:177-184.
    • (2004) HEPATOLOGY , vol.40 , pp. 177-184
    • Masaki, T.1    Chiba, S.2    Tatsukawa, H.3    Yasuda, T.4    Noguchi, H.5    Seike, M.6
  • 21
    • 33847733103 scopus 로고    scopus 로고
    • Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions
    • Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, et al. Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions. Nat Med 2007;13:332-339.
    • (2007) Nat Med , vol.13 , pp. 332-339
    • Yamauchi, T.1    Nio, Y.2    Maki, T.3    Kobayashi, M.4    Takazawa, T.5    Iwabu, M.6
  • 22
    • 0032862560 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase activation differentially regulates platelet-derived growth factor's actions in hepatic stellate cells, and is induced by in vivo liver injury in the rat
    • Marra F, Arrighi MC, Fazi M, Caligiuri A, Pinzani M, Romanelli RG, et al. Extracellular signal-regulated kinase activation differentially regulates platelet-derived growth factor's actions in hepatic stellate cells, and is induced by in vivo liver injury in the rat. HEPATOLOGY 1999;30:951-958.
    • (1999) HEPATOLOGY , vol.30 , pp. 951-958
    • Marra, F.1    Arrighi, M.C.2    Fazi, M.3    Caligiuri, A.4    Pinzani, M.5    Romanelli, R.G.6
  • 23
    • 0036787934 scopus 로고    scopus 로고
    • Distinct cell cycle timing requirements for extracellular signal-regulated kinase and phosphoinositide 3-kinase signaling pathways in somatic cell mitosis
    • Roberts EC, Shapiro PS, Nahreini TS, Pages G, Pouyssegur J, Ahn NG. Distinct cell cycle timing requirements for extracellular signal-regulated kinase and phosphoinositide 3-kinase signaling pathways in somatic cell mitosis. Mol Cell Biol 2002;22:7226-7241.
    • (2002) Mol Cell Biol , vol.22 , pp. 7226-7241
    • Roberts, E.C.1    Shapiro, P.S.2    Nahreini, T.S.3    Pages, G.4    Pouyssegur, J.5    Ahn, N.G.6
  • 24
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • Wullschleger S, Loewith R, Hall MN. TOR signaling in growth and metabolism. Cell 2006;124:471-484.
    • (2006) Cell , vol.124 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 25
    • 33745196745 scopus 로고    scopus 로고
    • Activation of AMP-activated protein kinase in the liver: A new strategy for the management of metabolic hepatic disorders
    • Viollet B, Foretz M, Guigas B, Horman S, Dentin R, Bertrand L, et al. Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders. J Physiol 2006;574:41-53.
    • (2006) J Physiol , vol.574 , pp. 41-53
    • Viollet, B.1    Foretz, M.2    Guigas, B.3    Horman, S.4    Dentin, R.5    Bertrand, L.6
  • 26
    • 20844449238 scopus 로고    scopus 로고
    • AMP-activated prorein kinase induces a p53-dependent metabolic checkpoint
    • Jones RG, Plas DR, Kubek S, Buzzai M, Mu J, Xu Y, et al. AMP-activated prorein kinase induces a p53-dependent metabolic checkpoint. Mol Cell 2005;18:283-293.
    • (2005) Mol Cell , vol.18 , pp. 283-293
    • Jones, R.G.1    Plas, D.R.2    Kubek, S.3    Buzzai, M.4    Mu, J.5    Xu, Y.6
  • 27
    • 0037067666 scopus 로고    scopus 로고
    • The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways
    • Fryer LG, Parbu-Patel A, Carling D. The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways. J Biol Chem 2002;277:25226-25232.
    • (2002) J Biol Chem , vol.277 , pp. 25226-25232
    • Fryer, L.G.1    Parbu-Patel, A.2    Carling, D.3
  • 28
    • 33744976813 scopus 로고    scopus 로고
    • Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells
    • Hattori Y, Suzuki K, Hartori S, Kasai K. Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells. Hypertension 2006;47:1183-1188.
    • (2006) Hypertension , vol.47 , pp. 1183-1188
    • Hattori, Y.1    Suzuki, K.2    Hartori, S.3    Kasai, K.4
  • 30
    • 0028169447 scopus 로고
    • NF-kappa B and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene
    • Ueda A, Okuda K, Ohno S, Shirai A, Igarashi T, Matsunaga K, et al. NF-kappa B and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene. J Immunol 1994;153:2052-2063.
    • (1994) J Immunol , vol.153 , pp. 2052-2063
    • Ueda, A.1    Okuda, K.2    Ohno, S.3    Shirai, A.4    Igarashi, T.5    Matsunaga, K.6
  • 31
    • 33646077675 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3
    • King TD, Song L, Jope RS. AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3. Biochem Pharmacol 2006;71:1637-1647.
    • (2006) Biochem Pharmacol , vol.71 , pp. 1637-1647
    • King, T.D.1    Song, L.2    Jope, R.S.3
  • 32
    • 26844527037 scopus 로고    scopus 로고
    • Adenosine monophosphate-activated protein kinase suppresses vascular smooth muscle cell proliferation through the inhibition of cell cycle progression
    • Igata M, Motoshima H, Tsuruzoe K, Kojima K, Matsumuta T, Kondo T, et al. Adenosine monophosphate-activated protein kinase suppresses vascular smooth muscle cell proliferation through the inhibition of cell cycle progression. Circ Res 2005;97:837-844.
    • (2005) Circ Res , vol.97 , pp. 837-844
    • Igata, M.1    Motoshima, H.2    Tsuruzoe, K.3    Kojima, K.4    Matsumuta, T.5    Kondo, T.6
  • 33
    • 0345167800 scopus 로고    scopus 로고
    • TSC2 mediates cellular energy response to control cell growth and survival
    • Inoki K, Zhu T, Guan KL. TSC2 mediates cellular energy response to control cell growth and survival. Cell 2003;115:577-590.
    • (2003) Cell , vol.115 , pp. 577-590
    • Inoki, K.1    Zhu, T.2    Guan, K.L.3


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