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Volumn 20, Issue 2, 2010, Pages 114-122

Adenosine in fibrosis

Author keywords

Adenosine receptor; Cirrhosis; Collagen; Fibrosis

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 4 [2 [7 AMINO 2 (2 FURYL) 1,2,4 TRIAZOLO[2,3 A][1,3,5]TRIAZIN 5 YLAMINO]ETHYL]PHENOL; ADENOSINE; ADENOSINE A2 RECEPTOR ANTAGONIST; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR AGONIST; ADENOSINE A2A RECEPTOR ANTAGONIST; ADENOSINE A2B RECEPTOR ANTAGONIST; ADENOSINE A3 RECEPTOR; ADENOSINE DEAMINASE; COLLAGEN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 6; INTERLEUKIN 8; METHOTREXATE; MRE 0094; NUCLEOTIDASE; SALAZOSULFAPYRIDINE; SALICYLIC ACID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 77954760632     PISSN: 14397595     EISSN: 14397609     Source Type: Journal    
DOI: 10.1007/s10165-009-0251-4     Document Type: Review
Times cited : (40)

References (94)
  • 1
    • 84940815279 scopus 로고
    • The physiological activity of adenine compounds with special reference to their action upon the mammalian heart
    • Drury AN, Szent-Gyorgi A. The physiological activity of adenine compounds with special reference to their action upon the mammalian heart. J Physiol. 1929;68:213-37.
    • (1929) J Physiol , vol.68 , pp. 213-237
    • Drury, A.N.1    Szent-Gyorgi, A.2
  • 2
    • 0014699031 scopus 로고
    • The effect of adenosine and adenine nucleotides on the cyclic adenosine-3', 5'-phosphate content of Guinea pig cerebral cortex slices
    • Sattin A, Rall TW. The effect of adenosine and adenine nucleotides on the cyclic adenosine-3', 5'-phosphate content of guinea pig cerebral cortex slices. Mol Pharmacol. 1970;6:13-23.
    • (1970) Mol Pharmacol , vol.6 , pp. 13-23
    • Sattin, A.1    Rall, T.W.2
  • 3
    • 0028946706 scopus 로고
    • Adenosine receptor subtypes: Characterization and therapeutic regulation
    • Olah ME, Stiles GL. Adenosine receptor subtypes: characterization and therapeutic regulation. Ann Rev Pharmacol Toxicol. 1995;35:581-606.
    • (1995) Ann Rev Pharmacol Toxicol , vol.35 , pp. 581-606
    • Olah, M.E.1    Stiles, G.L.2
  • 5
    • 0001409645 scopus 로고    scopus 로고
    • Role of P1 receptors in inflammation
    • Abbracchio MP, Williams M, editors., vol 151/II: Purinergic and pyrimid-inergic signaling II. Cardiovascular respiratory, immune, metabolic and gastrointestinal tract function. Berlin: Springer
    • Montesinos MC, Cronstein BN. Role of P1 receptors in inflammation. In: Abbracchio MP, Williams M, editors. Handbook of experimental pharmacology, vol 151/II: Purinergic and pyrimid-inergic signaling II. Cardiovascular respiratory, immune, metabolic and gastrointestinal tract function. Berlin: Springer; 2001. p. 303-21.
    • (2001) Handbook of Experimental Pharmacology , pp. 303-321
    • Montesinos, M.C.1    Cronstein, B.N.2
  • 7
    • 0025135242 scopus 로고
    • Fcgamma receptor-mediated functions in neutrophils are modulated by adenosine receptor occupancy:A1 receptors are stimulatory and A2 receptors are inhibitory
    • Salmon JE, Cronstein BN. Fcgamma receptor-mediated functions in neutrophils are modulated by adenosine receptor occupancy:A1 receptors are stimulatory and A2 receptors are inhibitory. J Immunol. 1990;145:2235-40.
    • (1990) J Immunol , vol.145 , pp. 2235-2240
    • Salmon, J.E.1    Cronstein, B.N.2
  • 8
  • 9
    • 0030698058 scopus 로고    scopus 로고
    • Wound healing is accelerated by agonists of adenosine A2 (G alpha s-linked) receptors
    • Montesinos MC, Gadangi P, Longaker M, Sung J, Levine J, Nilsen D, et al. Wound healing is accelerated by agonists of adenosine A2 (G alpha s-linked) receptors. J Exp Med. 1997;186(9):1615-20.
    • (1997) J Exp Med , vol.186 , Issue.9 , pp. 1615-1620
    • Montesinos, M.C.1    Gadangi, P.2    Longaker, M.3    Sung, J.4    Levine, J.5    Nilsen, D.6
  • 10
    • 0036087210 scopus 로고    scopus 로고
    • Adenosine promotes wound healing and mediates angiogenesis in response to tissue injury via occupancy of A(2A) receptors
    • Montesinos MC, Desai A, Chen JF, Yee H, Schwarzschild MA, Fink JS, et al. Adenosine promotes wound healing and mediates angiogenesis in response to tissue injury via occupancy of A(2A) receptors. Am J Pathol. 2002;160(6):2009-18.
    • (2002) Am J Pathol , vol.160 , Issue.6 , pp. 2009-2018
    • Montesinos, M.C.1    Desai, A.2    Chen, J.F.3    Yee, H.4    Schwarzschild, M.A.5    Fink, J.S.6
  • 11
    • 0036130068 scopus 로고    scopus 로고
    • Aden-osine A2A receptor agonists promote more rapid wound healing than recombinant human platelet-derived growth factor (Beca-plermin gel)
    • Victor-Vega C, Desai A, Montesinos MC, Cronstein BN. Aden-osine A2A receptor agonists promote more rapid wound healing than recombinant human platelet-derived growth factor (Beca-plermin gel). Inflammation. 2002;26(1):19-24.
    • (2002) Inflammation , vol.26 , Issue.1 , pp. 19-24
    • Victor-Vega, C.1    Desai, A.2    Montesinos, M.C.3    Cronstein, B.N.4
  • 12
    • 0020554177 scopus 로고
    • Aden-osine: A physiological modulator of superoxide anion generation by human neutrophils
    • Cronstein BN, Kramer SB, Weissmann G, Hirschhorn R. Aden-osine: a physiological modulator of superoxide anion generation by human neutrophils. J Exp Med. 1983;158(4):1160-77.
    • (1983) J Exp Med , vol.158 , Issue.4 , pp. 1160-1177
    • Cronstein, B.N.1    Kramer, S.B.2    Weissmann, G.3    Hirschhorn, R.4
  • 13
    • 0022397930 scopus 로고
    • Adenosine; a physiologic modulator of superoxide anion generation by human neutrophils. Adenosine acts via an A2 receptor on human neutrophils
    • Cronstein BN, Rosenstein ED, Kramer SB, Weissmann G, Hirschhorn R. Adenosine; a physiologic modulator of superoxide anion generation by human neutrophils. Adenosine acts via an A2 receptor on human neutrophils. J Immunol. 1985;135(2):1366-71.
    • (1985) J Immunol , vol.135 , Issue.2 , pp. 1366-1371
    • Cronstein, B.N.1    Rosenstein, E.D.2    Kramer, S.B.3    Weissmann, G.4    Hirschhorn, R.5
  • 14
    • 0032589411 scopus 로고    scopus 로고
    • Neutrophil A2A adenosine receptor inhibits inflammation in a rat model of meningitis: Synergy with the type IV phosphodiesterase inhibitor, rolipram
    • Sullivan GW, Linden J, Buster BL, Scheld WM. Neutrophil A2A adenosine receptor inhibits inflammation in a rat model of meningitis: synergy with the type IV phosphodiesterase inhibitor, rolipram. J Infect Dis. 1999;180(5):1550-60.
    • (1999) J Infect Dis , vol.180 , Issue.5 , pp. 1550-1560
    • Sullivan, G.W.1    Linden, J.2    Buster, B.L.3    Scheld, W.M.4
  • 15
  • 16
    • 0026252463 scopus 로고
    • Potentiation of leukotriene B4-mediated inflammatory response by the adenosine antagonist, 8-phenyl theophylline
    • Rosengren S, Arfors KE, Proctor KG. Potentiation of leukotriene B4-mediated inflammatory response by the adenosine antagonist, 8-phenyl theophylline. Int J Microcirc Clin Exp. 1991;10:345-57.
    • (1991) Int J Microcirc Clin Exp , vol.10 , pp. 345-357
    • Rosengren, S.1    Arfors, K.E.2    Proctor, K.G.3
  • 17
    • 0035924320 scopus 로고    scopus 로고
    • Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage
    • Ohta A, Sitkovsky M. Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage. Nature. 2001;414(6866):916-20.
    • (2001) Nature , vol.414 , Issue.6866 , pp. 916-920
    • Ohta, A.1    Sitkovsky, M.2
  • 18
    • 0033190943 scopus 로고    scopus 로고
    • Selective A2A adenosine receptor activation reduces ischemia-reperfusion injury in rat kidney
    • Okusa MD, Linden J, Macdonald T, Huang L. Selective A2A adenosine receptor activation reduces ischemia-reperfusion injury in rat kidney. Am J Physiol. 1999;277(3 Pt 2):F404-12.
    • (1999) Am J Physiol , Issue.3 PART 2
    • Okusa, M.D.1    Linden, J.2    Macdonald, T.3    Huang, L.4
  • 22
    • 0026507232 scopus 로고
    • Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors
    • Cronstein BN, Levin RI, Philips MR, Hirschhorn R, Abramson SB, Weissmann G. Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors. J Immunol. 1992;148:2201-6.
    • (1992) J Immunol , vol.148 , pp. 2201-2206
    • Cronstein, B.N.1    Levin I, R.2    Philips, M.R.3    Hirschhorn, R.4    Abramson, S.B.5    Weissmann, G.6
  • 23
    • 0030878807 scopus 로고    scopus 로고
    • Role of A2a extracellular adenosine receptor-mediated signaling in adenosine-mediated inhibition of T-cell activation and expansion
    • Huang S, Apasov S, Koshiba M, Sitkovsky M. Role of A2a extracellular adenosine receptor-mediated signaling in adenosine-mediated inhibition of T-cell activation and expansion. Blood. 1997;90(4):1600-10.
    • (1997) Blood , vol.90 , Issue.4 , pp. 1600-1610
    • Huang, S.1    Apasov, S.2    Koshiba, M.3    Sitkovsky, M.4
  • 24
    • 0018165922 scopus 로고
    • Characterization of a specific adenosine receptor on human lymphocytes
    • Marone G, Plaut M, Lichtenstein LM. Characterization of a specific adenosine receptor on human lymphocytes. J Immunol. 1978;121:2153-9.
    • (1978) J Immunol , vol.121 , pp. 2153-2159
    • Marone, G.1    Plaut, M.2    Lichtenstein, L.M.3
  • 25
    • 0023851267 scopus 로고
    • Characterization of the human T lymphocyte adenosine receptor: Comparison of normal and systemic lupus erythematosus cells
    • Schultz LA, Kammer GM, Rudolph SA. Characterization of the human T lymphocyte adenosine receptor: comparison of normal and systemic lupus erythematosus cells. FASEB J. 1988;2:244-50.
    • (1988) FASEB J , vol.2 , pp. 244-250
    • Schultz, L.A.1    Kammer, G.M.2    Rudolph, S.A.3
  • 26
    • 0020597080 scopus 로고
    • Impaired immunoregulation in systemic lupus erythematosus: Defective adenosine-induced suppressor T lymphocyte generation
    • Kammer GM, Birch RE, Polmar SH. Impaired immunoregulation in systemic lupus erythematosus: defective adenosine-induced suppressor T lymphocyte generation. J Immunol. 1983;130: 1706-12.
    • (1983) J Immunol , vol.130 , pp. 1706-1712
    • Kammer, G.M.1    Birch, R.E.2    Polmar, S.H.3
  • 27
    • 0020444252 scopus 로고
    • Abnormal adenosine-induced immunosuppression and cAMP metabolism in T lymphocytes of patients with systemic lupus erythematosus
    • DOI 10.1073/pnas.79.23.7542
    • Mandler R, Birch RE, Polmar SH, Kammer GM, Rudolph SA. Abnormal adenosine-induced immunosuppression and cAMP metabolism in T lymphocytes of patients with systemic lupus erythematosus. Proc Natl Acad Sci USA. 1982;79:7542-6. (Pubitemid 13179143)
    • (1982) Proceedings of the National Academy of Sciences of the United States of America , vol.79 , Issue.23 , pp. 7542-7546
    • Mandler, R.1    Birch, R.E.2    Polmar, S.H.3
  • 28
    • 0031154752 scopus 로고    scopus 로고
    • Effects of extracellular ATP and adenosine on different thymocyte subsets. Possible role of ATP-gated channels and G protein-coupled pu-rinergic receptor
    • Apasov SG, Koshiba M, Chused TM, Sitkovsky MV. Effects of extracellular ATP and adenosine on different thymocyte subsets. Possible role of ATP-gated channels and G protein-coupled pu-rinergic receptor. J Immunol. 1997;158:5095-105.
    • (1997) J Immunol , vol.158 , pp. 5095-5105
    • Apasov, S.G.1    Koshiba, M.2    Chused, T.M.3    Sitkovsky, M.V.4
  • 29
    • 0031025034 scopus 로고    scopus 로고
    • Insights into thymic purine metabolism and adenosine deaminase deficiency revealed by transgenic mice overexpressing ecto-5'-nucleotidase (CD73)
    • Resta R, Hooker SW, Laurent AB, Jamshedur Rahman SM, Franklin M, Knudsen TB, et al. Insights into thymic purine metabolism and adenosine deaminase deficiency revealed by transgenic mice overexpressing ecto-5'-nucleotidase (CD73). J Clin Invest. 1997;99(4):676-83.
    • (1997) J Clin Invest , vol.99 , Issue.4 , pp. 676-683
    • Resta, R.1    Hooker, S.W.2    Laurent, A.B.3    Jamshedur, R.S.M.4    Franklin, M.5    Knudsen, T.B.6
  • 30
    • 0031586021 scopus 로고    scopus 로고
    • 2-Chloroadenosine stimulates granule exocytosis from mouse natural killer cells: Evidence for signal transduction through a novel extracellular receptor
    • Williams BA, Blay J, Hoskin DW. 2-Chloroadenosine stimulates granule exocytosis from mouse natural killer cells: evidence for signal transduction through a novel extracellular receptor. Exp Cell Res. 1997;233(1):187-97.
    • (1997) Exp Cell Res , vol.233 , Issue.1 , pp. 187-197
    • Williams, B.A.1    Blay, J.2    Hoskin, D.W.3
  • 31
    • 0028062055 scopus 로고
    • 2-Chloroadenosine inhibits the MHC-unrestricted cytolytic activity of anti-CD3-activated killer cells: Evidence for the involvement of a non- A1/A2 cell-surface adenosine receptor
    • Hoskin DW, Reynolds T, Blay J. 2-Chloroadenosine inhibits the MHC-unrestricted cytolytic activity of anti-CD3-activated killer cells: evidence for the involvement of a non- A1/A2 cell-surface adenosine receptor. Cell Immunol. 1994;159(1):85-93.
    • (1994) Cell Immunol , vol.159 , Issue.1 , pp. 85-93
    • Hoskin, D.W.1    Reynolds, T.2    Blay, J.3
  • 32
    • 0032586888 scopus 로고    scopus 로고
    • Patterns of A2A extracellular adenosine receptor expression in different functional subsets of human peripheral T cells. Flow cytometry studies with anti-A2A receptor monoclonal antibodies [In Process Citation]
    • Koshiba M, Rosin DL, Hayashi N, Linden J, Sitkovsky MV. Patterns of A2A extracellular adenosine receptor expression in different functional subsets of human peripheral T cells. Flow cytometry studies with anti-A2A receptor monoclonal antibodies [In Process Citation]. Mol Pharmacol. 1999;55(3):614-24.
    • (1999) Mol Pharmacol , vol.55 , Issue.3 , pp. 614-624
    • Koshiba, M.1    Rosin, D.L.2    Hayashi, N.3    Linden, J.4    Sitkovsky, M.V.5
  • 33
    • 0032178011 scopus 로고    scopus 로고
    • Extracellular purines and their receptors in immunoregulation. Review of recent advances
    • Sitkovsky MV. Extracellular purines and their receptors in immunoregulation. Review of recent advances. Nippon Ika Dai-gaku Zasshi. 1998;65(5):351-7.
    • (1998) Nippon Ika Dai-gaku Zasshi , vol.65 , Issue.5 , pp. 351-357
    • Sitkovsky, M.V.1
  • 34
    • 0030803163 scopus 로고    scopus 로고
    • Memory of extracellular adenosine A2A purinergic receptor-mediated signaling in murine T cells
    • Koshiba M, Kojima H, Huang S, Apasov S, Sitkovsky MV. Memory of extracellular adenosine A2A purinergic receptor-mediated signaling in murine T cells. J Biol Chem. 1997;272(41):25881-9.
    • (1997) J Biol Chem , vol.272 , Issue.41 , pp. 25881-25889
    • Koshiba, M.1    Kojima, H.2    Huang, S.3    Apasov, S.4    Sitkovsky, M.V.5
  • 35
    • 84989558482 scopus 로고
    • Suppression of lipopolysaccharide-stimulated release of tumor necrosis factor by adenosine: Evidence for A2 receptors on rat Kupffer cells
    • Reinstein LJ, Lichtman SN, Currin RT, Wang J, Thurman RG, Lemasters JJ, et al. Suppression of lipopolysaccharide-stimulated release of tumor necrosis factor by adenosine: evidence for A2 receptors on rat Kupffer cells. Hepatology. 1994;19(6):1445-52.
    • (1994) Hepatology , vol.19 , Issue.6 , pp. 1445-1452
    • Reinstein, L.J.1    Lichtman, S.N.2    Currin, R.T.3    Wang, J.4    Thurman, R.G.5    Lemasters, J.J.6
  • 36
    • 0030588630 scopus 로고    scopus 로고
    • Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice.
    • Hasko G, Szabo C, Nemeth ZH, Kvetan V, Pastores SM, Vizi ES. Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice. J Immunol. 1996;157(10):4634-40.
    • (1996) J Immunol , vol.157 , Issue.10 , pp. 4634-4640
    • Hasko, G.1    Szabo, C.2    Nemeth, Z.H.3    Kvetan, V.4    Pastores, S.M.5    Vizi, E.S.6
  • 37
    • 0029915543 scopus 로고    scopus 로고
    • Inhibition of TNF-alpha expression by adenosine: Role of A3 adenosine receptors
    • Sajjadi FG, Takabayashi K, Foster AC, Domingo RC, Firestein GS. Inhibition of TNF-alpha expression by adenosine: role of A3 adenosine receptors. J Immunol. 1996;156(9):3435-42.
    • (1996) J Immunol , vol.156 , Issue.9 , pp. 3435-3442
    • Sajjadi, F.G.1    Takabayashi, K.2    Foster, A.C.3    Domingo, R.C.4    Firestein, G.S.5
  • 38
    • 0031691973 scopus 로고    scopus 로고
    • Suppression of macrophage inflammatory protein (MIP)-1α production and collagen-induced arthritis by adenosine receptor agonists
    • DOI 10.1038/sj.bjp.0702040
    • Szabo C, Scott GS, Virag L, Egnaczyk G, Salzman AL, Shanley TP, et al. Suppression of macrophage inflammatory protein (MIP)-1α production and collagen-induced arthritis by adenosine receptor agonists. Br J Pharmacol. 1998;125(2):379-87. (Pubitemid 28425204)
    • (1998) British Journal of Pharmacology , vol.125 , Issue.2 , pp. 379-387
    • Szabo, C.1    Scott, G.S.2    Virag, L.3    Egnaczyk, G.4    Salzman, A.L.5    Shanley, T.P.6    Hasko, G.7
  • 39
    • 0033820684 scopus 로고    scopus 로고
    • Adenosine inhibits IL-12 and TNF-alpha production via adenosine A2a receptor-dependent and independent mechanisms [In Process Citation]
    • Hasko G, Kuhel DG, Chen JF, Schwarzschild MA, Deitch EA, Mabley JG, et al. Adenosine inhibits IL-12 and TNF-alpha production via adenosine A2a receptor-dependent and independent mechanisms [In Process Citation]. FASEB J. 2000;14(13):2065-74.
    • (2000) FASEB J , vol.14 , Issue.13 , pp. 2065-2074
    • Hasko, G.1    Kuhel, D.G.2    Chen, J.F.3    Schwarzschild, M.A.4    Deitch, E.A.5    Mabley, J.G.6
  • 40
    • 0035477981 scopus 로고    scopus 로고
    • Inflammatory cytokines regulate function and expression of adenosine A(2A) receptors in human monocytic THP-1 cells
    • Khoa ND, Montesinos MC, Reiss AB, Delano D, Awadallah N, Cronstein BN. Inflammatory cytokines regulate function and expression of adenosine A(2A) receptors in human monocytic THP-1 cells. J Immunol. 2001;167(7):4026-32.
    • (2001) J Immunol , vol.167 , Issue.7 , pp. 4026-4032
    • Khoa, N.D.1    Montesinos, M.C.2    Reiss, A.B.3    Delano, D.4    Awadallah, N.5    Cronstein, B.N.6
  • 41
    • 2942754121 scopus 로고    scopus 로고
    • Cutting edge: Physiologic attenuation of proinflammatory transcription by the Gs protein-coupled A2A adenosine receptor in vivo
    • Lukashev D, Ohta A, Apasov S, Chen JF, Sitkovsky M. Cutting edge: physiologic attenuation of proinflammatory transcription by the Gs protein-coupled A2A adenosine receptor in vivo. J Immunol. 2004;173(1):21-4.
    • (2004) J Immunol , vol.173 , Issue.1 , pp. 21-24
    • Lukashev, D.1    Ohta, A.2    Apasov, S.3    Chen, J.F.4    Sitkovsky, M.5
  • 42
    • 0035451439 scopus 로고    scopus 로고
    • Methotrexate suppresses nf-kappab activation through inhibition of ikappabalpha phosphorylation and degradation
    • Majumdar S, Aggarwal BB. Methotrexate suppresses nf-kappab activation through inhibition of ikappabalpha phosphorylation and degradation. J Immunol. 2001;167(5):2911-20.
    • (2001) J Immunol , vol.167 , Issue.5 , pp. 2911-2920
    • Majumdar, S.1    Aggarwal, B.B.2
  • 43
    • 0029896521 scopus 로고    scopus 로고
    • Inhibition of synoviocyte collagenase gene expression by adenosine receptor stimulation
    • Boyle DL, Sajjadi FG, Firestein GS. Inhibition of synoviocyte collagenase gene expression by adenosine receptor stimulation. Arthritis Rheum. 1996;39:923-30.
    • (1996) Arthritis Rheum , vol.39 , pp. 923-930
    • Boyle, D.L.1    Sajjadi, F.G.2    Firestein, G.S.3
  • 44
    • 0030478842 scopus 로고    scopus 로고
    • Spinal cord adenosine receptor stimulation in rats inhibits peripheral neutrophil accumulation. The role of W-methyl-D-aspartate receptors
    • Bong GW, Rosengren S, Firestein GS. Spinal cord adenosine receptor stimulation in rats inhibits peripheral neutrophil accumulation. The role of W-methyl-D-aspartate receptors. J Clin Invest. 1996;98:2779-85.
    • (1996) J Clin Invest , vol.98 , pp. 2779-2785
    • Bong, G.W.1    Rosengren, S.2    Firestein, G.S.3
  • 46
    • 0038603203 scopus 로고    scopus 로고
    • Adenosine affects expression of membrane molecules, cytokine and chemokine release, and the T-cell stimulatory capacity of human dendritic cells
    • Panther E, Corinti S, Idzko M, Herouy Y, Napp M, la Sala A, et al. Adenosine affects expression of membrane molecules, cytokine and chemokine release, and the T-cell stimulatory capacity of human dendritic cells. Blood. 2003;101(10): 3985-90.
    • (2003) Blood , vol.101 , Issue.10 , pp. 3985-3990
    • Panther, E.1    Corinti, S.2    Idzko, M.3    Herouy, Y.4    Napp, M.5    La, S.A.6
  • 47
    • 0033957489 scopus 로고    scopus 로고
    • Ligand-activation of the adenosine A2a receptors inhibits IL-12 production by human monocytes
    • Link AA, Kino T, Worth JA, McGuire JL, Crane ML, Chrousos GP, et al. Ligand-activation of the adenosine A2a receptors inhibits IL-12 production by human monocytes. J Immunol. 2000;164(1):436-42.
    • (2000) J Immunol , vol.164 , Issue.1 , pp. 436-442
    • Link, A.A.1    Kino, T.2    Worth, J.A.3    McGuire, J.L.4    Crane, M.L.5    Chrousos, G.P.6
  • 48
    • 20444373378 scopus 로고    scopus 로고
    • Activation of Th1 and Tc1 cell adenosine A2A receptors directly inhibits IL-2 secretion in vitro and IL-2-driven expansion in vivo
    • Erdmann AA, Gao ZG, Jung U, Foley J, Borenstein T, Jacobson KA, et al. Activation of Th1 and Tc1 cell adenosine A2A receptors directly inhibits IL-2 secretion in vitro and IL-2-driven expansion in vivo. Blood. 2005;105(12):4707-14.
    • (2005) Blood , vol.105 , Issue.12 , pp. 4707-4714
    • Erdmann, A.A.1    Gao, Z.G.2    Jung, U.3    Foley, J.4    Borenstein, T.5    Jacobson, K.A.6
  • 49
    • 0032984166 scopus 로고    scopus 로고
    • Immunomodulatory effects of pharmacological elevation of cyclic AMP in T lymphocytes proceed via a protein kinase A independent mechanism
    • Bryce PJ, Dascombe MJ, Hutchinson IV. Immunomodulatory effects of pharmacological elevation of cyclic AMP in T lymphocytes proceed via a protein kinase A independent mechanism. Immunopharmacology. 1999;41(2):139-46.
    • (1999) Immunopharmacology , vol.41 , Issue.2 , pp. 139-146
    • Bryce, P.J.1    Dascombe, M.J.2    Hutchinson, I.V.3
  • 50
    • 0030612493 scopus 로고    scopus 로고
    • Adenosine A1 receptor promotion of multinu-cleated giant cell formation by human monocytes: A mechanism for methotrexate-induced nodulosis in rheumatoid arthritis
    • Merrill JT, Shen C, Schreibman D, Coffey D, Zakharenko O, Fisher R, et al. Adenosine A1 receptor promotion of multinu-cleated giant cell formation by human monocytes: a mechanism for methotrexate-induced nodulosis in rheumatoid arthritis. Arthritis Rheum. 1997;40:1308-15.
    • (1997) Arthritis Rheum , vol.40 , pp. 1308-1315
    • Merrill, J.T.1    Shen, C.2    Schreibman, D.3    Coffey, D.4    Zakharenko, O.5    Fisher, R.6
  • 53
    • 0042388120 scopus 로고    scopus 로고
    • Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway
    • Blackburn MR, Lee CG, Young HW, Zhu Z, Chunn JL, Kang MJ, et al. Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway. J Clin Invest. 2003;112(3):332-44.
    • (2003) J Clin Invest , vol.112 , Issue.3 , pp. 332-344
    • Blackburn, M.R.1    Lee, C.G.2    Young, H.W.3    Zhu, Z.4    Chunn, J.L.5    Kang, M.J.6
  • 54
    • 33646407318 scopus 로고    scopus 로고
    • Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis
    • Ma B, Blackburn MR, Lee CG, Homer RJ, Liu W, Flavell RA, et al. Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis. J Clin Invest. 2006;116(5):1274-83.
    • (2006) J Clin Invest , vol.116 , Issue.5 , pp. 1274-1283
    • Ma, B.1    Blackburn, M.R.2    Lee, C.G.3    Homer, R.J.4    Liu, W.5    Flavell, R.A.6
  • 55
    • 33646074537 scopus 로고    scopus 로고
    • Ecto-5'-nucleotidase (CD73)-mediated adenosine production is tissue protective in a model of bleomycin-induced lung injury
    • Volmer JB, Thompson LF, Blackburn MR. Ecto-5'-nucleotidase (CD73)-mediated adenosine production is tissue protective in a model of bleomycin-induced lung injury. J Immunol. 2006; 176(7):4449-58.
    • (2006) J Immunol , vol.176 , Issue.7 , pp. 4449-4458
    • Volmer, J.B.1    Thompson, L.F.2    Blackburn, M.R.3
  • 56
    • 0036787916 scopus 로고    scopus 로고
    • Interaction of IL-13 and C10 in the pathogenesis of bleomycin-induced pulmonary fibrosis
    • Belperio JA, Dy M, Burdick MD, Xue YY, Li K, Elias JA, et al. Interaction of IL-13 and C10 in the pathogenesis of bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol. 2002;27(4):419-27.
    • (2002) Am J Respir Cell Mol Biol , vol.27 , Issue.4 , pp. 419-427
    • Belperio, J.A.1    Dy, M.2    Burdick, M.D.3    Xue, Y.Y.4    Li, K.5    Elias, J.A.6
  • 57
    • 0033560126 scopus 로고    scopus 로고
    • Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
    • Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, et al. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest. 1999;103(6):779-88.
    • (1999) J Clin Invest , vol.103 , Issue.6 , pp. 779-788
    • Zhu, Z.1    Homer, R.J.2    Wang, Z.3    Chen, Q.4    Geba, G.P.5    Wang, J.6
  • 59
    • 0032697042 scopus 로고    scopus 로고
    • An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response
    • Chiaramonte MG, Donaldson DD, Cheever AW, Wynn TA. An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response. J Clin Invest. 1999;104(6):777-85.
    • (1999) J Clin Invest , vol.104 , Issue.6 , pp. 777-785
    • Chiaramonte, M.G.1    Donaldson, D.D.2    Cheever, A.W.3    Wynn, T.A.4
  • 60
    • 22544450731 scopus 로고    scopus 로고
    • Adenosine-dependent pulmonary fibrosis in adenosine deami-nase-deficient mice
    • Chunn JL, Molina JG, Mi T, Xia Y, Kellems RE, Blackburn MR. Adenosine-dependent pulmonary fibrosis in adenosine deami-nase-deficient mice. J Immunol. 2005;175(3):1937-46.
    • (2005) J Immunol , vol.175 , Issue.3 , pp. 1937-1946
    • Chunn, J.L.1    Molina, J.G.2    Mi, T.3    Xia, Y.4    Kellems, R.E.5    Blackburn, M.R.6
  • 61
    • 44849122917 scopus 로고    scopus 로고
    • Pharmacological blockade of A2A receptors prevents dermal fibrosis in a model of elevated tissue adenosine
    • Fernandez P, Trzaska S, Wilder T, Chiriboga L, Blackburn MR, Cronstein BN, et al. Pharmacological blockade of A2A receptors prevents dermal fibrosis in a model of elevated tissue adenosine. Am J Pathol. 2008;172(6):1675-82.
    • (2008) Am J Pathol , vol.172 , Issue.6 , pp. 1675-1682
    • Fernandez, P.1    Trzaska, S.2    Wilder, T.3    Chiriboga, L.4    Blackburn, M.R.5    Cronstein, B.N.6
  • 62
    • 0034644735 scopus 로고    scopus 로고
    • The use of enzyme therapy to regulate the metabolic and phenotypic consequences of adenosine deaminase deficiency in mice. Differential impact on pulmonary and immunologic abnormalities
    • Blackburn MR, Aldrich M, Volmer JB, Chen W, Zhong H, Kelly S, et al. The use of enzyme therapy to regulate the metabolic and phenotypic consequences of adenosine deaminase deficiency in mice. Differential impact on pulmonary and immunologic abnormalities. J Biol Chem. 2000;275(41):32114-21.
    • (2000) J Biol Chem , vol.275 , Issue.41 , pp. 32114-32121
    • Blackburn, M.R.1    Aldrich, M.2    Volmer, J.B.3    Chen, W.4    Zhong, H.5    Kelly, S.6
  • 63
    • 0035887625 scopus 로고    scopus 로고
    • Adenosine-dependent airway inflammation and hyperre-sponsiveness in partially adenosine deaminase-deficient mice
    • Chunn JL, Young HW, Baneijee SK, Colasurdo GN, Blackburn MR. Adenosine-dependent airway inflammation and hyperre-sponsiveness in partially adenosine deaminase-deficient mice. J Immunol. 2001;167(8):4676-85.
    • (2001) J Immunol , vol.167 , Issue.8 , pp. 4676-4685
    • Chunn, J.L.1    Young, H.W.2    Baneijee, S.K.3    Colasurdo, G.N.4    Blackburn, M.R.5
  • 65
  • 66
    • 0038128250 scopus 로고    scopus 로고
    • Ecto 5'-nucleotidase and nonspecific alkaline phosphatase. Two AMP-hydrolyzing ectoenzymes with distinct roles in human airways
    • Picher M, Burch LH, Hirsh AJ, Spychala J, Boucher RC. Ecto 5'-nucleotidase and nonspecific alkaline phosphatase. Two AMP-hydrolyzing ectoenzymes with distinct roles in human airways. J Biol Chem. 2003;278(15):13468-79.
    • (2003) J Biol Chem , vol.278 , Issue.15 , pp. 13468-13479
    • Picher, M.1    Burch, L.H.2    Hirsh, A.J.3    Spychala, J.4    Boucher, R.C.5
  • 67
    • 0018827215 scopus 로고
    • Enzymatic characterization of the matrix vesicle alkaline phosphatase isolated from bovine fetal epiphyseal cartilage
    • Fortuna R, Anderson HC, Carty RP, Sajdera SW. Enzymatic characterization of the matrix vesicle alkaline phosphatase isolated from bovine fetal epiphyseal cartilage. Calcif Tissue Int. 1980;30(3):217-25.
    • (1980) Calcif Tissue Int , vol.30 , Issue.3 , pp. 217-225
    • Fortuna, R.1    Anderson, H.C.2    Carty, R.P.3    Sajdera, S.W.4
  • 68
    • 11144230939 scopus 로고    scopus 로고
    • Synergy between A2B adenosine receptors and hypoxia in activating human lung fibroblasts
    • Zhong H, Belardinelli L, Maa T, Zeng D. Synergy between A2B adenosine receptors and hypoxia in activating human lung fibroblasts. Am J Respir Cell Mol Biol. 2005;32(1):2-8.
    • (2005) Am J Respir Cell Mol Biol , vol.32 , Issue.1 , pp. 2-8
    • Zhong, H.1    Belardinelli, L.2    Maa, T.3    Zeng, D.4
  • 69
    • 33746666617 scopus 로고    scopus 로고
    • Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury
    • Sun CX, Zhong H, Mohsenin A, Morschl E, Chunn JL, Molina JG, et al. Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury. J Clin Invest. 2006;116(8):2173-82.
    • (2006) J Clin Invest , vol.116 , Issue.8 , pp. 2173-2182
    • Sun, C.X.1    Zhong, H.2    Mohsenin, A.3    Morschl, E.4    Chunn, J.L.5    Molina, J.G.6
  • 71
    • 0035985787 scopus 로고    scopus 로고
    • Molecular action of methotrexate in inflammatory diseases
    • Chan ES, Cronstein BN. Molecular action of methotrexate in inflammatory diseases. Arthritis Res. 2002;4(4):266-73.
    • (2002) Arthritis Res , vol.4 , Issue.4 , pp. 266-273
    • Chan, E.S.1    Cronstein, B.N.2
  • 72
    • 22944470530 scopus 로고    scopus 로고
    • Low-dose methotrexate: A mainstay in the treatment of rheumatoid arthritis
    • Cronstein BN. Low-dose methotrexate: a mainstay in the treatment of rheumatoid arthritis. Pharmacol Rev. 2005;57(2):163-72.
    • (2005) Pharmacol Rev , vol.57 , Issue.2 , pp. 163-172
    • Cronstein, B.N.1
  • 73
    • 0025080436 scopus 로고
    • Ethanol increases extracellular adenosine by inhibiting adenosine uptake via the nucleoside transporter
    • Nagy LE, Diamond I, Casso DJ, Franklin C, Gordon AS. Ethanol increases extracellular adenosine by inhibiting adenosine uptake via the nucleoside transporter. J Biol Chem. 1990;265(4): 1946-51.
    • (1990) J Biol Chem , vol.265 , Issue.4 , pp. 1946-1951
    • Nagy, L.E.1    Diamond, I.2    Casso, D.J.3    Franklin, C.4    Gordon, A.S.5
  • 74
    • 0021174629 scopus 로고
    • Ethanol-induced activation of adenine nucleo-tide turnover. Evidence for a role of acetate
    • Puig JG, Fox IH. Ethanol-induced activation of adenine nucleo-tide turnover. Evidence for a role of acetate. J Clin Invest. 1984;74(3):936-41.
    • (1984) J Clin Invest , vol.74 , Issue.3 , pp. 936-941
    • Puig, J.G.1    Fox, I.H.2
  • 75
    • 0142122418 scopus 로고    scopus 로고
    • Caffeine reduces hypnotic effects of alcohol through aden-osine A2A receptor blockade
    • El Yacoubi M, Ledent C, Parmentier M, Costentin J, Vaugeois JM. Caffeine reduces hypnotic effects of alcohol through aden-osine A2A receptor blockade. Neuropharmacology. 2003;45(7): 977-85.
    • (2003) Neuropharmacology , vol.45 , Issue.7 , pp. 977-985
    • El Yacoubi, M.1    Ledent, C.2    Parmentier, M.3    Costentin, J.4    Vaugeois, J.M.5
  • 76
    • 0027092660 scopus 로고
    • Alcohol, smoking, coffee, and cirrhosis
    • Klatsky AL, Armstrong MA. Alcohol, smoking, coffee, and cirrhosis. Am J Epidemiol. 1992;136(10):1248-57.
    • (1992) Am J Epidemiol , vol.136 , Issue.10 , pp. 1248-1257
    • Klatsky, A.L.1    Armstrong, M.A.2
  • 79
    • 56349107309 scopus 로고    scopus 로고
    • Hepatic fibrosis-overview
    • Friedman SL. Hepatic fibrosis-overview. Toxicology. 2008;254(3): 120-9.
    • (2008) Toxicology , vol.254 , Issue.3 , pp. 120-129
    • Friedman, S.L.1
  • 80
    • 42949163491 scopus 로고    scopus 로고
    • Mechanisms of hepatic fibrogenesis
    • Friedman SL. Mechanisms of hepatic fibrogenesis. Gastroenterology. 2008;134(6):1655-69.
    • (2008) Gastroenterology , vol.134 , Issue.6 , pp. 1655-1669
    • Friedman, S.L.1
  • 81
    • 35948954244 scopus 로고    scopus 로고
    • Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver
    • Friedman SL. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev. 2008;88(1):125-72.
    • (2008) Physiol Rev , vol.88 , Issue.1 , pp. 125-172
    • Friedman, S.L.1
  • 82
    • 33747087250 scopus 로고    scopus 로고
    • Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis
    • Chan ES, Montesinos MC, Fernandez P, Desai A, Delano DL, Yee H, et al. Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis. Br J Pharmacol. 2006;148(8):1144-55.
    • (2006) Br J Pharmacol , vol.148 , Issue.8 , pp. 1144-1155
    • Chan, E.S.1    Montesinos, M.C.2    Fernandez, P.3    Desai, A.4    Delano, D.L.5    Yee, H.6
  • 84
    • 58949088374 scopus 로고    scopus 로고
    • Adenosine induces loss of actin stress fibers and inhibits contraction in hepatic stellate cells via Rho inhibition
    • Sohail MA, Hashmi AZ, Hakim W, Watanabe A, Zipprich A, Groszmann RJ, et al. Adenosine induces loss of actin stress fibers and inhibits contraction in hepatic stellate cells via Rho inhibition. Hepatology. 2009;49(1):185-94.
    • (2009) Hepatology , vol.49 , Issue.1 , pp. 185-194
    • Sohail, M.A.1    Hashmi, A.Z.2    Hakim, W.3    Watanabe, A.4    Zipprich, A.5    Groszmann, R.J.6
  • 85
    • 0034813705 scopus 로고    scopus 로고
    • Adenosine reverses a preestablished CCl4-induced micronodular cirrhosis through enhancing collagenolytic activity and stimulating hepatocyte cell proliferation in rats
    • Hernandez-Munoz R, Diaz-Munoz M, Suarez-Cuenca JA, Trejo-Solis C, Lopez V, Sanchez-Sevilla L, et al. Adenosine reverses a preestablished CCl4-induced micronodular cirrhosis through enhancing collagenolytic activity and stimulating hepatocyte cell proliferation in rats. Hepatology. 2001;34(4 Pt 1):677-87.
    • (2001) Hepatology , vol.34 , Issue.4 PART 1 , pp. 677-687
    • Hernandez-Munoz, R.1    Diaz-Munoz, M.2    Suarez-Cuenca, J.A.3    Trejo-Solis, C.4    Lopez, V.5    Sanchez-Sevilla, L.6
  • 86
    • 36348939367 scopus 로고    scopus 로고
    • Adenosine A2A receptor occupancy stimulates collagen expression by hepatic stellate cells via pathways involving protein kinase A, Src, and extracellular signal-regulated kinases 1/2 signaling cascade or p38 mitogen-activated protein kinase signaling pathway
    • Che J, Chan ES, Cronstein BN. Adenosine A2A receptor occupancy stimulates collagen expression by hepatic stellate cells via pathways involving protein kinase A, Src, and extracellular signal-regulated kinases 1/2 signaling cascade or p38 mitogen-activated protein kinase signaling pathway. Mol Pharmacol. 2007;72(6):1626-36.
    • (2007) Mol Pharmacol , vol.72 , Issue.6 , pp. 1626-1636
    • Che, J.1    Chan, E.S.2    Cronstein, B.N.3
  • 87
    • 33746968120 scopus 로고    scopus 로고
    • Adenosine A2A receptors in diffuse dermal fibrosis: Pathogenic role in human dermal fibroblasts and in a murine model of scleroderma
    • Chan ES, Fernandez P, Merchant AA, Montesinos MC, Trzaska S, Desai A, et al. Adenosine A2A receptors in diffuse dermal fibrosis: pathogenic role in human dermal fibroblasts and in a murine model of scleroderma. Arthritis Rheum. 2006;54(8): 2632-42.
    • (2006) Arthritis Rheum , vol.54 , Issue.8 , pp. 2632-2642
    • Chan, E.S.1    Fernandez, P.2    Merchant, A.A.3    Montesinos, M.C.4    Trzaska, S.5    Desai, A.6
  • 88
    • 53249091925 scopus 로고    scopus 로고
    • Adenosine A2A receptor blockade or deletion diminishes fibrocyte accumulation in the skin in a murine model of scleroderma, bleomycin-induced fibrosis
    • Katebi M, Fernandez P, Chan ES, Cronstein BN. Adenosine A2A receptor blockade or deletion diminishes fibrocyte accumulation in the skin in a murine model of scleroderma, bleomycin-induced fibrosis. Inflammation. 2008;31(5):299-303.
    • (2008) Inflammation , vol.31 , Issue.5 , pp. 299-303
    • Katebi, M.1    Fernandez, P.2    Chan, E.S.3    Cronstein, B.N.4
  • 89
    • 0030869159 scopus 로고    scopus 로고
    • Exogenous and endogenous adenosine inhibits fetal calf serum-induced growth of rat cardiac fibroblasts: Role of A2B receptors
    • Dubey RK, Gillespie DG, Mi Z, Jackson EK. Exogenous and endogenous adenosine inhibits fetal calf serum-induced growth of rat cardiac fibroblasts: role of A2B receptors. Circulation. 1997;96(8):2656-66.
    • (1997) Circulation , vol.96 , Issue.8 , pp. 2656-2666
    • Dubey, R.K.1    Gillespie, D.G.2    Mi, Z.3    Jackson, E.K.4
  • 90
    • 0033958349 scopus 로고    scopus 로고
    • A(2B) receptors mediate antimitogenesis in vascular smooth muscle cells
    • Dubey RK, Gillespie DG, Shue H, Jackson EK. A(2B) receptors mediate antimitogenesis in vascular smooth muscle cells. Hypertension. 2000;35(1 Pt 2):267-72.
    • (2000) Hypertension , vol.35 , Issue.1 PART 2 , pp. 267-272
    • Dubey, R.K.1    Gillespie, D.G.2    Shue, H.3    Jackson, E.K.4
  • 92
    • 0031924266 scopus 로고    scopus 로고
    • Adenosine inhibits collagen and protein synthesis in cardiac fibroblasts: Role of A2B receptors
    • Dubey RK, Gillespie DG, Jackson EK. Adenosine inhibits collagen and protein synthesis in cardiac fibroblasts: role of A2B receptors. Hypertension. 1998;31(4):943-8.
    • (1998) Hypertension , vol.31 , Issue.4 , pp. 943-948
    • Dubey, R.K.1    Gillespie, D.G.2    Jackson, E.K.3
  • 93
    • 33750510494 scopus 로고    scopus 로고
    • Long-term stimulation of adenosine A2b receptors begun after myocardial infarction prevents cardiac remodeling in rats
    • Wakeno M, Minamino T, Seguchi O, Okazaki H, Tsukamoto O, Okada K, et al. Long-term stimulation of adenosine A2b receptors begun after myocardial infarction prevents cardiac remodeling in rats. Circulation. 2006;114(18):1923-32.
    • (2006) Circulation , vol.114 , Issue.18 , pp. 1923-1932
    • Wakeno, M.1    Minamino, T.2    Seguchi, O.3    Okazaki, H.4    Tsukamoto, O.5    Okada, K.6
  • 94
    • 41849134386 scopus 로고    scopus 로고
    • Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling
    • Mi T, Abbasi S, Zhang H, Uray K, Chunn JL, Xia LW, et al. Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling. J Clin Invest. 2008;118(4):1491-501.
    • (2008) J Clin Invest , vol.118 , Issue.4 , pp. 1491-1501
    • Mi, T.1    Abbasi, S.2    Zhang, H.3    Uray, K.4    Chunn, J.L.5    Xia, L.W.6


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