Adenosine A1 receptor promotion of multinucleated giant cell formation by human monocytes: A mechanism for methotrexate-induced nodulosis in rheumatoid arthritis

Arthritis and Rheumatism

Volumn 40, Issue 7, 1997, Pages 1308-1315

  Merrill, Joan T ^a   Shen, Christine ^a   Schreibman, David ^b   Coffey, Dan ^a   Zakharenko, Olga ^a   Fisher, Robert ^a   Lahita, Robert G ^a   Salmon, Jane ^c   Cronstein, Bruce N ^b  

^a ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,7 DIMETHYL 1 PROPARGYLXANTHINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2 RECEPTOR ANTAGONIST; METHOTREXATE; PHORBOL 13 ACETATE 12 MYRISTATE; 1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE; 3,7-DIMETHYL-1-PROPARGYLXANTHINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE RECEPTOR; ANTIRHEUMATIC AGENT; DRUG DERIVATIVE; N(6) CYCLOPENTYLADENOSINE; N(6)-CYCLOPENTYLADENOSINE; THEOBROMINE; XANTHINE DERIVATIVE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL DIFFERENTIATION; CELL FUSION; CELL PROLIFERATION; CONTROLLED STUDY; FLOW CYTOMETRY; GENE EXPRESSION; GIANT CELL; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; RHEUMATOID NODULE; SYNCYTIUM; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; PATHOLOGY; PHYSIOLOGY;

ADENOSINE; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; CELLS, CULTURED; HUMANS; METHOTREXATE; MONOCYTES; RECEPTORS, PURINERGIC P1; RHEUMATOID NODULE; TETRADECANOYLPHORBOL ACETATE; THEOBROMINE; XANTHINES;

EID: 0030612493     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.16     Document Type: Article

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