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Volumn 176, Issue 7, 2006, Pages 4449-4458

Ecto-5′-nucleotidase (CD73)-mediated adenosine production is tissue protective in a model of bleomycin-induced lung injury

Author keywords

[No Author keywords available]

Indexed keywords

5' NUCLEOTIDASE; ADENINE NUCLEOTIDE DERIVATIVE; ADENOSINE; BLEOMYCIN; ECTO 5' NUCLEOTIDASE; ADENOSINE KINASE; COLLAGEN; NUCLEOTIDASE;

EID: 33646074537     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.176.7.4449     Document Type: Article
Times cited : (106)

References (58)
  • 1
    • 0033801235 scopus 로고    scopus 로고
    • High adenosine plasma concentration as a prognostic index for outcome in patients with septic shock
    • Martin, C., M. Leone, X. Viviand, M. L. Ayem, and R. Guieu. 2000. High adenosine plasma concentration as a prognostic index for outcome in patients with septic shock. Crit. Care Med. 28: 3198-3202.
    • (2000) Crit. Care Med. , vol.28 , pp. 3198-3202
    • Martin, C.1    Leone, M.2    Viviand, X.3    Ayem, M.L.4    Guieu, R.5
  • 2
    • 0000641688 scopus 로고
    • Brain adenosine concentration during hypoxia in rats
    • Winn, H. R., R. Rubio, and R. M. Berne. 1981. Brain adenosine concentration during hypoxia in rats. Am. J. Physiol. 241: H235-H242.
    • (1981) Am. J. Physiol. , vol.241
    • Winn, H.R.1    Rubio, R.2    Berne, R.M.3
  • 3
    • 0034332966 scopus 로고    scopus 로고
    • Ischemic-like condition releases norepinephrine and purines from different sources in superfused rat spleen strips
    • Sperlagh, B., M. Doda, M. Baranyi, and G. Hasko. 2000. Ischemic-like condition releases norepinephrine and purines from different sources in superfused rat spleen strips. J. Neuroimmunol. 111: 45-54.
    • (2000) J. Neuroimmunol. , vol.111 , pp. 45-54
    • Sperlagh, B.1    Doda, M.2    Baranyi, M.3    Hasko, G.4
  • 4
    • 0035040532 scopus 로고    scopus 로고
    • Molecular approach to adenosine receptors: Receptor-mediated mechanisms of tissue protection
    • Linden, J. 2001. Molecular approach to adenosine receptors: receptor-mediated mechanisms of tissue protection. Annu. Rev. Pharmacol. Toxicol. 41: 775-787.
    • (2001) Annu. Rev. Pharmacol. Toxicol. , vol.41 , pp. 775-787
    • Linden, J.1
  • 5
    • 0348222661 scopus 로고    scopus 로고
    • Adenosine: An endogenous regulator of innate immunity
    • Hasko, G., and B. N. Cronstein. 2004. Adenosine: an endogenous regulator of innate immunity. Trends Immunol. 25: 33-39.
    • (2004) Trends Immunol. , vol.25 , pp. 33-39
    • Hasko, G.1    Cronstein, B.N.2
  • 6
    • 0037305002 scopus 로고    scopus 로고
    • Too much of a good thing: Adenosine overload in adenosine-deaminase- deficient mice
    • Blackburn, M. R. 2003. Too much of a good thing: adenosine overload in adenosine-deaminase-deficient mice. Trends Pharmacol. Sci. 24: 66-70.
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 66-70
    • Blackburn, M.R.1
  • 7
    • 0342980932 scopus 로고    scopus 로고
    • Increase in plasma adenosine during brain ischemia in man: A study during transient ischemic attacks, and stroke
    • Laghi Pasini, F., F. Guideri, E. Picano, G. Parenti, C. Petersen, A. Varga, and T. Di Perri. 2000. Increase in plasma adenosine during brain ischemia in man: a study during transient ischemic attacks, and stroke. Brain Res. Bull. 51: 327-330.
    • (2000) Brain Res. Bull. , vol.51 , pp. 327-330
    • Laghi Pasini, F.1    Guideri, F.2    Picano, E.3    Parenti, G.4    Petersen, C.5    Varga, A.6    Di Perri, T.7
  • 8
    • 1642579653 scopus 로고    scopus 로고
    • Protection from ischemic liver injury by activation of A2A adenosine receptors during reperfusion: Inhibition of chemokine induction
    • Day, Y. J., M. A. Marshall, L. Huang, M. J. McDuffie, M. D. Okusa, and J. Linden. 2004. Protection from ischemic liver injury by activation of A2A adenosine receptors during reperfusion: inhibition of chemokine induction. Am. J. Physiol. Gastrointest. Liver Physiol. 286: G285-G293.
    • (2004) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.286
    • Day, Y.J.1    Marshall, M.A.2    Huang, L.3    McDuffie, M.J.4    Okusa, M.D.5    Linden, J.6
  • 9
    • 0035924320 scopus 로고    scopus 로고
    • Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage
    • Ohta, A., and M. Sitkovsky. 2001. Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage. Nature 414: 916-920.
    • (2001) Nature , vol.414 , pp. 916-920
    • Ohta, A.1    Sitkovsky, M.2
  • 10
    • 0017801449 scopus 로고
    • Potentiation of mast cell mediator release by adenosine
    • Marquardt, D. L., C. W. Parker, and T. J. Sullivan. 1978. Potentiation of mast cell mediator release by adenosine. J. Immunol. 120: 871-878.
    • (1978) J. Immunol. , vol.120 , pp. 871-878
    • Marquardt, D.L.1    Parker, C.W.2    Sullivan, T.J.3
  • 11
    • 0020655642 scopus 로고
    • Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects
    • Cushley, M. J., A. E. Tattersfield, and S. T. Holgate. 1983. Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. Br. J. Clin. Pharmacol. 15: 161-165.
    • (1983) Br. J. Clin. Pharmacol. , vol.15 , pp. 161-165
    • Cushley, M.J.1    Tattersfield, A.E.2    Holgate, S.T.3
  • 12
    • 7044247188 scopus 로고    scopus 로고
    • Selective inactivation or reconstitution of adenosine A2A receptors in bone marrow cells reveals their significant contribution to the development of ischemic brain injury
    • Yu, L., Z. Huang, J. Mariani, Y. Wang, M. Moskowitz, and J. F. Chen. 2004. Selective inactivation or reconstitution of adenosine A2A receptors in bone marrow cells reveals their significant contribution to the development of ischemic brain injury. Nat. Med. 10: 1081-1087.
    • (2004) Nat. Med. , vol.10 , pp. 1081-1087
    • Yu, L.1    Huang, Z.2    Mariani, J.3    Wang, Y.4    Moskowitz, M.5    Chen, J.F.6
  • 13
    • 0033766981 scopus 로고    scopus 로고
    • Extracellular metabolism of ATP and other nucleotides
    • Zimmermann, H. 2000. Extracellular metabolism of ATP and other nucleotides. Naunyn. Schmiedebergs Arch. Pharmacol. 362: 299-309.
    • (2000) Naunyn. Schmiedebergs Arch. Pharmacol. , vol.362 , pp. 299-309
    • Zimmermann, H.1
  • 14
    • 0018800321 scopus 로고
    • The mechanism of action of 5-adenosyl-homocysteinase
    • Palmer, J. L., and R. H. Abeles. 1979. The mechanism of action of 5-adenosyl-homocysteinase. J. Biol. Chem. 254: 1217-1226.
    • (1979) J. Biol. Chem. , vol.254 , pp. 1217-1226
    • Palmer, J.L.1    Abeles, R.H.2
  • 15
    • 0033580839 scopus 로고    scopus 로고
    • The mechanism of adenosine formation in cells: Cloning of cytosolic 5′-nucleotidase-1
    • Sala-Newby, G. B., A. C. Skladanowski, and A. C. Newby. 1999. The mechanism of adenosine formation in cells: cloning of cytosolic 5′-nucleotidase-1. J. Biol. Chem. 274: 17789-17793.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17789-17793
    • Sala-Newby, G.B.1    Skladanowski, A.C.2    Newby, A.C.3
  • 16
    • 0027258364 scopus 로고
    • 5′-Adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers
    • Madara, J. L., T. W. Patapoff, B. Gillece-Castro, S. P. Colgan, C. A. Parkos, C. Delp, and R. J. Mrsny. 1993. 5′-Adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers. J. Clin. Invest. 91: 2320-2325.
    • (1993) J. Clin. Invest. , vol.91 , pp. 2320-2325
    • Madara, J.L.1    Patapoff, T.W.2    Gillece-Castro, B.3    Colgan, S.P.4    Parkos, C.A.5    Delp, C.6    Mrsny, R.J.7
  • 17
    • 0027386152 scopus 로고
    • Activated eosinophils evoke chloride secretion in model intestinal epithelia primarily via regulated release of 5′-AMP
    • Resnick, M. B., S. P. Colgan, T. W. Patapoff, R. J. Mrsny, C. S. Awtrey, C. Delp-Archer, P. F. Weller, and J. L. Madara. 1993. Activated eosinophils evoke chloride secretion in model intestinal epithelia primarily via regulated release of 5′-AMP. J. Immunol. 151: 5716-5723.
    • (1993) J. Immunol. , vol.151 , pp. 5716-5723
    • Resnick, M.B.1    Colgan, S.P.2    Patapoff, T.W.3    Mrsny, R.J.4    Awtrey, C.S.5    Delp-Archer, C.6    Weller, P.F.7    Madara, J.L.8
  • 20
    • 0030094734 scopus 로고    scopus 로고
    • Stretch increases inositol 1,4,5-trisphosphate concentration in airway epithelial cells
    • Felix, J. A., M. L. Woodruff, and E. R. Dirksen. 1996. Stretch increases inositol 1,4,5-trisphosphate concentration in airway epithelial cells. Am. J. Respir. Cell Mol. Biol. 14: 296-301.
    • (1996) Am. J. Respir. Cell Mol. Biol. , vol.14 , pp. 296-301
    • Felix, J.A.1    Woodruff, M.L.2    Dirksen, E.R.3
  • 21
    • 0032577474 scopus 로고    scopus 로고
    • Cystic fibrosis transmembrane regulator-independent release of ATP: Its implications for the regulation of P2Y2 receptors in airway epithelia
    • Watt, W. C., E. R. Lazarowski, and R. C. Boucher. 1998. Cystic fibrosis transmembrane regulator-independent release of ATP: its implications for the regulation of P2Y2 receptors in airway epithelia. J. Biol. Chem. 273: 14053-14058.
    • (1998) J. Biol. Chem. , vol.273 , pp. 14053-14058
    • Watt, W.C.1    Lazarowski, E.R.2    Boucher, R.C.3
  • 22
    • 0029954974 scopus 로고    scopus 로고
    • Autocrine signaling through ATP release represents a novel mechanism for cell volume regulation
    • Wang, Y., R. Roman, S. D. Lidofsky, and J. G. Fitz. 1996. Autocrine signaling through ATP release represents a novel mechanism for cell volume regulation. Proc. Natl. Acad. Sci. USA 93: 12020-12025.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 12020-12025
    • Wang, Y.1    Roman, R.2    Lidofsky, S.D.3    Fitz, J.G.4
  • 24
    • 0038128250 scopus 로고    scopus 로고
    • Ecto 5′-nucleotidase and nonspecific alkaline phosphatase: Two AMP-hydrolyzing ectoenzymes with distinct roles in human airways
    • Picher, M., L. H. Burch, A. J. Hirsh, J. Spychala, and R. C. Boucher. 2003. Ecto 5′-nucleotidase and nonspecific alkaline phosphatase: two AMP-hydrolyzing ectoenzymes with distinct roles in human airways. J. Biol. Chem. 278: 13468-13479.
    • (2003) J. Biol. Chem. , vol.278 , pp. 13468-13479
    • Picher, M.1    Burch, L.H.2    Hirsh, A.J.3    Spychala, J.4    Boucher, R.C.5
  • 25
    • 0018827215 scopus 로고
    • Enzymatic characterization of the matrix vesicle alkaline phosphatase isolated from bovine fetal epiphyseal cartilage
    • Fortuna, R., H. C. Anderson, R. P. Carty, and S. W. Sajdera. 1980. Enzymatic characterization of the matrix vesicle alkaline phosphatase isolated from bovine fetal epiphyseal cartilage. Calcif. Tissue Int. 30: 217-225.
    • (1980) Calcif. Tissue Int. , vol.30 , pp. 217-225
    • Fortuna, R.1    Anderson, H.C.2    Carty, R.P.3    Sajdera, S.W.4
  • 26
    • 0019813150 scopus 로고
    • 5′-Nucleotidase from rat heart
    • Naito, Y., and J. M. Lowenstein. 1981. 5′-Nucleotidase from rat heart. Biochemistry 20: 5188-5194.
    • (1981) Biochemistry , vol.20 , pp. 5188-5194
    • Naito, Y.1    Lowenstein, J.M.2
  • 28
    • 0037968292 scopus 로고    scopus 로고
    • Hypoxia enhances Ecto-5′-Nucleotidase activity and cell surface expression in endothelial cells: Role of membrane lipids
    • Ledoux, S., I. Runembert, K. Koumanov, J. B. Michel, G. Trugnan, and G. Friedlander. 2003. Hypoxia enhances Ecto-5′-Nucleotidase activity and cell surface expression in endothelial cells: role of membrane lipids. Circ. Res. 92: 848-855.
    • (2003) Circ. Res. , vol.92 , pp. 848-855
    • Ledoux, S.1    Runembert, I.2    Koumanov, K.3    Michel, J.B.4    Trugnan, G.5    Friedlander, G.6
  • 29
    • 0042386007 scopus 로고    scopus 로고
    • Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: Role of ectonucleotidases and adenosine A2B receptors
    • Eltzschig, H. K., J. C. Ibla, G. T. Furuta, M. O. Leonard, K. A. Jacobson, K. Enjyoji, S. C. Robson, and S. P. Colgan. 2003. Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors. J. Exp. Med. 198: 783-796.
    • (2003) J. Exp. Med. , vol.198 , pp. 783-796
    • Eltzschig, H.K.1    Ibla, J.C.2    Furuta, G.T.3    Leonard, M.O.4    Jacobson, K.A.5    Enjyoji, K.6    Robson, S.C.7    Colgan, S.P.8
  • 35
    • 0042388120 scopus 로고    scopus 로고
    • Adenosine mediates IL-13-induced inflammation and remodeling in the lung: Evidence for an IL- 13-adenosine amplification pathway
    • Blackburn, M. R., G. L. Chun, H. W. J. Young, J. L. Chunn, S. K. Banerjee, and J. A. Elias. 2003. Adenosine mediates IL-13-induced inflammation and remodeling in the lung: evidence for an IL- 13-adenosine amplification pathway. J. Clin. Invest. 112: 332-344.
    • (2003) J. Clin. Invest. , vol.112 , pp. 332-344
    • Blackburn, M.R.1    Chun, G.L.2    Young, H.W.J.3    Chunn, J.L.4    Banerjee, S.K.5    Elias, J.A.6
  • 36
    • 0034679559 scopus 로고    scopus 로고
    • Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction
    • Blackburn, M. R., J. B. Volmer, J. L. Thrasher, H. Zhong, J. R. Crosby, J. J. Lee, and R. E. Kellems. 2000. Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction. J. Exp. Med. 192: 159-170.
    • (2000) J. Exp. Med. , vol.192 , pp. 159-170
    • Blackburn, M.R.1    Volmer, J.B.2    Thrasher, J.L.3    Zhong, H.4    Crosby, J.R.5    Lee, J.J.6    Kellems, R.E.7
  • 37
    • 22544450731 scopus 로고    scopus 로고
    • Adenosine-dependent pulmonary fibrosis in adenosine deaminase-deficient mice
    • Chunn, J. L., J. G. Molina, T. Mi, Y. Xia, R. E. Kellems, and M. R. Blackburn. 2005. Adenosine-dependent pulmonary fibrosis in adenosine deaminase-deficient mice. J. Immunol. 175: 1937-1946.
    • (2005) J. Immunol. , vol.175 , pp. 1937-1946
    • Chunn, J.L.1    Molina, J.G.2    Mi, T.3    Xia, Y.4    Kellems, R.E.5    Blackburn, M.R.6
  • 38
    • 0026585346 scopus 로고
    • Effects of (R)-deoxycoformycin (pentostatin) on intrauterine nucleoside catabolism and embryo viability in the pregnant mouse
    • Knudsen, T. B., R. S. Winters, S. K. Otey, M. R. Blackburn, M. J. Airhart, J. K. Church, and R. G. Skalko. 1992. Effects of (R)-deoxycoformycin (pentostatin) on intrauterine nucleoside catabolism and embryo viability in the pregnant mouse. Teratology 45: 91-103.
    • (1992) Teratology , vol.45 , pp. 91-103
    • Knudsen, T.B.1    Winters, R.S.2    Otey, S.K.3    Blackburn, M.R.4    Airhart, M.J.5    Church, J.K.6    Skalko, R.G.7
  • 40
    • 0023914820 scopus 로고
    • Simple method of estimating severity of pulmonary fibrosis on a numerical scale
    • Ashcroft, T., J. M. Simpson, and V. Timbrell. 1988. Simple method of estimating severity of pulmonary fibrosis on a numerical scale. J. Clin. Pathol. 41: 467-470.
    • (1988) J. Clin. Pathol. , vol.41 , pp. 467-470
    • Ashcroft, T.1    Simpson, J.M.2    Timbrell, V.3
  • 41
    • 3142754919 scopus 로고    scopus 로고
    • A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice
    • Young, H. W., J. G. Molina, D. Dimina, H. Zhong, M. Jacobson, L.-N. L. Chan, T.-S. Chan, J. J. Lee, and M. R. Blackburn. 2004. A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice. J. Immunol 173: 1380-1389.
    • (2004) J. Immunol , vol.173 , pp. 1380-1389
    • Young, H.W.1    Molina, J.G.2    Dimina, D.3    Zhong, H.4    Jacobson, M.5    Chan, L.-N.L.6    Chan, T.-S.7    Lee, J.J.8    Blackburn, M.R.9
  • 42
    • 0029124143 scopus 로고
    • Molecular mechanisms of antifibrotic effect of interferon γ in bleomycin-mouse model of lung fibrosis: Downregulation of TGF-β and procollagen I and III gene expression
    • Gurujeyalakshmi, G., and S. N. Giri. 1995. Molecular mechanisms of antifibrotic effect of interferon γ in bleomycin-mouse model of lung fibrosis: downregulation of TGF-β and procollagen I and III gene expression. Exp. Lung Res. 21: 791-808.
    • (1995) Exp. Lung Res. , vol.21 , pp. 791-808
    • Gurujeyalakshmi, G.1    Giri, S.N.2
  • 43
    • 0035209620 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
    • Fredholm, B. B., A. P. IJzerman, K. A. Jacobson, K. N. Klotz, and J. Linden. 2001. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol. Rev. 53: 527-552.
    • (2001) Pharmacol. Rev. , vol.53 , pp. 527-552
    • Fredholm, B.B.1    Ijzerman, A.P.2    Jacobson, K.A.3    Klotz, K.N.4    Linden, J.5
  • 45
    • 10244222236 scopus 로고    scopus 로고
    • Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: Coordination by extracellular nucleotide metabolism
    • Eltzschig, H. K., L. F. Thompson, J. Karhausen, R. J. Cotta, J. C. Ibla, S. C. Robson, and S. P. Colgan. 2004. Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism. Blood 104: 3986-3992.
    • (2004) Blood , vol.104 , pp. 3986-3992
    • Eltzschig, H.K.1    Thompson, L.F.2    Karhausen, J.3    Cotta, R.J.4    Ibla, J.C.5    Robson, S.C.6    Colgan, S.P.7
  • 47
    • 2442427376 scopus 로고    scopus 로고
    • Metabolism of P2 receptor agonists in human airways: Implications for mucociliary clearance and cystic fibrosis
    • Picher, M., L. H. Burch, and R. C. Boucher. 2004. Metabolism of P2 receptor agonists in human airways: implications for mucociliary clearance and cystic fibrosis. J. Biol. Chem. 279: 20234-20241.
    • (2004) J. Biol. Chem. , vol.279 , pp. 20234-20241
    • Picher, M.1    Burch, L.H.2    Boucher, R.C.3
  • 48
    • 19544391973 scopus 로고    scopus 로고
    • The 'danger' sensors that STOP the immune response: The A2 adenosine receptors?
    • Sitkovsky, M. V., and A. Ohta. 2005. The 'danger' sensors that STOP the immune response: the A2 adenosine receptors? Trends Immunol. 26: 299-304.
    • (2005) Trends Immunol. , vol.26 , pp. 299-304
    • Sitkovsky, M.V.1    Ohta, A.2
  • 49
    • 0032518281 scopus 로고    scopus 로고
    • Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5′-nucleotidase-mediated conversion of adenine nucleotides
    • Morabito, L., M. C. Montesinos, D. M. Schreibman, L. Baiter, L. F. Thompson, R. Resta, G. Carlin, M. A. Huie, and B. N. Cronstein. 1998. Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5′-nucleotidase-mediated conversion of adenine nucleotides. J. Clin. Invest. 101: 295-300.
    • (1998) J. Clin. Invest. , vol.101 , pp. 295-300
    • Morabito, L.1    Montesinos, M.C.2    Schreibman, D.M.3    Baiter, L.4    Thompson, L.F.5    Resta, R.6    Carlin, G.7    Huie, M.A.8    Cronstein, B.N.9
  • 50
    • 0028325787 scopus 로고
    • Adenosine-induced bronchocon-striction and contraction of airway smooth muscle from allergic rabbits with late-phase airway obstruction: Evidence for an inducible adenosine A1 receptor
    • Ali, S., S. J. Mustafa, and W. J. Metzger. 1994. Adenosine-induced bronchocon-striction and contraction of airway smooth muscle from allergic rabbits with late-phase airway obstruction: evidence for an inducible adenosine A1 receptor. J. Pharmacol. Exp. Ther. 268: 1328-1334.
    • (1994) J. Pharmacol. Exp. Ther. , vol.268 , pp. 1328-1334
    • Ali, S.1    Mustafa, S.J.2    Metzger, W.J.3
  • 51
    • 0029915543 scopus 로고    scopus 로고
    • Inhibition of TNF-α expression by adenosine: Role of A3 adenosine receptors
    • Sajjadi, F. G., K. Takabayashi, A. C. Foster, R. C. Domingo, and G. S. Firestein. 1996. Inhibition of TNF-α expression by adenosine: role of A3 adenosine receptors. J. Immunol. 156: 3435-3442.
    • (1996) J. Immunol. , vol.156 , pp. 3435-3442
    • Sajjadi, F.G.1    Takabayashi, K.2    Foster, A.C.3    Domingo, R.C.4    Firestein, G.S.5
  • 54
    • 13444262230 scopus 로고    scopus 로고
    • Adenosine deaminase deficiency: Metabolic basis of immune deficiency and pulmonary inflammation
    • Blackburn, M. R., and R. E. Kellems. 2005. Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation. Adv. Immunol. 86: 1-41.
    • (2005) Adv. Immunol. , vol.86 , pp. 1-41
    • Blackburn, M.R.1    Kellems, R.E.2
  • 55
    • 11144230939 scopus 로고    scopus 로고
    • Synergy between A2B adenosine receptors and hypoxia in activating human lung fibroblasts
    • Zhong, H., L. Belardinelli, T. Maa, and D. Zeng. 2005. Synergy between A2B adenosine receptors and hypoxia in activating human lung fibroblasts. Am. J. Respir. Cell Mol. Biol. 32: 2-8.
    • (2005) Am. J. Respir. Cell Mol. Biol. , vol.32 , pp. 2-8
    • Zhong, H.1    Belardinelli, L.2    Maa, T.3    Zeng, D.4
  • 56
    • 0030588630 scopus 로고    scopus 로고
    • Adenosine receptor agonists differentially regulate IL-10, TNF-α, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice
    • Hasko, G., C. Szabo, Z. H. Nemeth, V. Kvetan, S. M. Pastores, and E. S. Vizi. 1996. Adenosine receptor agonists differentially regulate IL-10, TNF-α, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice. J. Immunol. 157: 4634-4640.
    • (1996) J. Immunol. , vol.157 , pp. 4634-4640
    • Hasko, G.1    Szabo, C.2    Nemeth, Z.H.3    Kvetan, V.4    Pastores, S.M.5    Vizi, E.S.6
  • 57
    • 0033820684 scopus 로고    scopus 로고
    • Adenosine inhibits IL-12 and TNF-α production via adenosine A2a receptor-dependent and independent mechanisms
    • Hasko, G., D. G. Kuhel, J. F. Chen, M. A. Schwarzschild, E. A. Deitch, J. G. Mabley, A. Marton, and C. Szabo. 2000. Adenosine inhibits IL-12 and TNF-α production via adenosine A2a receptor-dependent and independent mechanisms. FASEB J. 14: 2065-2074.
    • (2000) FASEB J. , vol.14 , pp. 2065-2074
    • Hasko, G.1    Kuhel, D.G.2    Chen, J.F.3    Schwarzschild, M.A.4    Deitch, E.A.5    Mabley, J.G.6    Marton, A.7    Szabo, C.8


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