-
1
-
-
0034058486
-
The discovery of the leukotrienes
-
Samuelsson B. The discovery of the leukotrienes. Am J Respir Crit Care Med 2000; 161: 2-6.
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 2-6
-
-
Samuelsson, B.1
-
2
-
-
0027504207
-
5-lipoxygenase and 5- lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes
-
Woods JW, Evans JF, Ethier D, et al. 5-lipoxygenase and 5- lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes. J Exp Med 1993; 178: 1935-46.
-
(1993)
J Exp Med
, vol.178
, pp. 1935-1946
-
-
Woods, J.W.1
Evans, J.F.2
Ethier, D.3
-
4
-
-
33748684386
-
Eicosanoid transcellular biosynthesis: From cell-cell interactions to in vivo tissue responses
-
Folco G, Murphy RC. Eicosanoid transcellular biosynthesis: from cell-cell interactions to in vivo tissue responses. Pharmacol Rev 2006; 58: 375-88.
-
(2006)
Pharmacol Rev
, vol.58
, pp. 375-388
-
-
Folco, G.1
Murphy, R.C.2
-
5
-
-
3242712279
-
Lipoxygenase pathways in atherogenesis
-
Zhao L, Funk CD. Lipoxygenase pathways in atherogenesis. Trends Cardiovasc Med 2004; 14: 191-5.
-
(2004)
Trends Cardiovasc Med
, vol.14
, pp. 191-195
-
-
Zhao, L.1
Funk, C.D.2
-
6
-
-
1442284423
-
Gene suggests asthma drugs may ease cardiovascular inflammation
-
Wickelgren I. Gene suggests asthma drugs may ease cardiovascular inflammation. Science 2004; 303: 941.
-
(2004)
Science
, vol.303
, pp. 941
-
-
Wickelgren, I.1
-
7
-
-
0142124327
-
Leukotriene B4 receptor BLT1 mediates early effector T cell recruitment
-
Tager AM, Bromley SK, Medoff BD, et al. Leukotriene B4 receptor BLT1 mediates early effector T cell recruitment. Nat Immunol 2003; 4: 982-90.
-
(2003)
Nat Immunol
, vol.4
, pp. 982-990
-
-
Tager, A.M.1
Bromley, S.K.2
Medoff, B.D.3
-
8
-
-
34250852792
-
Cysteinyl-leukotrienes and their receptors in asthma and other inflammatory diseases: Critical update and emerging trends
-
Capra V, Thompson MD, Sala A, Cole DE, Folco G, Rovati GE. Cysteinyl-leukotrienes and their receptors in asthma and other inflammatory diseases: critical update and emerging trends. Med Res Rev 2007; 27: 469-527.
-
(2007)
Med Res Rev
, vol.27
, pp. 469-527
-
-
Capra, V.1
Thompson, M.D.2
Sala, A.3
Cole, D.E.4
Folco, G.5
Rovati, G.E.6
-
10
-
-
58149183694
-
IUPHAR-DB: The IUPHAR database of G protein-coupled receptors and ion channels
-
Harmar AJ, Hills RA, Rosser EM, et al. IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels. Nucleic Acids Res 2009; 37: 680-5.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 680-685
-
-
Harmar, A.J.1
Hills, R.A.2
Rosser, E.M.3
-
11
-
-
0030976460
-
A G- protein-coupled receptor for leukotriene B4 that mediates chemotaxis
-
Yokomizo T, Izumi T, Chang K, Takuwa Y, Shimizu T. A G- protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Nature 1997; 387: 620-4.
-
(1997)
Nature
, vol.387
, pp. 620-624
-
-
Yokomizo, T.1
Izumi, T.2
Chang, K.3
Takuwa, Y.4
Shimizu, T.5
-
12
-
-
0034618068
-
A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders
-
Yokomizo T, Kato K, Terawaki K, Izumi T, Shimizu T. A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders. J Exp Med 2000; 192: 421-32.
-
(2000)
J Exp Med
, vol.192
, pp. 421-432
-
-
Yokomizo, T.1
Kato, K.2
Terawaki, K.3
Izumi, T.4
Shimizu, T.5
-
13
-
-
0035853806
-
Hydroxyeicosanoids bind to and activate the low affinity leukotriene B4 receptor, BLT2
-
Yokomizo T, Kato T, Hagiya H, Izumi T, Shimizu Y. Hydroxyeicosanoids bind to and activate the low affinity leukotriene B4 receptor, BLT2. J Biol Chem 2001; 276: 12454-9.
-
(2001)
J Biol Chem
, vol.276
, pp. 12454-12459
-
-
Yokomizo, T.1
Kato, T.2
Hagiya, H.3
Izumi, T.4
Shimizu, Y.5
-
14
-
-
0033600291
-
Characterization of the human cysteinyl leukotriene CysLT1 receptor
-
Lynch KR, Gary GP, O'neill P, et al. Characterization of the human cysteinyl leukotriene CysLT1 receptor. Nature 1999; 399: 789-93.
-
(1999)
Nature
, vol.399
, pp. 789-793
-
-
Lynch, K.R.1
Gary, G.P.2
O'Neill, P.3
-
15
-
-
0023664204
-
Identification and characterization of leukotriene D4 receptors and signal transduction processes in rat basophilic leukemia cells
-
Sarau HM, Mong S, Foley JJ, Wu H-L, Crooke ST. Identification and characterization of leukotriene D4 receptors and signal transduction processes in rat basophilic leukemia cells. J Biol Chem 1987; 262: 4034-41.
-
(1987)
J Biol Chem
, vol.262
, pp. 4034-4041
-
-
Sarau, H.M.1
Mong, S.2
Foley, J.J.3
Wu, H.-L.4
Crooke, S.T.5
-
16
-
-
0034730638
-
Characterization of the human cysteinyl leukotriene 2 receptor
-
Heise CE, O'Dowd BF, Figueroa DJ, et al. Characterization of the human cysteinyl leukotriene 2 receptor. J Biol Chem 2000; 275: 30531-6.
-
(2000)
J Biol Chem
, vol.275
, pp. 30531-30536
-
-
Heise, C.E.1
O'Dowd, B.F.2
Figueroa, D.J.3
-
17
-
-
0034596223
-
The molecular characterization and tissue distribution of the human cysteinyl leukotriene CysLT(2) receptor
-
Takasaki J, Kamohara M, Matsumoto M, et al. The molecular characterization and tissue distribution of the human cysteinyl leukotriene CysLT(2) receptor. Biochem Biophys Res Commun 2000; 274: 316-22.
-
(2000)
Biochem Biophys Res Commun
, vol.274
, pp. 316-322
-
-
Takasaki, J.1
Kamohara, M.2
Matsumoto, M.3
-
18
-
-
0033664314
-
Molecular cloning and characterization of a second human cysteinyl leukotriene receptor: Discovery of a subtype selective agonist
-
Nothacker H-P, Wang Z, Zhu Y, Reinscheid RK, Lin SHS, Civelli O. Molecular cloning and characterization of a second human cysteinyl leukotriene receptor: discovery of a subtype selective agonist. Mol Pharmacol 2000; 58: 1601-8.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 1601-1608
-
-
Nothacker, H.-P.1
Wang, Z.2
Zhu, Y.3
Reinscheid, R.K.4
Lin, S.H.S.5
Civelli, O.6
-
19
-
-
34548746511
-
Leukotriene receptors: Crucial components in vascular inflammation
-
Back M. Leukotriene receptors: crucial components in vascular inflammation. Sci World J 2007; 7: 1422-39.
-
(2007)
Sci World J
, vol.7
, pp. 1422-1439
-
-
Back, M.1
-
20
-
-
0028128943
-
The oxidation hypothesis of atherosclerosis
-
Witztum JL. The oxidation hypothesis of atherosclerosis. Lancet 1994; 344: 793-5.
-
(1994)
Lancet
, vol.344
, pp. 793-795
-
-
Witztum, J.L.1
-
21
-
-
0033552883
-
Atherosclerosis--an inflammatory disease
-
Ross R. Atherosclerosis--an inflammatory disease. N Engl J Med 1999; 340: 115-26.
-
(1999)
N Engl J Med
, vol.340
, pp. 115-126
-
-
Ross, R.1
-
22
-
-
0034648768
-
Atherosclerosis
-
Lusis AJ. Atherosclerosis. Nature 2000; 407: 233-41.
-
(2000)
Nature
, vol.407
, pp. 233-241
-
-
Lusis, A.J.1
-
23
-
-
0034944871
-
Localization of atherosclerosis susceptibility loci to chromosomes 4 and 6 using the Ldlr knockout mouse model
-
Welch CL, Bretschger S, Latib N, et al. Localization of atherosclerosis susceptibility loci to chromosomes 4 and 6 using the Ldlr knockout mouse model. Proc Natl Acad Sci USA 2001; 98: 7946-51.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 7946-7951
-
-
Welch, C.L.1
Bretschger, S.2
Latib, N.3
-
24
-
-
0035920262
-
Genetic locus in mice that blocks development of atherosclerosis despite extreme hyperlipidemia
-
Mehrabian M, Wong J, Wang X, et al. Genetic locus in mice that blocks development of atherosclerosis despite extreme hyperlipidemia. Circ Res 2001; 89: 125-30.
-
(2001)
Circ Res
, vol.89
, pp. 125-130
-
-
Mehrabian, M.1
Wong, J.2
Wang, X.3
-
25
-
-
0037178728
-
Identification of 5- lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice
-
Mehrabian M, Allayee H, Wong J, et al. Identification of 5- lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice. Circ Res 2002; 91: 120-6.
-
(2002)
Circ Res
, vol.91
, pp. 120-126
-
-
Mehrabian, M.1
Allayee, H.2
Wong, J.3
-
26
-
-
0037417973
-
Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis
-
Spanbroek R, Grabner R, Lotzer K, et al. Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis. Proc Natl Acad Sci USA 2003; 100: 1238-43.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1238-1243
-
-
Spanbroek, R.1
Grabner, R.2
Lotzer, K.3
-
27
-
-
0347418277
-
Arachidonate 5- lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis
-
Dwyer JH, Allayee H, Dwyer KM, et al. Arachidonate 5- lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis. N Engl J Med 2004; 350: 29-37.
-
(2004)
N Engl J Med
, vol.350
, pp. 29-37
-
-
Dwyer, J.H.1
Allayee, H.2
Dwyer, K.M.3
-
28
-
-
10744220794
-
The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke
-
Helgadottir A, Manolescu A, Thorleifsson G, Gretarsdottir S, Jonsdottir H, Thorsteinsdottir H. The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nat Genet 2004; 36: 233-9.
-
(2004)
Nat Genet
, vol.36
, pp. 233-239
-
-
Helgadottir, A.1
Manolescu, A.2
Thorleifsson, G.3
Gretarsdottir, S.4
Jonsdottir, H.5
Thorsteinsdottir, H.6
-
29
-
-
13844289142
-
Association between the gene encoding 5-lipoxygenase-activating protein and stroke replicated in a Scottish population
-
Helgadottir A, Gretarsdottir S, St Clair D, et al. Association between the gene encoding 5-lipoxygenase-activating protein and stroke replicated in a Scottish population. Am J Hum Genet 2005; 76: 505-9.
-
(2005)
Am J Hum Genet
, vol.76
, pp. 505-509
-
-
Helgadottir, A.1
Gretarsdottir, S.2
St Clair, D.3
-
30
-
-
29444444748
-
A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction
-
Helgadottir A, Manolescu A, Helgason A, et al. A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. Nat Genet 2006; 38: 68-74.
-
(2006)
Nat Genet
, vol.38
, pp. 68-74
-
-
Helgadottir, A.1
Manolescu, A.2
Helgason, A.3
-
31
-
-
4644301666
-
The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm
-
Zhao L, Moos MP, Grabner R, et al. The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm. Nat Med 2004; 10: 966-73.
-
(2004)
Nat Med
, vol.10
, pp. 966-973
-
-
Zhao, L.1
Moos, M.P.2
Grabner, R.3
-
32
-
-
62649157212
-
Genetic and pharmacological inhibition of the 5-lipoxygenase/leukotriene pathway in atherosclerotic lesion development in ApoE deficient mice
-
Cao RY, St Amand T, Grabner R, Habenicht AJ, Funk CD. Genetic and pharmacological inhibition of the 5-lipoxygenase/leukotriene pathway in atherosclerotic lesion development in ApoE deficient mice. Atherosclerosis 2009; 203: 395-400.
-
(2009)
Atherosclerosis
, vol.203
, pp. 395-400
-
-
Cao, R.Y.1
St Amand, T.2
Grabner, R.3
Habenicht, A.J.4
Funk, C.D.5
-
33
-
-
33745372453
-
Complex inheritance of the 5-lipoxygenase locus influencing atherosclerosis in mice
-
Ghazalpour A, Wang X, Lusis AJ, Mehrabian M. Complex inheritance of the 5-lipoxygenase locus influencing atherosclerosis in mice. Genetics 2006; 173: 943-51.
-
(2006)
Genetics
, vol.173
, pp. 943-951
-
-
Ghazalpour, A.1
Wang, X.2
Lusis, A.J.3
Mehrabian, M.4
-
34
-
-
0346787907
-
From asthma to atherosclerosis--5- lipoxygenase, leukotrienes, and inflammation
-
De Caterina R, Zampolli A. From asthma to atherosclerosis--5- lipoxygenase, leukotrienes, and inflammation. N Engl J Med 2004; 350: 4-7.
-
(2004)
N Engl J Med
, vol.350
, pp. 4-7
-
-
de Caterina, R.1
Zampolli, A.2
-
35
-
-
23944487989
-
The 5-lipoxygenase pathway in arterial wall biology and atherosclerosis
-
Lotzer K, Funk CD, Habenicht AJ. The 5-lipoxygenase pathway in arterial wall biology and atherosclerosis. Biochim Biophys Acta 2005; 1736: 30-7.
-
(2005)
Biochim Biophys Acta
, vol.1736
, pp. 30-37
-
-
Lotzer, K.1
Funk, C.D.2
Habenicht, A.J.3
-
36
-
-
34247548667
-
5-lipoxygenase: Regulation and possible involvement in atherosclerosis
-
Radmark O, Samuelsson B. 5-lipoxygenase: regulation and possible involvement in atherosclerosis. Prostaglandins Other Lipid Mediat 2007; 83: 162-74.
-
(2007)
Prostaglandins Other Lipid Mediat
, vol.83
, pp. 162-174
-
-
Radmark, O.1
Samuelsson, B.2
-
37
-
-
42149105700
-
Cysteinyl-leukotrienes in cerebrovascular disease: Angels and demons?
-
Bäck M. Cysteinyl-leukotrienes in cerebrovascular disease: angels and demons? Arterioscler Thromb Vasc Biol 2008; 28: 805-6.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 805-806
-
-
Bäck, M.1
-
38
-
-
33846545108
-
Association between a leukotriene C4 synthase gene promoter polymorphism and coronary artery calcium in young women: The Muscatine Study
-
Iovannisci DM, Lammer EJ, Steiner L, et al. Association between a leukotriene C4 synthase gene promoter polymorphism and coronary artery calcium in young women: the Muscatine Study. Arterioscler Thromb Vasc Biol 2007; 272: 394-9.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.272
, pp. 394-399
-
-
Iovannisci, D.M.1
Lammer, E.J.2
Steiner, L.3
-
39
-
-
41149089320
-
Genetic variation in members of the leukotriene biosynthesis pathway confer an increased risk of ischemic stroke: A replication study in two independent populations
-
Bevan S, Dichgans M, Wiechmann HE, Gschwendtner A, Meitinger T, Markus HS. Genetic variation in members of the leukotriene biosynthesis pathway confer an increased risk of ischemic stroke: a replication study in two independent populations. Stroke 2008; 39: 1109-14.
-
(2008)
Stroke
, vol.39
, pp. 1109-1114
-
-
Bevan, S.1
Dichgans, M.2
Wiechmann, H.E.3
Gschwendtner, A.4
Meitinger, T.5
Markus, H.S.6
-
40
-
-
0031590522
-
Leukotriene C4 synthase promoter polymorphism and risk of aspirin-induced asthma
-
Sanak M, Simon HU, Szczeklik A. Leukotriene C4 synthase promoter polymorphism and risk of aspirin-induced asthma. Lancet 1997; 350: 1599-1600.
-
(1997)
Lancet
, vol.350
, pp. 1599-1600
-
-
Sanak, M.1
Simon, H.U.2
Szczeklik, A.3
-
41
-
-
42149087142
-
Promotor polymorphisms in leukotriene C4 synthase and risk of ischemic cerebrovascular disease
-
Freiberg JJ, Tybjaerg-Hansen A, Sillesen H, Jensen GB, Nordestgaard BG. Promotor polymorphisms in leukotriene C4 synthase and risk of ischemic cerebrovascular disease. Arterioscler Thromb Vasc Biol 2008; 28: 990-6.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 990-996
-
-
Freiberg, J.J.1
Tybjaerg-Hansen, A.2
Sillesen, H.3
Jensen, G.B.4
Nordestgaard, B.G.5
-
42
-
-
61749085692
-
Leukotriene C4 synthase and ischemic cardiovascular disease and obstructive pulmonary disease in 13,000 individuals
-
Freiberg JJ, Dahl M, Tybjaerg-Hansen A, Grande P, Nordestgaard BG. Leukotriene C4 synthase and ischemic cardiovascular disease and obstructive pulmonary disease in 13,000 individuals. J Mol Cell Cardiol 2009; 46: 579-865.
-
(2009)
J Mol Cell Cardiol
, vol.46
, pp. 579-865
-
-
Freiberg, J.J.1
Dahl, M.2
Tybjaerg-Hansen, A.3
Grande, P.4
Nordestgaard, B.G.5
-
43
-
-
62449296717
-
Genetic variation in the leukotriene pathway and carotid intima-media thickness: A 2- stage replication study
-
Bevan S, Lorenz MW, Sitzer M, Markus HS. Genetic variation in the leukotriene pathway and carotid intima-media thickness: a 2- stage replication study. Stroke 2009; 40: 696-701.
-
(2009)
Stroke
, vol.40
, pp. 696-701
-
-
Bevan, S.1
Lorenz, M.W.2
Sitzer, M.3
Markus, H.S.4
-
44
-
-
33744497551
-
Expression of 5- lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability
-
Qiu H, Gabrielsen A, Agardh HE, et al. Expression of 5- lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability. Proc Natl Acad Sci USA 2006; 103: 8161-6.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 8161-8166
-
-
Qiu, H.1
Gabrielsen, A.2
Agardh, H.E.3
-
45
-
-
61349157875
-
The putative role of leukotrienes in experimental atherogenesis
-
Jawien J. The putative role of leukotrienes in experimental atherogenesis. Pol Arch Med Wewn 2009; 119: 909-3.
-
(2009)
Pol Arch Med Wewn
, vol.119
, pp. 909-903
-
-
Jawien, J.1
-
46
-
-
0038448178
-
5-lipoxygenase-derived leukotrienes. Mediators also of atherosclerotic inflammation
-
Radmark O. 5-lipoxygenase-derived leukotrienes. Mediators also of atherosclerotic inflammation. Arterioscler Thromb Vasc Biol 2003; 23: 1140-2.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 1140-1142
-
-
Radmark, O.1
-
47
-
-
0024211197
-
Leukotriene B4 production in human atherosclerotic plaques
-
De Caterina R, Mazzone A, Giannessi D, et al. Leukotriene B4 production in human atherosclerotic plaques. Biomed Biochim Acta 1988; 47: 182-5.
-
(1988)
Biomed Biochim Acta
, vol.47
, pp. 182-185
-
-
de Caterina, R.1
Mazzone, A.2
Giannessi, D.3
-
48
-
-
52749086712
-
Leukotriene B4: Early mediator of atherosclerosis in obstructive sleep apnoea?
-
Lefebvre B, Pepin JL, Baguet JP, et al. Leukotriene B4: early mediator of atherosclerosis in obstructive sleep apnoea? Eur Respir J 2008; 32: 113-20.
-
(2008)
Eur Respir J
, vol.32
, pp. 113-120
-
-
Lefebvre, B.1
Pepin, J.L.2
Baguet, J.P.3
-
49
-
-
33644749435
-
Inhibition of five lipoxygenase activating protein (FLAP) by MK-886 decreases atherosclerosis in apoE/LDLR-double knockout mice
-
Jawien J, Gajda M, Rudling M, et al. Inhibition of five lipoxygenase activating protein (FLAP) by MK-886 decreases atherosclerosis in apoE/LDLR-double knockout mice. Eur J Clin Invest 2006; 36: 141-6.
-
(2006)
Eur J Clin Invest
, vol.36
, pp. 141-146
-
-
Jawien, J.1
Gajda, M.2
Rudling, M.3
-
50
-
-
0036124634
-
Leukotriene B4 receptor antagonism reduces monocytic foam cells in mice
-
Aiello RJ, Bourassa PA, Lindsey S, Weng W, Freeman A, Showell HJ. Leukotriene B4 receptor antagonism reduces monocytic foam cells in mice. Arterioscler Thromb Vasc Biol 2002; 22: 443-9.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 443-449
-
-
Aiello, R.J.1
Bourassa, P.A.2
Lindsey, S.3
Weng, W.4
Freeman, A.5
Showell, H.J.6
-
51
-
-
1042268024
-
Role of leukotriene B4 receptors in the development of atherosclerosis: Potential mechanisms
-
Subbarao K, Jala VR, Mathis S, et al. Role of leukotriene B4 receptors in the development of atherosclerosis: potential mechanisms. Arterioscler Thromb Vasc Biol 2004; 24: 369-75.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 369-375
-
-
Subbarao, K.1
Jala, V.R.2
Mathis, S.3
-
52
-
-
23044443692
-
Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment
-
Heller EA, Liu E, Tager AM, et al. Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment. Circulation 2005; 112: 578-86.
-
(2005)
Circulation
, vol.112
, pp. 578-586
-
-
Heller, E.A.1
Liu, E.2
Tager, A.M.3
-
53
-
-
28444431957
-
Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia
-
Back M, Bu DX, Branstrom R, Sheikine Y, Yan ZQ, Hansson GK. Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. Proc Natl Acad Sci USA 2005; 102: 17501-6.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17501-17506
-
-
Back, M.1
Bu, D.X.2
Branstrom, R.3
Sheikine, Y.4
Yan, Z.Q.5
Hansson, G.K.6
-
54
-
-
63449134292
-
Leukotriene receptor antagonism and the prevention of extracellular matrix degradation during atherosclerosis and in-stent stenosis
-
Hlawaty H, Jacob MP, Louedec L, et al. Leukotriene receptor antagonism and the prevention of extracellular matrix degradation during atherosclerosis and in-stent stenosis. Arterioscler Thromb Vasc Biol 2009; 29: 518-24.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 518-524
-
-
Hlawaty, H.1
Jacob, M.P.2
Louedec, L.3
-
55
-
-
34548791897
-
Regulation of immune cells by eicosanoid receptors
-
Kimand N, Luster AD. Regulation of immune cells by eicosanoid receptors. Sci World J 2007; 7: 1307-28.
-
(2007)
Sci World J
, vol.7
, pp. 1307-1328
-
-
Kimand, N.1
Luster, A.D.2
-
56
-
-
34247123754
-
5-Lipoxygenase- activating protein: A potential link between innate and adaptive immunity in atherosclerosis and adipose tissue inflammation
-
Back M, Sultan A, Ovchinnikova O, Hansson GK. 5-Lipoxygenase- activating protein: a potential link between innate and adaptive immunity in atherosclerosis and adipose tissue inflammation. Circ Res 100: 946-9 (2007).
-
(2007)
Circ Res
, vol.100
, pp. 946-949
-
-
Back, M.1
Sultan, A.2
Ovchinnikova, O.3
Hansson, G.K.4
-
57
-
-
70349303279
-
Differential inflammatory activity across human abdominal aortic aneurysms reveals neutrophil-derived leukotriene B4 as a major chemotactic factor released from the intraluminal thrombus
-
Houard X, Ollivier V, Louedec L, Michel JB, Back M. Differential inflammatory activity across human abdominal aortic aneurysms reveals neutrophil-derived leukotriene B4 as a major chemotactic factor released from the intraluminal thrombus. FASEB J 2009; 23: 1376-83.
-
(2009)
FASEB J
, vol.23
, pp. 1376-1383
-
-
Houard, X.1
Ollivier, V.2
Louedec, L.3
Michel, J.B.4
Back, M.5
-
58
-
-
34447538179
-
Angiotensin II- induced abdominal aortic aneurysm occurs independently of the 5- lipoxygenase pathway in apolipoprotein E-deficient mice
-
Cao RY, Adams MA, Habenicht AJ, Funk CD. Angiotensin II- induced abdominal aortic aneurysm occurs independently of the 5- lipoxygenase pathway in apolipoprotein E-deficient mice. Prostaglandins Other Lipid Mediat 2007; 84: 34-42.
-
(2007)
Prostaglandins Other Lipid Mediat
, vol.84
, pp. 34-42
-
-
Cao, R.Y.1
Adams, M.A.2
Habenicht, A.J.3
Funk, C.D.4
-
59
-
-
18544395256
-
Leukotriene B4 is an indirectly acting vasoconstrictor in guinea pig aorta via an inducible type of BLT receptor
-
Back M, Qiu H, Haeggstrom JZ, Sakata K. Leukotriene B4 is an indirectly acting vasoconstrictor in guinea pig aorta via an inducible type of BLT receptor. Am J Physiol Heart Circ Physiol 2004; 287: 419-24.
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.287
, pp. 419-424
-
-
Back, M.1
Qiu, H.2
Haeggstrom, J.Z.3
Sakata, K.4
-
60
-
-
1542319910
-
The contractile action of leukotriene B4 in the guinea-pig lung involves a vascular component
-
Sakata K, Dahlen SE, Back M. The contractile action of leukotriene B4 in the guinea-pig lung involves a vascular component. Br J Pharmacol 2004; 141: 449-56.
-
(2004)
Br J Pharmacol
, vol.141
, pp. 449-456
-
-
Sakata, K.1
Dahlen, S.E.2
Back, M.3
-
61
-
-
33751113286
-
Leukotriene receptors in atherosclerosis
-
Back M, Hansson GK. Leukotriene receptors in atherosclerosis. Ann Med 2006; 38: 493-502.
-
(2006)
Ann Med
, vol.38
, pp. 493-502
-
-
Back, M.1
Hansson, G.K.2
-
62
-
-
0037495055
-
Amino acid differences in the deduced 5-lipoxygenase sequence of CAST atherosclerosis- resistance mice confer impaired activity when introduced into the human ortholog
-
Kuhn H, Anton M, Gerth C, et al. Amino acid differences in the deduced 5-lipoxygenase sequence of CAST atherosclerosis- resistance mice confer impaired activity when introduced into the human ortholog. Arterioscler Thromb Vasc Biol 2003; 23: 1072-6.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 1072-1076
-
-
Kuhn, H.1
Anton, M.2
Gerth, C.3
-
63
-
-
42749088701
-
The oral cavity and age: A site of chronic inflammation?
-
Back M, Hlawaty H, Labat C, Michel JB, Brink C. The oral cavity and age: a site of chronic inflammation? PLoS One 2007; 2: e1351.
-
(2007)
PLoS One
, vol.e1351
, pp. 2
-
-
Back, M.1
Hlawaty, H.2
Labat, C.3
Michel, J.B.4
Brink, C.5
-
64
-
-
34250835541
-
Inhibited aortic aneurysm formation in BLT1-deficient mice
-
Ahluwalia N, Lin AY, Tager AM, et al. Inhibited aortic aneurysm formation in BLT1-deficient mice. J Immunol 2007; 179: 691-7.
-
(2007)
J Immunol
, vol.179
, pp. 691-697
-
-
Ahluwalia, N.1
Lin, A.Y.2
Tager, A.M.3
-
65
-
-
0023352955
-
Leukotriene biosynthesis by canine and human coronary arteries
-
Piomelli D, Feinmark SJ, Cannon PJ. Leukotriene biosynthesis by canine and human coronary arteries. J Pharmacol Exp Ther 1987; 241: 763-70.
-
(1987)
J Pharmacol Exp Ther
, vol.241
, pp. 763-770
-
-
Piomelli, D.1
Feinmark, S.J.2
Cannon, P.J.3
-
66
-
-
0026504185
-
Increased urinary leukotriene excretion in patients with cardiac ischemia. In vivo evidence for 5-lipoxygenase activation
-
Carry M, Korley V, Willerson JT, Weigelt L, Ford-Hutchinson AW, Tagari P. Increased urinary leukotriene excretion in patients with cardiac ischemia. In vivo evidence for 5-lipoxygenase activation. Circulation 1992; 85: 230-6.
-
(1992)
Circulation
, vol.85
, pp. 230-236
-
-
Carry, M.1
Korley, V.2
Willerson, J.T.3
Weigelt, L.4
Ford-Hutchinson, A.W.5
Tagari, P.6
-
67
-
-
0027373673
-
Enhanced excretion of urinary leukotriene E4 in coronary artery disease and after coronary artery bypass surgery
-
Allen S, Sampson AP, Piper PJ, Chester AH, Ohri SK, Yacoub MH. Enhanced excretion of urinary leukotriene E4 in coronary artery disease and after coronary artery bypass surgery. Coron Artery Dis 1993; 4: 899-904.
-
(1993)
Coron Artery Dis
, vol.4
, pp. 899-904
-
-
Allen, S.1
Sampson, A.P.2
Piper, P.J.3
Chester, A.H.4
Ohri, S.K.5
Yacoub, M.H.6
-
68
-
-
0032560647
-
Differential leukotriene constrictor responses in human atherosclerotic coronary arteries
-
Allen S, Dashwood M, Morrison K, Yacoub M. Differential leukotriene constrictor responses in human atherosclerotic coronary arteries. Circulation 1998; 97: 2406-13.
-
(1998)
Circulation
, vol.97
, pp. 2406-2413
-
-
Allen, S.1
Dashwood, M.2
Morrison, K.3
Yacoub, M.4
-
69
-
-
34447310550
-
Increased leukotriene concentrations in gingival crevicular fluid from subjects with periodontal disease and atherosclerosis
-
Back M, Airila-Mansson S, Jogestrand T, Soder B, Soder PO. Increased leukotriene concentrations in gingival crevicular fluid from subjects with periodontal disease and atherosclerosis. Atherosclerosis 2007; 193: 389-94.
-
(2007)
Atherosclerosis
, vol.193
, pp. 389-394
-
-
Back, M.1
Airila-Mansson, S.2
Jogestrand, T.3
Soder, B.4
Soder, P.O.5
-
70
-
-
30544447195
-
CysLT1 receptor is a target for extracellular nucleotide-induced heterologous desensiti- zation: A possible feedback mechanism in inflammation
-
Capra V, Ravasi S, Accomazzo MR, et al. CysLT1 receptor is a target for extracellular nucleotide-induced heterologous desensiti- zation: a possible feedback mechanism in inflammation. J Cell Sci 2005; 118: 5625-36.
-
(2005)
J Cell Sci
, vol.118
, pp. 5625-5636
-
-
Capra, V.1
Ravasi, S.2
Accomazzo, M.R.3
-
71
-
-
34548783949
-
Cysteinyl-leukotriene receptors and cellular signals
-
Rovati GE, Capra V. Cysteinyl-leukotriene receptors and cellular signals. Sci World J 2007; 7: 1375-92.
-
(2007)
Sci World J
, vol.7
, pp. 1375-1392
-
-
Rovati, G.E.1
Capra, V.2
-
72
-
-
0034933024
-
Cysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by human mast cells
-
Mellor EA, Maekawa A, Austen KF, Boyce JA. Cysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by human mast cells. Proc Nat Acad USA 2001; 98: 7964-9.
-
(2001)
Proc Nat Acad USA
, vol.98
, pp. 7964-7969
-
-
Mellor, E.A.1
Maekawa, A.2
Austen, K.F.3
Boyce, J.A.4
-
73
-
-
25844519676
-
Identification of endogenous surrogate ligands for human P2Y12 receptors by in silico and in vitro methods
-
Nonaka Y, Hiramoto H, Fujita N. Identification of endogenous surrogate ligands for human P2Y12 receptors by in silico and in vitro methods. Biochem Biophys Res Commun 2005; 337: 281-8.
-
(2005)
Biochem Biophys Res Commun
, vol.337
, pp. 281-288
-
-
Nonaka, Y.1
Hiramoto, H.2
Fujita, N.3
-
74
-
-
33749323854
-
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl- leukotrienes receptor
-
Ciana P, Fumagalli M, Trincavelli ML, et al. The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl- leukotrienes receptor. EMBO J 2006; 25: 4615-27.
-
(2006)
EMBO J
, vol.25
, pp. 4615-4627
-
-
Ciana, P.1
Fumagalli, M.2
Trincavelli, M.L.3
-
75
-
-
60549106097
-
P2Y6 receptors require an intact cysteinyl leukotriene synthetic and signaling system to induce survival and activation of mast cells
-
Jiang Y, Borrelli L, Bacskai BJ, Kanaoka Y, Boyce JA. P2Y6 receptors require an intact cysteinyl leukotriene synthetic and signaling system to induce survival and activation of mast cells. J Immunol 2009; 182: 1129-37.
-
(2009)
J Immunol
, vol.182
, pp. 1129-1137
-
-
Jiang, Y.1
Borrelli, L.2
Bacskai, B.J.3
Kanaoka, Y.4
Boyce, J.A.5
-
76
-
-
28244496554
-
CysLT(1) leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors
-
Mamedova L, Capra V, Accomazzo MR, et al. CysLT(1) leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors. Biochem Pharmacol 2005; 71: 115-25.
-
(2005)
Biochem Pharmacol
, vol.71
, pp. 115-125
-
-
Mamedova, L.1
Capra, V.2
Accomazzo, M.R.3
-
77
-
-
44649168284
-
Multidrug resistance protein-1 affects oxidative stress, endothelial dysfunction, and atherogenesis via leukotriene C4 export
-
Mueller CF, Wassmann K, Widder JD, et al. Multidrug resistance protein-1 affects oxidative stress, endothelial dysfunction, and atherogenesis via leukotriene C4 export. Circulation 2008; 117: 2912-8.
-
(2008)
Circulation
, vol.117
, pp. 2912-2918
-
-
Mueller, C.F.1
Wassmann, K.2
Widder, J.D.3
-
78
-
-
0346192293
-
Dominant expression of the CysLT2 receptor accounts for calcium signaling by cysteinyl leukotrienes in human umbilical vein endothelial cells
-
Sjostrom M, Johansson AS, Schroder O, Qiu H, Palmblad J, Haeggstrom JZ. Dominant expression of the CysLT2 receptor accounts for calcium signaling by cysteinyl leukotrienes in human umbilical vein endothelial cells. Arterioscler Thromb Vasc Biol 2003; 23: 37-41.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 37-41
-
-
Sjostrom, M.1
Johansson, A.S.2
Schroder, O.3
Qiu, H.4
Palmblad, J.5
Haeggstrom, J.Z.6
-
79
-
-
0346822886
-
Differential leukotriene receptor expression and calcium responses in endothelial cells and macrophages indicate5-lipoxygenase-dependent circuits of inflammation and atherogenesis
-
Lotzer K, Spanbroek R, Hildner M, et al. Differential leukotriene receptor expression and calcium responses in endothelial cells and macrophages indicate5-lipoxygenase-dependent circuits of inflammation and atherogenesis. Arter Thromb Vasc Biol 2003; 23: 32-6.
-
(2003)
Arter Thromb Vasc Biol
, vol.23
, pp. 32-36
-
-
Lotzer, K.1
Spanbroek, R.2
Hildner, M.3
-
80
-
-
9344227345
-
Directed vascular expression of human cysteinyl leukotriene 2 receptor modulates endothelial permeability and systemic blood pressure
-
Hui Y, Cheng Y, Smalera I, et al. Directed vascular expression of human cysteinyl leukotriene 2 receptor modulates endothelial permeability and systemic blood pressure. Circulation 2004; 110: 3360-6.
-
(2004)
Circulation
, vol.110
, pp. 3360-3366
-
-
Hui, Y.1
Cheng, Y.2
Smalera, I.3
-
81
-
-
0030912136
-
Cysteinyl leukotrienes induce P-selectin expression in human endothelial cells via a non- CysLT1 receptor-mediated mechanism
-
Pedersen KE, Bochner BS, Undem BJ. Cysteinyl leukotrienes induce P-selectin expression in human endothelial cells via a non- CysLT1 receptor-mediated mechanism. J Pharmacol Exp Therap 1997; 281: 655-62.
-
(1997)
J Pharmacol Exp Therap
, vol.281
, pp. 655-662
-
-
Pedersen, K.E.1
Bochner, B.S.2
Undem, B.J.3
-
82
-
-
33646594755
-
Cysteinyl leukotriene 2 receptor and protease-activated receptor 1 activate strongly correlated early genes in human endothelial cells
-
Uzonyi B, Lotzer K, Jahn S, et al. Cysteinyl leukotriene 2 receptor and protease-activated receptor 1 activate strongly correlated early genes in human endothelial cells. Proc Natl Acad Sci USA 2006; 103: 6326-31.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6326-6331
-
-
Uzonyi, B.1
Lotzer, K.2
Jahn, S.3
-
83
-
-
34548746511
-
Leukotriene receptors: Crucial components in vascular inflammation
-
Bäck M. Leukotriene receptors: crucial components in vascular inflammation. Sci World J 2007; 7: 1422-39.
-
(2007)
Sci World J
, vol.7
, pp. 1422-1439
-
-
Bäck, M.1
-
84
-
-
33750579451
-
Cysteinyl- leukotriene receptor antagonists: Present situation and future opportunities
-
Capra V, Ambrosio M, Riccioni G, Rovati GE. Cysteinyl- leukotriene receptor antagonists: present situation and future opportunities. Curr Med Chem 2006; 13: 3213-26.
-
(2006)
Curr Med Chem
, vol.13
, pp. 3213-3226
-
-
Capra, V.1
Ambrosio, M.2
Riccioni, G.3
Rovati, G.E.4
-
85
-
-
58749083360
-
Leukotriene signaling in atherosclerosis and ischemia
-
Back M. Leukotriene signaling in atherosclerosis and ischemia. Cardiovasc Drugs Ther 2009; 23: 41-8.
-
(2009)
Cardiovasc Drugs Ther
, vol.23
, pp. 41-48
-
-
Back, M.1
-
86
-
-
35448968676
-
The effect of montelukast and low-dose theophylline on cardiovascular disease risk factors in asthmatics
-
Allayee H, Hartiala J, Lee W, et al. The effect of montelukast and low-dose theophylline on cardiovascular disease risk factors in asthmatics. Chest 2007; 132: 868-74.
-
(2007)
Chest
, vol.132
, pp. 868-874
-
-
Allayee, H.1
Hartiala, J.2
Lee, W.3
-
87
-
-
34548450776
-
Role of cysteinyl leukotrienes in the proliferation and the migration of murine vascular smooth muscle cells in vivo and in vitro
-
Kaetsu Y, Yamamoto Y, Sugihara S, et al. Role of cysteinyl leukotrienes in the proliferation and the migration of murine vascular smooth muscle cells in vivo and in vitro. Cardiovasc Res 2007; 76: 160-6.
-
(2007)
Cardiovasc Res
, vol.76
, pp. 160-166
-
-
Kaetsu, Y.1
Yamamoto, Y.2
Sugihara, S.3
-
88
-
-
67349098843
-
Anti-atherogenic effects of montelukast associated with reduced MCP-1 expression in a rabbit carotid balloon injury model
-
Ge S, Zhou G, Cheng S, et al. Anti-atherogenic effects of montelukast associated with reduced MCP-1 expression in a rabbit carotid balloon injury model. Atherosclerosis 2009; 205: 74-9.
-
(2009)
Atherosclerosis
, vol.205
, pp. 74-79
-
-
Ge, S.1
Zhou, G.2
Cheng, S.3
-
89
-
-
0023271776
-
Myocardial salvage induced by REV-5901: An inhibitor and antagonist of the leukotrienes
-
Mullane K, Hatala MA, Kraemer R, Sessa W, Westlin W. Myocardial salvage induced by REV-5901: an inhibitor and antagonist of the leukotrienes. J Cardiovasc Pharmacol 1987; 10: 398-406.
-
(1987)
J Cardiovasc Pharmacol
, vol.10
, pp. 398-406
-
-
Mullane, K.1
Hatala, M.A.2
Kraemer, R.3
Sessa, W.4
Westlin, W.5
-
90
-
-
0026085584
-
Characterization of LY233569 on 5-lipoxygenase and reperfusion injury of ischemic myocardium
-
Hahn RA, MacDonald BR, Simpson PJ, et al. Characterization of LY233569 on 5-lipoxygenase and reperfusion injury of ischemic myocardium. J Pharmacol Exp Ther 1991; 256: 94-102.
-
(1991)
J Pharmacol Exp Ther
, vol.256
, pp. 94-102
-
-
Hahn, R.A.1
Macdonald, B.R.2
Simpson, P.J.3
-
91
-
-
85047678558
-
Peptide leukotriene receptor antagonism in myocardial ischaemia and reperfusion
-
Hock CE, Beck LD, Papa LA. Peptide leukotriene receptor antagonism in myocardial ischaemia and reperfusion. Cardiovasc Res 1992; 26: 1206-11.
-
(1992)
Cardiovasc Res
, vol.26
, pp. 1206-1211
-
-
Hock, C.E.1
Beck, L.D.2
Papa, L.A.3
-
92
-
-
0026665573
-
Evaluation of LY203647 on cardiovascular leukotriene D4 receptors and myocardial reperfusion injury
-
Hahn RA, MacDonald BR, Morgan E, et al. Evaluation of LY203647 on cardiovascular leukotriene D4 receptors and myocardial reperfusion injury. J Pharmacol Exp Ther 1992; 260: 979-89.
-
(1992)
J Pharmacol Exp Ther
, vol.260
, pp. 979-989
-
-
Hahn, R.A.1
Macdonald, B.R.2
Morgan, E.3
-
93
-
-
0025194891
-
Thromboxane A2 and peptidoleukotrienes contribute to the myocardial ischemia and contractile dysfunction in response to intracoronary infusion of complement C5a in pigs
-
Ito BR, Roth DM, Engler RL. Thromboxane A2 and peptidoleukotrienes contribute to the myocardial ischemia and contractile dysfunction in response to intracoronary infusion of complement C5a in pigs. Circ Res 1990; 66: 596-607.
-
(1990)
Circ Res
, vol.66
, pp. 596-607
-
-
Ito, B.R.1
Roth, D.M.2
Engler, R.L.3
-
94
-
-
0024840668
-
Protective effects of a thromboxane synthetase inhibitor, a thromboxane antagonist, a lipoxygenase inhibitor and a leukotriene C4, D4 antagonist on myocardial injury caused by acute myocardial infarction in the canine heart
-
Ito T, Toki Y, Hieda N, et al. Protective effects of a thromboxane synthetase inhibitor, a thromboxane antagonist, a lipoxygenase inhibitor and a leukotriene C4, D4 antagonist on myocardial injury caused by acute myocardial infarction in the canine heart. Jpn Circ J 1989; 53: 1115-21.
-
(1989)
Jpn Circ J
, vol.53
, pp. 1115-1121
-
-
Ito, T.1
Toki, Y.2
Hieda, N.3
-
95
-
-
23844530173
-
Leukotriene modifiers as potential therapeutics for cardiovascular disease
-
Funk CD. Leukotriene modifiers as potential therapeutics for cardiovascular disease. Nature 2005; 4: 664-72.
-
(2005)
Nature
, vol.4
, pp. 664-672
-
-
Funk, C.D.1
-
96
-
-
57149118054
-
Leukotriene modifiers in the treatment of cardiovascular diseases
-
Riccioni G, Capra V, D'Orazio N, Bucciarelli T, Bazzano LA. Leukotriene modifiers in the treatment of cardiovascular diseases. J Leukoc Biol 2008; 84: 1374-8.
-
(2008)
J Leukoc Biol
, vol.84
, pp. 1374-1378
-
-
Riccioni, G.1
Capra, V.2
D'Orazio, N.3
Bucciarelli, T.4
Bazzano, L.A.5
|