Genetic locus in mice that blocks development of atherosclerosis despite extreme hyperlipidemia

Circulation Research

Volumn 89, Issue 2, 2001, Pages 125-130

  Mehrabian, Margarete ^a   Wong, Jack ^a   Wang, Xuping ^a   Jiang, Zhiming ^a   Shi, Weibin ^a   Fogelman, Alan M ^a   Lusis, Aldons J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Bone marrow transplantation; Congenic strains; Insulin; Peroxisome proliferator activated receptor ; Quantitative trait locus

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA DISEASE; ARTICLE; ATHEROSCLEROSIS; BLOOD PRESSURE; BODY FAT; CHROMOSOME 6; CONGENIC STRAIN; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE IDENTIFICATION; GENE LOCUS; GENE MUTATION; GENETIC CROSS; HYPERLIPIDEMIA; LIPOPROTEIN BLOOD LEVEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE;

EID: 0035920262     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/hh1401.093458     Document Type: Article

References (21)

1. Atherosclerosis
2. Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice
3. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
4. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
5. Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice
6. Genetic background determines the extent of atherosclerosis in apoE-deficient mice
7. Determinants of atherosclerosis susceptibility in C3H and C57BL/6 mouse model: Evidence for involvement of endothelial cells but not blood cells or cholesterol metabolism
8. MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations
9. Influence of mouse apolipoprotein A-II on plasma lipoproteins in transgenic mice
10. Differential responses of endothelial cells to oxidized lipoproteins contribute to genetic differences in atherosclerosis in mice
11. Effect of macrophage-derived apolipoprotein E on established atherosclerosis in apolipoprotein E-deficient mice
12. Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model
13. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
14. Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis
15. Apolipoprotein B mRNA editing: Direct determination of the edited base and occurrence in non-apolipoprotein B-producing cell lines
16. Peroxisome proliferator-activated receptor γ ligands and atherosclerosis: Ending the heartaches
17. PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
18. Progress in cardiovascular biology: PPAR for the course
19. Peroxisome proliferator-activated receptor γ ligands inhibit development of atherosclerosis in LDL receptor-deficient mice
20. Genetic control of high density lipoprotein (HDL) levels and composition in an interspecific mouse cross (CAST/Ei×C57BL/6J)
21. The murine type 1 diabetes loci, Idd1, Idd3, Idd5, Idd9, and Idd17/lO/18, do not control thymic CD4-CD8-/TCRalphabeta+ deficiency in the nonobese diabetic mouse