Leukotriene B4 signaling through NF-κB-dependent BLT 1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 48, 2005, Pages 17501-17506

  Bäck, Magnus ^a   Bu, De Xiu ^a   Bränström, Robert ^a   Sheikine, Yuri ^a   Yan, Zhong Qun ^a   Hansson, Göran K ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cell proliferation; Chemotaxis; Eicosanoids; Lipoxygenase; Restenosis

Indexed keywords

2 (2,6 DIHYDROXYHEXYL) 6 (3 HYDROXY 1,5 UNDECADIENYL)PYRIDINE; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; BLT 1 RECEPTOR; CELL SURFACE RECEPTOR; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LEUKOTRIENE B4; MESSENGER RNA; UNCLASSIFIED DRUG; AMELUBANT; AMIDINE; CARBAMIC ACID DERIVATIVE; FATTY ALCOHOL; GLYCOL; LEUKOTRIENE B4 RECEPTOR; LTB4R PROTEIN, HUMAN; LTB4R PROTEIN, RAT; PURINE P2 RECEPTOR;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARACHIDONIC ACID METABOLISM; ARTERY INTIMA PROLIFERATION; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLOOD VESSEL INJURY; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MACROPHAGE; MALE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; VASCULAR SMOOTH MUSCLE; ANALYSIS OF VARIANCE; ANIMAL; CAROTID ARTERY INJURY; CELL MOTION; COMPARATIVE STUDY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; ELECTROPHYSIOLOGY; HYPERPLASIA; INTIMA; METABOLISM; PHYSIOLOGY; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; UPREGULATION; WESTERN BLOTTING;

ADENOVIRIDAE; ANIMALIA;

AMIDINES; ANALYSIS OF VARIANCE; ANIMALS; ATHEROSCLEROSIS; BLOTTING, WESTERN; CARBAMATES; CAROTID ARTERY INJURIES; CELL MOVEMENT; ELECTROPHYSIOLOGY; FATTY ALCOHOLS; GLYCOLS; HUMANS; HYPERPLASIA; LEUKOTRIENE B4; MALE; MUSCLE, SMOOTH, VASCULAR; NF-KAPPA B; PATCH-CLAMP TECHNIQUES; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, LEUKOTRIENE B4; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION; TUNICA INTIMA; UP-REGULATION;

EID: 28444431957     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0505845102     Document Type: Article

References (41)

1. Funk, C. D. (2001) Science 294, 1871-1875.
2. Bäck, M. (2002) Life Sci. 71, 611-622.
3. Brink, C., Dahlen, S. E., Drazen, J., Evans, J. F., Hay, D. W., Nicosia, S., Serhan, C. N., Shimizu, T. & Yokomizo, T. (2003) Pharmacol. Rev. 55, 195-227.
4. Yokomizo, T., Izumi, T., Chang, K., Takuwa, Y. & Shimizu, T. (1997) Nature 387, 620-624.
5. Yokomizo, T., Kato, K., Terawaki, K., Izumi, T. & Shimizu, T. (2000) J. Exp. Med. 192, 421-431.
6. Dahlén, S. E., Björk, J., Hedqvist, P., Arfors, K. E., Hammarström, S., Lindgren, J. A. & Samuelsson, B. (1981) Proc. Natl. Acad. Sci. USA 78, 3887-3891.
7. Heller, E. A., Liu, E., Tager, A. M., Sinha, S., Roberts, J. D., Koehn, S. L., Libby, P., Aikawa, E. R., Chen, J. Q., Huang, P., et al. (2005) Circulation 112, 578-586.
8. Goodarzi, K., Goodarzi, M., Tager, A. M., Luster, A. D. & von Andrian, U. H. (2003) Nat. Immunol. 4, 965-973.
9. Huang, W. W., Garcia-Zepeda, E. A., Sauty, A., Oettgen, H. C., Rothenberg, M. E. & Luster, A. D. (1998) J. Exp. Med. 188, 1063-1074.
10. Ott, V. L., Cambier, J. C., Kappler, J., Marrack, P. & Swanson, B. J. (2003) Nat. Immunol. 4, 974-981.
11. Tager, A. M., Bromley, S. K., Medoff, B. D., Islam, S. A., Bercury, S. D., Friedrich, E. B., Carafone, A. D., Gerszten, R. E. & Luster, A. D. (2003) Nat. Immunol. 4, 982-990.
12. Mehrabian, M., Allayee, H., Wong, J., Shi, W., Wang, X. P., Shaposhnik, Z., Funk, C. D. & Lusis, A. J. (2002) Circ. Res. 91, 120-126.
13. Spanbroek, R., Gräbner, R., Lötzer, K., Hildner, M., Urbach, A., Rühling, K., Moos, M. P., Kaiser, B., Cohnert, T. U., Wahlers, T., et al. (2003) Proc. Natl. Acad. Sci. USA 100, 1238-1243.
14. Dwyer, J. H., Allayee, H., Dwyer, K. M., Fan, J., Wu, H., Mar, R., Lusis, A. J. & Mehrabian, M. (2004) N. Engl. J. Med. 350, 29-37.
15. Helgadottir, A., Manolescu, A., Thorleifsson, G., Gretarsdottir, S., Jonsdottir, H., Thorsteinsdottir, U., Samani, N. J., Gudmundsson, G., Grant, S. F., Thorgeirsson, G., et al. (2004) Nat. Genet. 36, 233-239.
16. Aiello, R. J., Bourassa, P. A., Lindsey, S., Weng, W., Freeman, A. & Showell, H. J. (2002) Arterioscler. Thromb. Vasc. Biol. 22, 443-449.
17. Subbarao, K., Jala, V. R., Mathis, S., Suttles, J., Zacharias, W., Ahamed, J., Ali, H., Tseng, M. T. & Haribabu, B. (2004) Arterioscler. Thromb. Vasc. Biol. 24, 369-375.
18. Zhao, L., Moos, M. P., Grabner, R., Pedrono, F., Fan, J., Kaiser, B., John, N., Schmidt, S., Spanbroek, R., Lotzer, K., et al. (2004) Nat. Med. 10, 966-973.
19. Sakata, K., Dahlén, S. E. & Bäck, M. (2004) Br. J. Pharmacol. 141, 449-456.
20. Bäck, M., Qui, H., Haeggström, J. Z. & Sakata, K. (2004) Am. J. Physiol. 287, H419-H424.
21. Nomoto, A., Mutoh, S., Hagihara, H. & Yamaguchi, I. (1988) Atherosclerosis 72, 213-219.
22. Kondo, K., Umemura, K., Ohmura, T., Hashimoto, H. & Nakashima, M. (1998) Thromb. Haemost. 79, 635-639.
23. Bu, D. X., Erl, W., de Martin, R., Hansson, G. K. & Yan, Z. Q. (2005) FASEB J. 19, 1293-1295.
24. Birke, F. W., Meade, C. J., Anderskewitz, R., Speck, G. A. & Jennewein, H. M. (2001) J. Pharmacol. Exp. Ther. 297, 458-466.
25. Yan, Z. Q. & Hansson, G. K. (1998) Circ. Res. 82, 21-29.
26. Monaco, C., Andreakos, E., Kiriakidis, S., Mauri, C., Bicknell, C., Foxwell, B., Cheshire, N., Paleolog, E. & Feldmann, M. (2004) Proc. Natl. Acad. Sci. USA 101, 5634-5639.
27. Hamill, O. P., Marty, A., Neher, E., Sakmann, B. & Sigworth, F. J. (1981) Pflügers Arch. 391, 85-100.
28. Patton, C., Thompson, S. & Epel, D. (2004) Cell Calcium 35, 427-431.
29. Abedi, H. & Zachary, I. (1995) Cardiovasc. Res. 30, 544-556.
30. Gaudreau, R., Le Gouill, C., Venne, M. H., Stankova, J. & Rola-Pleszczynski, M. (2002) J. Biol. Chem. 277, 31567-31576.
31. Hwang, S. W., Cho, H., Kwak, J., Lee, S. Y., Kang, C. J., Jung, J., Cho, S., Min, K. H., Suh, Y. G., Kim, D. & Oh, U. (2000) Proc. Natl. Acad. Sci. USA 97, 6155-6160.
32. Obinata, H., Yokomizu, T., Shimizu, T. & Izumi, T. (2003) Biochem. Biophys. Res. Commun. 309, 114-119.
33. Chiang, N., Gronert, K., Clish, C. B., O'Brien, J. A., Freeman, M. W. & Serhan, C. N. (1999) J. Clin. Invest. 104, 309-316.
34. Valen, G., Yan, Z. Q. & Hansson, G. K. (2001) J. Am. Coll. Cardiol. 38, 307-314.
35. Staels, B., Koenig, W., Habib, A., Merval, R., Lebret, M., Torra, I. P., Delerive, P., Fadel, A., Chinetti, G., Fruchart, J. C., et al. (1998) Nature 393, 790-793.
36. Michel, J. B., De Roux, N., Plissonnier, D., Anidjar, S., Salzmann, J. L. & Levy, B. (1990) J. Cardiovasc. Pharmacol. 16, S4-S11.
37. Hansson, G. K. (2005) N. Engl. J. Med. 352, 1685-1695.
38. Hoffmann, R. & Mintz, G. S. (2000) Eur. Heart J. 21, 1739-1749.
39. Friedrich, E. B., Tager, A. M., Liu, E., Pettersson, A., Owman, C., Munn, L., Luster, A. D. & Gerszten, R. E. (2003) Arterioscler. Thromb. Vasc. Biol. 23, 1761-1767.
40. Huang, L., Zhao, A., Wong, F., Ayala, J. M., Struthers, M., Ujjainwalla, F., Wright, S. D., Springer, M. S., Evans, J. & Cui, J. (2004) Arterioscler. Thromb. Vasc. Biol. 24, 1-7.
41. Kato, K., Yokomizo, T., Izumi, T. & Shimizu, T. (2000) J. Exp. Med. 192, 413-420.