Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4

Development

Volumn 130, Issue 19, 2003, Pages 4539-4552

  Blackshear, Perry J ^a,b   Graves, Joan P ^a   Stumpo, Deborah J ^a   Cobos, Inma ^c   Rubenstein, John L R ^c   Zeldin, Darryl C ^a,b  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cortex; Hydrocephalus; Midline; Mouse; Regulatory factor X; Winged helix transcription factor

Indexed keywords

HEART ENZYME; REGULATOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RFX4; UNCLASSIFIED DRUG;

ADULTHOOD; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIRTH DEFECT; BRAIN; BRAIN AQUEDUCT; BRAIN DEVELOPMENT; BRAIN VENTRICLE; CEREBROSPINAL FLUID FLOW; CONTROLLED STUDY; EMBRYO; GENE DISRUPTION; GENE EXPRESSION; GENE INSERTION; GENE LOCUS; GENETIC LINE; GENETIC VARIABILITY; HEAD; HEART; HUMAN; HYDROCEPHALUS; INTRON; MESENCEPHALON; MOUSE; NEUROLOGIC DISEASE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGANOGENESIS; PERINATAL DEATH; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN FAMILY; REGULATORY MECHANISM; SUBCOMMISSURAL ORGAN; TISSUE SPECIFICITY; TRANSGENE;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BRAIN; DNA-BINDING PROTEINS; EMBRYO; HELIX-TURN-HELIX MOTIFS; HUMANS; HYDROCEPHALUS; IN SITU HYBRIDIZATION; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PHENOTYPE; PROTEIN ISOFORMS; SEQUENCE ALIGNMENT; TISSUE DISTRIBUTION; TRANSCRIPTION FACTORS;

ANIMALIA; INSERTION SEQUENCES; MAMMALIA;

EID: 0142074402     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.00661     Document Type: Article

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