Characterization of the Pal motifs in the upstream glucokinase promoter: Binding of a cell type-specific protein complex correlates with transcriptional activation

Molecular Endocrinology

Volumn 10, Issue 6, 1996, Pages 723-731

  Moates, J Michael ^a   Shelton, Kathy D ^a   Magnuson, Mark A ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GLUCOKINASE; PROTEIN;

ANIMAL CELL; ARTICLE; CELL TYPE; CERCOPITHECIDAE; CROSS LINKING; DNA PROTEIN COMPLEX; GENE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING;

3T3 CELLS; ANIMALS; BASE SEQUENCE; BINDING SITES; CRICETINAE; CROSS-LINKING REAGENTS; GLUCOKINASE; ISLETS OF LANGERHANS; LASERS; MICE; MUTATION; PITUITARY NEOPLASMS; PROMOTER REGIONS (GENETICS); PROTEINS; TRANS-ACTIVATION (GENETICS); TUMOR CELLS, CULTURED; ULTRAVIOLET RAYS;

EID: 0029938124     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.10.6.723     Document Type: Article

References (42)

1. Jetton TL, Liang Y, Pettepher CC, Zimmerman EC, Cox FG, Horvath K, Matchinsky FM, Magnuson MA 1994 Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut. J Biol Chem 269:3641-3654
2. Meglasson MD, Matschinsky FM 1986 Pancreatic islet glucose metabolism and regulation of insulin secretion. Diabetes Metab Rev 2:163-214
3. Matschinsky FM 1990 Glucokinase as glucose sensor and metabolic signal generator in pancreatic beta-cells and hepatocytes. Diabetes 39:647-652
4. Magnuson MA, Shelton KD 1989 An alternate promoter in the glucokinase gene is active in the pancreatic beta cell. J Biol Chem 264:15936-15942
5. Postic C, Niswender KD, Decaux J-F, Parsa R, Shelton KD, Gouhot B, Pettepher C, Granner DK, Girard J, Magnuson MA 1995 Cloning and characterization of the mouse glucokinase gene locus and identification of distal liver-specific DNase I hypersensitive sites. Genomics 29: 740-750
6. Hughes SD, Quaade C, Milburn JL, Cassidy L, Newgard CB 1991 Expression of normal and novel glucokinase mRNAs in anterior pituitary and islet cells. J Biol Chem 266:4521-4530
7. Liang Y, Jetton TL, Zimmerman E, Najafi H, Matschinsky FM, Magnuson MA 1991 Effects of alternate RNA splicing on glucokinase isoform activities in the pancreatic islet, liver, and pituitary. J Biol Chem 266:6999-7007
8. Leibiger B, Walther R, Leibiger IB 1994 The role of the proximal CTAAT-box of the rat glucokinase upstream promoter in transcriptional control in insulin-producing cells. Biol Chem Hoppe Seyler 375:93-98
9. Leibiger IB, Walther R, Pett U, Leibiger B 1994 Positive and negative regulatory elements are involved in transcriptional control of the rat glucokinase gene in the insulin producing cell line HIT M2.2.2. FEBS Lett 337: 161-166
10. Shelton KD, Franklin A, Khoor A, Beechem J, Magnuson MA 1992 Multiple elements in the upstream glucokinase promoter are necessary for transcription in insulinoma cells. Mol Cell Biol 12:4578-4589
11. Magnuson MA, Jetton TL 1993 Evolutionary conservation of elements in the upstream glucokinase promoter. Biochem Soc Trans 21:160-163
12. Leonard J, Peers B, Johnson T, Ferreri K, Lee S, Montminy MR 1993 Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells. Mol Endocrinol 7:1275-1283
13. Ohlsson H, Karlsson K, Edlund T 1993 IPF-1, a homeodomain-containing transactivator of the insulin gene. EMBO J 12:4251-4259
14. Miller CP, Robert E McGehee J, Habener JF 1994 IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene. EMBO J 13:1145-1156
15. Offield MF, Jetton TL, Labosky PA, Ray M, Stein R, Magnuson MA, Hogan BLM, CVEWright 1996 PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 122:983-995
16. Jonsson J, Carlsson L, Edlund T, Edlund H 1994 Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371:606-609
17. Peers B, Leonard J, Sharma S, Teitelman G, Montminy MR 1994 Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1. Mol Endocrinol 8:1798-1805
18. Peshavaria M, Gamer L, Henderson E, Teitelman G, Wright CVE, Stein R 1994 XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor. Mol Endocrinol 8:806-816
19. Jin WD, Boutillier A-L, Glucksman MJ, Salton SRJ, Loeffler J-P, Roberts JL 1994 Characterization of a corticotropin-releasing hormone-responsive element in the rat proopiomelanocortin gene promoter and molecular cloning of its binding protein. Mol Endocrinol 8:1377-1388
20. Furst P, Hu S, Hackett R, Hamer D 1988 Copper activates metallothionein gene transcription by altering the conformation of a specific DNA binding protein. Cell 55:705-717
21. Hockensmith JW, Kubasek WL, Evertsz EM, Mesner LD, vonHippel PH 1993 Laser cross-linking of proteins to nucleic acids II. Interactions of the bacteriophage T4 replication polymerase accessory proteins complex with DNA. J Biol Chem 21:15721-15730
22. Hockensmith JW, Kubasek WL, Vorachek WR, vonHippel PH 1993 Laser cross-linking of proteins to nucleic acids 1. Examining physical parameters of protein-nucleic acid complexes. J Biol Chem 268:15712-15720
23. Giguere V 1994 Retinoic acid receptors and cellular retinoid binding proteins: complex interplay in retinoid signaling. Endocr Rev 15:61-73
24. Glass CK 1994 Differential recognition of target genes by nuclear receptor monomers, dimers, and heterodimers. Endocr Rev 15:391-407
25. Latchman DS 1990 Eukaryotic transcription factors. Biochem J 270:281-289
26. Diamond MI, Miner JN, Yoshinaga SK, Yamamoto KR 1990 Transcriptiopn factor interactions: selectors of positive or negative regulation from a single DNA element. Science 249:1266-1272
27. Jones FS, Prediger EA, Bittner DA, DeRobertis EM, Edelman GM 1992 Cell adhesion molecules as targets for Hox genes: neural cell adhesion molecule promoter activity is modulated by cotransfection with Hox-2.5 and -2.4. Proc Natl Acid Sci 89:2086-2090
28. Schule R, Umesono K, Mangelsdorf DJ, Bolado J, Pike JW, Evans RM 1990 Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene. Cell 61:497-504
29. Cooney AJ, Leng X, Tsai SY, O'Malley BW, Tsai M-J 1993 Multiple mechanisms of chicken ovalbumin upstream promoter transcription factor-dependent repression of transactivation by the vitamin D, thyroid hormone, and retinoic acid receptors. J Biol Chem 268:4152-4160
30. Naar AM, Boutin J-M, Lipkin SM, Yu VC, Holloway JM, Glass CK, Rosenfeld MG 1991 The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors. Cell 65:1257-1279
31. Umesono K, Murakami KK, Thompson CC, Evans RM 1991 Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors. Cell 65:1255-1266
32. Harding HP, Lazar MA 1993 The orphan receptor Rev-ErbAα activates transcription via a novel response element. Mol Cell Biol 13:3113-3121
33. Wilson TE, Fahrner TJ, Johnston M, Milbrandt J 1991 Identification of the DNA binding site for NGFI-B by genetic selection in yeast. Science 252:1296-1300
34. Meyer TE, Habener JF 1993 Cyclic adenosine 3′,5′monophosphate response element binding protein (CREB) and related transcription-activating deoxyribonucleic acid-binding proteins. Endocr Rev 14:269-290
35. Lucas P, Granner DK 1992 Hormone response domains in gene transcription. Annu Rev Biochem 61:1131-1173
36. Kunkel TA 1985 Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc Natl Acad Sci USA 82:488-492
37. Chrapkiewicz NB, Davis CM, Chu D., Caldwell CM, Granner DK 1989 Rat gene 33: analysis of its structure, messenger RNA and basal promoter activity. Nucleic Acids Res 17:6651-6667
38. Edlund T, Walker MD, Barr PJ, Rutter WJ 1985 Cell-specific expression of the rat insulin gene: evidence for role of two distinct 5′ flanking elements. Science 230: 912-916
39. Santere RF, Cook RA, Crisel RMD, Sharp JD, Schmidt RJ, Williams DC, Wilson CP 1981 Insulin synthesis in a clonal cell line of simian virus 40-transformed hamster pancreatic beta cells. Proc Natl Acad Sci USA 78:4339-4343
40. Gumbiner B, Kelly RB 1982 Two distinct intracellular pathways transport secretory and membrane glycoproteins to the surface of pituitary tumor cells. Cell 28:51-59
41. Chu G, Hayakawa H, Berg P 1987 Electroporation for the efficient transfection of mammalian cells with DNA. Nucleic Acids Res 15:1311-1326
42. de Wet JR, Wood KV, DeLuca M, Helinski DR, Subramani S 1987 Firefly luciferase gene: structure and expression in mammalian cells. Mol Cell Biol 7:725-737