Pre-treatment of Syndrex® protects mice from becoming diabetic after streptozotocin injection

Fitoterapia

Volumn 81, Issue 5, 2010, Pages 403-412

  Dixit, P P ^a   Misar, A ^b   Mujumdar, A M ^b   Ghaskadbi, S ^a  

^a UNIVERSITY OF PUNE   (India)

^b AGHARKAR RESEARCH INSTITUTE   (India)

Author keywords

Antidiabetic; Antioxidant enzymes; Streptozotocin; Syndrex ; TBARS

Indexed keywords

ANTIOXIDANT; CATALASE; CHOLESTEROL; GLUCOSE; GLUTATHIONE REDUCTASE; INSULIN; STREPTOZOCIN; SUPEROXIDE DISMUTASE; SYNDREX; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACYLGLYCEROL; TRIGONELLA FOENUM GRAECUM EXTRACT; TRIGONELLINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; DRUG DOSE COMPARISON; FEEDING; FEMALE; FENUGREEK; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERGLYCEMIA; INSULIN TOLERANCE TEST; LIPID PEROXIDATION; LIVER HOMOGENATE; LUNG; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS; PRIORITY JOURNAL; SPLEEN; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DRUG ADMINISTRATION SCHEDULE; HYPOGLYCEMIC AGENTS; MICE; PHYTOTHERAPY; PLANT EXTRACTS; SEEDS; STREPTOZOCIN; TRIGONELLA;

ANIMALIA; MUS;

EID: 77954216211     PISSN: 0367326X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fitote.2009.11.011     Document Type: Article

References (39)

1. R.P. Robertson, and J.S. Harmon Glucose toxicity, and oxidative stress: a case of double jeopardy for the pancreatic islet beta cell, Diabetes Free Radic Biol Med 41 2006 177 184
2. M. Brownlee The pathophysiology of diabetic complications Diabetes 54 2005 1615 1625
3. A.C. Maritim, R.A. Sanders, and J.B. Watkins III Diabetes, oxidative stress, and antioxidants: a review J Biochem Mol Toxicol 17 2003 24 38 Review
4. L. Piconi, L. Quagliaro, and A. Ceriello Oxidative stress in diabetes Clin Chem Lab Med 41 2003 1144 1149 Review
5. E. Basch, C. Ulbricht, G. Kuo, P. Szapary, and M. Smith Therapeutic applications of fenugreek Altern Med Rev 81 2003 20 27
6. W.L. Xue, X.S. Li, J. Zhang, Y.H. Liu, Z.L. Wang, and R.J. Zhang Effect of Trigonella foenum-graecum (fenugreek) extract on blood glucose, blood lipid and hemorheological properties in streptozotocin-induced diabetic rats Asia Pac J Clin Nutr 16 2007 422 426
7. J.M. Hannan, L. Marenah, L. Ali, B. Rokeya, P.R. Flatt, and Y.H. Abdel-Wahab Insulin secretory actions of extracts of Asparagus racemosus root in perfused pancreas, isolated islets and clonal pancreatic beta-cells J Endocrinol 192 2007 159 168
8. B. Annida, and M.P.P. Stanely Supplementation of fenugreek leaves lower lipid profile in streptozotocin-induced diabetic rats J Med Food 7 2004 153 156
9. M.V. Vijaykumar, S. Singh, R.R. Chhipa, and M.K. Bhat The hypoglycemic activity of fenugreek extract is mediated through the stimulation of an insulin signaling pathway Br J Pharmacol 146 2005 41 48
10. ® has a strong antioxidant activity Eur J Pharmacol 581 2008 216 225
11. H. Kaneto, Y. Kajimoto, and J. Miyagawa Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity Diabetes 48 1999 2398 2406
12. C. Beauchamp, and I. Fridovich Superoxide dismutase: improved assays and an assay applicable to acrylamide gels Anal Biochem 44 1971 276 287
13. H.E. Aebi H.U. Bermeyer, Catalase Methods of enzymatic analysis volume 3 1983 Verlagchemie GmbH Weinhein 277 282
14. D.M. Goldberg, and R.J. Spooner Glutathione reductase H.U. Bermeyer, Methods of enzymatic analysis volume 3 1983 Verlagchemie GmbH Weinhein 258 265
15. R.A. Lawrence, and R.F. Burk Glutathione peroxidase activity in selenium deficient rat liver Biochem Biophys Res Commun 71 1976 952 958
16. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with the Folin Phenol reagent J Biol Chem 93 1951 265 275
17. R.L. Heath, and L. Packer Effect of light on lipid peroxidation in chloroplasts Biochem Biophys Res Commun 19 1965 716 720
18. H.Q. Zhao, Y. Qu, X.Y. Wang, X.Y. Lu, X.H. Zhang, and M. Hattori Determination of trigonelline by HPLC and study on its pharmacokinetics Yao Xue Xue Bao 38 2003 279 282
19. H.R. Fish, B. Chernow, and J.T. O'Brien Endocrine and neurophysiologic responses of the pituitary to insulin-induced hypoglycaemia: a review Metabolism 35 1986 763 780
20. A. Gidado, D.A. Ameh, and S.E. Atawodi Effect of Nauclea latifolia leaves aqueous extracts on blood glucose levels of normal and alloxan-induced diabetic rats Afr J Biotech 4 2005 91 93
21. R.C. Ruhe, and R.B. McDonald Use of antioxidant nutrients in the prevention and treatment of type 2 diabetes J Am Coll Nutr 20 2001 363S 369S
22. N. Houstis, E.D. Rosen, and E.S. Lander Reactive oxygen species play a causal role in multiple forms of insulin resistance Nature 440 2006 944 948
23. J.K. Grover, S. Yadav, and V. Vats Medicinal plants with anti- diabetic potential J Ethnopharmacol 81 2002 81 100
24. M. Modak, P. Dixit, J. Londhe, S. Ghaskadbi, and T.P.A. Devasagayam Indian herbs and herbal drugs used for the treatment of diabetes J Clin Biochem Nutr 40 2007 163 173
25. P.S.M. Prince, V.P. Menon, and G. Gunasekaran Hypolipidaemic action of Tinospora cordifolia roots in alloxan diabetic rats J Ethnopharmacol 64 1999 53 57
26. S. Mutalik, M. Chetana, B. Sulochana, P.U. Devi, and N. Udupa Effect of Dianex, a herbal formulation on experimentally induced diabetes mellitus Phytother Res 19 2005 409 415
27. G. Ribes, Y. Sauvaire, C. Da Costa, J.C. Baccou, and M.M. Loubatieres-Mariani Antidiabetic effects of subfractions from fenugreek seeds in diabetic dogs Proc Soc Exp Biol Med 182 1986 159 166
28. C.V. Anuradha, and P. Ravikumar Restoration on tissue antioxidants by fenugreek seeds (Trigonella Foenum graecum) in alloxan-diabetic rats Indian J Physiol Pharmacol 45 2001 408 420
29. T. Zia, S.N. Hasnain, and S.K. Hasan Evaluation of the oral hypoglycaemic effect of Trigonella foenum-graecum L. (methi) in normal mice J Ethnopharmacol 75 2001 191 195
30. S. Genet, R.K. Kale, and N.Z. Baquer Alterations in antioxidant enzymes and oxidative damage in experimental diabetic rat tissues: effect of vanadate and fenugreek (Trigonella foenum graecum) Mol Cell Biochem 236 2002 7 12
31. P. Dixit, S. Ghaskadbi, M. Hari, and T.P.A. Devasagayam Antioxidant properties of germinated fenugreek seeds Phytother Res 19 2005 977 983
32. B. Annida, and M.P.P. Stanely Supplementation of fenugreek leaves reduces oxidative stress in streptozotocin-induced diabetic rats J Med Food 8 2005 382 385
33. G. Valette, Y. Sauvaire, J.C. Baccou, and G. Ribes Hypocholesterolaemic effect of fenugreek seeds in dogs Atherosclerosis 50 1984 105 111
34. R. Rajalingam, N. Srinivasan, and P. Govindarajulu Effect of alloxan induced diabetes on lipid profiles in renal cortex and medulla of mature albino rats Indian J Exp Biol 31 1993 577 579
35. R.M. Pathak, S. Ansari, and A. Mahmood Changes in chemical composition of intestinal brush border membrane in alloxan induced chronic diabetes Indian J Exp Biol 19 1981 503 505
36. T. Szkudelski The mechanism of alloxan and streptozotocin action in β cells of the rat pancreas Physiol Res 50 2001 536 546
37. F. Amicarelli, A.M. Ragnelli, P. Aimola, A. Bonfigli, S. Colafarina, and C.D. Ilio Age dependent ultrastructural alterations and biochemical response of rat skeletal muscle after hypoxic or hyperoxic treatments Biochim Biophys Acta 1453 1999 105 114
38. J.S. Johansen, A.K. Harris, D.J. Rychly, and A. Ergul Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice Cardiovasc Diabetol 4 2005 5
39. A.M. Flammang, M.A. Cifone, G.L. Erexson, and L.F. Stankowski Jr. Genotoxicity testing of a fenugreek extract Food Chem Toxicol 42 2004 1769 1775