Communication between homologous alleles preserves genomic stability during V(D)J recombination

Nucleus

Volumn 1, Issue 1, 2010, Pages 23-29

  Brandt, Vicky L ^a   Hewitt, Susannah L ^a   Skok, Jane A ^a,b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Allelic exclusion; Atm; Genomic stability; Homologous pairing; Igh; Igk; Pericentromeric heterochromatin; Pericentromeric recruitment; Rag; V(D)j recombination

Indexed keywords

2 MORPHOLINO 6 (1 THIANTHRENYL) 4 PYRANONE; ANTIGEN; ATM PROTEIN; IMATINIB; IMMUNOGLOBULIN; RAG1 PROTEIN; RAG2 PROTEIN; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; GAMMA H2AX PROTEIN, MOUSE; GAMMA-H2AX PROTEIN, MOUSE; HISTONE; HOMEODOMAIN PROTEIN; PROTEIN SERINE THREONINE KINASE; RAG 1 PROTEIN; RAG-1 PROTEIN; TUMOR SUPPRESSOR PROTEIN; V(D)J RECOMBINATION ACTIVATING PROTEIN 2;

ALLELE; ARTICLE; ATAXIA TELANGIECTASIA; B LYMPHOCYTE; CENTROMERE; CHROMOSOME PAIRING; CHROMOSOME TRANSLOCATION; DNA CLEAVAGE; DNA DAMAGE; GENE EXPRESSION; GENE LOCUS; GENETIC RECOMBINATION; GENOMIC INSTABILITY; HETEROCHROMATIN; INCIDENCE; NONHUMAN; PROTEIN BINDING; RECEPTOR GENE; T LYMPHOCYTE; TRANSGENE; X CHROMOSOME; ANIMAL; CELL LINE; CHROMOSOME; DNA REPAIR; DRUG ANTAGONISM; GENETICS; METABOLISM; MOUSE; VDJ RECOMBINATION;

ALLELES; ANIMALS; CELL CYCLE PROTEINS; CELL LINE; CHROMOSOMES; DNA REPAIR; DNA-BINDING PROTEINS; GENOMIC INSTABILITY; HISTONES; HOMEODOMAIN PROTEINS; IMMUNOGLOBULINS; MICE; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS; V(D)J RECOMBINATION;

EID: 77954090889     PISSN: 19491034     EISSN: 19491042     Source Type: Journal    
DOI: 10.4161/nucl.1.1.10595     Document Type: Article

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