A 3D model of CYP1B1 explains the dominant 4-hydroxylation of estradiol

Journal of Chemical Information and Modeling

Volumn 50, Issue 6, 2010, Pages 1173-1178

  Itoh, Toshimasa ^a   Takemura, Hitomi ^b,c   Shimoi, Kayoko ^c   Yamamoto, Keiko ^a  

^a SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

^b MATSUMOTO UNIVERSITY   (Japan)

^c UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3D MODELING; CRYSTAL STRUCTURE;

AMINO ACID RESIDUES; HOMOLOGY MODELING; THREE-DIMENSIONAL STRUCTURE;

CATALYST ACTIVITY;

CYTOCHROME P 450 CYP1B1; CYTOCHROME P-450 CYP1B1; ESTRADIOL; UNSPECIFIC MONOOXYGENASE;

AMINO ACID SEQUENCE; ARTICLE; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; HUMAN; HYDROXYLATION; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; ARYL HYDROCARBON HYDROXYLASES; BIOCATALYSIS; ESTRADIOL; HUMANS; HYDROXYLATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

EID: 77954051873     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci1000554     Document Type: Article

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