Structure conservation in cytochromes P450

Proteins: Structure, Function and Genetics

Volumn 58, Issue 3, 2005, Pages 596-609

  Mestres, Jordi ^a  

^a UNIVERSITAT POMPEU FABRA   (Spain)

Author keywords

Comparative analysis; Drug metabolism; Homology modeling; Positional conservation indices; Structure super imposition

Indexed keywords

CARBON; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; CYTOCHROME P450 2B; CYTOCHROME P450 2B4; CYTOCHROME P450 2C; CYTOCHROME P450 2C19; CYTOCHROME P450 2C5; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; COMPARATIVE STUDY; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG METABOLISM; DRUG TOXICITY; ENZYME CONFORMATION; ENZYME METABOLISM; ENZYME STRUCTURE; PRIORITY JOURNAL; PROTEIN FAMILY; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ARYL HYDROCARBON HYDROXYLASES; BACTERIA; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 ENZYME SYSTEM; DATABASES, PROTEIN; DRUG DESIGN; FUNGI; HUMANS; MIXED FUNCTION OXYGENASES; MODELS, MOLECULAR; MODELS, STATISTICAL; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; NORMAL DISTRIBUTION; PROTEIN CONFORMATION; PROTEOMICS; SEQUENCE HOMOLOGY, AMINO ACID; SOFTWARE; STEROID 21-HYDROXYLASE; STEROID HYDROXYLASES; THERMODYNAMICS;

EID: 12944305735     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.20354     Document Type: Article

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