Effect of pathogenic mutations on the structure and dynamics of Alzheimer's Aβ42-amyloid oligomers

Journal of Molecular Modeling

Volumn 16, Issue 5, 2010, Pages 1011-1020

  Kassler, Kristin ^a   Horn, Anselm H C ^a   Sticht, Heinrich ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Energetic analysis; Fibrillation; Glutamate 22; Molecular dynamics; Oligomerisation; Protein interaction

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; OLIGOMER; AMYLOID; AMYLOID PRECURSOR PROTEIN; CELL SURFACE RECEPTOR; PROTEASE NEXINS;

ALZHEIMER DISEASE; ARTICLE; CHEMICAL STRUCTURE; COGNITIVE DEFECT; CONTROLLED STUDY; DELETION MUTANT; ENERGY TRANSFER; GENE DELETION; GENE MUTATION; HUMAN; MOLECULAR DYNAMICS; MOLECULAR STABILITY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN INTERACTION; RIGIDITY; STATIC ELECTRICITY; STRUCTURE ANALYSIS; WILD TYPE; CHEMISTRY; GENETICS; MUTATION;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PROTEIN PRECURSOR; HUMANS; MOLECULAR DYNAMICS SIMULATION; MUTATION; RECEPTORS, CELL SURFACE;

EID: 77953944835     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-009-0611-1     Document Type: Article

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