Unique physicochemical profile of β-amyloid peptide variant Aβ1-40E22G protofibrils: Conceivable neuropathogen in arctic mutant carriers

Journal of Molecular Biology

Volumn 339, Issue 1, 2004, Pages 145-159

  Paivio A ^a,b   Jarvet, J ^c   Graslund A ^c   Lannfelt, L ^d   Westlind Danielsson, A ^a,e  

^a KAROLINSKA INSTITUTE   (Sweden)

^b SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^c STOCKHOLM UNIVERSITY   (Sweden)

^d UPPSALA UNIVERSITY   (Sweden)

^e H LUNDBECK A S   (Denmark)

Author keywords

AD, Alzheimer's disease; ADDL, amyloid derived diffusible ligands; Alzheimer's disease; amyloid; Arctic mutation; A , amyloid; EM, electron microscopy; kinetics; protofibrils; PS, presenilin; APP, amyloid precursor protein

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; GLUTAMIC ACID; GLYCINE; ISOPROTEIN; OLIGOMER; PROTEIN PRECURSOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ARTICLE; BETA SHEET; CALIBRATION; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; CODON; CORRELATION ANALYSIS; GEL PERMEATION CHROMATOGRAPHY; GENE MUTATION; HYDROPHOBICITY; MOLECULAR SIZE; MOLECULAR WEIGHT; NEUROPATHOLOGY; PHYSICAL CHEMISTRY; POINT MUTATION; PRIORITY JOURNAL; PROTEIN VARIANT; QUALITATIVE ANALYSIS; RNA TRANSLATION;

EID: 2342652177     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.03.028     Document Type: Article

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