메뉴 건너뛰기




Volumn 3, Issue 2, 2010, Pages 90-101

Molecular mechanisms in aging and current strategies to counteract sarcopenia

Author keywords

Myostatin; Sarcopenia; Skeletal muscle; SRF; Testosterone

Indexed keywords

AMINO ACID; ATROGIN 1; BRANCHED CHAIN AMINO ACID; CREATINE; CREATINE MONOPHOSPHATE; CYCLOSPORIN A [3 N METHYL DEXTRO ALANINE 4 N ETHYLVALINE]; ESSENTIAL AMINO ACID; ESTROGEN; GROWTH HORMONE; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN; MUSCLE RING FINGER 1 PROTEIN; MYO 29; MYOSTATIN; NOTEXIN; PF 354; PROTEIN INHIBITOR; PROTEIN KINASE B; RECOMBINANT SOMATOMEDIN C; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SERUM RESPONSE FACTOR; SOMATOMEDIN C; TESTOSTERONE; TRICHOSTATIN A; UNCLASSIFIED DRUG; VALPROIC ACID;

EID: 77953745513     PISSN: 18746098     EISSN: 18746128     Source Type: Journal    
DOI: 10.2174/1874609811003020090     Document Type: Article
Times cited : (94)

References (178)
  • 1
    • 17144362903 scopus 로고    scopus 로고
    • Differences in size, strength, and power of upper and lower body muscle groups in young and older men
    • Candow DG and Chilibeck PD. Differences in size, strength, and power of upper and lower body muscle groups in young and older men. J Gerontol A Biol Sci Med Sci 2005; 60: 148-56.
    • (2005) J Gerontol a Biol Sci Med Sci , vol.60 , pp. 148-156
    • Candow, D.G.1    Chilibeck, P.D.2
  • 4
  • 5
    • 0030174928 scopus 로고    scopus 로고
    • Muscle mass, survival and the elderly ICU patient
    • Griffiths RD. Muscle mass, survival and the elderly ICU patient. Nutrition 1996; 12: 456-8.
    • (1996) Nutrition , vol.12 , pp. 456-458
    • Griffiths, R.D.1
  • 7
    • 0027565841 scopus 로고
    • Ageing and human muscle: Observations from Sweden
    • Lexell J. Ageing and human muscle: observations from Sweden. Can J Appl Physiol 1993; 18: 2-18.
    • (1993) Can J Appl Physiol , vol.18 , pp. 2-18
    • Lexell, J.1
  • 9
    • 0035736260 scopus 로고    scopus 로고
    • Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo
    • Bodine SC, Stitt TN, Gonzalez M, Kline WO, Stover GL, Bauerlein R, et al. Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat Cell Biol 2001; 3: 1014-9.
    • (2001) Nat Cell Biol , vol.3 , pp. 1014-1019
    • Bodine, S.C.1    Stitt, T.N.2    Gonzalez, M.3    Kline, W.O.4    Stover, G.L.5    Bauerlein, R.6
  • 10
    • 0037318822 scopus 로고    scopus 로고
    • Signalling pathways that mediate skeletal muscle hypertrophy and atrophy
    • Glass DJ. Signalling pathways that mediate skeletal muscle hypertrophy and atrophy. Nat Cell Biol 2003; 5: 87-90.
    • (2003) Nat Cell Biol , vol.5 , pp. 87-90
    • Glass, D.J.1
  • 12
    • 0028032355 scopus 로고
    • Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins
    • Terada N, Patel HR, Takase K, Kohno K, Nairn AC and Gelfand EW. Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins. Proc Natl Acad Sci USA 1994; 91: 11477-81.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11477-81
    • Terada, N.1    Patel, H.R.2    Takase, K.3    Kohno, K.4    Nairn, A.C.5    Gelfand, E.W.6
  • 13
    • 0035312747 scopus 로고    scopus 로고
    • Regulation of translation initiation by FRAP/mTOR
    • Gingras AC, Raught B and Sonenberg N. Regulation of translation initiation by FRAP/mTOR. Genes Dev 2001; 15: 807-26.
    • (2001) Genes Dev , vol.15 , pp. 807-826
    • Gingras, A.C.1    Raught, B.2    Sonenberg, N.3
  • 15
    • 4544298823 scopus 로고    scopus 로고
    • Assessment of biomarkers of protein anabolism in skeletal muscle during the life span of the rat: Sarcopenia despite elevated protein synthesis
    • Kimball SR, O'Malley JP, Anthony JC, Crozier SJ and Jefferson LS. Assessment of biomarkers of protein anabolism in skeletal muscle during the life span of the rat: sarcopenia despite elevated protein synthesis. Am J Physiol Endocrinol Metab 2004; 287: E772-80.
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • Kimball, S.R.1    O'Malley, J.P.2    Anthony, J.C.3    Crozier, S.J.4    Jefferson, L.S.5
  • 16
    • 39449100832 scopus 로고    scopus 로고
    • Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation
    • Léger B, Derave W, De Bock K, Hespel P and Russell AP. Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation. Rejuvenation Res 2008; 11: 163-75.
    • (2008) Rejuvenation Res , vol.11 , pp. 163-175
    • Léger, B.1    Derave, W.2    de Bock, K.3    Hespel, P.4    Russell, A.P.5
  • 17
    • 33646357762 scopus 로고    scopus 로고
    • Aging-sensitive cellular and molecular mechanisms associated with skeletal muscle hypertrophy
    • Haddad F and Adams GR. Aging-sensitive cellular and molecular mechanisms associated with skeletal muscle hypertrophy. J Appl Physiol 2006; 100: 1188-203.
    • (2006) J Appl Physiol , vol.100 , pp. 1188-1203
    • Haddad, F.1    Adams, G.R.2
  • 18
    • 33646474863 scopus 로고    scopus 로고
    • Age-associated decrease in contraction-induced activation of downstream targets of Akt/mTOR signaling in skeletal muscle
    • Funai K, Parkington JD, Carambula S and Fielding RA. Age-associated decrease in contraction-induced activation of downstream targets of Akt/mTOR signaling in skeletal muscle. Am J Physiol Regul Integr Comp Physiol 2006; 290: R1080-R6.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.290
    • Funai, K.1    Parkington, J.D.2    Carambula, S.3    Fielding, R.A.4
  • 19
    • 33745206561 scopus 로고    scopus 로고
    • Impaired overload-induced muscle growth is associated with diminished translational signaling in aged rat fast-twitch skeletal muscle
    • Thomson DM and Gordon SE. Impaired overload-induced muscle growth is associated with diminished translational signaling in aged rat fast-twitch skeletal muscle. J Physiol 2006; 574: 291-305.
    • (2006) J Physiol , vol.574 , pp. 291-305
    • Thomson, D.M.1    Gordon, S.E.2
  • 20
    • 0023411439 scopus 로고
    • Identification and purification of a polypeptide that binds to the c-fos serum response element
    • Treisman R. Identification and purification of a polypeptide that binds to the c-fos serum response element. EMBO J 1987; 6: 2711-7.
    • (1987) EMBO J , vol.6 , pp. 2711-2717
    • Treisman, R.1
  • 21
    • 33745152386 scopus 로고    scopus 로고
    • The myocardin family of transcriptional coactivators: Versatile regulators of cell growth, migration, and myogenesis
    • Pipes GC, Creemers EE and Olson EN. The myocardin family of transcriptional coactivators: versatile regulators of cell growth, migration, and myogenesis. Genes Dev 2006; 20: 1545-56.
    • (2006) Genes Dev , vol.20 , pp. 1545-1556
    • Pipes, G.C.1    Creemers, E.E.2    Olson, E.N.3
  • 22
    • 33747764164 scopus 로고    scopus 로고
    • New role for serum response factor in postnatal skeletal muscle growth and regeneration via the interleukin 4 and insulin-like growth factor 1 pathways
    • Charvet C, Houbron C, Parlakian A, Giordani J, Lahoute C, Bertrand A, et al. New role for serum response factor in postnatal skeletal muscle growth and regeneration via the interleukin 4 and insulin-like growth factor 1 pathways. Mol Cell Biol 2006; 26: 6664-74.
    • (2006) Mol Cell Biol , vol.26 , pp. 6664-6674
    • Charvet, C.1    Houbron, C.2    Parlakian, A.3    Giordani, J.4    Lahoute, C.5    Bertrand, A.6
  • 23
    • 0037294936 scopus 로고    scopus 로고
    • Serum response factor plays an important role in the mechanically overloaded plantaris muscle of rats
    • Sakuma K, Nishikawa J, Nakao R, Nakano H, Sano M and Yasuhara M. Serum response factor plays an important role in the mechanically overloaded plantaris muscle of rats. Histochem Cell Biol 2003; 119: 149-60.
    • (2003) Histochem Cell Biol , vol.119 , pp. 149-160
    • Sakuma, K.1    Nishikawa, J.2    Nakao, R.3    Nakano, H.4    Sano, M.5    Yasuhara, M.6
  • 24
    • 0035109446 scopus 로고    scopus 로고
    • Skeletal muscle focal adhesion kinase, paxillin, and serum response factor are loading dependent
    • Gordon SE, Flück M and Booth FW. Skeletal muscle focal adhesion kinase, paxillin, and serum response factor are loading dependent. J Appl Physiol 2001; 90: 1174-83.
    • (2001) J Appl Physiol , vol.90 , pp. 1174-1183
    • Gordon, S.E.1    Flück, M.2    Booth, F.W.3
  • 25
    • 0029872733 scopus 로고    scopus 로고
    • Expression and activity of serum response factor is required for expression of the muscle-determining factor MyoD in both dividing and differentiating mouse C2C12 myoblasts
    • Gauthier-Rouviére C, Vandromme M, Tuil D, Lautredou N, Morris M, Soulez M, et al. Expression and activity of serum response factor is required for expression of the muscle-determining factor MyoD in both dividing and differentiating mouse C2C12 myoblasts. Mol Biol Cell 1996; 7: 719-29.
    • (1996) Mol Biol Cell , vol.7 , pp. 719-729
    • Gauthier-Rouviére, C.1    Vandromme, M.2    Tuil, D.3    Lautredou, N.4    Morris, M.5    Soulez, M.6
  • 26
    • 4444276202 scopus 로고    scopus 로고
    • Marked reduction of focal adhesion kinase, serum response factor and myocyte enhancer factor 2C, but increase in RhoA and myostatin in the hindlimb dy mouse muscles
    • Sakuma K, Nakao R, Inashima S, Hirata M, Kubo T and Yasuhara M. Marked reduction of focal adhesion kinase, serum response factor and myocyte enhancer factor 2C, but increase in RhoA and myostatin in the hindlimb dy mouse muscles. Acta Neuropath (Berl) 2004; 108: 241-9.
    • (2004) Acta Neuropath (Berl) , vol.108 , pp. 241-249
    • Sakuma, K.1    Nakao, R.2    Inashima, S.3    Hirata, M.4    Kubo, T.5    Yasuhara, M.6
  • 28
    • 49649097995 scopus 로고    scopus 로고
    • Age-related reductions in expression of serum response factor and myocardin-related transcription factor A in mouse skeletal muscles
    • Sakuma K, Akiho M, Nakashima H, Akima H and Yasuhara M. Age-related reductions in expression of serum response factor and myocardin-related transcription factor A in mouse skeletal muscles. Biochim Biophys Acta Mol Basis Dis 2008; 1782: 453-61.
    • (2008) Biochim Biophys Acta Mol Basis Dis , vol.1782 , pp. 453-461
    • Sakuma, K.1    Akiho, M.2    Nakashima, H.3    Akima, H.4    Yasuhara, M.5
  • 29
    • 16244382549 scopus 로고    scopus 로고
    • Muscle-specific signaling mechanism that links actin dynamics to serum response factor
    • Kuwahara K, Barrientos T, Pipes GC, Li S and Olson EN. Muscle-specific signaling mechanism that links actin dynamics to serum response factor. Mol Cell Biol 2005; 25: 3173-81.
    • (2005) Mol Cell Biol , vol.25 , pp. 3173-3181
    • Kuwahara, K.1    Barrientos, T.2    Pipes, G.C.3    Li, S.4    Olson, E.N.5
  • 30
    • 0042691723 scopus 로고    scopus 로고
    • Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes
    • Cen B, Selvaraj A, Burgess RC, Hitzler JK, Ma Z, Morris SW, et al. Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes. Mol Cell Biol 2003; 23: 6597-608.
    • (2003) Mol Cell Biol , vol.23 , pp. 6597-6608
    • Cen, B.1    Selvaraj, A.2    Burgess, R.C.3    Hitzler, J.K.4    Ma, Z.5    Morris, S.W.6
  • 31
    • 0037069365 scopus 로고    scopus 로고
    • Potentiation of serum response factor activity by a family of myocardin-related transcription factors
    • Wang DZ, Li S, Hockemeyer D, Sutherland L, Wang Z, Schratt G, et al. Potentiation of serum response factor activity by a family of myocardin-related transcription factors. Proc Natl Acad Sci USA 2002; 99: 14855-60.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 14855-60
    • Wang, D.Z.1    Li, S.2    Hockemeyer, D.3    Sutherland, L.4    Wang, Z.5    Schratt, G.6
  • 32
    • 0033963218 scopus 로고    scopus 로고
    • Integrin signaling's potential for mediating gene expression in hypertrophying skeletal muscle
    • Carson JA and Wei L. Integrin signaling's potential for mediating gene expression in hypertrophying skeletal muscle. J Appl Physiol 2000; 88: 337-43.
    • (2000) J Appl Physiol , vol.88 , pp. 337-343
    • Carson, J.A.1    Wei, L.2
  • 33
    • 20644440418 scopus 로고    scopus 로고
    • The kinase domain of titin controls muscle gene expression and protein turnover
    • Lange S, Xiang F, Yakovenko A, Vihola A, Hackman P, Rostkova E, et al. The kinase domain of titin controls muscle gene expression and protein turnover. Science 2005; 308: 1599-603.
    • (2005) Science , vol.308 , pp. 1599-1603
    • Lange, S.1    Xiang, F.2    Yakovenko, A.3    Vihola, A.4    Hackman, P.5    Rostkova, E.6
  • 34
    • 65249095210 scopus 로고    scopus 로고
    • Regulation of STARS and its downstream targets suggest a novel pathway involved in human skeletal muscle hypertrophy and atrophy
    • Lamon S, Wallace MA, Léger B and Russell AP. Regulation of STARS and its downstream targets suggest a novel pathway involved in human skeletal muscle hypertrophy and atrophy. J Physiol 2009; 587: 1795-803.
    • (2009) J Physiol , vol.587 , pp. 1795-1803
    • Lamon, S.1    Wallace, M.A.2    Léger, B.3    Russell, A.P.4
  • 35
    • 0031010050 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
    • McPherron AC, Lawler AM and Lee SJ. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 1997; 387: 83-90.
    • (1997) Nature , vol.387 , pp. 83-90
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.J.3
  • 36
    • 0034704106 scopus 로고    scopus 로고
    • Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast differentiation
    • Thomas M, Langley B, Berry C, Sharma M, Kirk S, Bass J, et al. Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast differentiation. J Biol Chem 2000; 275: 40235-43.
    • (2000) J Biol Chem , vol.275 , pp. 40235-43
    • Thomas, M.1    Langley, B.2    Berry, C.3    Sharma, M.4    Kirk, S.5    Bass, J.6
  • 37
    • 0037147210 scopus 로고    scopus 로고
    • Myostatin inhibits myoblast differentiation by down-regulating MyoD expression
    • Langley B, Thomas M, Bishop A, Sharma M, Gilmour S and Kambadur R. Myostatin inhibits myoblast differentiation by down-regulating MyoD expression. J Biol Chem 2002; 277: 49831-40.
    • (2002) J Biol Chem , vol.277 , pp. 49831-40
    • Langley, B.1    Thomas, M.2    Bishop, A.3    Sharma, M.4    Gilmour, S.5    Kambadur, R.6
  • 38
    • 33947538814 scopus 로고    scopus 로고
    • Myostatin induces cyclin D1 degradation to cause cell cycle arrest through a phosphatidylinositol 3-kinase/AKT/GSK-3 pathway and is antagonized by insulin-like growth factor 1
    • Yang W, Zhang Y, Li Y, Wu Z and Zhu D. Myostatin induces cyclin D1 degradation to cause cell cycle arrest through a phosphatidylinositol 3-kinase/AKT/GSK-3 pathway and is antagonized by insulin-like growth factor 1. J Biol Chem 2007; 282: 3799-808.
    • (2007) J Biol Chem , vol.282 , pp. 3799-3808
    • Yang, W.1    Zhang, Y.2    Li, Y.3    Wu, Z.4    Zhu, D.5
  • 39
    • 33846332013 scopus 로고    scopus 로고
    • Regulation of myostatin expression and myoblast differentiation by FoxO and SMAD transcription factors
    • Allen DL and Unterman TG. Regulation of myostatin expression and myoblast differentiation by FoxO and SMAD transcription factors. Am J Physiol Cell Physiol 2007; 292: C188-C99.
    • (2007) Am J Physiol Cell Physiol , vol.292
    • Allen, D.L.1    Unterman, T.G.2
  • 40
    • 0033971745 scopus 로고    scopus 로고
    • Modulation of myostatin expression during modified muscle use
    • Wehling M, Cai B and Tidball JG. Modulation of myostatin expression during modified muscle use. FASEB J 2000; 14: 103-10.
    • (2000) FASEB J , vol.14 , pp. 103-110
    • Wehling, M.1    Cai, B.2    Tidball, J.G.3
  • 41
    • 0034595910 scopus 로고    scopus 로고
    • Differential adaptation of growth and differentiation factor 8/myostatin, fibroblast growth factor 6 and leukemia inhibitory factor in overloaded, regenerating, and denervated rat muscles
    • Sakuma K, Watanabe K, Sano M, Uramoto I and Totsuka T. Differential adaptation of growth and differentiation factor 8/myostatin, fibroblast growth factor 6 and leukemia inhibitory factor in overloaded, regenerating, and denervated rat muscles. Biochim Biophys Acta Mol Cell Res 2000; 1497: 77-88.
    • (2000) Biochim Biophys Acta Mol Cell Res , vol.1497 , pp. 77-88
    • Sakuma, K.1    Watanabe, K.2    Sano, M.3    Uramoto, I.4    Totsuka, T.5
  • 42
    • 69949135816 scopus 로고    scopus 로고
    • The adaptive responses in several mediators linked with hypertrophy and atrophy of skeletal muscle after lower limb unloading in humans
    • Sakuma K, Watanabe K, Hotta N, Koike T, Ishida K, Katayama K, et al. The adaptive responses in several mediators linked with hypertrophy and atrophy of skeletal muscle after lower limb unloading in humans. Acta Physiol(Oxf) 2009; 197: 151-9.
    • (2009) Acta Physiol(Oxf) , vol.197 , pp. 151-159
    • Sakuma, K.1    Watanabe, K.2    Hotta, N.3    Koike, T.4    Ishida, K.5    Katayama, K.6
  • 43
    • 13044265837 scopus 로고    scopus 로고
    • Organization of the human myostatin gene and expression in health men and HIV-infected men with muscle wasting
    • Gonzalez-Cadavid NF, Taylor WE, Yarasheski K, Sinha-Hikim I, Ma K, Ezzat S, et al. Organization of the human myostatin gene and expression in health men and HIV-infected men with muscle wasting. Proc Natl Acad Sci USA 1998; 95: 14938-43.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 14938-14943
    • Gonzalez-Cadavid, N.F.1    Taylor, W.E.2    Yarasheski, K.3    Sinha-Hikim, I.4    Ma, K.5    Ezzat, S.6
  • 44
    • 47949097215 scopus 로고    scopus 로고
    • Imbalance between pSmad3 and Notch induces CDK inhibitors is old muscle stem cells
    • Carlson ME, Hsu M and Conboy IM. Imbalance between pSmad3 and Notch induces CDK inhibitors is old muscle stem cells. Nature 2008; 454: 528-32.
    • (2008) Nature , vol.454 , pp. 528-532
    • Carlson, M.E.1    Hsu, M.2    Conboy, I.M.3
  • 46
    • 0030593939 scopus 로고    scopus 로고
    • Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway
    • Mitch WE and Goldberg AL. Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway. N Engl J Med 1996; 335: 1897-905.
    • (1996) N Engl J Med , vol.335 , pp. 1897-1905
    • Mitch, W.E.1    Goldberg, A.L.2
  • 47
    • 0347285363 scopus 로고    scopus 로고
    • Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
    • Lecker SH, Jagoe RT, Gilbert A, Gomes M, Baracos V, Bailey J, et al. Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. FASEB J 2004; 18: 39-51.
    • (2004) FASEB J , vol.18 , pp. 39-51
    • Lecker, S.H.1    Jagoe, R.T.2    Gilbert, A.3    Gomes, M.4    Baracos, V.5    Bailey, J.6
  • 48
    • 0035941020 scopus 로고    scopus 로고
    • Identification of ubiquitin ligases required for skeletal muscle atrophy
    • Bodine SC, Latres E, Baumhueter S, Lai VK, Nunez L, Clarke BA, et al. Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 2001; 294: 1704-8.
    • (2001) Science , vol.294 , pp. 1704-1708
    • Bodine, S.C.1    Latres, E.2    Baumhueter, S.3    Lai, V.K.4    Nunez, L.5    Clarke, B.A.6
  • 49
    • 11144356337 scopus 로고    scopus 로고
    • Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
    • Sandri M, Sandri C, Gilbert A, Skurk C, Calabria E, Picard A, et al. Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 2004; 117: 399-41.
    • (2004) Cell , vol.117 , pp. 399-341
    • Sandri, M.1    Sandri, C.2    Gilbert, A.3    Skurk, C.4    Calabria, E.5    Picard, A.6
  • 50
    • 2042425906 scopus 로고    scopus 로고
    • The IGF-I/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
    • Stitt TN, Drujan D, Clarke BA, Panaro F, Timofeyva Y, Kline WO, et al. The IGF-I/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol Cell 2004; 14: 395-403.
    • (2004) Mol Cell , vol.14 , pp. 395-403
    • Stitt, T.N.1    Drujan, D.2    Clarke, B.A.3    Panaro, F.4    Timofeyva, Y.5    Kline, W.O.6
  • 53
    • 25644432770 scopus 로고    scopus 로고
    • Contributions of the ubiquitin-proteasome pathway and apoptosis to human skeletal muscle wasting with age
    • Whitman SA, Wacker MJ, Richmond SR and Godard MP. Contributions of the ubiquitin-proteasome pathway and apoptosis to human skeletal muscle wasting with age. Pflügers Arch 2005; 450: 437-46.
    • (2005) Pflügers Arch , vol.450 , pp. 437-446
    • Whitman, S.A.1    Wacker, M.J.2    Richmond, S.R.3    Godard, M.P.4
  • 54
    • 0346041564 scopus 로고    scopus 로고
    • Transcriptional profiling identifies extensive downregulation of extracellular matrix gene expression in sarcopenic rat soleus muscle
    • Pattison JS, Folk LC, Madsen RW, Childs TE and Booth FW. Transcriptional profiling identifies extensive downregulation of extracellular matrix gene expression in sarcopenic rat soleus muscle. Physiol Genomics 2003; 15: 34-43.
    • (2003) Physiol Genomics , vol.15 , pp. 34-43
    • Pattison, J.S.1    Folk, L.C.2    Madsen, R.W.3    Childs, T.E.4    Booth, F.W.5
  • 55
    • 33748526240 scopus 로고    scopus 로고
    • Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat tibialis anterior muscle
    • Clavel S, Coldefy AS, Kurkdjian E, Salles J, Margaritis I and Derijard B. Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat tibialis anterior muscle. Mech Ageing Dev 2006; 127: 794-801.
    • (2006) Mech Ageing Dev , vol.127 , pp. 794-801
    • Clavel, S.1    Coldefy, A.S.2    Kurkdjian, E.3    Salles, J.4    Margaritis, I.5    Derijard, B.6
  • 56
    • 21244450623 scopus 로고    scopus 로고
    • Selective downregulation of ubiquitin conjugation cascade mRNA occurs in the senescent rat soleus muscle
    • DeRuisseau KC, Kavazis AN and Powers SK. Selective downregulation of ubiquitin conjugation cascade mRNA occurs in the senescent rat soleus muscle. Exp Gerontol 2005; 40: 526-31.
    • (2005) Exp Gerontol , vol.40 , pp. 526-531
    • Deruisseau, K.C.1    Kavazis, A.N.2    Powers, S.K.3
  • 57
    • 33746611524 scopus 로고    scopus 로고
    • Atrogin- 1/MAFbx and MuRF1 are downregulated in ageing-related loss of skeletal muscle
    • Edström E, Altun M, Hägglund M and Ulfhake B. Atrogin- 1/MAFbx and MuRF1 are downregulated in ageing-related loss of skeletal muscle. J Gerontol A Biol Sci Med Sci 2006; 61: 663-74.
    • (2006) J Gerontol a Biol Sci Med Sci , vol.61 , pp. 663-674
    • Edström, E.1    Altun, M.2    Hägglund, M.3    Ulfhake, B.4
  • 58
    • 33846015010 scopus 로고    scopus 로고
    • Rapid disuse and denervation atrophy involve transcriptional changes similar to those of muscle wasting during systemic diseases
    • Sacheck JM, Hyatt JP, Raffaello A, Jagoe RT, Roy RR, Edgerton VR, et al. Rapid disuse and denervation atrophy involve transcriptional changes similar to those of muscle wasting during systemic diseases. FASEB J 2007; 21: 140-55.
    • (2007) FASEB J , vol.21 , pp. 140-155
    • Sacheck, J.M.1    Hyatt, J.P.2    Raffaello, A.3    Jagoe, R.T.4    Roy, R.R.5    Edgerton, V.R.6
  • 59
    • 38049058773 scopus 로고    scopus 로고
    • Modulation of age-induced apoptotic signaling and cellular remodeling by exercise and calorie restriction in skeletal muscle
    • Marzetti E, Lawler JM, Hiona A, Manini T, Seo AY and Leeuwenburgh C. Modulation of age-induced apoptotic signaling and cellular remodeling by exercise and calorie restriction in skeletal muscle. Free Radic Biol Med 2008; 44: 160-8.
    • (2008) Free Radic Biol Med , vol.44 , pp. 160-168
    • Marzetti, E.1    Lawler, J.M.2    Hiona, A.3    Manini, T.4    Seo, A.Y.5    Leeuwenburgh, C.6
  • 60
    • 73349091842 scopus 로고    scopus 로고
    • The role of mitochondria in apoptosis
    • Wang C and Youle RJ. The role of mitochondria in apoptosis. Ann Rev Genet 2009; 43: 95-118.
    • (2009) Ann Rev Genet , vol.43 , pp. 95-118
    • Wang, C.1    Youle, R.J.2
  • 61
    • 50349084852 scopus 로고    scopus 로고
    • Mitochondria in skeletal muscle: Adaptable rheostats of apoptotic susceptibility
    • Adhihetty PJ, O'Leary MF and Hood DA. Mitochondria in skeletal muscle: adaptable rheostats of apoptotic susceptibility. Exerc Sport Sci Rev 2008; 36: 116-21.
    • (2008) Exerc Sport Sci Rev , vol.36 , pp. 116-121
    • Adhihetty, P.J.1    O'Leary, M.F.2    Hood, D.A.3
  • 63
    • 0347318125 scopus 로고    scopus 로고
    • Aging and lifelong calorie restriction result in adaptations of skeletal muscle apoptosis repressor, apoptosis-inducing factor, X-linked inhibitor of apoptosis, caspase-3, and caspase-12
    • Dirks AJ and Leeuwenburgh C. Aging and lifelong calorie restriction result in adaptations of skeletal muscle apoptosis repressor, apoptosis-inducing factor, X-linked inhibitor of apoptosis, caspase-3, and caspase-12. Free Radic Biol Med 2004; 36: 27-39.
    • (2004) Free Radic Biol Med , vol.36 , pp. 27-39
    • Dirks, A.J.1    Leeuwenburgh, C.2
  • 64
    • 25844520458 scopus 로고    scopus 로고
    • Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism
    • Jezek P and Hlavata L. Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism. Int J Biochem Cell Biol 2005; 37: 2478-503.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 2478-2503
    • Jezek, P.1    Hlavata, L.2
  • 65
    • 0031032817 scopus 로고    scopus 로고
    • Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
    • Yakes FM and Van HB. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc Natl Acad Sci USA 1997; 94: 514-9.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 514-519
    • Yakes, F.M.1    Van, H.B.2
  • 66
    • 0036790385 scopus 로고    scopus 로고
    • Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging
    • Wei YH and Lee HC. Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging. Exp Biol Med (Maywood) 2002; 227: 671-82.
    • (2002) Exp Biol Med (Maywood) , vol.227 , pp. 671-682
    • Wei, Y.H.1    Lee, H.C.2
  • 67
    • 0036089622 scopus 로고    scopus 로고
    • Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia
    • Bua EA, McKiernan SH, Eanagat J, McKenzie D and Aiken JM. Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia. J Appl Physiol 2002; 92: 2617-24.
    • (2002) J Appl Physiol , vol.92 , pp. 2617-2624
    • Bua, E.A.1    McKiernan, S.H.2    Eanagat, J.3    McKenzie, D.4    Aiken, J.M.5
  • 68
  • 69
    • 0035127889 scopus 로고    scopus 로고
    • Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia
    • Wanagat J, Cao Z, Pathare P and Aiken JM. Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia. FASEB J 2001; 15: 322-32.
    • (2001) FASEB J , vol.15 , pp. 322-332
    • Wanagat, J.1    Cao, Z.2    Pathare, P.3    Aiken, J.M.4
  • 70
    • 0032992534 scopus 로고    scopus 로고
    • Mitochondria in organismal aging and degeneration
    • Cortopassi GA and Wong A. Mitochondria in organismal aging and degeneration. Biochim Biophys Acta 1999; 1410: 183-93.
    • (1999) Biochim Biophys Acta , vol.1410 , pp. 183-193
    • Cortopassi, G.A.1    Wong, A.2
  • 72
    • 33646697753 scopus 로고    scopus 로고
    • Exercise training attenuates age-induced changes in apoptotic signaling in rat skeletal muscle
    • Song W, Kwak HB and Lawler JM. Exercise training attenuates age-induced changes in apoptotic signaling in rat skeletal muscle. Antioxid Redox Signal 2006; 8: 517-8.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 517-518
    • Song, W.1    Kwak, H.B.2    Lawler, J.M.3
  • 73
    • 0035881047 scopus 로고    scopus 로고
    • Timing of postexercise protein intake is important for muscle hypertrophy with resistance training in elderly humans
    • Esmarck B, Andersen JL, Olsen S, Richter EA, Mizuno M and Kjaer M. Timing of postexercise protein intake is important for muscle hypertrophy with resistance training in elderly humans. J Physiol 2001; 535: 301-11.
    • (2001) J Physiol , vol.535 , pp. 301-311
    • Esmarck, B.1    Andersen, J.L.2    Olsen, S.3    Richter, E.A.4    Mizuno, M.5    Kjaer, M.6
  • 76
    • 2542418311 scopus 로고    scopus 로고
    • Effects of resistance training on older adults
    • Hunter GR, McCarthy JP and Bamman MM. Effects of resistance training on older adults. Sports Med 2004; 34: 329-48.
    • (2004) Sports Med , vol.34 , pp. 329-348
    • Hunter, G.R.1    McCarthy, J.P.2    Bamman, M.M.3
  • 77
    • 33745813868 scopus 로고    scopus 로고
    • Myogenic gene expression at rest and after a bout of resistance exercise in young (18-30 yr) and old (80-89 yr) women
    • Raue U, Slivka D, Jemiolo B, Hollon C and Trappe S. Myogenic gene expression at rest and after a bout of resistance exercise in young (18-30 yr) and old (80-89 yr) women. J Appl Physiol 2006; 101: 53-9.
    • (2006) J Appl Physiol , vol.101 , pp. 53-59
    • Raue, U.1    Slivka, D.2    Jemiolo, B.3    Hollon, C.4    Trappe, S.5
  • 78
    • 34247123850 scopus 로고    scopus 로고
    • The anti-inflammatory effect of exercise: Its role in diabetes and cardiovascular disease control
    • Pedersen BK. The anti-inflammatory effect of exercise: its role in diabetes and cardiovascular disease control. Essay Biochem 2006; 42: 105-17.
    • (2006) Essay Biochem , vol.42 , pp. 105-117
    • Pedersen, B.K.1
  • 79
    • 14844311928 scopus 로고    scopus 로고
    • Resistance exercise training decreases oxidative damage to DNA and increases cytochrome oxidase activity in older adults
    • Parise G, Brose AN and Tarnopolsky MA. Resistance exercise training decreases oxidative damage to DNA and increases cytochrome oxidase activity in older adults. Exp Gerontol 2005; 40: 173-80.
    • (2005) Exp Gerontol , vol.40 , pp. 173-180
    • Parise, G.1    Brose, A.N.2    Tarnopolsky, M.A.3
  • 80
    • 0034001564 scopus 로고    scopus 로고
    • Resistance exercise acutely increases MHC and mixed muscle protein synthesis rates in 78-84 and 23-32 yr olds
    • Hasten DL, Pak-Loduca J, Obert KA and Yarasheski KE. Resistance exercise acutely increases MHC and mixed muscle protein synthesis rates in 78-84 and 23-32 yr olds. Am J Physiol Endocrinol Metab 2000; 278: E620-E6.
    • (2000) Am J Physiol Endocrinol Metab , vol.278
    • Hasten, D.L.1    Pak-Loduca, J.2    Obert, K.A.3    Yarasheski, K.E.4
  • 82
    • 0037444470 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase (MAPK) pathway activation: Effects of age and acute exercise on human skeletal muscle
    • Williamson D, Gallagher P, Harber M, Hollon C and Trappe S. Mitogen-activated protein kinase (MAPK) pathway activation: effects of age and acute exercise on human skeletal muscle. J Physiol 2003; 547: 977-87.
    • (2003) J Physiol , vol.547 , pp. 977-987
    • Williamson, D.1    Gallagher, P.2    Harber, M.3    Hollon, C.4    Trappe, S.5
  • 83
    • 72749098121 scopus 로고    scopus 로고
    • Translational signaling responses preceding resistance training-mediated myofibers hypertrophy in young and old humans
    • Mayhew DL, Kim JS, Cross JM and Bamman MM. Translational signaling responses preceding resistance training-mediated myofibers hypertrophy in young and old humans. J Appl Physiol 2009; 107: 1655-62.
    • (2009) J Appl Physiol , vol.107 , pp. 1655-1662
    • Mayhew, D.L.1    Kim, J.S.2    Cross, J.M.3    Bamman, M.M.4
  • 84
    • 33746691931 scopus 로고    scopus 로고
    • Efficacy of 3 day/wk resistance training on myofiber hypertrophy and myogenic mechanisms in young vs. older adults
    • Kosek DJ, Kim JS, Petrella JK, Cross JM and Bamman MM. Efficacy of 3 day/wk resistance training on myofiber hypertrophy and myogenic mechanisms in young vs. older adults. J Appl Physiol 2006; 101: 531-44.
    • (2006) J Appl Physiol , vol.101 , pp. 531-544
    • Kosek, D.J.1    Kim, J.S.2    Petrella, J.K.3    Cross, J.M.4    Bamman, M.M.5
  • 85
    • 47749099634 scopus 로고    scopus 로고
    • Myostatin as a therapeutic target for musculoskeletal disease
    • Bradley L, Yaworsky PJ and Walsh FS. Myostatin as a therapeutic target for musculoskeletal disease. Cell Mol Life Sci 2008; 65: 2119-24.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 2119-2124
    • Bradley, L.1    Yaworsky, P.J.2    Walsh, F.S.3
  • 87
    • 33747223762 scopus 로고    scopus 로고
    • Myostatin inhibition slows muscle atrophy in rodent models of amyotrophic lateral sclerosis
    • Holzbaur EL, Howland DS, Weber N, Wallace K, She Y, Kwak S, et al. Myostatin inhibition slows muscle atrophy in rodent models of amyotrophic lateral sclerosis. Neurobiol Dis 2006; 23: 697-707.
    • (2006) Neurobiol Dis , vol.23 , pp. 697-707
    • Holzbaur, E.L.1    Howland, D.S.2    Weber, N.3    Wallace, K.4    She, Y.5    Kwak, S.6
  • 89
    • 33749507982 scopus 로고    scopus 로고
    • Functional and morphological recovery of dystrophic muscles in mice treated with deacetylase inhibitors
    • Minetti GC, Colussi C, Adami R, Serral C, Mozzetta C, Parente V, et al. Functional and morphological recovery of dystrophic muscles in mice treated with deacetylase inhibitors. Nature Med 2006; 12: 1147-50.
    • (2006) Nature Med , vol.12 , pp. 1147-1150
    • Minetti, G.C.1    Colussi, C.2    Adami, R.3    Serral, C.4    Mozzetta, C.5    Parente, V.6
  • 90
    • 69249211187 scopus 로고    scopus 로고
    • Deacetylase inhibitors modulate the myostatin/follistatin axis without improving cachexia in tumor-bearing mice
    • Bonetto A, Penna F, Minero VG, Reffo P, Bonelli G, Baccino FM, et al. Deacetylase inhibitors modulate the myostatin/follistatin axis without improving cachexia in tumor-bearing mice. Curr Cancer Drug Targets 2009; 9: 608-16.
    • (2009) Curr Cancer Drug Targets , vol.9 , pp. 608-616
    • Bonetto, A.1    Penna, F.2    Minero, V.G.3    Reffo, P.4    Bonelli, G.5    Baccino, F.M.6
  • 93
    • 37349084557 scopus 로고    scopus 로고
    • Amino acid metabolism and regulatory effets in aging
    • Timmerman KL and Volpi E. Amino acid metabolism and regulatory effets in aging. Curr Opin Clin Nutr Metab Care 2008; 11: 45-9.
    • (2008) Curr Opin Clin Nutr Metab Care , vol.11 , pp. 45-49
    • Timmerman, K.L.1    Volpi, E.2
  • 94
    • 66149110988 scopus 로고    scopus 로고
    • Potential application of essential amino acid supplementation to treat sarcopenia in elderly people
    • Henderson GC, Irving BA and Nair KS. Potential application of essential amino acid supplementation to treat sarcopenia in elderly people. J Clin Endocrinol Metab 2009; 94: 1524-6.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 1524-1526
    • Henderson, G.C.1    Irving, B.A.2    Nair, K.S.3
  • 95
    • 58149133630 scopus 로고    scopus 로고
    • Dietary protein recommendations and the prevention of sarcopenia
    • Paddon-Jones D and Rasmussen BB. Dietary protein recommendations and the prevention of sarcopenia. Curr Opin Nutr Metab Care 2009; 12: 86-90.
    • (2009) Curr Opin Nutr Metab Care , vol.12 , pp. 86-90
    • Paddon-Jones, D.1    Rasmussen, B.B.2
  • 97
    • 38949126221 scopus 로고    scopus 로고
    • Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle
    • Dreyer HC, Drummond MJ, Pennings B, Fujita S, Glynn EL and Chinkes DL. Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle. Am J Physiol Endocr Metab 2008; 294: E392-E400.
    • (2008) Am J Physiol Endocr Metab , vol.294
    • Dreyer, H.C.1    Drummond, M.J.2    Pennings, B.3    Fujita, S.4    Glynn, E.L.5    Chinkes, D.L.6
  • 98
    • 29244439931 scopus 로고    scopus 로고
    • A leucine-supplemented diet restores the defective postprandial inhibition of proteasome-dependent proteolysis in aged rat skeletal muscle
    • Combaret L, Dardevet D, Rieu I, Pouch M-N, Béchet D, Taillandier D, et al. A leucine-supplemented diet restores the defective postprandial inhibition of proteasome-dependent proteolysis in aged rat skeletal muscle. J Physiol 2005; 569: 489-99.
    • (2005) J Physiol , vol.569 , pp. 489-499
    • Combaret, L.1    Dardevet, D.2    Rieu, I.3    Pouch, M.-N.4    Béchet, D.5    Taillandier, D.6
  • 99
    • 45149131733 scopus 로고    scopus 로고
    • Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging
    • Drummond MJ, Dreyer HC, Pennings B, Fry CS, Dhanani S, Dillon EL, et al. Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging. J Appl Physiol 2008; 104: 1452-61.
    • (2008) J Appl Physiol , vol.104 , pp. 1452-1461
    • Drummond, M.J.1    Dreyer, H.C.2    Pennings, B.3    Fry, C.S.4    Dhanani, S.5    Dillon, E.L.6
  • 101
    • 0036305414 scopus 로고    scopus 로고
    • Oral amino-acid provision does not affect muscle strength or size gains in older men
    • Godard MP, Williamson DL and Trappe SW. Oral amino-acid provision does not affect muscle strength or size gains in older men. Med Sci Sports Exerc 2002; 34: 1126-31.
    • (2002) Med Sci Sports Exerc , vol.34 , pp. 1126-1131
    • Godard, M.P.1    Williamson, D.L.2    Trappe, S.W.3
  • 102
    • 0031979765 scopus 로고    scopus 로고
    • High-protein meals do not enhance myofibrillar synthesis after resistance exercise in 62- to 75-yr-old men and women
    • Welle S and Thornton CA. High-protein meals do not enhance myofibrillar synthesis after resistance exercise in 62- to 75-yr-old men and women. Am J Physiol Endocrinol Metab 1998; 274: E677-E83.
    • (1998) Am J Physiol Endocrinol Metab , vol.274
    • Welle, S.1    Thornton, C.A.2
  • 103
    • 33745853476 scopus 로고    scopus 로고
    • A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly
    • Katsanos CS, Kobayashi H, Sheffield-Moore M, Aarsland A and Wolfe RR. A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly. Am J Physiol Endocrinol Metab 2006; 291: E381-E7.
    • (2006) Am J Physiol Endocrinol Metab , vol.291
    • Katsanos, C.S.1    Kobayashi, H.2    Sheffield-Moore, M.3    Aarsland, A.4    Wolfe, R.R.5
  • 104
    • 44449084604 scopus 로고    scopus 로고
    • Nutritional supplements with oral amino acid mixtures increases whole-body lean mass and insulin sensitivity in elderly subjects with sarcopenia
    • Solerte SB, Gazzaruso C, Bonacasa R, Rondanelli M, Zamboni M, Basso C, et al. Nutritional supplements with oral amino acid mixtures increases whole-body lean mass and insulin sensitivity in elderly subjects with sarcopenia. Am J Cardiol 2008; 101(suppl): 69E-77E.
    • (2008) Am J Cardiol , vol.101 , Issue.SUPPL.
    • Solerte, S.B.1    Gazzaruso, C.2    Bonacasa, R.3    Rondanelli, M.4    Zamboni, M.5    Basso, C.6
  • 105
    • 66149141889 scopus 로고    scopus 로고
    • Amino acid supplementation increases lean body mass, basal muscle protein synthesis, and insulin-like growth factor-I expression in older women
    • Dillon EL, Sheffield-Moore M, Paddon-Jones D, Gilkison C, Sanford AP, Casperson SL, et al. Amino acid supplementation increases lean body mass, basal muscle protein synthesis, and insulin-like growth factor-I expression in older women. J Clin Endocrinol Metab 2009; 94: 1630-7.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 1630-1637
    • Dillon, E.L.1    Sheffield-Moore, M.2    Paddon-Jones, D.3    Gilkison, C.4    Sanford, A.P.5    Casperson, S.L.6
  • 106
    • 65549171522 scopus 로고    scopus 로고
    • Long-term leucine supplementation does not increase muscle mass or strength in healthy elderly men
    • Verhoeven S, Vanschoonbeek K, Verdijk LB, Koopman R, Wodzig WK, Dendale P, et al. Long-term leucine supplementation does not increase muscle mass or strength in healthy elderly men. Am J Clin Nutr 2009; 89: 1468-75.
    • (2009) Am J Clin Nutr , vol.89 , pp. 1468-1475
    • Verhoeven, S.1    Vanschoonbeek, K.2    Verdijk, L.B.3    Koopman, R.4    Wodzig, W.K.5    Dendale, P.6
  • 107
    • 33750102079 scopus 로고    scopus 로고
    • Co-ingestion of protein and leucine stimulates muscle protein synthesis rates to the same extent in young and elderly lean men
    • Koopman R, Verdijk L, Manders RJ, Gijsen AP, Gorselink M, Pijpers E, et al. Co-ingestion of protein and leucine stimulates muscle protein synthesis rates to the same extent in young and elderly lean men. Am J Clin Nutr 2006; 84: 623-32.
    • (2006) Am J Clin Nutr , vol.84 , pp. 623-632
    • Koopman, R.1    Verdijk, L.2    Manders, R.J.3    Gijsen, A.P.4    Gorselink, M.5    Pijpers, E.6
  • 108
    • 38949086515 scopus 로고    scopus 로고
    • Co-ingestion of leucine with protein does not further augment post-exercise muscle protein synthesis rates in elderly men
    • Koopman R, Verdijk LB, Beelen M, Gorselink M, Kruseman AN, Wagenmakers AJ, et al. Co-ingestion of leucine with protein does not further augment post-exercise muscle protein synthesis rates in elderly men. Br J Nutr 2008; 99: 571-80
    • (2008) Br J Nutr , vol.99 , pp. 571-580
    • Koopman, R.1    Verdijk, L.B.2    Beelen, M.3    Gorselink, M.4    Kruseman, A.N.5    Wagenmakers, A.J.6
  • 109
    • 59649122217 scopus 로고    scopus 로고
    • Protein supplementation before and ater exercise does not further augment skeletal muscle hypertrophy after resistance training in elderly men
    • Verdijk LB, Jonkers RA, Gleeson BG, Beelen M, Meijer K, Savelberg HH, et al. Protein supplementation before and ater exercise does not further augment skeletal muscle hypertrophy after resistance training in elderly men. Am J Clin Nutr 2009; 89: 608-16.
    • (2009) Am J Clin Nutr , vol.89 , pp. 608-616
    • Verdijk, L.B.1    Jonkers, R.A.2    Gleeson, B.G.3    Beelen, M.4    Meijer, K.5    Savelberg, H.H.6
  • 110
    • 27244443774 scopus 로고    scopus 로고
    • Postmenopausal hormone therapy and body composition- a substudy of the estrogen plus progestin trial of the Women's Health Iitiative
    • Chen Z, Bassford T, Green SB, Cauley JA, Jackson RD, LaCroix AZ, et al. Postmenopausal hormone therapy and body composition- a substudy of the estrogen plus progestin trial of the Women's Health Iitiative. Am J Clin Nutr 2005; 82: 651-6.
    • (2005) Am J Clin Nutr , vol.82 , pp. 651-656
    • Chen, Z.1    Bassford, T.2    Green, S.B.3    Cauley, J.A.4    Jackson, R.D.5    Lacroix, A.Z.6
  • 111
    • 70350506343 scopus 로고    scopus 로고
    • Oestradiol and SERM treatments influence oestrogen receptor coregulator gene expression in human skeletal muscle cells
    • Dieli-Conwright CM, Spektor TM, Rice JC and Schroeder ET. Oestradiol and SERM treatments influence oestrogen receptor coregulator gene expression in human skeletal muscle cells. Acta Physiol (Oxf) 2009; 197: 187-96.
    • (2009) Acta Physiol (Oxf) , vol.197 , pp. 187-196
    • Dieli-Conwright, C.M.1    Spektor, T.M.2    Rice, J.C.3    Schroeder, E.T.4
  • 113
    • 0030912617 scopus 로고    scopus 로고
    • Testosterone and the aging male
    • Tenover JL. Testosterone and the aging male. J Androl 1997; 18: 103-6.
    • (1997) J Androl , vol.18 , pp. 103-106
    • Tenover, J.L.1
  • 114
    • 33645274937 scopus 로고    scopus 로고
    • Drug insight: Testosterone and selective androgen receptor modulators as anabolic therapies for physical dysfunction in chronic illness and ageing
    • Bhasin S, Calof O, Storer TW, Lee M, Mazer N, Jasuja R, et al. Drug insight: testosterone and selective androgen receptor modulators as anabolic therapies for physical dysfunction in chronic illness and ageing. Nat Clin Pract Endocrinol Metab 2006; 2: 146-59.
    • (2006) Nat Clin Pract Endocrinol Metab , vol.2 , pp. 146-159
    • Bhasin, S.1    Calof, O.2    Storer, T.W.3    Lee, M.4    Mazer, N.5    Jasuja, R.6
  • 115
    • 0034456450 scopus 로고    scopus 로고
    • Transdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men. Testosterone gel study group
    • Wang C, Swedloff RS, Iranmanesh A, Dobs A, Snyder PJ, Cunningham G, et al. Transdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men. Testosterone gel study group. J Clin Endocrinol Metab 2000; 85: 2839-53.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2839-2853
    • Wang, C.1    Swedloff, R.S.2    Iranmanesh, A.3    Dobs, A.4    Snyder, P.J.5    Cunningham, G.6
  • 116
    • 0033983480 scopus 로고    scopus 로고
    • Testosterone replacement and resistance exercise in HIV-infected men with weight loss and low testosterone levels
    • Bhasin S, Storer TW, Javenbakht M, Berman N, Yarasheski KE, Phillips J, et al. Testosterone replacement and resistance exercise in HIV-infected men with weight loss and low testosterone levels. JAMA 2005; 283: 763-70.
    • (2005) JAMA , vol.283 , pp. 763-770
    • Bhasin, S.1    Storer, T.W.2    Javenbakht, M.3    Berman, N.4    Yarasheski, K.E.5    Phillips, J.6
  • 117
    • 0033807039 scopus 로고    scopus 로고
    • Androgen deficiency in aging men: Role of testosterone replacement therapy
    • Morley JE and Perry HM, 3rd. Androgen deficiency in aging men: role of testosterone replacement therapy. J Lab Clin Med 2000; 135: 370-8.
    • (2000) J Lab Clin Med , vol.135 , pp. 370-378
    • Morley, J.E.1    Perry 3rd., H.M.2
  • 119
    • 33747641590 scopus 로고    scopus 로고
    • Effects of testosterone supplementation on skeletal muscle fiber hypertrophy and satellite cells in community-dwelling older men
    • Sinha-Hikim I, Cornford M, Gaytan H, Lee ML and Bhasin S. Effects of testosterone supplementation on skeletal muscle fiber hypertrophy and satellite cells in community-dwelling older men. J Clin Endocrinol Metab 2006; 91: 3024-33.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 3024-3033
    • Sinha-Hikim, I.1    Cornford, M.2    Gaytan, H.3    Lee, M.L.4    Bhasin, S.5
  • 120
    • 0344827208 scopus 로고    scopus 로고
    • Notch-mediated restoration of regenerative potential to aged muscle
    • Conboy IM, Conboy MJ, Smythe GM and Rando TA. Notch-mediated restoration of regenerative potential to aged muscle. Science 2003; 302: 1575-7.
    • (2003) Science , vol.302 , pp. 1575-1577
    • Conboy, I.M.1    Conboy, M.J.2    Smythe, G.M.3    Rando, T.A.4
  • 122
    • 20044388344 scopus 로고    scopus 로고
    • Older men are as responsive as young men to the anabolic effects of graded doses of testosterone on the skeletal muscle
    • Bhasin S, Woodhouse L, Casaburi R, Singh AB, Mac RP, Lee M, et al. Older men are as responsive as young men to the anabolic effects of graded doses of testosterone on the skeletal muscle. J Clin Endocrinol Metab 2005; 90: 678-88.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 678-688
    • Bhasin, S.1    Woodhouse, L.2    Casaburi, R.3    Singh, A.B.4    Mac, R.P.5    Lee, M.6
  • 123
    • 0029907306 scopus 로고    scopus 로고
    • Growth hormone and the insulin-like growth factor system in myogenesis
    • Florini JR, Ewton DZ and Coolican SA. Growth hormone and the insulin-like growth factor system in myogenesis. Endocr Rev 1996; 17: 481-517.
    • (1996) Endocr Rev , vol.17 , pp. 481-517
    • Florini, J.R.1    Ewton, D.Z.2    Coolican, S.A.3
  • 125
    • 0036153329 scopus 로고    scopus 로고
    • Regulation of IGF-I mRNA and signal transducers and activators of transcription-3 and -5 (Stat-3 and -5) by GH in C2C12 myoblasts
    • Frost RA, Nystrom GJ and Lang CH. Regulation of IGF-I mRNA and signal transducers and activators of transcription-3 and -5 (Stat-3 and -5) by GH in C2C12 myoblasts. Endocrinology 2002; 143: 492-503.
    • (2002) Endocrinology , vol.143 , pp. 492-503
    • Frost, R.A.1    Nystrom, G.J.2    Lang, C.H.3
  • 126
    • 33646562823 scopus 로고    scopus 로고
    • Growth hormone promotes skeletal muscle cell fusion independent of insulin-like growth factor 1 up-regulation
    • Sotiropoulos A, Ohanna M, Kedzia C, Menon RK, Kopchick JJ, Kelly PA, et al. Growth hormone promotes skeletal muscle cell fusion independent of insulin-like growth factor 1 up-regulation. Proc Natl Acad Sci USA 2006; 103: 7315-20.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7315-7320
    • Sotiropoulos, A.1    Ohanna, M.2    Kedzia, C.3    Menon, R.K.4    Kopchick, J.J.5    Kelly, P.A.6
  • 127
    • 54449085789 scopus 로고    scopus 로고
    • Modulation of GH/IGF-I axis: Potential strategies to counteract sarcopenia in older adults
    • Giovannini S, Marzetti E, Borst SE and Leeuwenburgh C. Modulation of GH/IGF-I axis: Potential strategies to counteract sarcopenia in older adults. Mech Ageing Dev 2008; 129: 593-601.
    • (2008) Mech Ageing Dev , vol.129 , pp. 593-601
    • Giovannini, S.1    Marzetti, E.2    Borst, S.E.3    Leeuwenburgh, C.4
  • 128
    • 0033800076 scopus 로고    scopus 로고
    • Growth hormone and mild exercise in combination increases markedly muscle mass and tetanic tension in old rats
    • Andersen NB, Andreassen TT, Orskov H and Oxlund H. Growth hormone and mild exercise in combination increases markedly muscle mass and tetanic tension in old rats. Eur J Endocrinol 2000; 143: 409-18.
    • (2000) Eur J Endocrinol , vol.143 , pp. 409-418
    • Andersen, N.B.1    Andreassen, T.T.2    Orskov, H.3    Oxlund, H.4
  • 129
    • 20244372225 scopus 로고    scopus 로고
    • Growth hormone and sex steroid administration in healthy aged women and men: A randomized controlled trial
    • Blackman MR, Sorkin JD, Munzer T, Bellantoni MF, Busby-Whitehead J, Stevens TE, et al. Growth hormone and sex steroid administration in healthy aged women and men: a randomized controlled trial. JAMA 2002; 288: 2282-92.
    • (2002) JAMA , vol.288 , pp. 2282-2292
    • Blackman, M.R.1    Sorkin, J.D.2    Munzer, T.3    Bellantoni, M.F.4    Busby-Whitehead, J.5    Stevens, T.E.6
  • 130
    • 0036174075 scopus 로고    scopus 로고
    • GH administration changes myosin heavy chain isoforms in skeletal muscle but does not augment muscle strength or hypertrophy, either alone or combined with resistance exercise training in healthy elderly men
    • Lange KH, Andersen JL, Beyer N, Isaksson F, Larsson B, Rasmussen MH, et al. GH administration changes myosin heavy chain isoforms in skeletal muscle but does not augment muscle strength or hypertrophy, either alone or combined with resistance exercise training in healthy elderly men. J Clin Endocrinol Metab 2002; 87: 513-23.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 513-523
    • Lange, K.H.1    Andersen, J.L.2    Beyer, N.3    Isaksson, F.4    Larsson, B.5    Rasmussen, M.H.6
  • 131
  • 132
    • 33847638108 scopus 로고    scopus 로고
    • The role of the insulin-like growth factor 1 (IGF-1) in skeletal muscle physiology
    • Philippou A, Maridaki M, Halapas A and Koutsilieris M. The role of the insulin-like growth factor 1 (IGF-1) in skeletal muscle physiology. In Vivo 2007; 21: 45-54.
    • (2007) In Vivo , vol.21 , pp. 45-54
    • Philippou, A.1    Maridaki, M.2    Halapas, A.3    Koutsilieris, M.4
  • 133
    • 69949091564 scopus 로고    scopus 로고
    • Role of IGF-I in skeletal muscle mass maintenance
    • Clemmons DR. Role of IGF-I in skeletal muscle mass maintenance. Trends Endocrinol Metab 2009; 20: 349-56.
    • (2009) Trends Endocrinol Metab , vol.20 , pp. 349-356
    • Clemmons, D.R.1
  • 134
    • 0029040848 scopus 로고
    • Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofibers hypertrophy in transgenic mice
    • Coleman ME, DeMayo F, Yin KC, Lee HM, Geske R, Montgomery C, et al. Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofibers hypertrophy in transgenic mice. J Biol Chem 1995; 270: 12109-16.
    • (1995) J Biol Chem , vol.270 , pp. 12109-12116
    • Coleman, M.E.1    Demayo, F.2    Yin, K.C.3    Lee, H.M.4    Geske, R.5    Montgomery, C.6
  • 135
    • 0035136062 scopus 로고    scopus 로고
    • Localized Igf-I transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle
    • Musaró A, McCullagh K, Paul A, Houghton L, Dobrowolny G, Molinaro M, et al. Localized Igf-I transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle. Nat Genet 2001; 27: 195-200.
    • (2001) Nat Genet , vol.27 , pp. 195-200
    • Musaró, A.1    McCullagh, K.2    Paul, A.3    Houghton, L.4    Dobrowolny, G.5    Molinaro, M.6
  • 136
    • 0036544519 scopus 로고    scopus 로고
    • Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice
    • Barton ER, Morris L, Musaró A, Rosenthal N and Sweeney HL. Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice. J Cell Biol 2002; 157: 137-48.
    • (2002) J Cell Biol , vol.157 , pp. 137-148
    • Barton, E.R.1    Morris, L.2    Musaró, A.3    Rosenthal, N.4    Sweeney, H.L.5
  • 137
    • 0032416479 scopus 로고    scopus 로고
    • Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function
    • Barton-Davis ER, Shoturma DI, Musaró A, Rosenthal N and Sweeney HL. Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function. Proc Natl Acad Sci USA 1998; 95: 15603-7.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15603-15607
    • Barton-Davis, E.R.1    Shoturma, D.I.2    Musaró, A.3    Rosenthal, N.4    Sweeney, H.L.5
  • 138
    • 33747724209 scopus 로고    scopus 로고
    • Systemic administration of IGF-I enhances oxidative status and reduces contraction-induced injury in skeletal muscles of mdx dystrophic mice
    • Schertzer JD, Ryall JG and Lynch GS. Systemic administration of IGF-I enhances oxidative status and reduces contraction-induced injury in skeletal muscles of mdx dystrophic mice. Am J Physiol Endocrinol Metab 2006; 291: E499-E505.
    • (2006) Am J Physiol Endocrinol Metab , vol.291
    • Schertzer, J.D.1    Ryall, J.G.2    Lynch, G.S.3
  • 139
    • 4243086931 scopus 로고    scopus 로고
    • Administration of insulin- like growth factor-I improves fatigue resistance of skeletal muscles from dystrophic mdx mice
    • Gregorevic P, Plant DR and Lynch GS. Administration of insulin- like growth factor-I improves fatigue resistance of skeletal muscles from dystrophic mdx mice. Muscle Nerve 2004; 30: 295-304.
    • (2004) Muscle Nerve , vol.30 , pp. 295-304
    • Gregorevic, P.1    Plant, D.R.2    Lynch, G.S.3
  • 141
    • 0028219050 scopus 로고
    • Insulin-like growth factor-1 and insulin resistance in skeletal muscles of adult and old rats
    • Dardevet D, Sornet C, Attaix D, Baracos VE and Grizard J. Insulin-like growth factor-1 and insulin resistance in skeletal muscles of adult and old rats. Endocrinology 1994; 134: 1475-84.
    • (1994) Endocrinology , vol.134 , pp. 1475-1484
    • Dardevet, D.1    Sornet, C.2    Attaix, D.3    Baracos, V.E.4    Grizard, J.5
  • 142
    • 0347318125 scopus 로고    scopus 로고
    • Aging and lifelong calorie restriction result in adaptations of skeletal muscle apoptosis repressor, apoptosis-inducing factor, X-linked inhibitor of apoptosis, caspase-3, and caspase-12
    • Dirks AJ and Leeuwenburgh C. Aging and lifelong calorie restriction result in adaptations of skeletal muscle apoptosis repressor, apoptosis-inducing factor, X-linked inhibitor of apoptosis, caspase-3, and caspase-12. Free Radic Biol Med 2004; 36: 27-39.
    • (2004) Free Radic Biol Med , vol.36 , pp. 27-39
    • Dirks, A.J.1    Leeuwenburgh, C.2
  • 144
    • 0035098360 scopus 로고    scopus 로고
    • Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice
    • Weindruch R, Kayo T, Lee CK and Prolla TA. Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice. J Nutr 2001; 131: 918S-23S.
    • (2001) J Nutr , vol.131
    • Weindruch, R.1    Kayo, T.2    Lee, C.K.3    Prolla, T.A.4
  • 145
    • 16344385647 scopus 로고    scopus 로고
    • Muscle fiber specific apoptosis and TNF- alpha signaling in sarcopenia are attenuated by life-long calorie restriction
    • Phillips T and Leeuwenburgh C. Muscle fiber specific apoptosis and TNF- alpha signaling in sarcopenia are attenuated by life-long calorie restriction. FASEB J 2005; 95: 668-70.
    • (2005) FASEB J , vol.95 , pp. 668-670
    • Phillips, T.1    Leeuwenburgh, C.2
  • 146
    • 0345708253 scopus 로고    scopus 로고
    • Life-long calorie restriction in Fischer 344 rats attenuates age-related loss in skeletal muscle-specific force and reduces extracellular space
    • Payne AM, Dodds SL and Leeuwenburgh C. Life-long calorie restriction in Fischer 344 rats attenuates age-related loss in skeletal muscle-specific force and reduces extracellular space. J Appl Physiol 2003; 95: 2554-62.
    • (2003) J Appl Physiol , vol.95 , pp. 2554-2562
    • Payne, A.M.1    Dodds, S.L.2    Leeuwenburgh, C.3
  • 147
    • 1842544684 scopus 로고    scopus 로고
    • Effects of short- and medium-term calorie restriction on muscle mitochondrial protein leak and reactive oxygen species production
    • Bevilacqua L, Ramsey JJ, Hagopian K, Weindruch R and Harper M-E, et al. Effects of short- and medium-term calorie restriction on muscle mitochondrial protein leak and reactive oxygen species production. Am J Physiol Endocrinol Metab 2004; 286: E852-E61.
    • (2004) Am J Physiol Endocrinol Metab , vol.286
    • Bevilacqua, L.1    Ramsey, J.J.2    Hagopian, K.3    Weindruch, R.4    Harper, M.-E.5
  • 148
    • 0030982145 scopus 로고    scopus 로고
    • Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle
    • Aspnes LE, Lee CM, Weindruch R, Chung SS, Roecker EB and Aiken JM. Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle. FASEB J 1997; 11: 573-81.
    • (1997) FASEB J , vol.11 , pp. 573-581
    • Aspnes, L.E.1    Lee, C.M.2    Weindruch, R.3    Chung, S.S.4    Roecker, E.B.5    Aiken, J.M.6
  • 149
    • 33746655748 scopus 로고    scopus 로고
    • No decline in skeletal muscle oxidative capacity with aging in long-term calorically restricted rats: Effects are independent of mitochondrial DNA integrity
    • Baker DJ, Betik AC, Krause DJ and Hepple RT. No decline in skeletal muscle oxidative capacity with aging in long-term calorically restricted rats: Effects are independent of mitochondrial DNA integrity. J Gerontol A Biol Sci Med Sci 2006; 61: 675-84.
    • (2006) J Gerontol a Biol Sci Med Sci , vol.61 , pp. 675-684
    • Baker, D.J.1    Betik, A.C.2    Krause, D.J.3    Hepple, R.T.4
  • 150
    • 60549115947 scopus 로고    scopus 로고
    • Changes in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restriction
    • Marzetti E, Carter CS, Wohlgemuth SE, Lees HA, Giovannini S anderson B, et al. Changes in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restriction. Mech Ageing Dev 2009; 130: 272-80.
    • (2009) Mech Ageing Dev , vol.130 , pp. 272-280
    • Marzetti, E.1    Carter, C.S.2    Wohlgemuth, S.E.3    Lees, H.A.4    Giovannini, S.5    Anderson, B.6
  • 152
    • 28244466940 scopus 로고    scopus 로고
    • Caloric restriction in humans: Potential pitfalls and health concerns
    • Dirks AJ and Leeuwenburgh C. Caloric restriction in humans: Potential pitfalls and health concerns. Mech Ageing Dev 2006; 127: 1-7.
    • (2006) Mech Ageing Dev , vol.127 , pp. 1-7
    • Dirks, A.J.1    Leeuwenburgh, C.2
  • 153
    • 0842326603 scopus 로고    scopus 로고
    • Age-related changes in glutathione availability and skeletal muscle carbonyl content in healthy rats
    • Mosoni L, Breuille D, Buffiere C, Obled C and Mirand PP. Age-related changes in glutathione availability and skeletal muscle carbonyl content in healthy rats. Exp Gerontol 2004; 39: 203-10.
    • (2004) Exp Gerontol , vol.39 , pp. 203-210
    • Mosoni, L.1    Breuille, D.2    Buffiere, C.3    Obled, C.4    Mirand, P.P.5
  • 155
    • 34548833829 scopus 로고    scopus 로고
    • Role of oxidative stress from mitochondria on aging and cancer
    • Ishii N. Role of oxidative stress from mitochondria on aging and cancer. Cornea 2008; 26: S3-S9.
    • (2008) Cornea , vol.26
    • Ishii, N.1
  • 157
    • 37349105620 scopus 로고    scopus 로고
    • Effect of lifelong coenzyme Q10 supplementation on age-related oxidative stress and mitochondrial function in liver and skeletal muscle of rats fed on a polyunsaturated fatty acid (PUFA)-rich diet
    • Ochoa JJ, Quiles JL, López-Frías M, Huertas JR and Mataix J. Effect of lifelong coenzyme Q10 supplementation on age-related oxidative stress and mitochondrial function in liver and skeletal muscle of rats fed on a polyunsaturated fatty acid (PUFA)-rich diet. J Gerontol A Biol Sci Med Sci 2007; 62: 1211-8.
    • (2007) J Gerontol a Biol Sci Med Sci , vol.62 , pp. 1211-1218
    • Ochoa, J.J.1    Quiles, J.L.2    López-Frías, M.3    Huertas, J.R.4    Mataix, J.5
  • 158
    • 22544480331 scopus 로고    scopus 로고
    • Effect of antioxidant-enriched diets on glutathione redox status in tissue homogenates and mitochondria of the senescence accerelated mouse
    • Rebrin I, Zicker S, Wedekind KJ, Paetau-Robinson I, Packer L and Sohal RS. Effect of antioxidant-enriched diets on glutathione redox status in tissue homogenates and mitochondria of the senescence accerelated mouse. Free Radic Biol Med 2005; 39: 549-57.
    • (2005) Free Radic Biol Med , vol.39 , pp. 549-557
    • Rebrin, I.1    Zicker, S.2    Wedekind, K.J.3    Paetau-Robinson, I.4    Packer, L.5    Sohal, R.S.6
  • 159
    • 0033253468 scopus 로고    scopus 로고
    • Dietary creatine monohydrate supplementation
    • Jacobs I. Dietary creatine monohydrate supplementation. Can J Appl Physiol 1999; 24: 503-14.
    • (1999) Can J Appl Physiol , vol.24 , pp. 503-514
    • Jacobs, I.1
  • 160
    • 0032932504 scopus 로고    scopus 로고
    • Muscle creatine phosphate in gyrate atrophy of the choroids and retina with hyperornithinaemia-clues to pathogenesis
    • Heinanen K, Nanto-Salonen K, Komu M, Erkintalo M, Heinonen OJ, Pulkki K, et al. Muscle creatine phosphate in gyrate atrophy of the choroids and retina with hyperornithinaemia-clues to pathogenesis. Eur J Clin Invest 1999; 29: 426-31.
    • (1999) Eur J Clin Invest , vol.29 , pp. 426-431
    • Heinanen, K.1    Nanto-Salonen, K.2    Komu, M.3    Erkintalo, M.4    Heinonen, O.J.5    Pulkki, K.6
  • 161
    • 0029853255 scopus 로고    scopus 로고
    • Creatine depletion elicits structural, biochemical, and physiological adaptations in rat costal diaphragm
    • Levine S, Tikunov B, Henson D, LaManca J and Sweeney HL. Creatine depletion elicits structural, biochemical, and physiological adaptations in rat costal diaphragm. Am J Physiol 1996; 271: C1480-C6.
    • (1996) Am J Physiol , vol.271
    • Levine, S.1    Tikunov, B.2    Henson, D.3    Lamanca, J.4    Sweeney, H.L.5
  • 162
    • 0031727607 scopus 로고    scopus 로고
    • Effects of creatine monohydrate ingestion in sedentary and weight-trained older adults
    • Bermon S, Venembre P, Sachet C, Valour S and Dolisi C. Effects of creatine monohydrate ingestion in sedentary and weight-trained older adults. Acta Physiol Scand 1998; 164: 147-55.
    • (1998) Acta Physiol Scand , vol.164 , pp. 147-155
    • Bermon, S.1    Venembre, P.2    Sachet, C.3    Valour, S.4    Dolisi, C.5
  • 163
  • 164
    • 0037240189 scopus 로고    scopus 로고
    • Creatine supplementation enhances isometric strength and body composition improvements following strength exercise training in older adults
    • Brose A, Parise G and Tarnopolsky MA. Creatine supplementation enhances isometric strength and body composition improvements following strength exercise training in older adults. J Gerontol A Biol Sci Med Sci 2003; 58: 11-9.
    • (2003) J Gerontol a Biol Sci Med Sci , vol.58 , pp. 11-19
    • Brose, A.1    Parise, G.2    Tarnopolsky, M.A.3
  • 169
    • 0035887283 scopus 로고    scopus 로고
    • Oral creatine supplementation facilitates the rehabilitation of disuse atrophy and alters the expression of muscle myogenic factors in humans
    • Hespel P, OP't Eijnde B, Van Leemputte M, Ursø B, Greenhalf PL, Labarque V, et al. Oral creatine supplementation facilitates the rehabilitation of disuse atrophy and alters the expression of muscle myogenic factors in humans. J Physiol 2001; 536: 625-33.
    • (2001) J Physiol , vol.536 , pp. 625-633
    • Hespel, P.1    Op't Eijnde, B.2    van Leemputte, M.3    Ursø, B.4    Greenhalf, P.L.5    Labarque, V.6
  • 170
    • 33745049977 scopus 로고    scopus 로고
    • Creatine supplementation augments the increase in satellite cell and myonuclei number in human skeletal muscle induced by strength training
    • Olsen S, Aagaard P, Kadi F, Tufekovic G, Verney J, Olsen JL, et al. Creatine supplementation augments the increase in satellite cell and myonuclei number in human skeletal muscle induced by strength training. J Physiol 2006; 573: 525-34.
    • (2006) J Physiol , vol.573 , pp. 525-534
    • Olsen, S.1    Aagaard, P.2    Kadi, F.3    Tufekovic, G.4    Verney, J.5    Olsen, J.L.6
  • 171
    • 0034875340 scopus 로고    scopus 로고
    • Effects of acute creatine monohydrate supplementation on leucine kinetics and mixed-muscle protein synthesis
    • Parise G, Mihic S, MacLennan D, Yarasheski KE and Tarnopolsky MA. Effects of acute creatine monohydrate supplementation on leucine kinetics and mixed-muscle protein synthesis. J Appl Physiol 2001; 91: 1041-7.
    • (2001) J Appl Physiol , vol.91 , pp. 1041-1047
    • Parise, G.1    Mihic, S.2    Maclennan, D.3    Yarasheski, K.E.4    Tarnopolsky, M.A.5
  • 173
    • 0033958628 scopus 로고    scopus 로고
    • Acute creatine supplementation in older men
    • Rawson ES and Clarkson PM. Acute creatine supplementation in older men. Int J Sports Med 2000; 21: 71-5.
    • (2000) Int J Sports Med , vol.21 , pp. 71-75
    • Rawson, E.S.1    Clarkson, P.M.2
  • 174
    • 15844407874 scopus 로고    scopus 로고
    • Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
    • Nakagawa T, Shimizu S, Watanabe T, Yamaguchi O, Otsu K, Yamagata H, et al. Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 2005; 434: 652-8.
    • (2005) Nature , vol.434 , pp. 652-658
    • Nakagawa, T.1    Shimizu, S.2    Watanabe, T.3    Yamaguchi, O.4    Otsu, K.5    Yamagata, H.6
  • 175
    • 24744460273 scopus 로고    scopus 로고
    • Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia
    • Schinzel AC, Takeuchi O, Huang Z, Fisher JK, Zhou Z, Rubens J, et al. Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia. Proc Natl Acad Sci USA 2005; 102: 12005-10.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 12005-10
    • Schinzel, A.C.1    Takeuchi, O.2    Huang, Z.3    Fisher, J.K.4    Zhou, Z.5    Rubens, J.6
  • 176
    • 41849118741 scopus 로고    scopus 로고
    • Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy
    • Millay DP, Sargent MA, Osinska H, Baines CP, Elisabeth RB, Vuagniaux G, et al. Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy. Nat Med 2008; 14: 442-7.
    • (2008) Nat Med , vol.14 , pp. 442-447
    • Millay, D.P.1    Sargent, M.A.2    Osinska, H.3    Baines, C.P.4    Elisabeth, R.B.5    Vuagniaux, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.