메뉴 건너뛰기




Volumn 420, Issue 6914, 2002, Pages 418-421

Functional improvement of dystrophic muscle by myostatin blockade

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; DISEASES; DRUG THERAPY; ENZYMES; GENES; MUTAGENESIS;

EID: 0037191752     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01154     Document Type: Article
Times cited : (750)

References (30)
  • 1
    • 0031010050 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mass in mice by a new TGF-β superfamily member
    • McPherron, A. C., Lawler, A. M. & Lee, S. J. Regulation of skeletal muscle mass in mice by a new TGF-β superfamily member. Nature 387, 83-90 (1997).
    • (1997) Nature , vol.387 , pp. 83-90
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.J.3
  • 2
    • 0034716993 scopus 로고    scopus 로고
    • Dominant negative myostatin produces hypertrophy without hyperplasia in muscle
    • Zhu, X., Hadhazy, M., Wehling, M., Tidball, J. G. & McNally, E. M. Dominant negative myostatin produces hypertrophy without hyperplasia in muscle. FEBS Lett. 474, 71-75 (2000).
    • (2000) FEBS Lett. , vol.474 , pp. 71-75
    • Zhu, X.1    Hadhazy, M.2    Wehling, M.3    Tidball, J.G.4    McNally, E.M.5
  • 3
    • 16944364045 scopus 로고    scopus 로고
    • A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle
    • Grobet, L. et al. A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle. Nature Genet. 17, 71-74 (1997).
    • (1997) Nature Genet. , vol.17 , pp. 71-74
    • Grobet, L.1
  • 5
    • 0023091942 scopus 로고
    • The mutant mdx: Inherited myopathy in the mouse. Morphological studies of nerves, muscles and end-plates
    • Torres, L. F. & Duchen, L. W. The mutant mdx: Inherited myopathy in the mouse. Morphological studies of nerves, muscles and end-plates. Brain 110, 269-299 (1987).
    • (1987) Brain , vol.110 , pp. 269-299
    • Torres, L.F.1    Duchen, L.W.2
  • 6
    • 0023636746 scopus 로고
    • Conservation of the Duchenne muscular dystrophy gene in mice and humans
    • Hoffman, E. P., Monaco, A. P., Feener, C. C. & Kunkel, L. M. Conservation of the Duchenne muscular dystrophy gene in mice and humans. Science 238, 347-350 (1987).
    • (1987) Science , vol.238 , pp. 347-350
    • Hoffman, E.P.1    Monaco, A.P.2    Feener, C.C.3    Kunkel, L.M.4
  • 7
    • 0023614188 scopus 로고
    • Dystrophin: The protein product of the Duchenne muscular dystrophy locus
    • Hoffman, E. P., Brown, R. H. Jr & Kunkel, L. M. Dystrophin: The protein product of the Duchenne muscular dystrophy locus. Cell 51, 919-928 (1987).
    • (1987) Cell , vol.51 , pp. 919-928
    • Hoffman, E.P.1    Brown R.H., Jr.2    Kunkel, L.M.3
  • 8
    • 0023910734 scopus 로고
    • The mdx mouse skeletal muscle myopathy. 1. A histological, morphometric and biochemical investigation
    • Coulton, G. R., Morgan, J. E., Partridge, T. A. & Sloper, J. C. The mdx mouse skeletal muscle myopathy. 1. A histological, morphometric and biochemical investigation. Neuropathol. Appl. Neurobiol. 14, 53-70 (1988).
    • (1988) Neuropathol. Appl. Neurobiol. , vol.14 , pp. 53-70
    • Coulton, G.R.1    Morgan, J.E.2    Partridge, T.A.3    Sloper, J.C.4
  • 9
    • 0034883063 scopus 로고    scopus 로고
    • GDF-8 propeptide binds to GDF-8 and antagonizes biological activity by inhibiting GDF-8 receptor binding
    • Thies, R. S. et al. GDF-8 propeptide binds to GDF-8 and antagonizes biological activity by inhibiting GDF-8 receptor binding. Growth Factors 18, 251-259 (2001).
    • (2001) Growth Factors , vol.18 , pp. 251-259
    • Thies, R.S.1
  • 10
    • 4243448874 scopus 로고    scopus 로고
    • Transcriptional changes arising from in vivo inhibition of myostatin
    • Jalenak, M. et al. Transcriptional changes arising from in vivo inhibition of myostatin. J. Neurol. Sci. 199 (suppl)., S83 (2002).
    • (2002) J. Neurol. Sci. , vol.199 , Issue.SUPPL.
    • Jalenak, M.1
  • 11
    • 0035694910 scopus 로고    scopus 로고
    • Smad regulation in TGF-beta signal transduction
    • Moustakas, A., Souchelnytskyi, S. & Heldin, C. H. Smad regulation in TGF-beta signal transduction. J. Cell Sci. 114, 4359-4369 (2001).
    • (2001) J. Cell Sci. , vol.114 , pp. 4359-4369
    • Moustakas, A.1    Souchelnytskyi, S.2    Heldin, C.H.3
  • 12
    • 0035979253 scopus 로고    scopus 로고
    • Regulation of myostatin activity and muscle growth
    • Lee, S. J. & McPherron, A. C. Regulation of myostatin activity and muscle growth. Proc. Natl Acad. Sci. USA 98, 9306-9311 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 9306-9311
    • Lee, S.J.1    McPherron, A.C.2
  • 16
    • 0028817970 scopus 로고
    • Visualization of dystrophic muscle fibers in mdx mouse by vital staining with Evans blue: Evidence of apoptosis in dystrophin-deficient muscle
    • Matsuda, R., Nishikawa, A. & Tanaka, H. Visualization of dystrophic muscle fibers in mdx mouse by vital staining with Evans blue: Evidence of apoptosis in dystrophin-deficient muscle. J. Biochem. (Tokyo) 118, 959-964 (1995).
    • (1995) J. Biochem. (Tokyo) , vol.118 , pp. 959-964
    • Matsuda, R.1    Nishikawa, A.2    Tanaka, H.3
  • 17
    • 0036197455 scopus 로고    scopus 로고
    • Continuous myonuclear addition to single extraocular myofibers in uninjured adult rabbits
    • McLoon, L. K. & Wirtschafter, J. D. Continuous myonuclear addition to single extraocular myofibers in uninjured adult rabbits. Muscle Nerve 25, 348-358 (2002).
    • (2002) Muscle Nerve , vol.25 , pp. 348-358
    • McLoon, L.K.1    Wirtschafter, J.D.2
  • 18
    • 0036359149 scopus 로고    scopus 로고
    • Expression profiting reveals metabolic and structural components of extraocular muscles
    • Fischer, M. D. et al. Expression profiting reveals metabolic and structural components of extraocular muscles. Physiol. Genom. 9, 71-84 (2002).
    • (2002) Physiol. Genom. , vol.9 , pp. 71-84
    • Fischer, M.D.1
  • 19
    • 0026419948 scopus 로고
    • The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy
    • Stedman, H. H. et al. The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy. Nature 352, 536-539 (1991).
    • (1991) Nature , vol.352 , pp. 536-539
    • Stedman, H.H.1
  • 20
    • 0025167294 scopus 로고
    • Identification of a chromosome 6-encoded dystrophin 6-encoded dystrophin-related protein
    • Khurana, T. S., Hoffman, E. P. & Kunkel, L. M. Identification of a chromosome 6-encoded dystrophin 6-encoded dystrophin-related protein. J. Biol. Chem 265, 16717-16720 (1990).
    • (1990) J. Biol. Chem. , vol.265 , pp. 16717-16720
    • Khurana, T.S.1    Hoffman, E.P.2    Kunkel, L.M.3
  • 21
    • 0025932274 scopus 로고
    • Immunolocalization and developmental expression of dystrophin related protein in skeletal muscle
    • Khurana, T. S. et al. Immunolocalization and developmental expression of dystrophin related protein in skeletal muscle. Neuromuscul. Disord. 1, 185-194 (1991).
    • (1991) Neuromuscul. Disord. , vol.1 , pp. 185-194
    • Khurana, T.S.1
  • 24
    • 0027248618 scopus 로고
    • Increased susceptibility of EDL muscles from mdx mice to damage induced by contractions with stretch
    • Moens, P., Baatsen, P. H. & Marechal, G. Increased susceptibility of EDL muscles from mdx mice to damage induced by contractions with stretch. J. Muscle Res. Cell Motil. 14, 446-451 (1993).
    • (1993) J. Muscle Res. Cell Motil. , vol.14 , pp. 446-451
    • Moens, P.1    Baatsen, P.H.2    Marechal, G.3
  • 26
    • 0029906168 scopus 로고    scopus 로고
    • Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene
    • Tinsley, J. M. et al. Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene. Nature 384, 349-353 (1996).
    • (1996) Nature , vol.384 , pp. 349-353
    • Tinsley, J.M.1
  • 27
    • 0033598374 scopus 로고    scopus 로고
    • Dystrophin expression in the mdx mouse restored by stem cell transplantation
    • Gussoni, E. et al. Dystrophin expression in the mdx mouse restored by stem cell transplantation. Nature 401, 390-394 (1999).
    • (1999) Nature , vol.401 , pp. 390-394
    • Gussoni, E.1
  • 28
    • 0034622814 scopus 로고    scopus 로고
    • Differential effects of dystrophin and utrophin gene transfer in immunocompetent muscular dystrophy (mdx) mice
    • Ebihara, S. et al. Differential effects of dystrophin and utrophin gene transfer in immunocompetent muscular dystrophy (mdx) mice. Physiol Genom. 3, 133-144 (2000).
    • (2000) Physiol Genom. , vol.3 , pp. 133-144
    • Ebihara, S.1
  • 29
    • 0029936764 scopus 로고    scopus 로고
    • Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors
    • Tripathy, S. K., Black, H. B., Goldwasser, E. & Leiden, J. M. Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors. Nature Med. 2, 545-550 (1996).
    • (1996) Nature Med. , vol.2 , pp. 545-550
    • Tripathy, S.K.1    Black, H.B.2    Goldwasser, E.3    Leiden, J.M.4
  • 30
    • 0036147236 scopus 로고    scopus 로고
    • Toxicity of a first-generation adenoviral vector in rhesus macaques
    • Lozier, J. N. et al. Toxicity of a first-generation adenoviral vector in rhesus macaques. Hum. Gene Ther. 13, 113-124 (2002).
    • (2002) Hum. Gene Ther. , vol.13 , pp. 113-124
    • Lozier, J.N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.