-
1
-
-
60149084560
-
MicroRNAs and cancer: Short RNAs go a long way
-
Ventura A, Jacks T. MicroRNAs and cancer: short RNAs go a long way. Cell. 2009;136(4):586-591
-
(2009)
Cell
, vol.136
, Issue.4
, pp. 586-591
-
-
Ventura, A.1
Jacks, T.2
-
2
-
-
64249092932
-
MicroRNA involvement in the pathogenesis of neuroblastoma: Potential for microRNA mediated therapeutics
-
Stallings RL. MicroRNA involvement in the pathogenesis of neuroblastoma: potential for microRNA mediated therapeutics. Curr Pharm Des. 2009;15(4):456-462.
-
(2009)
Curr Pharm des
, vol.15
, Issue.4
, pp. 456-462
-
-
Stallings, R.L.1
-
3
-
-
70349320158
-
Causes and consequences of microRNA dysregulation in cancer
-
Croce CM. Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet. 2009;10(10):704-714.
-
(2009)
Nat Rev Genet
, vol.10
, Issue.10
, pp. 704-714
-
-
Croce, C.M.1
-
4
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebert BL, Mak RH, Ferrando AA, Downing JR, Jacks T, Horvitz HR, Golub TR. MicroRNA expression profiles classify human cancers. Nature. 2005;435(7043):834-838.
-
(2005)
Nature
, vol.435
, Issue.7043
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
Sweet-Cordero, A.7
Ebert, B.L.8
Mak, R.H.9
Ferrando, A.A.10
Downing, J.R.11
Jacks, T.12
Horvitz, H.R.13
Golub, T.R.14
-
5
-
-
33144490646
-
A microRNA expression signature of human solid tumors defines cancer gene targets
-
Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F, Visone R, Iorio M, Roldo C, Ferracin M, Prueitt RL, Yanaihara N, Lanza G, Scarpa A, Vecchione A, Negrini M, Harris CC, Croce CM. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A. 2006;103(7):2257-2261.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.7
, pp. 2257-2261
-
-
Volinia, S.1
Calin, G.A.2
Liu, C.G.3
Ambs, S.4
Cimmino, A.5
Petrocca, F.6
Visone, R.7
Iorio, M.8
Roldo, C.9
Ferracin, M.10
Prueitt, R.L.11
Yanaihara, N.12
Lanza, G.13
Scarpa, A.14
Vecchione, A.15
Negrini, M.16
Harris, C.C.17
Croce, C.M.18
-
6
-
-
65649110800
-
MicroRNA expression and its implications for the diagnosis and therapeutic strategies of breast cancer
-
Shi M, Guo N. MicroRNA expression and its implications for the diagnosis and therapeutic strategies of breast cancer. Cancer Treat Rev. 2009;35(4):328-334.
-
(2009)
Cancer Treat Rev
, vol.35
, Issue.4
, pp. 328-334
-
-
Shi, M.1
Guo, N.2
-
8
-
-
36248941518
-
MicroRNAs in carcinogenesis
-
Hagan JP, Croce CM. MicroRNAs in carcinogenesis. Cytogenet Genome Res. 2007;118(2-4):252-259.
-
(2007)
Cytogenet Genome Res
, vol.118
, Issue.2-4
, pp. 252-259
-
-
Hagan, J.P.1
Croce, C.M.2
-
9
-
-
57349134379
-
Differential expression of microRNAs in early-stage neoplastic transformation in the lungs of F344 rats chronically treated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
-
Kalscheuer S, Zhang X, Zeng Y, Upadhyaya P. Differential expression of microRNAs in early-stage neoplastic transformation in the lungs of F344 rats chronically treated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone. Carcinogenesis. 2008;29(12):2394-2399.
-
(2008)
Carcinogenesis
, vol.29
, Issue.12
, pp. 2394-2399
-
-
Kalscheuer, S.1
Zhang, X.2
Zeng, Y.3
Upadhyaya, P.4
-
10
-
-
34247164636
-
Induction of microRNAome deregulation in rat liver by long-term tamoxifen exposure
-
Pogribny IP, Tryndyak VP, Boyko A, Rodriguez-Juarez R, Beland FA, Kovalchuk O. Induction of microRNAome deregulation in rat liver by long-term tamoxifen exposure. Mutat Res. 2007;619(1-2):30-37.
-
(2007)
Mutat Res
, vol.619
, Issue.1-2
, pp. 30-37
-
-
Pogribny, I.P.1
Tryndyak, V.P.2
Boyko, A.3
Rodriguez-Juarez, R.4
Beland, F.A.5
Kovalchuk, O.6
-
11
-
-
44849091255
-
Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence
-
Kumamoto K, Spillare EA, Fujita K, Horikawa I, Yamashita T, Appella E, Nagashima M, Takenoshita S, Yokota J, Harris CC. Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence. Cancer Res. 2008;68(9):3193-3203.
-
(2008)
Cancer Res
, vol.68
, Issue.9
, pp. 3193-3203
-
-
Kumamoto, K.1
Spillare, E.A.2
Fujita, K.3
Horikawa, I.4
Yamashita, T.5
Appella, E.6
Nagashima, M.7
Takenoshita, S.8
Yokota, J.9
Harris, C.C.10
-
12
-
-
65749109370
-
Down-regulation of the microRNAs miR-34a, miR-127, and miR-200b in rat liver during hepatocarcinogenesis induced by a methyl-deficient diet
-
Tryndyak VP, Ross SA, Beland FA, Pogribny IP. Down-regulation of the microRNAs miR-34a, miR-127, and miR-200b in rat liver during hepatocarcinogenesis induced by a methyl-deficient diet. Mol Carcinog. 2009;48(6):479-487.
-
(2009)
Mol Carcinog
, vol.48
, Issue.6
, pp. 479-487
-
-
Tryndyak, V.P.1
Ross, S.A.2
Beland, F.A.3
Pogribny, I.P.4
-
13
-
-
34548275102
-
Estrogeninduced rat breast carcinogenesis is characterized by alterations in DNA methylation, histone modifications and aberrant microRNA expression
-
Kovalchuk O, Tryndyak VP, Montgomery B, Boyko A, Kutanzi K, Zemp F, Warbritton AR, Latendresse JR, Kovalchuk I, Beland FA, Pogribny IP. Estrogeninduced rat breast carcinogenesis is characterized by alterations in DNA methylation, histone modifications and aberrant microRNA expression. Cell Cycle. 2007;6(16):2010-2018.
-
(2007)
Cell Cycle
, vol.6
, Issue.16
, pp. 2010-2018
-
-
Kovalchuk, O.1
Tryndyak, V.P.2
Montgomery, B.3
Boyko, A.4
Kutanzi, K.5
Zemp, F.6
Warbritton, A.R.7
Latendresse, J.R.8
Kovalchuk, I.9
Beland, F.A.10
Pogribny, I.P.11
-
14
-
-
73949158230
-
N-3 polyunsaturated fatty acids modulate carcinogen-directed non-coding microRNA signatures in rat colon
-
Davidson LA, Wang N, Shah MS, Lupton JR, Ivanov I, Chapkin RS. n-3 polyunsaturated fatty acids modulate carcinogen-directed non-coding microRNA signatures in rat colon. Carcinogenesis. 2009;30(12):2077-2084.
-
(2009)
Carcinogenesis
, vol.30
, Issue.12
, pp. 2077-2084
-
-
Davidson, L.A.1
Wang, N.2
Shah, M.S.3
Lupton, J.R.4
Ivanov, I.5
Chapkin, R.S.6
-
15
-
-
77649196575
-
Alteration of microRNA expression in vinyl-carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol
-
Melkamu T, Zhang X, Tan J, Zeng Y, Kassie F. Alteration of microRNA expression in vinyl-carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol. Carcinogenesis. 2010;31(2):252-258.
-
(2010)
Carcinogenesis
, vol.31
, Issue.2
, pp. 252-258
-
-
Melkamu, T.1
Zhang, X.2
Tan, J.3
Zeng, Y.4
Kassie, F.5
-
16
-
-
65349190811
-
MicroRNA expression profiles andmiR-10a target in anti-benzo[a] pyrene-7, 8-diol-9, 10-epoxide-transformed human 16HBE cells
-
Shen YL, Jiang YG, Greenlee AR, Zhou LL, Liu LH. MicroRNA expression profiles andmiR-10a target in anti-benzo[a] pyrene-7, 8-diol-9, 10-epoxide-transformed human 16HBE cells. Biomed Environ Sci. 2009;22(1):14-21.
-
(2009)
Biomed Environ Sci
, vol.22
, Issue.1
, pp. 14-21
-
-
Shen, Y.L.1
Jiang, Y.G.2
Greenlee, A.R.3
Zhou, L.L.4
Liu, L.H.5
-
17
-
-
66649131351
-
The expression profile of microRNAs in a model of 7,12-dimethyl-benz[a] anthrance-induced oral carcinogenesis in Syrian hamster
-
Yu T, Wang XY, Gong RG, Li A, Yang S, Cao YT, Wen YM, Wang CM, Yi XZ. The expression profile of microRNAs in a model of 7,12-dimethyl-benz[a]anthrance- induced oral carcinogenesis in Syrian hamster. J Exp Clin Cancer Res. 2009;28:64.
-
(2009)
J Exp Clin Cancer Res
, vol.28
, pp. 64
-
-
Yu, T.1
Wang, X.Y.2
Gong, R.G.3
Li, A.4
Yang, S.5
Cao, Y.T.6
Wen, Y.M.7
Wang, C.M.8
Yi, X.Z.9
-
18
-
-
0038343499
-
MicroRNA pathways in flies and worms: Growth, death, fat, stress, and timing
-
Ambros V. MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing. Cell. 2003;113(6):673-676.
-
(2003)
Cell
, vol.113
, Issue.6
, pp. 673-676
-
-
Ambros, V.1
-
19
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116(2):281-297.
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 281-297
-
-
Bartel, D.P.1
-
20
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 1993;75(5):843-854.
-
(1993)
Cell
, vol.75
, Issue.5
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
21
-
-
0034708122
-
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
-
Reinhart BJ, Slack FJ, Basson M, Pasquinelli AE, Bettinger JC, Rougvie AE, Horvitz HR, Ruvkun G. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature. 2000;403(6772):901-906.
-
(2000)
Nature
, vol.403
, Issue.6772
, pp. 901-906
-
-
Reinhart, B.J.1
Slack, F.J.2
Basson, M.3
Pasquinelli, A.E.4
Bettinger, J.C.5
Rougvie, A.E.6
Horvitz, H.R.7
Ruvkun, G.8
-
22
-
-
0037693842
-
The C elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target
-
Lin SY, Johnson SM, Abraham M, Vella MC, Pasquinelli A, Gamberi C, Gottlieb E, Slack FJ. The C elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target. Dev Cell. 2003;4(5):639-650.
-
(2003)
Dev Cell
, vol.4
, Issue.5
, pp. 639-650
-
-
Lin, S.Y.1
Johnson, S.M.2
Abraham, M.3
Vella, M.C.4
Pasquinelli, A.5
Gamberi, C.6
Gottlieb, E.7
Slack, F.J.8
-
23
-
-
0038708326
-
The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs
-
Abrahante JE, Daul AL, Li M, Volk ML, Tennessen JM, Miller EA, Rougvie AE. The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. Dev Cell. 2003;4(5):625-637.
-
(2003)
Dev Cell
, vol.4
, Issue.5
, pp. 625-637
-
-
Abrahante, J.E.1
Daul, A.L.2
Li, M.3
Volk, M.L.4
Tennessen, J.M.5
Miller, E.A.6
Rougvie, A.E.7
-
24
-
-
0033634943
-
The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
-
Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol Cell. 2000;5(4):659-669.
-
(2000)
Mol Cell
, vol.5
, Issue.4
, pp. 659-669
-
-
Slack, F.J.1
Basson, M.2
Liu, Z.3
Ambros, V.4
Horvitz, H.R.5
Ruvkun, G.6
-
25
-
-
0942301280
-
The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR
-
Vella MC, Choi EY, Lin SY, Reinert K, Slack FJ. The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR. Genes Dev. 2004;18(2):132-137.
-
(2004)
Genes Dev
, vol.18
, Issue.2
, pp. 132-137
-
-
Vella, M.C.1
Choi, E.Y.2
Lin, S.Y.3
Reinert, K.4
Slack, F.J.5
-
26
-
-
33845242919
-
MicroRNAs: Regulators of gene expression and cell differentiation
-
Shivdasani RA. MicroRNAs: regulators of gene expression and cell differentiation. Blood. 2006;108(12):3646-3653.
-
(2006)
Blood
, vol.108
, Issue.12
, pp. 3646-3653
-
-
Shivdasani, R.A.1
-
27
-
-
0242361521
-
Regulation of flowering time and floral organ identity by a MicroRNA and its APETALA2-like target genes
-
Aukerman MJ, Sakai H. Regulation of flowering time and floral organ identity by a MicroRNA and its APETALA2-like target genes. Plant Cell. 2003;15(11):2730-2741.
-
(2003)
Plant Cell
, vol.15
, Issue.11
, pp. 2730-2741
-
-
Aukerman, M.J.1
Sakai, H.2
-
28
-
-
0347357618
-
A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans
-
Johnston RJ, Hobert O. A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans. Nature. 2003;426(6968):845-849.
-
(2003)
Nature
, vol.426
, Issue.6968
, pp. 845-849
-
-
Johnston, R.J.1
Hobert, O.2
-
29
-
-
68949190853
-
MicroRNAs involved in tumor suppressor and oncogene pathways: Implications for hepatobiliary neoplasia
-
Mott JL. MicroRNAs involved in tumor suppressor and oncogene pathways: implications for hepatobiliary neoplasia. Hepatology. 2009;50(2):630-637.
-
(2009)
Hepatology
, vol.50
, Issue.2
, pp. 630-637
-
-
Mott, J.L.1
-
30
-
-
33749519036
-
Implications of micro-RNA profiling for cancer diagnosis
-
Cummins JM, Velculescu VE. Implications of micro-RNA profiling for cancer diagnosis. Oncogene. 2006;25(46):6220-6227.
-
(2006)
Oncogene
, vol.25
, Issue.46
, pp. 6220-6227
-
-
Cummins, J.M.1
Velculescu, V.E.2
-
31
-
-
0035955361
-
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
-
Lau NC, Lim LP,Weinstein EG, Bartel DP. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science. 2001;294(5543):858-862.
-
(2001)
Science
, vol.294
, Issue.5543
, pp. 858-862
-
-
Lau, N.C.1
Lim Lpweinstein, E.G.2
Bartel, D.P.3
-
32
-
-
0035955374
-
Identification of novel genes coding for small expressed RNAs
-
Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T. Identification of novel genes coding for small expressed RNAs. Science. 2001;294(5543):853-858.
-
(2001)
Science
, vol.294
, Issue.5543
, pp. 853-858
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Lendeckel, W.3
Tuschl, T.4
-
33
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
Lee Y, Kim M, Han J, Yeom KH, Lee S, Baek SH, Kim VN. MicroRNA genes are transcribed by RNA polymerase II. Embo J. 2004;23(20):4051-4060.
-
(2004)
Embo J
, vol.23
, Issue.20
, pp. 4051-4060
-
-
Lee, Y.1
Kim, M.2
Han, J.3
Yeom, K.H.4
Lee, S.5
Baek, S.H.6
Kim, V.N.7
-
34
-
-
9344235449
-
Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
-
Cai X, Hagedorn CH, Cullen BR. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA. 2004;10(12):1957-1966.
-
(2004)
RNA
, vol.10
, Issue.12
, pp. 1957-1966
-
-
Cai, X.1
Hagedorn, C.H.2
Cullen, B.R.3
-
35
-
-
10644234841
-
The Drosha-DGCR8 complex in primary microRNA processing
-
Han J, Lee Y, Yeom KH, Kim YK, Jin H, Kim VN. The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev. 2004;18(24):3016-3027.
-
(2004)
Genes Dev
, vol.18
, Issue.24
, pp. 3016-3027
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
Kim, Y.K.4
Jin, H.5
Kim, V.N.6
-
36
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J, Lee J, Provost P, Radmark O, Kim S, Kim VN. The nuclear RNase III Drosha initiates microRNA processing. Nature. 2003;425(6956):415-419.
-
(2003)
Nature
, vol.425
, Issue.6956
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Radmark, O.9
Kim, S.10
Kim, V.N.11
-
37
-
-
33744520104
-
Molecular basis for the recognition of primary microRNAs by the Drosha- DGCR8 complex
-
Han J, Lee Y, Yeom KH, Nam JW, Heo I, Rhee JK, Sohn SY, Cho Y, Zhang BT, Kim VN. Molecular basis for the recognition of primary microRNAs by the Drosha- DGCR8 complex. Cell. 2006;125(5):887-901.
-
(2006)
Cell
, vol.125
, Issue.5
, pp. 887-901
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
Nam, J.W.4
Heo, I.5
Rhee, J.K.6
Sohn, S.Y.7
Cho, Y.8
Zhang, B.T.9
Kim, V.N.10
-
38
-
-
0037009364
-
MicroRNA maturation: Stepwise processing and subcellular localization
-
Lee Y, Jeon K, Lee JT, Kim S, Kim VN. MicroRNA maturation: stepwise processing and subcellular localization. Embo J. 2002;21(17):4663-4670.
-
(2002)
Embo J
, vol.21
, Issue.17
, pp. 4663-4670
-
-
Lee, Y.1
Jeon, K.2
Lee, J.T.3
Kim, S.4
Kim, V.N.5
-
39
-
-
1842608548
-
MicroRNA precursors in motion: Exportin-5 mediates their nuclear export
-
Kim VN. MicroRNA precursors in motion: exportin-5 mediates their nuclear export. Trends Cell Biol. 2004;14(4):156-159.
-
(2004)
Trends Cell Biol
, vol.14
, Issue.4
, pp. 156-159
-
-
Kim, V.N.1
-
40
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund E, Guttinger S, Calado A, Dahlberg JE, Kutay U. Nuclear export of microRNA precursors. Science. 2004;303(5654):95-98.
-
(2004)
Science
, vol.303
, Issue.5654
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
41
-
-
1642499415
-
Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
-
Bohnsack MT, Czaplinski K, Gorlich D. Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA. 2004;10(2):185-191.
-
(2004)
RNA
, vol.10
, Issue.2
, pp. 185-191
-
-
Bohnsack, M.T.1
Czaplinski, K.2
Gorlich, D.3
-
42
-
-
34250677322
-
Substrate selectivity of exportin 5 and Dicer in the biogenesis of microRNAs
-
Lund E, Dahlberg JE. Substrate selectivity of exportin 5 and Dicer in the biogenesis of microRNAs. Cold Spring Harb Symp Quant Biol. 2006;71:59-66.
-
(2006)
Cold Spring Harb Symp Quant Biol
, vol.71
, pp. 59-66
-
-
Lund, E.1
Dahlberg, J.E.2
-
43
-
-
29144431656
-
A human, ATP-independent, RISC assembly machine fueled by pre-miRNA
-
Maniataki E, Mourelatos Z. A human, ATP-independent, RISC assembly machine fueled by pre-miRNA. Genes Dev. 2005;19(24):2979-2990.
-
(2005)
Genes Dev
, vol.19
, Issue.24
, pp. 2979-2990
-
-
Maniataki, E.1
Mourelatos, Z.2
-
44
-
-
27744537851
-
Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
-
Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R. Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell. 2005;123(4):631-640.
-
(2005)
Cell
, vol.123
, Issue.4
, pp. 631-640
-
-
Gregory, R.I.1
Chendrimada, T.P.2
Cooch, N.3
Shiekhattar, R.4
-
45
-
-
20444436381
-
Cancer genomics: Small RNAs with big impacts
-
Meltzer PS. Cancer genomics: small RNAs with big impacts. Nature. 2005;435(7043):745-746.
-
(2005)
Nature
, vol.435
, Issue.7043
, pp. 745-746
-
-
Meltzer, P.S.1
-
46
-
-
2142654329
-
MicroRNA-directed cleavage of HOXB8 mRNA
-
Yekta S, Shih IH, Bartel DP. MicroRNA-directed cleavage of HOXB8 mRNA. Science. 2004;304(5670):594-596.
-
(2004)
Science
, vol.304
, Issue.5670
, pp. 594-596
-
-
Yekta, S.1
Shih, I.H.2
Bartel, D.P.3
-
47
-
-
0037144546
-
A microRNA in a multiple-turnover RNAi enzyme complex
-
Hutvagner G, Zamore PD. A microRNA in a multiple-turnover RNAi enzyme complex. Science. 2002;297(5589):2056-2060.
-
(2002)
Science
, vol.297
, Issue.5589
, pp. 2056-2060
-
-
Hutvagner, G.1
Zamore, P.D.2
-
48
-
-
4644223259
-
Mechanisms of gene silencing by double-stranded RNA
-
Meister G, Tuschl T. Mechanisms of gene silencing by double-stranded RNA. Nature. 2004;431(7006):343-349.
-
(2004)
Nature
, vol.431
, Issue.7006
, pp. 343-349
-
-
Meister, G.1
Tuschl, T.2
-
50
-
-
34547441263
-
Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR
-
Lytle JR, Yario TA, Steitz JA. Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR. Proc Natl Acad Sci U S A. 2007;104(23):9667-9672.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.23
, pp. 9667-9672
-
-
Lytle, J.R.1
Yario, T.A.2
Steitz, J.A.3
-
51
-
-
42449086421
-
MiR-148 targets human DNMT3b protein coding region
-
Duursma AM, Kedde M, Schrier M, le Sage C, Agami R. miR-148 targets human DNMT3b protein coding region. RNA. 2008;14(5):872-877.
-
(2008)
RNA
, vol.14
, Issue.5
, pp. 872-877
-
-
Duursma, A.M.1
Kedde, M.2
Schrier, M.3
Le Sage, C.4
Agami, R.5
-
52
-
-
54549108798
-
MicroRNAs to Nanog Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation
-
Tay Y, Zhang J, Thomson AM, Lim B, Rigoutsos I. MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature. 2008;455(7216):1124-1128.
-
(2008)
Nature
, vol.455
, Issue.7216
, pp. 1124-1128
-
-
Tay, Y.1
Zhang, J.2
Thomson, A.M.3
Lim, B.4
Rigoutsos, I.5
-
53
-
-
0346094457
-
Prediction of mammalian microRNA targets
-
Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell. 2003;115(7):787-798.
-
(2003)
Cell
, vol.115
, Issue.7
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
Bartel, D.P.4
Burge, C.B.5
-
54
-
-
28044457883
-
MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function
-
Humphreys DT, Westman BJ, Martin DI, Preiss T. MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function. Proc Natl Acad Sci U S A. 2005;102(47):16961-16966.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.47
, pp. 16961-16966
-
-
Humphreys, D.T.1
Westman, B.J.2
Martin, D.I.3
Preiss, T.4
-
55
-
-
32444436121
-
Short RNAs repress translation after initiation in mammalian cells
-
Petersen CP, Bordeleau ME, Pelletier J, Sharp PA. Short RNAs repress translation after initiation in mammalian cells. Mol Cell. 2006;21(4):533-542.
-
(2006)
Mol Cell
, vol.21
, Issue.4
, pp. 533-542
-
-
Petersen, C.P.1
Bordeleau, M.E.2
Pelletier, J.3
Sharp, P.A.4
-
56
-
-
33645119514
-
MicroRNAs direct rapid deadenylation of mRNA
-
Wu L, Fan J, Belasco JG. MicroRNAs direct rapid deadenylation of mRNA. Proc Natl Acad Sci U S A. 2006;103(11):4034-4039.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.11
, pp. 4034-4039
-
-
Wu, L.1
Fan, J.2
Belasco, J.G.3
-
57
-
-
58849093262
-
Revisiting the principles of microRNA target recognition and mode of action
-
Brodersen P, Voinnet O. Revisiting the principles of microRNA target recognition and mode of action. Nat Rev Mol Cell Biol. 2009;10(2):141-148.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, Issue.2
, pp. 141-148
-
-
Brodersen, P.1
Voinnet, O.2
-
59
-
-
33748928159
-
The diverse functions of microRNAs in animal development and disease
-
Kloosterman WP, Plasterk RH. The diverse functions of microRNAs in animal development and disease. Dev Cell. 2006;11(4):441-450.
-
(2006)
Dev Cell
, vol.11
, Issue.4
, pp. 441-450
-
-
Kloosterman, W.P.1
Plasterk, R.H.2
-
60
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 2005;120(1):15-20.
-
(2005)
Cell
, vol.120
, Issue.1
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
61
-
-
13944282215
-
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
-
Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, Bartel DP, Linsley PS, Johnson JM. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature. 2005;433(7027):769-773.
-
(2005)
Nature
, vol.433
, Issue.7027
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
Grimson, A.4
Schelter, J.M.5
Castle, J.6
Bartel, D.P.7
Linsley, P.S.8
Johnson, J.M.9
-
62
-
-
0037418839
-
Bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila
-
Brennecke J, Hipfner DR, Stark A, Russell RB, Cohen SM. bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell. 2003;113(1):25-36.
-
(2003)
Cell
, vol.113
, Issue.1
, pp. 25-36
-
-
Brennecke, J.1
Hipfner, D.R.2
Stark, A.3
Russell, R.B.4
Cohen, S.M.5
-
63
-
-
0037694970
-
The Drosophila microRNA Mir-14 suppresses cell death and is required for normal fat metabolism
-
Xu P, Vernooy SY, Guo M, Hay BA. The Drosophila microRNA Mir-14 suppresses cell death and is required for normal fat metabolism. Curr Biol. 2003;13(9):790-795.
-
(2003)
Curr Biol
, vol.13
, Issue.9
, pp. 790-795
-
-
Xu, P.1
Vernooy, S.Y.2
Guo, M.3
Hay, B.A.4
-
65
-
-
0027730383
-
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
-
Wightman B, Ha I, Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell. 1993;75(5):855-862.
-
(1993)
Cell
, vol.75
, Issue.5
, pp. 855-862
-
-
Wightman, B.1
Ha, I.2
Ruvkun, G.3
-
66
-
-
0030970775
-
The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA
-
Moss EG, Lee RC, Ambros V. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell. 1997;88(5):637-646.
-
(1997)
Cell
, vol.88
, Issue.5
, pp. 637-646
-
-
Moss, E.G.1
Lee, R.C.2
Ambros, V.3
-
67
-
-
0036544755
-
Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation
-
Lai EC. Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation. Nat Genet. 2002;30(4):363-364.
-
(2002)
Nat Genet
, vol.30
, Issue.4
, pp. 363-364
-
-
Lai, E.C.1
-
68
-
-
76649105418
-
MicroRNA function in cancer: Oncogene or a tumor suppressor?
-
Shenouda SK, Alahari SK. MicroRNA function in cancer: oncogene or a tumor suppressor? Cancer Metastasis Rev. 2009;28(3-4):369-378.
-
(2009)
Cancer Metastasis Rev
, vol.28
, Issue.3-4
, pp. 369-378
-
-
Shenouda, S.K.1
Alahari, S.K.2
-
69
-
-
66049130038
-
MicroRNAs and cancer-new paradigms in molecular oncology
-
Negrini M, Nicoloso MS, Calin GA. MicroRNAs and cancer-new paradigms in molecular oncology. Curr Opin Cell Biol. 2009;21(3):470-479.
-
(2009)
Curr Opin Cell Biol
, vol.21
, Issue.3
, pp. 470-479
-
-
Negrini, M.1
Nicoloso, M.S.2
Calin, G.A.3
-
71
-
-
73349125465
-
MicroRNAs in cancer: Small molecules with a huge impact
-
Iorio MV, Croce CM. MicroRNAs in cancer: small molecules with a huge impact. J Clin Oncol. 2009;27(34):5848-5856.
-
(2009)
J Clin Oncol
, vol.27
, Issue.34
, pp. 5848-5856
-
-
Iorio, M.V.1
Croce, C.M.2
-
74
-
-
58649089534
-
Oncomirs: The potential role of non-coding microRNAs in understanding cancer
-
Manikandan J, Aarthi JJ, Kumar SD, Pushparaj PN. Oncomirs: The potential role of non-coding microRNAs in understanding cancer. Bioinformation. 2008;2(8):330-334.
-
(2008)
Bioinformation
, vol.2
, Issue.8
, pp. 330-334
-
-
Manikandan, J.1
Aarthi, J.J.2
Kumar, S.D.3
Pushparaj, P.N.4
-
75
-
-
34249817549
-
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
-
Chang TC, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, Lee KH, Feldmann G, Yamakuchi M, Ferlito M, Lowenstein CJ, Arking DE, Beer MA, Maitra A, Mendell JT. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell. 2007;26(5):745-752.
-
(2007)
Mol Cell
, vol.26
, Issue.5
, pp. 745-752
-
-
Chang, T.C.1
Wentzel, E.A.2
Kent, O.A.3
Ramachandran, K.4
Mullendore, M.5
Lee, K.H.6
Feldmann, G.7
Yamakuchi, M.8
Ferlito, M.9
Lowenstein, C.J.10
Arking, D.E.11
Beer, M.A.12
Maitra, A.13
Mendell, J.T.14
-
76
-
-
49749150980
-
A Functional Screen Identifies miR-34a as a Candidate Neuroblastoma Tumor Suppressor Gene
-
Cole KA, Attiyeh EF, Mosse YP, Laquaglia MJ, Diskin SJ, Brodeur GM, Maris JM. A Functional Screen Identifies miR-34a as a Candidate Neuroblastoma Tumor Suppressor Gene. Mol Cancer Res. 2008;6(5):735-742.
-
(2008)
Mol Cancer Res
, vol.6
, Issue.5
, pp. 735-742
-
-
Cole, K.A.1
Attiyeh, E.F.2
Mosse, Y.P.3
Laquaglia, M.J.4
Diskin, S.J.5
Brodeur, G.M.6
Maris, J.M.7
-
77
-
-
34250868124
-
Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: Mir-34a is a p53 target that induces apoptosis and G1-arrest
-
Tarasov V, Jung P, Verdoodt B, Lodygin D, Epanchintsev A, Menssen A, Meister G, Hermeking H. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle. 2007;6(13):1586-1593.
-
(2007)
Cell Cycle
, vol.6
, Issue.13
, pp. 1586-1593
-
-
Tarasov, V.1
Jung, P.2
Verdoodt, B.3
Lodygin, D.4
Epanchintsev, A.5
Menssen, A.6
Meister, G.7
Hermeking, H.8
-
78
-
-
34249822779
-
Transcriptional activation ofmiR-34a contributes to p53-mediated apoptosis
-
Raver-Shapira N, Marciano E, Meiri E, Spector Y, Rosenfeld N, Moskovits N, Bentwich Z, Oren M. Transcriptional activation ofmiR-34a contributes to p53-mediated apoptosis. Mol Cell. 2007;26(5):731-743.
-
(2007)
Mol Cell
, vol.26
, Issue.5
, pp. 731-743
-
-
Raver-Shapira, N.1
Marciano, E.2
Meiri, E.3
Spector, Y.4
Rosenfeld, N.5
Moskovits, N.6
Bentwich, Z.7
Oren, M.8
-
79
-
-
73649129263
-
Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumours
-
Subramanian S, Thayanithy V, West RB, Lee CH, Beck AH, Zhu S, Downs-Kelly E, Montgomery K, Goldblum JR, Hogendoorn PC, Corless CL, Oliveira AM, Dry SM, Nielsen TO, Rubin BP, Fletcher JA, Fletcher CD, van de Rijn M. Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumours. J Pathol. 2010;220(1):58-70.
-
(2010)
J Pathol
, vol.220
, Issue.1
, pp. 58-70
-
-
Subramanian, S.1
Thayanithy, V.2
West, R.B.3
Lee, C.H.4
Beck, A.H.5
Zhu, S.6
Downs-Kelly, E.7
Montgomery, K.8
Goldblum, J.R.9
Hogendoorn, P.C.10
Corless, C.L.11
Oliveira, A.M.12
Dry, S.M.13
Nielsen, T.O.14
Rubin, B.P.15
Fletcher, J.A.16
Fletcher, C.D.17
Van De Rijn, M.18
-
81
-
-
34249812122
-
MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells
-
Welch C, Chen Y, Stallings RL. MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. Oncogene. 2007;26(34):5017-5022.
-
(2007)
Oncogene
, vol.26
, Issue.34
, pp. 5017-5022
-
-
Welch, C.1
Chen, Y.2
Stallings, R.L.3
-
82
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y, Xue W, Zender L, Magnus J, Ridzon D, Jackson AL, Linsley PS, Chen C, Lowe SW, Cleary MA, Hannon GJ. A microRNA component of the p53 tumour suppressor network. Nature. 2007;447(7148):1130-1134.
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
De Stanchina, E.4
Xuan, Z.5
Liang, Y.6
Xue, W.7
Zender, L.8
Magnus, J.9
Ridzon, D.10
Jackson, A.L.11
Linsley, P.S.12
Chen, C.13
Lowe, S.W.14
Cleary, M.A.15
Hannon, G.J.16
-
83
-
-
34848868157
-
Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
-
Tazawa H, Tsuchiya N, Izumiya M, Nakagama H. Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc Natl Acad Sci U S A. 2007;104(39):15472-15477.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.39
, pp. 15472-15477
-
-
Tazawa, H.1
Tsuchiya, N.2
Izumiya, M.3
Nakagama, H.4
-
84
-
-
35748961986
-
P53 enters the microRNA world
-
Hermeking H. p53 enters the microRNA world. Cancer Cell. 2007;12(5):414-418.
-
(2007)
Cancer Cell
, vol.12
, Issue.5
, pp. 414-418
-
-
Hermeking, H.1
-
85
-
-
37049010980
-
The guardian's little helper: Micrornas in the p53 tumor suppressor network
-
He X, He L, Hannon GJ. The guardian's little helper: microRNAs in the p53 tumor suppressor network. Cancer Res. 2007;67(23):11099-11101.
-
(2007)
Cancer Res
, vol.67
, Issue.23
, pp. 11099-11101
-
-
He, X.1
He, L.2
Hannon, G.J.3
-
86
-
-
42049092138
-
Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest
-
Sun F, Fu H, Liu Q, Tie Y, Zhu J, Xing R, Sun Z, Zheng X. Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest. FEBS Lett. 2008;582(10):1564-1568.
-
(2008)
FEBS Lett
, vol.582
, Issue.10
, pp. 1564-1568
-
-
Sun, F.1
Fu, H.2
Liu, Q.3
Tie, Y.4
Zhu, J.5
Xing, R.6
Sun, Z.7
Zheng, X.8
-
87
-
-
49749151009
-
MicroRNA-34 mediates AR-dependent p53-induced apoptosis in prostate cancer
-
Rokhlin OW, Scheinker VS, Taghiyev AF, Bumcrot D, Glover RA, Cohen MB. MicroRNA-34 mediates AR-dependent p53-induced apoptosis in prostate cancer. Cancer Biol Ther. 2008;7(8):1288-1296.
-
(2008)
Cancer Biol Ther
, vol.7
, Issue.8
, pp. 1288-1296
-
-
Rokhlin, O.W.1
Scheinker, V.S.2
Taghiyev, A.F.3
Bumcrot, D.4
Glover, R.A.5
Cohen, M.B.6
-
88
-
-
51349157982
-
The MYCN oncogene is a direct target of miR-34a
-
Wei JS, Song YK, Durinck S, Chen QR, Cheuk AT, Tsang P, Zhang Q, Thiele CJ, Slack A, Shohet J, Khan J. The MYCN oncogene is a direct target of miR-34a. Oncogene. 2008;27(39):5204-5213.
-
(2008)
Oncogene
, vol.27
, Issue.39
, pp. 5204-5213
-
-
Wei, J.S.1
Song, Y.K.2
Durinck, S.3
Chen, Q.R.4
Cheuk, A.T.5
Tsang, P.6
Zhang, Q.7
Thiele, C.J.8
Slack, A.9
Shohet, J.10
Khan, J.11
-
89
-
-
47549109566
-
MicroRNA- 21 promotes cell transformation by targeting the programmed cell death 4 gene
-
Lu Z, LiuM, Stribinskis V, Klinge CM, Ramos KS, Colburn NH, Li Y. MicroRNA- 21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene. 2008;27(31):4373-4379.
-
(2008)
Oncogene
, vol.27
, Issue.31
, pp. 4373-4379
-
-
Lu, Z.1
Lium Stribinskis, V.2
Klinge, C.M.3
Ramos, K.S.4
Colburn, N.H.5
Li, Y.6
-
90
-
-
40249092910
-
MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
-
Zhu S, Wu H, Wu F, Nie D, Sheng S, Mo YY. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res. 2008;18(3):350-359.
-
(2008)
Cell Res
, vol.18
, Issue.3
, pp. 350-359
-
-
Zhu, S.1
Wu, H.2
Wu, F.3
Nie, D.4
Sheng, S.5
Mo, Y.Y.6
-
91
-
-
41749113108
-
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
-
Asangani IA, Rasheed SA, Nikolova DA, Leupold JH, Colburn NH, Post S, Allgayer H. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene. 2008;27(15):2128-2136.
-
(2008)
Oncogene
, vol.27
, Issue.15
, pp. 2128-2136
-
-
Asangani, I.A.1
Rasheed, S.A.2
Nikolova, D.A.3
Leupold, J.H.4
Colburn, N.H.5
Post, S.6
Allgayer, H.7
-
92
-
-
35148900227
-
MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas
-
Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah K. MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. Cancer Res. 2007;67(19):8994-9000.
-
(2007)
Cancer Res
, vol.67
, Issue.19
, pp. 8994-9000
-
-
Corsten, M.F.1
Miranda, R.2
Kasmieh, R.3
Krichevsky, A.M.4
Weissleder, R.5
Shah, K.6
-
93
-
-
34347266556
-
MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
-
Zhu S, Si ML, Wu H, Mo YY. MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J Biol Chem. 2007;282(19):14328-14336.
-
(2007)
J Biol Chem
, vol.282
, Issue.19
, pp. 14328-14336
-
-
Zhu, S.1
Si, M.L.2
Wu, H.3
Mo, Y.Y.4
-
94
-
-
34247495591
-
MiR-21-mediated tumor growth
-
Si ML, Zhu S, Wu H, Lu Z, Wu F, Mo YY. miR-21-mediated tumor growth. Oncogene. 2007;26(19):2799-2803.
-
(2007)
Oncogene
, vol.26
, Issue.19
, pp. 2799-2803
-
-
Si, M.L.1
Zhu, S.2
Wu, H.3
Lu, Z.4
Wu, F.5
Mo, Y.Y.6
-
95
-
-
22244467087
-
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
-
Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res. 2005;65(14):6029-6033.
-
(2005)
Cancer Res
, vol.65
, Issue.14
, pp. 6029-6033
-
-
Chan, J.A.1
Krichevsky, A.M.2
Kosik, K.S.3
-
96
-
-
70349256065
-
MiR-34a contributes to megakaryocytic differentiation of K562 cells independently of p53
-
Navarro F, Gutman D, Meire E, Caceres M, Rigoutsos I, Bentwich Z, Lieberman J. miR-34a contributes to megakaryocytic differentiation of K562 cells independently of p53. Blood. 2009;114(10):2181-2192.
-
(2009)
Blood
, vol.114
, Issue.10
, pp. 2181-2192
-
-
Navarro, F.1
Gutman, D.2
Meire, E.3
Caceres, M.4
Rigoutsos, I.5
Bentwich, Z.6
Lieberman, J.7
-
97
-
-
27244432205
-
MicroRNAs as oncogenes and tumor suppressors
-
Chen CZ. MicroRNAs as oncogenes and tumor suppressors. N Engl J Med. 2005;353(17):1768-1771.
-
(2005)
N Engl J Med
, vol.353
, Issue.17
, pp. 1768-1771
-
-
Chen, C.Z.1
-
98
-
-
25444520537
-
MiR-15 and miR-16 induce apoptosis by targeting BCL2
-
Cimmino A, Calin GA, Fabbri M, Iorio MV, Ferracin M, Shimizu M, Wojcik SE, Aqeilan RI, Zupo S, Dono M, Rassenti L, Alder H, Volinia S, Liu CG, Kipps TJ, Negrini M, Croce CM. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci U S A. 2005;102(39):13944-13949.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.39
, pp. 13944-13949
-
-
Cimmino, A.1
Calin, G.A.2
Fabbri, M.3
Iorio, M.V.4
Ferracin, M.5
Shimizu, M.6
Wojcik, S.E.7
Aqeilan, R.I.8
Zupo, S.9
Dono, M.10
Rassenti, L.11
Alder, H.12
Volinia, S.13
Liu, C.G.14
Kipps, T.J.15
Negrini, M.16
Croce, C.M.17
-
99
-
-
0031917523
-
Does tamoxifen cause cancer in humans?
-
Stearns V, Gelmann EP. Does tamoxifen cause cancer in humans? J Clin Oncol. 1998;16(2):779-792.
-
(1998)
J Clin Oncol
, vol.16
, Issue.2
, pp. 779-792
-
-
Stearns, V.1
Gelmann, E.P.2
-
101
-
-
0027308685
-
The triphenylethylene drug tamoxifen is a strong liver carcinogen in the rat
-
Williams GM, Iatropoulos MJ, Djordjevic MV, Kaltenberg OP. The triphenylethylene drug tamoxifen is a strong liver carcinogen in the rat. Carcinogenesis. 1993;14(2):315-317.
-
(1993)
Carcinogenesis
, vol.14
, Issue.2
, pp. 315-317
-
-
Williams, G.M.1
Iatropoulos, M.J.2
Djordjevic, M.V.3
Kaltenberg, O.P.4
-
102
-
-
0030050137
-
Identification of the major tamoxifen-deoxyguanosine adduct formed in the liver DNA of rats treated with tamoxifen
-
Osborne MR, Hewer A, Hardcastle IR, Carmichael PL, Phillips DH. Identification of the major tamoxifen-deoxyguanosine adduct formed in the liver DNA of rats treated with tamoxifen. Cancer Res. 1996;56(1):66-71.
-
(1996)
Cancer Res
, vol.56
, Issue.1
, pp. 66-71
-
-
Osborne, M.R.1
Hewer, A.2
Hardcastle, I.R.3
Carmichael, P.L.4
Phillips, D.H.5
-
103
-
-
0037039714
-
Induction of lacI mutations in Big Blue rats treated with tamoxifen and alpha-hydroxytamoxifen
-
da Costa GG, Manjanatha MG, Marques MM, Beland FA. Induction of lacI mutations in Big Blue rats treated with tamoxifen and alpha-hydroxytamoxifen. Cancer Lett. 2002;176(1):37-45.
-
(2002)
Cancer Lett
, vol.176
, Issue.1
, pp. 37-45
-
-
Da Costa, G.G.1
Manjanatha, M.G.2
Marques, M.M.3
Beland, F.A.4
-
104
-
-
0030999951
-
Tamoxifen causes gene mutations in the livers of lambda/lacI transgenic rats
-
Davies R, Oreffo VI, Martin EA, Festing MF, White IN, Smith LL, Styles JA. Tamoxifen causes gene mutations in the livers of lambda/lacI transgenic rats. Cancer Res. 1997;57(7):1288-1293.
-
(1997)
Cancer Res
, vol.57
, Issue.7
, pp. 1288-1293
-
-
Davies, R.1
Oreffo, V.I.2
Martin, E.A.3
Festing, M.F.4
White, I.N.5
Smith, L.L.6
Styles, J.A.7
-
105
-
-
60749094708
-
The tumor-promoting activity of 2-acetylaminofluorene is associated with disruption of the p53 signaling pathway and the balance between apoptosis and cell proliferation
-
Pogribny IP, Muskhelishvili L, Tryndyak VP, Beland FA. The tumor-promoting activity of 2-acetylaminofluorene is associated with disruption of the p53 signaling pathway and the balance between apoptosis and cell proliferation. Toxicol Appl Pharmacol. 2009;235(3):305-311.
-
(2009)
Toxicol Appl Pharmacol
, vol.235
, Issue.3
, pp. 305-311
-
-
Pogribny, I.P.1
Muskhelishvili, L.2
Tryndyak, V.P.3
Beland, F.A.4
-
106
-
-
13944282327
-
Cytochrome P450 enzymes as catalysts of metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco specific carcinogen
-
Jalas JR, Hecht SS, Murphy SE. Cytochrome P450 enzymes as catalysts of metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco specific carcinogen. Chem Res Toxicol. 2005;18(2):95-110.
-
(2005)
Chem Res Toxicol
, vol.18
, Issue.2
, pp. 95-110
-
-
Jalas, J.R.1
Hecht, S.S.2
Murphy, S.E.3
-
107
-
-
0034063909
-
Radiation carcinogenesis
-
Little JB. Radiation carcinogenesis. Carcinogenesis. 2000;21(3):397-404.
-
(2000)
Carcinogenesis
, vol.21
, Issue.3
, pp. 397-404
-
-
Little, J.B.1
-
108
-
-
54449092059
-
Altered microRNA expression patterns in irradiated hematopoietic tissues suggest a sex-specific protective mechanism
-
Ilnytskyy Y, Zemp FJ, Koturbash I, Kovalchuk O. Altered microRNA expression patterns in irradiated hematopoietic tissues suggest a sex-specific protective mechanism. Biochem Biophys Res Commun. 2008;377(1):41-45.
-
(2008)
Biochem Biophys Res Commun
, vol.377
, Issue.1
, pp. 41-45
-
-
Ilnytskyy, Y.1
Zemp, F.J.2
Koturbash, I.3
Kovalchuk, O.4
-
109
-
-
4644250896
-
Lsh, an epigenetic guardian of repetitive elements
-
Huang J, Fan T, Yan Q, Zhu H, Fox S, Issaq HJ, Best L, Gangi L, Munroe D, Muegge K. Lsh, an epigenetic guardian of repetitive elements. Nucleic Acids Res. 2004;32(17):5019-5028.
-
(2004)
Nucleic Acids Res
, vol.32
, Issue.17
, pp. 5019-5028
-
-
Huang, J.1
Fan, T.2
Yan, Q.3
Zhu, H.4
Fox, S.5
Issaq, H.J.6
Best, L.7
Gangi, L.8
Munroe, D.9
Muegge, K.10
-
110
-
-
7444226882
-
Sex- and tissue-specific expression of maintenance and de novo DNA methyltransferases upon low dose Xirradiation in mice
-
Raiche J, Rodriguez-Juarez R, Pogribny I, Kovalchuk O. Sex- and tissue-specific expression of maintenance and de novo DNA methyltransferases upon low dose Xirradiation in mice. Biochem Biophys Res Commun. 2004;325(1):39-47.
-
(2004)
Biochem Biophys Res Commun
, vol.325
, Issue.1
, pp. 39-47
-
-
Raiche, J.1
Rodriguez-Juarez, R.2
Pogribny, I.3
Kovalchuk, O.4
-
111
-
-
34548177451
-
Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells
-
Lukiw WJ, Pogue AI. Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells. J Inorg Biochem. 2007;101(9):1265-1269.
-
(2007)
J Inorg Biochem
, vol.101
, Issue.9
, pp. 1265-1269
-
-
Lukiw, W.J.1
Pogue, A.I.2
-
112
-
-
65249115670
-
Involvement of MicroRNAs in hydrogen peroxide-mediated gene regulation and cellular injury response in vascular smooth muscle cells
-
Lin Y, Liu X, Cheng Y, Yang J, Huo Y, Zhang C. Involvement of MicroRNAs in hydrogen peroxide-mediated gene regulation and cellular injury response in vascular smooth muscle cells. J Biol Chem. 2009;284(12):7903-7913.
-
(2009)
J Biol Chem
, vol.284
, Issue.12
, pp. 7903-7913
-
-
Lin, Y.1
Liu, X.2
Cheng, Y.3
Yang, J.4
Huo, Y.5
Zhang, C.6
-
113
-
-
67349106068
-
MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4
-
Cheng Y, Liu X, Zhang S, Lin Y, Yang J, Zhang C. MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4. J Mol Cell Cardiol. 2009;47(1):5-14.
-
(2009)
J Mol Cell Cardiol
, vol.47
, Issue.1
, pp. 5-14
-
-
Cheng, Y.1
Liu, X.2
Zhang, S.3
Lin, Y.4
Yang, J.5
Zhang, C.6
-
114
-
-
77951655547
-
A potential microRNA signature for tumorigenic conazoles in mouse liver
-
Ross J, Blackman C, Thai S, Li Z, Kohan M, Jones C, Chen T. A potential microRNA signature for tumorigenic conazoles in mouse liver. Molecular Carcinogenesis. 2010;49(4):320-323.
-
(2010)
Molecular Carcinogenesis
, vol.49
, Issue.4
, pp. 320-323
-
-
Ross, J.1
Blackman, C.2
Thai, S.3
Li, Z.4
Kohan, M.5
Jones, C.6
Chen, T.7
-
115
-
-
38449116456
-
MicroRNAs in adult rodent liver are refractory to dioxin treatment
-
Moffat ID, Boutros PC, Celius T, Linden J, Pohjanvirta R, Okey AB. microRNAs in adult rodent liver are refractory to dioxin treatment. Toxicol Sci. 2007;99(2):470-487.
-
(2007)
Toxicol Sci
, vol.99
, Issue.2
, pp. 470-487
-
-
Moffat, I.D.1
Boutros, P.C.2
Celius, T.3
Linden, J.4
Pohjanvirta, R.5
Okey, A.B.6
-
116
-
-
30944469849
-
Estrogen carcinogenesis in breast cancer
-
Yager JD, Davidson NE. Estrogen carcinogenesis in breast cancer. N Engl J Med. 2006;354(3):270-282.
-
(2006)
N Engl J Med
, vol.354
, Issue.3
, pp. 270-282
-
-
Yager, J.D.1
Davidson, N.E.2
-
117
-
-
67651006246
-
Xenoestrogen-induced epigenetic repression of microRNA-9-3 in breast epithelial cells
-
Hsu PY, Deatherage DE, Rodriguez BA, Liyanarachchi S, Weng YI, Zuo T, Liu J, Cheng AS, Huang TH. Xenoestrogen-induced epigenetic repression of microRNA-9-3 in breast epithelial cells. Cancer Res. 2009;69(14):5936-5945.
-
(2009)
Cancer Res
, vol.69
, Issue.14
, pp. 5936-5945
-
-
Hsu, P.Y.1
Deatherage, D.E.2
Rodriguez, B.A.3
Liyanarachchi, S.4
Weng, Y.I.5
Zuo, T.6
Liu, J.7
Cheng, A.S.8
Huang, T.H.9
-
118
-
-
40949157661
-
Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome
-
Cheng AS, Culhane AC, Chan MW, Venkataramu CR, Ehrich M, Nasir A, Rodriguez BA, Liu J, Yan PS, Quackenbush J, Nephew KP, Yeatman TJ, Huang TH. Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome. Cancer Res. 2008;68(6):1786-1796.
-
(2008)
Cancer Res
, vol.68
, Issue.6
, pp. 1786-1796
-
-
Cheng, A.S.1
Culhane, A.C.2
Chan, M.W.3
Venkataramu, C.R.4
Ehrich, M.5
Nasir, A.6
Rodriguez, B.A.7
Liu, J.8
Yan, P.S.9
Quackenbush, J.10
Nephew, K.P.11
Yeatman, T.J.12
Huang, T.H.13
-
119
-
-
0032692436
-
Molecular epidemiology of lung cancer
-
Shields PG. Molecular epidemiology of lung cancer. Ann Oncol. 1999;10 Suppl 5:S7-11.
-
(1999)
Ann Oncol
, vol.10
, Issue.SUPPL. 5
-
-
Shields, P.G.1
-
120
-
-
0030846720
-
Molecular damage in the bronchial epithelium of current and former smokers
-
Wistuba, II, Lam S, Behrens C, Virmani AK, Fong KM, LeRiche J, Samet JM, Srivastava S, Minna JD, Gazdar AF. Molecular damage in the bronchial epithelium of current and former smokers. J Natl Cancer Inst. 1997;89(18):1366-1373.
-
(1997)
J Natl Cancer Inst
, vol.89
, Issue.18
, pp. 1366-1373
-
-
Wistuba, I.I.1
Lam, S.2
Behrens, C.3
Virmani, A.K.4
Fong, K.M.5
Leriche, J.6
Samet, J.M.7
Srivastava, S.8
Minna, J.D.9
Gazdar, A.F.10
-
121
-
-
60549084170
-
MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium
-
Schembri F, Sridhar S, Perdomo C, Gustafson AM, Zhang X, Ergun A, Lu J, Liu G, Bowers J, Vaziri C, Ott K, Sensinger K, Collins JJ, Brody JS, Getts R, Lenburg ME, Spira A. MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc Natl Acad Sci U S A. 2009;106(7):2319-2324.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.7
, pp. 2319-2324
-
-
Schembri, F.1
Sridhar, S.2
Perdomo, C.3
Gustafson, A.M.4
Zhang, X.5
Ergun, A.6
Lu, J.7
Liu, G.8
Bowers, J.9
Vaziri, C.10
Ott, K.11
Sensinger, K.12
Collins, J.J.13
Brody, J.S.14
Getts, R.15
Lenburg, M.E.16
Spira, A.17
-
122
-
-
61449208911
-
Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke
-
Izzotti A, Calin GA, Arrigo P, Steele VE, Croce CM, De Flora S. Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke. FASEB J. 2009;23(3):806-812.
-
(2009)
FASEB J
, vol.23
, Issue.3
, pp. 806-812
-
-
Izzotti, A.1
Calin, G.A.2
Arrigo, P.3
Steele, V.E.4
Croce, C.M.5
De Flora, S.6
-
123
-
-
77649196362
-
Chemoprevention of cigarette smoke-induced alterations of MicroRNA expression in rat lungs
-
Izzotti A, Calin GA, Steele VE, Cartiglia C, Longobardi M, Croce CM, De Flora S. Chemoprevention of cigarette smoke-induced alterations of MicroRNA expression in rat lungs. Cancer Prev Res (Phila Pa). 2010;3(1):62-72.
-
(2010)
Cancer Prev Res (Phila Pa)
, vol.3
, Issue.1
, pp. 62-72
-
-
Izzotti, A.1
Calin, G.A.2
Steele, V.E.3
Cartiglia, C.4
Longobardi, M.5
Croce, C.M.6
De Flora, S.7
-
124
-
-
70349315533
-
Relationships of microRNA expression in mouse lung with age and exposure to cigarette smoke and light
-
Izzotti A, Calin GA, Steele VE, Croce CM, De Flora S. Relationships of microRNA expression in mouse lung with age and exposure to cigarette smoke and light. FASEB J. 2009;23(9):3243-3250.
-
(2009)
FASEB J
, vol.23
, Issue.9
, pp. 3243-3250
-
-
Izzotti, A.1
Calin, G.A.2
Steele, V.E.3
Croce, C.M.4
De Flora, S.5
-
125
-
-
0026330605
-
Arsenite as the probable active species in the human carcinogenicity of arsenic: Mouse micronucleus assays on Na and K arsenite, orpiment, and Fowler's solution
-
Tinwell H, Stephens SC, Ashby J. Arsenite as the probable active species in the human carcinogenicity of arsenic: mouse micronucleus assays on Na and K arsenite, orpiment, and Fowler's solution. Environ Health Perspect. 1991;95:205-210.
-
(1991)
Environ Health Perspect
, vol.95
, pp. 205-210
-
-
Tinwell, H.1
Stephens, S.C.2
Ashby, J.3
-
126
-
-
0037182165
-
Arsenic co-exposure potentiates benzo[a]pyrene genotoxicity
-
Maier A, Schumann BL, Chang X, Talaska G, Puga A. Arsenic co-exposure potentiates benzo[a]pyrene genotoxicity. Mutat Res. 2002;517(1-2):101-111.
-
(2002)
Mutat Res
, vol.517
, Issue.1-2
, pp. 101-111
-
-
Maier, A.1
Schumann, B.L.2
Chang, X.3
Talaska, G.4
Puga, A.5
-
127
-
-
0026298357
-
Comutagenesis of sodium arsenite with ultraviolet radiation in Chinese hamster V79 cells
-
Li JH, Rossman TG. Comutagenesis of sodium arsenite with ultraviolet radiation in Chinese hamster V79 cells. Biol Met. 1991;4(4):197-200.
-
(1991)
Biol Met
, vol.4
, Issue.4
, pp. 197-200
-
-
Li, J.H.1
Rossman, T.G.2
-
128
-
-
0024415619
-
Mechanism of comutagenesis of sodium arsenite with nmethyl- n-nitrosourea
-
Li JH, Rossman TG. Mechanism of comutagenesis of sodium arsenite with nmethyl- n-nitrosourea. Biol Trace Elem Res. 1989;21:373-381.
-
(1989)
Biol Trace Elem Res
, vol.21
, pp. 373-381
-
-
Li, J.H.1
Rossman, T.G.2
-
129
-
-
33845312687
-
MicroRNA responses to cellular stress
-
Marsit CJ, Eddy K, Kelsey KT. MicroRNA responses to cellular stress. Cancer Res. 2006;66(22):10843-10848.
-
(2006)
Cancer Res
, vol.66
, Issue.22
, pp. 10843-10848
-
-
Marsit, C.J.1
Eddy, K.2
Kelsey, K.T.3
-
130
-
-
6044244941
-
Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells
-
Kasashima K, Nakamura Y, Kozu T. Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells. Biochem Biophys Res Commun. 2004;322(2):403-410.
-
(2004)
Biochem Biophys Res Commun
, vol.322
, Issue.2
, pp. 403-410
-
-
Kasashima, K.1
Nakamura, Y.2
Kozu, T.3
-
131
-
-
54849412067
-
Complementary analysis of microRNA and mRNA expression during phorbol 12- myristate 13-acetate (TPA)-induced differentiation of HL-60 cells
-
Chen A, Luo M, Yuan G, Yu J, Deng T, Zhang L, Zhou Y, Mitchelson K, Cheng J. Complementary analysis of microRNA and mRNA expression during phorbol 12- myristate 13-acetate (TPA)-induced differentiation of HL-60 cells. Biotechnol Lett. 2008;30(12):2045-2052.
-
(2008)
Biotechnol Lett
, vol.30
, Issue.12
, pp. 2045-2052
-
-
Chen, A.1
Luo, M.2
Yuan, G.3
Yu, J.4
Deng, T.5
Zhang, L.6
Zhou, Y.7
Mitchelson, K.8
Cheng, J.9
-
132
-
-
34250163202
-
Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation
-
Shah YM, Morimura K, Yang Q, Tanabe T, Takagi M, Gonzalez FJ. Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation. Mol Cell Biol. 2007;27(12):4238-4247.
-
(2007)
Mol Cell Biol
, vol.27
, Issue.12
, pp. 4238-4247
-
-
Shah, Y.M.1
Morimura, K.2
Yang, Q.3
Tanabe, T.4
Takagi, M.5
Gonzalez, F.J.6
-
133
-
-
73949158230
-
N-3 Polyunsaturated fatty acids modulate carcinogen-directed non-coding microRNA signatures in rat colon
-
Davidson LA, Wang N, Shah MS, Lupton JR, Ivanov I, Chapkin RS. n-3 Polyunsaturated fatty acids modulate carcinogen-directed non-coding microRNA signatures in rat colon. Carcinogenesis. 2009;30(12):2077-2084.
-
(2009)
Carcinogenesis
, vol.30
, Issue.12
, pp. 2077-2084
-
-
Davidson, L.A.1
Wang, N.2
Shah, M.S.3
Lupton, J.R.4
Ivanov, I.5
Chapkin, R.S.6
-
134
-
-
33750490454
-
PYK2 mediates antiapoptotic AKT signaling in response to benzo[a]pyrene diol epoxide in mammary epithelial cells
-
Burdick AD, Ivnitski-Steele ID, Lauer FT, Burchiel SW. PYK2 mediates antiapoptotic AKT signaling in response to benzo[a]pyrene diol epoxide in mammary epithelial cells. Carcinogenesis. 2006;27(11):2331-2340.
-
(2006)
Carcinogenesis
, vol.27
, Issue.11
, pp. 2331-2340
-
-
Burdick, A.D.1
Ivnitski-Steele, I.D.2
Lauer, F.T.3
Burchiel, S.W.4
-
135
-
-
34247648712
-
MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global genome-wide analysis
-
Debernardi S, Skoulakis S, Molloy G, Chaplin T, Dixon-McIver A, Young BD. MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global genome-wide analysis. Leukemia. 2007;21(5):912-916.
-
(2007)
Leukemia
, vol.21
, Issue.5
, pp. 912-916
-
-
Debernardi, S.1
Skoulakis, S.2
Molloy, G.3
Chaplin, T.4
Dixon-Mciver, A.5
Young, B.D.6
-
136
-
-
69049096130
-
Estradiol-regulated microRNAs control estradiol response in breast cancer cells
-
Bhat-Nakshatri P, Wang G, Collins NR, Thomson MJ, Geistlinger TR, Carroll JS, Brown M, Hammond S, Srour EF, Liu Y, Nakshatri H. Estradiol-regulated microRNAs control estradiol response in breast cancer cells. Nucleic Acids Res. 2009;37(14):4850-4861.
-
(2009)
Nucleic Acids Res
, vol.37
, Issue.14
, pp. 4850-4861
-
-
Bhat-Nakshatri, P.1
Wang, G.2
Collins, N.R.3
Thomson, M.J.4
Geistlinger, T.R.5
Carroll, J.S.6
Brown, M.7
Hammond, S.8
Srour, E.F.9
Liu, Y.10
Nakshatri, H.11
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