Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumours

Journal of Pathology

Volumn 220, Issue 1, 2010, Pages 58-70

  Subramanian, Subbaya ^a   Thayanithy, Venugopal ^a   West, Robert B ^b   Lee, Cheng Han ^c   Beck, Andrew H ^b   Zhu, Shirley ^b   Downs Kelly, Erinn ^d   Montgomery, Kelli ^b   Goldblum, John R ^d   Hogendoorn, Pancras C W ^e   Corless, Christopher L ^f   Oliveira, Andre M ^g   Dry, Sarah M ^h   Nielsen, Torsten O ^c   Rubin, Brian P ^d   Fletcher, Jonathan A ⁱ   Fletcher, Christopher D M ⁱ   Van De Rijn, Matt ^b  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VANCOUVER GENERAL HOSPITAL   (Canada)

^d LERNER RESEARCH INSTITUTE   (United States)

^e LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^f OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^g MAYO CLINIC   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Expression profiling; Malignant transformation; Microrna; Peripheral nerve sheath tumours

Indexed keywords

MICRORNA; MICRORNA 34A; PROTEIN P53; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ADULT; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE INACTIVATION; GENE LOSS; GENOME; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; MALIGNANT PERIPHERAL NERVE SHEATH TUMOR; METASTASIS; NERVE SHEATH TUMOR; NEURILEMOMA; NEUROFIBROMA; PERIPHERAL NERVE TUMOR; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; TRANSCRIPTOMICS;

ADULT; APOPTOSIS; CELL ADHESION; CELL PROLIFERATION; CLUSTER ANALYSIS; DOWN-REGULATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENES, P53; HUMANS; MALE; MICRORNAS; MIDDLE AGED; NEOPLASM PROTEINS; NERVE SHEATH NEOPLASMS; NEUROFIBROMA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTOR, EPIDERMAL GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, NEOPLASM; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 73649129263     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2633     Document Type: Article

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