CD24 affects CXCR4 function in pre-B lymphocytes and breast carcinoma cells

Journal of Cell Science

Volumn 119, Issue 2, 2006, Pages 314-325

  Schabath, Heidi ^a   Runz, Steffen ^a   Joumaa, Safwan ^a   Altevogt, Peter ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

CD24; Cholesterol; CXCR4; SDF 1

Indexed keywords

CD19 ANTIGEN; CD24 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; CHOLESTEROL; STROMAL CELL DERIVED FACTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; BREAST CARCINOGENESIS; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER GROWTH; CARCINOMA CELL; CELL ISOLATION; CELL LEVEL; CHEMOTAXIS; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; LIPID RAFT; LYMPHOCYTE MIGRATION; METASTASIS; MOUSE; NONHUMAN; PRE B LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCID MOUSE; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD24; B-LYMPHOCYTES; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL LINEAGE; CELL MOVEMENT; CHEMOKINES, CXC; CHOLESTEROL; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HUMANS; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; RECEPTORS, CXCR4; RECOMBINANT FUSION PROTEINS; RNA, SMALL INTERFERING;

ANIMALIA;

EID: 32244439441     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02741     Document Type: Article

References (56)

1. Abraham, B. K., Fritz, P., McClellan, M., Hauptvogel, P., Athelogou, M. and Brauch, H. (2005). Prevalence of CD44+/CD24-/low cells in breast cancer may not be associated with clinical outcome but may favor distant metastasis. Clin. Cancer Res. 11, 1154-1159.
2. Abrami, L., Fivaz, M., Kobayashi, T., Kinoshita, T., Parton, R. G. and van der Goot, F. G. (2001). Cross-talk between caveolae and glycosylphosphatidylinositol-rich domains. J. Biol. Chem. 276, 30729-3036.
3. Aigner, S., Sthoeger, Z. M., Fogel, M., Weber, E., Zarn, J., Ruppert, M., Zeller, Y., Vestweber, D., Stahel, R., Sammar, M. et al. (1997). CD24, a mucin-type glycoprotein, is a ligand for P-selectin on human tumor cells. Blood 89, 3385-3395.
4. Al-Hajj, M., Wicha, M. S., Benito-Hernandez, A., Morrison, S. J. and Clarke, M. F. (2003). Prospective identification of tumorigenic breast cancer cells. Proc. Natl. Acad. Sci. USA 100, 3983-3988.
5. Alterman, L. A., Crispe, I. N. and Kinnon, C. (1990). Characterization of the marine heat-stable antigen: an hematolymphoid differentiation antigen defined by the J11d, M1/69 and B2A2 antibodies. Eur. J. Immunol. 20, 1597-1602.
6. Berger, E. A., Murphy, P. M. and Farber, J. M. (1999). Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annu. Rev. Immunol. 17, 657-700.
7. Brown, D. A. and London, E. (1998). Functions of lipid rafts in biological membranes. Annu. Rev. Cell Dev. Biol. 14, 111-136.
8. Broxmeyer, H. E., Youn, B. S., Kim, C., Hangoc, G., Cooper, S. and Mantel, C. (2001). Chemokine regulation of hematopoiesis and the involvement of pertussis toxin-sensitive G alpha i proteins. Ann. New York Acad. Sci. 938, 117-127.
9. Chernock, R. D., Cherla, R. P. and Ganju, R. K. (2001). SHP2 and cbl participate in alpha-chemokine receptor CXCR4-mediated signaling pathways. Blood 97, 608-615.
10. Choi, Y. L., Kim, S. H., Shin, Y. K., Hong, Y. C., Lee, S. J., Kang, S. Y. and Ahn, G. (2005). Cytoplasmic CD24 expression in advanced ovarian serous borderline tumors. Gynecol. Oncol. 97, 379-386.
11. Darash-Yahana, M., Pikarsky, E., Abramovitch, R., Zeira, E., Pal, B., Karplus, R., Beider, K., Avniel, S., Kasem, S., Galun, E. et al. (2004). Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis. FASEB J. 18, 1240-1242.
12. Egerton, M., Shortman, K. and Scollay, R. (1990). The kinetics of immature marine thymocyte development in vivo. Int. Immunol. 2, 501-517.
13. Epstein, R. J. (2004). The CXCL12-CXCR4 chemotactic pathway as a target of adjuvant breast cancer therapies. Nat. Rev. Cancer 4, 901-909.
14. Fernandis, A. Z., Cherla, R. P. and Ganju, R. K. (2003). Differential regulation of CXCR4-mediated T-cell chemotaxis and mitogen-activated protein kinase activation by the membrane tyrosine phosphatase, CD45. J. Biol. Chem. 278, 9536-9543.
15. Friederichs, J., Zeller, Y., Hafezi-Moghadam, A., Grone, H. J., Ley, K. and Altevogt, P. (2000). The CD24/P-selectin binding pathway initiates lung arrest of human A125 adenocarcinoma cells. Cancer Res. 60, 6714-6722.
16. Ganju, R. K., Brubaker, S. A., Meyer, J., Dart, P., Yang, Y., Qin, S., Newman, W. and Groopman, J. E. (1998). The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways. J. Biol. Chem. 273, 23169-23175.
17. Gerard, C. and Rollins, B. J. (2001). Chemokines and disease. Nat. Immunol. 2, 108-115.
18. Hahne, M., Wenger, R. H., Vestweber, D. and Nielsen, P. J. (1994). The heat-stable antigen can alter very late antigen 4-mediated adhesion. J. Exp. Med. 179, 1391-1395.
19. Harder, T. and Engelhardt, K. R. (2004). Membrane domains in lymphocytes - from lipid rafts to protein scaffolds. Traffic 5, 265-275.
20. Kadmon, G., von Bohlen and Halbach, F., Schachner, M. and Altevogt, P. (1994). Differential, LFA-1-sensitive effects of antibodies to nectadrin, the heat-stable antigen, on B lymphoblast aggregation and signal transduction. Biochem. Biophys. Res. Commun. 198, 1209-1215.
21. Kay, R., Takei, F. and Humphries, R. K. (1990). Expression cloning of a cDNA encoding M1/69-J11d heat-stable antigens. J. Immunol. 145, 1952-1959.
22. Kristiansen, G., Denkert, C., Schluns, K., Dahl, E., Pilarsky, C. and Hauptmann, S. (2002). CD24 is expressed in ovarian cancer and is a new independent prognostic marker of patient survival. Am. J. Pathol. 161, 1215-1221.
23. Kristiansen, G., Winzer, K. J., Mayordomo, E., Bellach, J., Schluns, K., Denkert, C., Dahl, E., Pilarsky, C., Altevogt, P., Guski, H. et al. (2003). CD24 expression is a new prognostic marker in breast cancer. Clin. Cancer Res. 9, 4906-4913.
24. Kristiansen, G., Pilarsky, C., Pervan, J., Sturzebecher, B., Stephan, C., Jung, K., Loening, S., Rosenthal, A. and Dietel, M. (2004a). CD24 expression is a significant predictor of PSA relapse and poor prognosis in low grade or organ confined prostate cancer. Prostate 58, 183-192.
25. Kristiansen, G., Sammar, M. and Altevogt, P. (2004b). Tumour biological aspects of CD24, a mucin-like adhesion molecule. J. Mol. Histol. 35, 255-262.
26. Kucia, M., Jankowski, K., Reca, R., Wysoczynski, M., Bandura, L., Allendorf, D. J., Zhang, J., Ratajczak, J. and Ratajczak, M. Z. (2004). CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion. J. Mol. Histol. 35, 233-245.
27. Kurzchalia, T. V. and Parton, R. G. (1999). Membrane microdomains and caveolae. Curr. Opin. Cell Biol. 11, 424-431.
28. Li, O., Zheng, P. and Liu, Y. (2004). CD24 expression on T cells is required for optimal T cell proliferation in lymphopenic host. J. Exp. Med. 200, 1083-1089.
29. Lu, L., Smithson, G., Kincade, P. W. and Osmond, D. G. (1998). Two models of murine B lymphopoiesis: a correlation. Eur. J. Immunol. 28, 1755-1761.
30. Magnaldo, T. and Barrandon, Y. (1996). CD24 (heat stable antigen, nectadrin), a novel keratinocyte differentiation marker, is preferentially expressed in areas of the hair follicle containing the colony-forming cells. J. Cell Sci. 109, 3035-3045.
31. Manes, S., Lacalle, R. A., Gomez-Mouton, C., del Real, G., Mira, E. and Martinez, A. C. (2001). Membrane raft microdomains in chemokine receptor function. Semin. Immunol. 13, 147-157.
32. Maric, D., Kaiserlian, D. and Croitoru, K. (1996). Intestinal epithelial cell line induction of T cell differentiation from bone marrow precursors. Cell Immunol. 172, 172-179.
33. Moser, B., Loetscher, M., Piali, L. and Loetscher, P. (1998). Lymphocyte responses to chemokines. Int. Rev. Immunol. 16, 323-344.
34. Muller, A., Homey, B., Soto, H., Ge, N., Catron, D., Buchanan, M. E., McClanahan, T., Murphy, E., Yuan, W., Wagner, S. N. et al. (2001). Involvement of chemokine receptors in breast cancer metastasis. Nature 410, 50-56.
35. Muller, C. P., Stephany, D. A., Winkler, D. F., Hoeg, J. M., Demosky, S. J., Jr and Wunderlich, J. R. (1984). Filipin as a flow microfluorometry probe for cellular cholesterol. Cytometry 5, 42-54.
36. Nagasawa, T., Nakajima, T., Tachibana, K., Iizasa, H., Bleul, C. C., Yoshie, O., Matsushima, K., Yoshida, N., Springer, T. A. and Kishimoto, T. (1996). Molecular cloning and characterization of a marine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a marine homolog of the human immunodeficiency virus 1 entry coreceptor fusin. Proc. Natl. Acad. Sci. USA 93, 14726-14729.
37. Nguyen, D. H. and Taub, D. (2002). CXCR4 function requires membrane cholesterol: implications for HIV infection. J. Immunol. 168, 4121-4126.
38. Nguyen, D. H. and Taub, D. (2003). Membrane incorporation of 22-hydroxycholesterol inhibits chemokine receptor activity. Exp. Cell Res. 285, 268-277.
39. Nielsen, P. J., Lorenz, B., Muller, A. M., Wenger, R. H., Brombacher, F., Simon, M., von der Weid, T., Langhorne, W. J., Mossmann, H. and Kohler, G. (1997). Altered erythrocytes and a leaky block in B-cell development in CD24/HSA-deficient mice. Blood 89, 1058-1067.
40. Orimo, A., Gupta, P. B., Sgroi, D. C., Arenzana-Seisdedos, F., Delaunay, T., Naeem, R., Carey, V. J., Richardson, A. L. and Weinberg, R. A. (2005). Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121, 335-348.
41. Pierres, M., Naquet, P., Barbet, J., Marchetto, S., Marics, I., Devaux, C., Barad, M., Hyman, R. and Rougon, G. (1987). Evidence that marine hematopoietic cell subset marker J11d is attached to a glycosyl-phosphatidylinositol membrane anchor. Eur. J. Immunol. 17, 1781-1785.
42. Poncet, C., Frances, V., Gristina, R., Scheiner, C., Pellissier, J. F. and Figarella-Branger, D. (1996). CD24, a glycosylphosphatidylinositol-anchored molecules is transiently expressed during the development of human central nervous system and is a marker of human neural cell lineage tumors. Acta Neuropathol. (Berl.) 91, 400-408.
43. Rossi, D. and Zlotnik, A. (2000). The biology of chemokines and their receptors. Annu. Rev. Immunol. 18, 217-242.
44. Scala, S., Ottaiano, A., Ascierto, P. A., Cavalli, M., Simeone, E., Giuliano, P., Napolitano, M., Franco, R., Botti, G. and Castello, G. (2005). Expression of CXCR4 predicts poor prognosis in patients with malignant melanoma. Clin. Cancer Res. 11, 1835-1841.
45. Scotton, C. J., Wilson, J. L., Scott, K., Stamp, G., Wilbanks, G. D., Fricker, S., Bridger, G. and Balkwill, F. R. (2002). Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer. Cancer Res. 62, 5930-5938.
46. Shamri, R., Grabovsky, V., Feigelson, S. W., Dwir, O., Van Kooyk, Y. and Alon, R. (2002). Chemokine stimulation of lymphocyte alpha 4 integrin avidity but not of leukocyte function-associated antigen-1 avidity to endothelial ligands under shear flow requires cholesterol membrane rafts. J. Biol. Chem. 277, 40027-40035.
47. Shirasawa, T., Akashi, T., Sakamoto, K., Takahashi, H., Maruyama, N. and Hirokawa, K. (1993). Gene expression of CD24 core peptide molecule in developing brain and developing non-neural tissues. Dev. Dyn. 198, 1-13.
48. Simons, K. and Ikonen, E. (2000). How cells handle cholesterol. Science 290, 1721-1726.
49. Smith, M. C., Luker, K. E., Garbow, J. R., Prior, J. L., Jackson, E., Piwnica-Worms, D. and Luker, G. D. (2004). CXCR4 regulates growth of both primary and metastatic breast cancer. Cancer Res. 64, 8604-8612.
50. Stumm, R. K., Rummel, J., Junker, V., Culmsee, C., Pfeiffer, M., Krieglstein, J., Hollt, V. and Schutz, S. (2002). A dual role for the SDF-1/CXCR4 chemokine receptor system in adult brain: isoform-selective regulation of SDF-1 expression modulates CXCR4-dependent neuronal plasticity and cerebral leukocyte recruitment after focal ischemia. J. Neurosci. 22, 5865-5878.
51. Suzuki, T., Kiyokawa, N., Taguchi, T., Sekino, T., Katagiri, Y. U. and Fujimoto, J. (2001). CD24 induces apoptosis in human B cells via the glycolipid-enriched membrane domains/rafts-mediated signaling system. J. Immunol. 166, 5567-5577.
52. Taub, D. D., Sayers, T. J., Carter, C. R. and Ortaldo, J. R. (1995). Alpha and beta chemokines induce NK cell migration and enhance NK-mediated cytolysis. J. Immunol. 155, 3877-3888.
53. Weber, E., Lehmann, H. P., Beck-Sickinger, A. G., Wawrzynczak, E. J., Waibel, R., Folkers, G. and Stahel, R. A. (1993). Antibodies to the protein core of the small cell lung cancer workshop antigen cluster-w4 and to the leukocyte workshop antigen CD24 recognize the same short protein sequence leucine-alanine-proline. Clin. Exp. Immunol. 93, 279-285.
54. Wessel, D. and Flugge, U. I. (1984). A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids. Anal. Biochem. 138, 141-143.
55. Wysoczynski, M., Reca, R., Ratajczak, J., Kucia, M., Shirvaikar, N., Honczarenko, M., Mills, M., Wanzeck, J., Janowska-Wieczorek, A. and Ratajczak, M. Z. (2005). Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient. Blood 105, 40-48.
56. Zeelenberg, I. S., Ruuls-Van Stalle, L. and Roos, E. (2003). The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases. Cancer Res. 63, 3833-3839.