The role of Sirt1: At the crossroad between promotion of longevity and protection against Alzheimer's disease neuropathology

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1804, Issue 8, 2010, Pages 1690-1694

  Wang, Jun ^a   Fivecoat, Hayley ^a   Ho, Lap ^a   Pan, Yong ^a   Ling, Emi ^a   Pasinetti, Giulio Maria ^a,b  

^a Center of Excellence for Novel Approaches to Neurodiagnostics and Neurotherapeutics   (United States)

^b GERIATRIC RESEARCH EDUCATION AND CLINICAL CENTER   (United States)

Author keywords

Alzheimer's disease; Caloric restriction; Dementia; Neurodegeneration; Sirtuins

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; CENTRAL NERVOUS SYSTEM AGENTS; FISETIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; RESVERATROL; SIRTUIN; SIRTUIN 1; SIRTUIN 1 ACTIVATOR; UNCLASSIFIED DRUG;

AGING; ALZHEIMER DISEASE; AMYLOIDOSIS; APOPTOSIS; CALORIC RESTRICTION; CANCER PREVENTION; CELL FUNCTION; CELL METABOLISM; CELL STRESS; CELL SURVIVAL; COGNITIVE DEFECT; DEGENERATIVE DISEASE; DIABETES MELLITUS; DISEASE COURSE; DRUG MECHANISM; DRUG RESEARCH; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; FOOD COMPOSITION; HUMAN; HUNTINGTON CHOREA; LONGEVITY; METABOLIC REGULATION; NEUROPATHOLOGY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TARGETING; REGULATORY MECHANISM; REVIEW; SENILE PLAQUE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOIDOSIS; ANIMALS; CALORIC RESTRICTION; HUMANS; LONGEVITY; NAD; SIRTUIN 1; STILBENES;

MAMMALIA;

EID: 77953421120     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2009.11.015     Document Type: Review

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