-
1
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase are associated with familial amyotrophic lateral sclerosis
-
Rosen D.R. Siddique T. Patterson D. Figlewicz D.A. Sapp P. Hentati A. et al. Mutations in Cu/Zn superoxide dismutase are associated with familial amyotrophic lateral sclerosis. Nature 1993; 362:59–62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
-
2
-
-
85007771541
-
Oxidative stress and motor neurone disease
-
Brain Pathol (in press).
-
Cookson MR Shaw PJ. Oxidative stress and motor neurone disease. Brain Pathol (in press).
-
-
-
Cookson, M.R.1
Shaw, P.J.2
-
3
-
-
0028960506
-
Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice
-
Brown RH. Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice. Cell 1995; 80:687–692.
-
(1995)
Cell
, vol.80
, pp. 687-692
-
-
Brown, R.H.1
-
5
-
-
0031959591
-
Linkage of the gene for an autosomal dominant form of juvenile amyotrophic lateral sclerosis to chromosome 9q34
-
Chance P.F. Rabin B.A. Ryan S.G. Ding Y. Scavina M. Crain B. et al. Linkage of the gene for an autosomal dominant form of juvenile amyotrophic lateral sclerosis to chromosome 9q34.Am J Hum Genet 1998; 62:633–640.
-
(1998)
Am J Hum Genet
, vol.62
, pp. 633-640
-
-
Chance, P.F.1
Rabin, B.A.2
Ryan, S.G.3
Ding, Y.4
Scavina, M.5
Crain, B.6
-
6
-
-
0028001606
-
Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis
-
Figlewicz D.A. Rouleau G.A. Krizus A. Julien J.P. Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis.Hum Mol Genet 1994; 3:1757–1761.
-
(1994)
Hum Mol Genet
, vol.3
, pp. 1757-1761
-
-
Figlewicz, D.A.1
Rouleau, G.A.2
Krizus, A.3
Julien, J.P.4
-
7
-
-
85007769216
-
Novel insertion in the KSP repeat region of the neurofilament heavy gene in amyotrophic lateral sclerosis (ALS)
-
Neuroreport (in press).
-
Tomkins J. Usher P.A. Slade J.Y. Ince P.G. Curtis A. Bushby K. et al. Novel insertion in the KSP repeat region of the neurofilament heavy gene in amyotrophic lateral sclerosis (ALS).Neuroreport (in press).
-
-
-
Tomkins, J.1
Usher, P.A.2
Slade, J.Y.3
Ince, P.G.4
Curtis, A.5
Bushby, K.6
-
9
-
-
0032567807
-
Mutant A.P. endonuclease in patients with amyotrophic lateral sclerosis
-
Olkowski Z.L. Mutant A.P. endonuclease in patients with amyotrophic lateral sclerosis. Neuroreport 1998; 9:239–242.
-
(1998)
Neuroreport
, vol.9
, pp. 239-242
-
-
Olkowski, Z.L.1
-
11
-
-
0029082389
-
Oxidative damage to protein in sporadic motor neuron disease spinal cord
-
Shaw P.J. Ince P.G. Falkous G. Mantle D. Oxidative damage to protein in sporadic motor neuron disease spinal cord. Ann Neurol 1995; 38:691–695.
-
(1995)
Ann Neurol
, vol.38
, pp. 691-695
-
-
Shaw, P.J.1
Ince, P.G.2
Falkous, G.3
Mantle, D.4
-
12
-
-
0031569838
-
Immunocytochemical study of the distribution of the free radical scavenging enzymes Cu/Zn superoxide dismutase (SOD1), Mn superoxide dismutase (Mn SOD) and catalase in the normal human spinal cord and in motor neurone disease
-
Shaw P.J. Chinnery R.M. Thagesen H. Borthwick G. Ince P.G. Immunocytochemical study of the distribution of the free radical scavenging enzymes Cu/Zn superoxide dismutase (SOD1), Mn superoxide dismutase (Mn SOD) and catalase in the normal human spinal cord and in motor neurone disease.J Neurol Sci 1997; 147:115–125.
-
(1997)
J Neurol Sci
, vol.147
, pp. 115-125
-
-
Shaw, P.J.1
Chinnery, R.M.2
Thagesen, H.3
Borthwick, G.4
Ince, P.G.5
-
14
-
-
0030927075
-
Glutamate, excitotoxicity and amyotrophic lateral sclerosis
-
Shaw P.J. Ince P.G. Glutamate, excitotoxicity and amyotrophic lateral sclerosis. J Neurol 1997; 244(suppl 2): S3–14.
-
(1997)
J Neurol
, vol.244
, Issue.suppl 2
, pp. S3-14
-
-
Shaw, P.J.1
Ince, P.G.2
-
15
-
-
0026597010
-
Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
-
Rothstein J.D. Martin L.J. Kuncl R.W. Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N Engl J Med 1992; 326:1464–1468.
-
(1992)
N Engl J Med
, vol.326
, pp. 1464-1468
-
-
Rothstein, J.D.1
Martin, L.J.2
Kuncl, R.W.3
-
17
-
-
0029067210
-
CSF and plasma amino acid levels in motor neuron disease: elevation of CSF glutamate in a subset of patients
-
Shaw P.J. Forrest V. Ince P.G. Richardson J.P. Wastell H.J. CSF and plasma amino acid levels in motor neuron disease: elevation of CSF glutamate in a subset of patients. Neurodegeneration 1995; 4:209–216.
-
(1995)
Neurodegeneration
, vol.4
, pp. 209-216
-
-
Shaw, P.J.1
Forrest, V.2
Ince, P.G.3
Richardson, J.P.4
Wastell, H.J.5
-
18
-
-
0032032013
-
Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter in amyotrophic lateral sclerosis
-
Lin C.L.G. Bristol L.A. Dykes-Hoberg M. Crawford T. Clawson L. Rothstein J.D. Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter in amyotrophic lateral sclerosis. Neuron 1998; 20:589–602.
-
(1998)
Neuron
, vol.20
, pp. 589-602
-
-
Lin, C.L.G.1
Bristol, L.A.2
Dykes-Hoberg, M.3
Crawford, T.4
Clawson, L.5
Rothstein, J.D.6
-
19
-
-
0032549709
-
Identification of alternative splicing forms of GLT-1 mRNA in the spinal cord of amyotrophic lateral sclerosis patients
-
Nagai M. Abe K. Okamoto K. Itoyama Y. Identification of alternative splicing forms of GLT-1 mRNA in the spinal cord of amyotrophic lateral sclerosis patients. Neurosci Lett 1998; 244:165–168.
-
(1998)
Neurosci Lett
, vol.244
, pp. 165-168
-
-
Nagai, M.1
Abe, K.2
Okamoto, K.3
Itoyama, Y.4
-
20
-
-
85007731180
-
Molecular factors underlying the selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis
-
(in press).
-
Shaw PJ Eggett CJ. Molecular factors underlying the selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis. J Neurol (in press).
-
J Neurol
-
-
Shaw, P.J.1
Eggett, C.J.2
-
21
-
-
0030789347
-
Calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors: a molecular determinant of selective vulnerability in amyotrophic lateral sclerosis
-
Williams T.L. Day N.C. Ince P.G. Kamboj R.K. Shaw P.J. Calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors: a molecular determinant of selective vulnerability in amyotrophic lateral sclerosis.Ann Neurol 1997; 42:200–207.
-
(1997)
Ann Neurol
, vol.42
, pp. 200-207
-
-
Williams, T.L.1
Day, N.C.2
Ince, P.G.3
Kamboj, R.K.4
Shaw, P.J.5
-
23
-
-
0029977337
-
Dose-ranging study of riluzole in amyotrophic lateral sclerosis
-
Lacomblez L, Bensimon G, Leigh P.N., Guillet P, Meininger V, ALS/riluzole Study Group II.Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Lancet 1996; 347:1425–1432.
-
(1996)
Lancet
, vol.347
, pp. 1425-1432
-
-
-
26
-
-
0030050727
-
Benefit of vitamin E, riluzole and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
-
Gurney M.E. Cutting F.B. Zhai P. Doble A. Taylor C.P. Andrus P.K. et al. Benefit of vitamin E, riluzole and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis.Ann Neurol 1996; 39:147–158.
-
(1996)
Ann Neurol
, vol.39
, pp. 147-158
-
-
Gurney, M.E.1
Cutting, F.B.2
Zhai, P.3
Doble, A.4
Taylor, C.P.5
Andrus, P.K.6
-
28
-
-
0030831352
-
Mutant superoxide dismutase-1-linked familial amyotrophic lateral sclerosis: molecular mechanisms of neuronal death and protection
-
Ghadge G.D. Lee J.P. Bindokas V.P. Jordan J. Ma L. Miller R.J. et al. Mutant superoxide dismutase-1-linked familial amyotrophic lateral sclerosis: molecular mechanisms of neuronal death and protection.J Neurosci 1997; 17:8756–8766.
-
(1997)
J Neurosci
, vol.17
, pp. 8756-8766
-
-
Ghadge, G.D.1
Lee, J.P.2
Bindokas, V.P.3
Jordan, J.4
Ma, L.5
Miller, R.J.6
|