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Volumn 197, Issue , 2010, Pages 345-398

Improving oral delivery

Author keywords

Absorption enhancer; Biorecognition; Delayed release; Enzyme mediated release; Floating delivery systems; G I physiology; Gastroretentive; Hydrogel; Microparticle; Nanoparticle; Osmotic pump; PH dependent release; Targeting

Indexed keywords

APREPITANT; BENSERAZIDE PLUS LEVODOPA; BUDENOFALK; BUDESONIDE; CAPTOPRIL; CHITOSAN; CIPROFLOXACIN; DIAZEPAM; DILTIAZEM; DOXAZOSIN; ETHYL CELLULOSE; EUDRAGIT; FENOFIBRATE; GLIPIZIDE; HYDROXYPROPYLMETHYLCELLULOSE; MEGACE ES; MEGESTROL ACETATE; MESALAZINE; METHYLPHENIDATE; METOPROLOL; MISOPROSTOL; NANOPARTICLE; NIFEDIPINE; PALIPERIDONE; PHENYLPROPANOLAMINE; PIRETANIDE; POLYGLACTIN; RAPAMYCIN; TOLBUTAMIDE; TRIGLIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERAPAMIL; DRUG;

EID: 77953258460     PISSN: 01712004     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-00477-3_12     Document Type: Review
Times cited : (29)

References (202)
  • 1
    • 24744436916 scopus 로고    scopus 로고
    • Effect of simulated gastrointestinal conditions on drug release from pectin/ethylcellulose as film coating for drug delivery to the colon
    • Ahmed IS (2005) Effect of simulated gastrointestinal conditions on drug release from pectin/ ethylcellulose as film coating for drug delivery to the colon. Drug Dev Ind Pharm 31:465-470
    • (2005) Drug Dev Ind Pharm , vol.31 , pp. 465-470
    • Ahmed, I.S.1
  • 3
    • 0032103486 scopus 로고    scopus 로고
    • Novel pH-sensitive hydrogels with adjustable swelling kinetics
    • Akala EO, Kopeckova P, Kopecek J (1998) Novel pH-sensitive hydrogels with adjustable swelling kinetics. Biomaterials 19:1037-1047
    • (1998) Biomaterials , vol.19 , pp. 1037-1047
    • Akala, E.O.1    Kopeckova, P.2    Kopecek, J.3
  • 4
    • 0000847253 scopus 로고
    • The structure and function of gastrointestinal mucus
    • Boedeker EC (ed), CRC, Boca Raton, FL
    • Allen A (1984) The structure and function of gastrointestinal mucus. In: Boedeker EC (ed) Attachment of organisms to the gut mucosa. CRC, Boca Raton, FL, pp 4-10
    • (1984) Attachment of Organisms to the Gut Mucosa , pp. 4-10
    • Allen, A.1
  • 5
    • 0028948839 scopus 로고
    • A theoretical basis for a biopharmaceutic drug classification: The correlation in-vitro drug product dissolution and in vivo bioavailability
    • Amidon GL, Lennernäs H, Shah VP, Crison JR (1995) A theoretical basis for a biopharmaceutic drug classification: the correlation in-vitro drug product dissolution and in vivo bioavailability. Pharm Res 12:413-420
    • (1995) Pharm Res , vol.12 , pp. 413-420
    • Amidon, G.L.1    Lennernäs, H.2    Shah, V.P.3    Crison, J.R.4
  • 6
    • 56849100137 scopus 로고    scopus 로고
    • Time-controlled pulsatile delivery systems for bioactive compounds
    • Anal AK (2007) Time-controlled pulsatile delivery systems for bioactive compounds. Recent Pat Drug Deliv Formul 1:73-79
    • (2007) Recent Pat Drug Deliv Formul , vol.1 , pp. 73-79
    • Anal, A.K.1
  • 7
    • 44749087481 scopus 로고    scopus 로고
    • Design and production of nanoparticles formulated from nano-emulsion templates-A review
    • Anton N, Benoit JP, Saulnier P (2008) Design and production of nanoparticles formulated from nano-emulsion templates - A review. J Control Release 128:185-199
    • (2008) J Control Release , vol.128 , pp. 185-199
    • Anton, N.1    Benoit, J.P.2    Saulnier, P.3
  • 9
    • 33947507370 scopus 로고    scopus 로고
    • Multiparticulate formulation approach to colon specific drug delivery: Current perspectives
    • Asghar LFA, Chandran S (2006) Multiparticulate formulation approach to colon specific drug delivery: current perspectives. J Pharm Pharm Sci 9:327-338
    • (2006) J Pharm Pharm Sci , vol.9 , pp. 327-338
    • Asghar, L.F.A.1    Chandran, S.2
  • 10
    • 0033816196 scopus 로고    scopus 로고
    • Intestinal permeation enhancers
    • Aungst BJ (2000) Intestinal permeation enhancers. J Pharm Sci 89:429-442
    • (2000) J Pharm Sci , vol.89 , pp. 429-442
    • Aungst, B.J.1
  • 14
    • 75049085414 scopus 로고    scopus 로고
    • Poly (vinyl alcohol) hydrogels for pH dependent colon targeted drug delivery
    • doi:10.1007/s10856-008-3496-0
    • Basak P, Adhikari B (2008) Poly (vinyl alcohol) hydrogels for pH dependent colon targeted drug delivery. J Mater Sci Mater Med. doi:10.1007/s10856-008-3496-0
    • (2008) J Mater Sci Mater Med
    • Basak, P.1    Adhikari, B.2
  • 15
    • 26644452975 scopus 로고    scopus 로고
    • Thiomers: A new generation of mucoadhesive polymers
    • Bernkop-Schnürch A (2005) Thiomers: a new generation of mucoadhesive polymers. Adv Drug Deliv Rev 57:1569-1582
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 1569-1582
    • Bernkop-Schnürch, A.1
  • 16
    • 50849144023 scopus 로고    scopus 로고
    • World wide experience with inactivated poliovirus vaccine
    • Bonnet MC, Dutta A (2008) World wide experience with inactivated poliovirus vaccine. Vaccine 26:4978-4983
    • (2008) Vaccine , vol.26 , pp. 4978-4983
    • Bonnet, M.C.1    Dutta, A.2
  • 17
    • 33144477406 scopus 로고    scopus 로고
    • Research strategies for safety evaluation of nanomaterials, Part V: Role of dissolution in biological fate and effects of nanoscale particles
    • Borm P, Klaessig FC, Landry TD, Moudgil B, Pauluhn J, Thomas K, Trottier R, Wood S (2006) Research strategies for safety evaluation of nanomaterials, Part V: role of dissolution in biological fate and effects of nanoscale particles. Toxicol Sci 90:23-32
    • (2006) Toxicol Sci , vol.90 , pp. 23-32
    • Borm, P.1    Klaessig, F.C.2    Landry, T.D.3    Moudgil, B.4    Pauluhn, J.5    Thomas, K.6    Trottier, R.7    Wood, S.8
  • 18
    • 31144454861 scopus 로고    scopus 로고
    • Polymer colon drug delivery systems and their application to peptides, proteins, and nucleic acids
    • Bourgeois S, Harvey R, Fattal E (2005) Polymer colon drug delivery systems and their application to peptides, proteins, and nucleic acids. Am J Drug Deliv 3:171-204
    • (2005) Am J Drug Deliv , vol.3 , pp. 171-204
    • Bourgeois, S.1    Harvey, R.2    Fattal, E.3
  • 19
    • 34447099136 scopus 로고    scopus 로고
    • Induction of secretory immunity and memory at mucosal surfaces
    • Brandtzaeg P (2007) Induction of secretory immunity and memory at mucosal surfaces. Vaccine 25:5467-5484
    • (2007) Vaccine , vol.25 , pp. 5467-5484
    • Brandtzaeg, P.1
  • 21
    • 0034822710 scopus 로고    scopus 로고
    • Oral vaccination in man using antigens in particles: Current status
    • Brayden DJ (2001) Oral vaccination in man using antigens in particles: current status. Eur J Pharm Sci 14:183-189
    • (2001) Eur J Pharm Sci , vol.14 , pp. 183-189
    • Brayden, D.J.1
  • 22
    • 0034806367 scopus 로고    scopus 로고
    • Microparticle vaccine approaches to stimulate mucosal immunisation
    • Brayden DJ, Baird AW (2001) Microparticle vaccine approaches to stimulate mucosal immunisation. Microbes Infect 3:867-876
    • (2001) Microbes Infect , vol.3 , pp. 867-876
    • Brayden, D.J.1    Baird, A.W.2
  • 23
    • 25144503019 scopus 로고    scopus 로고
    • Keynote review: Intestinal Peyer's patch M cells and oral vaccine targeting
    • Brayden DJ, Jepson MA, Baird AW (2005) Keynote review: intestinal Peyer's patch M cells and oral vaccine targeting. Drug Discov Today 10:1145-1157
    • (2005) Drug Discov Today , vol.10 , pp. 1145-1157
    • Brayden, D.J.1    Jepson, M.A.2    Baird, A.W.3
  • 24
    • 0022640190 scopus 로고
    • The absorption of piretanide from the gastrointestinal tract is site-dependent
    • Brockmeier D, Grigoleit HG, Leonhardt H (1986) The absorption of piretanide from the gastrointestinal tract is site-dependent. Eur J Clin Pharmacol 30:79-82
    • (1986) Eur J Clin Pharmacol , vol.30 , pp. 79-82
    • Brockmeier, D.1    Grigoleit, H.G.2    Leonhardt, H.3
  • 25
    • 0026574779 scopus 로고
    • Hydrogels for site-specific drug delivery to the colon: In vitro and in vivo degradation
    • Brondsted H, Kopecek J (1992) Hydrogels for site-specific drug delivery to the colon: in vitro and in vivo degradation. Pharm Res 9:1540-1545
    • (1992) Pharm Res , vol.9 , pp. 1540-1545
    • Brondsted, H.1    Kopecek, J.2
  • 26
    • 0025268994 scopus 로고
    • Effect of coffee on distal colon function
    • Brown SR, Cann PA, Read NW (1990) Effect of coffee on distal colon function. Gut 31:450-453
    • (1990) Gut , vol.31 , pp. 450-453
    • Brown, S.R.1    Cann, P.A.2    Read, N.W.3
  • 27
    • 0002642747 scopus 로고
    • Theorie der Reaktionsgeschwindigkeit in heterogenen Systemen
    • Brunner E (1904) Theorie der Reaktionsgeschwindigkeit in heterogenen Systemen. Z Phys Chem 47:56-102
    • (1904) Z Phys Chem , vol.47 , pp. 56-102
    • Brunner, E.1
  • 29
    • 0041319387 scopus 로고    scopus 로고
    • Gastroretention-a means to address regional variability in intestinal drug absorption
    • Chawla G, Gupta P, Koradia V, Bansal AK (2003) Gastroretention - a means to address regional variability in intestinal drug absorption. Pharm Technol 27:50-68
    • (2003) Pharm Technol , vol.27 , pp. 50-68
    • Chawla, G.1    Gupta, P.2    Koradia, V.3    Bansal, A.K.4
  • 30
    • 1842739438 scopus 로고    scopus 로고
    • A novel pH-sensitive hydrogel composed of N,O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery
    • Chen SC, Wu YC, Mi FL, Lin YH, Yu LC, Sung HW (2004) A novel pH-sensitive hydrogel composed of N,O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery. J Control Release 96:285-300
    • (2004) J Control Release , vol.96 , pp. 285-300
    • Chen, S.C.1    Wu, Y.C.2    Mi, F.L.3    Lin, Y.H.4    Yu, L.C.5    Sung, H.W.6
  • 31
    • 0037151556 scopus 로고    scopus 로고
    • Preparation of cyclosporine A nanoparticles by evaporative precipitation into aqueous solution
    • Chen X, Young TJ, Sarkari M, Williams III RO, Johnston KP (2002) Preparation of cyclosporine A nanoparticles by evaporative precipitation into aqueous solution. Int J Pharm 242:3-14
    • (2002) Int J Pharm , vol.242 , pp. 3-14
    • Chen, X.1    Young, T.J.2    Sarkari, M.3    Williams III, R.O.4    Johnston, K.P.5
  • 32
    • 0032903666 scopus 로고    scopus 로고
    • Synthesis and characterization of pH-sensitive dextran hydrogels as a potential colon-specific drug delivery system
    • Chiu HC, Hsiue GH, Lee YP, Huang LW (1999) Synthesis and characterization of pH-sensitive dextran hydrogels as a potential colon-specific drug delivery system. J Biomater Sci Polym Ed 10:591-608
    • (1999) J Biomater Sci Polym Ed , vol.10 , pp. 591-608
    • Chiu, H.C.1    Hsiue, G.H.2    Lee, Y.P.3    Huang, L.W.4
  • 33
    • 1842538730 scopus 로고    scopus 로고
    • Polysaccharides for colon targeted drug delivery
    • Chourasia MK, Jain SK (2004) Polysaccharides for colon targeted drug delivery. Drug Deliv 11:129-148
    • (2004) Drug Deliv , vol.11 , pp. 129-148
    • Chourasia, M.K.1    Jain, S.K.2
  • 34
    • 0031913037 scopus 로고    scopus 로고
    • M-cell surface beta 1 integrin expression and invasinmediated targeting of Yersinia pseudotuberculosis to mouse Peyer's patch M cells
    • Clark MA, Hirst BH, Jepson MA (1998) M-cell surface beta 1 integrin expression and invasinmediated targeting of Yersinia pseudotuberculosis to mouse Peyer's patch M cells. Infect Immun 66:1237-1243
    • (1998) Infect Immun , vol.66 , pp. 1237-1243
    • Clark, M.A.1    Hirst, B.H.2    Jepson, M.A.3
  • 36
    • 33750517755 scopus 로고    scopus 로고
    • Clinical spectrum of the osmotic-controlled release oral delivery system (OROS), an advanced oral delivery form
    • Conley R, Gupta SL, Sathyan G (2006) Clinical spectrum of the osmotic-controlled release oral delivery system (OROS), an advanced oral delivery form. Curr Med Res Opin 22:1879-1892
    • (2006) Curr Med Res Opin , vol.22 , pp. 1879-1892
    • Conley, R.1    Gupta, S.L.2    Sathyan, G.3
  • 37
    • 0030028851 scopus 로고    scopus 로고
    • Water-in-oil microemulsions containing medium-chain fatty acids/salts: Formulation and intestinal absorption enhancement evaluation
    • Constantinides PP, Welzel G, Smith EH, PL SS, Yiv SH, Owen AB (1996) Water-in-oil microemulsions containing medium-chain fatty acids/salts: formulation and intestinal absorption enhancement evaluation. Pharm Res 13:210-215
    • (1996) Pharm Res , vol.13 , pp. 210-215
    • Constantinides, P.P.1    Welzel, G.2    Smith, E.H.3    Pl, S.S.4    Yiv, S.H.5    Owen, A.B.6
  • 38
    • 0023629560 scopus 로고
    • Bioavailability of L-dopa after Madopar HBS administration in healthy volunteers
    • Crevoisier C, Hoevels B, Zurcher G, Da Prada M (1987) Bioavailability of L-dopa after Madopar HBS administration in healthy volunteers. Eur Neurol 27:36-46
    • (1987) Eur Neurol , vol.27 , pp. 36-46
    • Crevoisier, C.1    Hoevels, B.2    Zurcher, G.3    Da Prada, M.4
  • 39
    • 10444279209 scopus 로고    scopus 로고
    • Cyclodextrin-based pharmaceutics: Past, present and future
    • Davis ME, Brewster ME (2004) Cyclodextrin-based pharmaceutics: past, present and future. Nat Rev Drug Discov 3:1023-1035
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 1023-1035
    • Davis, M.E.1    Brewster, M.E.2
  • 40
    • 0023143517 scopus 로고
    • The gastrointestinal transit of a controlled release pellet formulation of tiaprofenic acid
    • Davis SS, Khosla R, Wilson CG, Washington N (1987) The gastrointestinal transit of a controlled release pellet formulation of tiaprofenic acid. Int J Pharm 34:253-258
    • (1987) Int J Pharm , vol.34 , pp. 253-258
    • Davis, S.S.1    Khosla, R.2    Wilson, C.G.3    Washington, N.4
  • 41
    • 0017882351 scopus 로고
    • Capacity of the human colon to absorb fluid
    • Debongie JC, Philips SF (1978) Capacity of the human colon to absorb fluid. Gastroenterology 74:698-703
    • (1978) Gastroenterology , vol.74 , pp. 698-703
    • Debongie, J.C.1    Philips, S.F.2
  • 42
    • 15544362279 scopus 로고    scopus 로고
    • Polymeric particulates to improve oral bioavailability of peptide drugs
    • Delie F, Blanco-Prieto MJ (2005) Polymeric particulates to improve oral bioavailability of peptide drugs. Molecules 10:65-80
    • (2005) Molecules , vol.10 , pp. 65-80
    • Delie, F.1    Blanco-Prieto, M.J.2
  • 44
    • 33751253462 scopus 로고    scopus 로고
    • Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach
    • des Rieux A, Fievez V, Garinot M, Schneider Y-J, Préat V (2006) Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach. J Control Release 116:1-27
    • (2006) J Control Release , vol.116 , pp. 1-27
    • Des Rieux, A.1    Fievez, V.2    Garinot, M.3    Schneider, Y.-J.4    Préat, V.5
  • 45
    • 0022966980 scopus 로고
    • Comparison of canine and human gastrointestinal physiology
    • Dressman JB (1986) Comparison of canine and human gastrointestinal physiology. Pharm Res 3:123-131
    • (1986) Pharm Res , vol.3 , pp. 123-131
    • Dressman, J.B.1
  • 47
    • 0031563889 scopus 로고    scopus 로고
    • Physiology of the colorectal barrier
    • Edwards C (1997) Physiology of the colorectal barrier. Adv Drug Deliv Rev 28:173-190
    • (1997) Adv Drug Deliv Rev , vol.28 , pp. 173-190
    • Edwards, C.1
  • 49
    • 0023693299 scopus 로고
    • Measurement of gastrointestinal pH profiles in normal, ambulant human subjects
    • Evans DF, Pye G, Bramley R, Clark AG, Dyson TJ, Hardcastle JD (1988) Measurement of gastrointestinal pH profiles in normal, ambulant human subjects. Gut 29:1035-1041
    • (1988) Gut , vol.29 , pp. 1035-1041
    • Evans, D.F.1    Pye, G.2    Bramley, R.3    Clark, A.G.4    Dyson, T.J.5    Hardcastle, J.D.6
  • 50
    • 0030938926 scopus 로고    scopus 로고
    • Modulation of intestinal tight junctions by zonula occludens toxin permits enteral administration of insulin and other macromolecules in an animal model
    • Fasano A, Uzzau S (1997) Modulation of intestinal tight junctions by zonula occludens toxin permits enteral administration of insulin and other macromolecules in an animal model. J Clin Invest 99:1158-1164
    • (1997) J Clin Invest , vol.99 , pp. 1158-1164
    • Fasano, A.1    Uzzau, S.2
  • 51
    • 8844263105 scopus 로고    scopus 로고
    • Targeted delivery, safety, and efficacy of oral enteric-coated formulations of budesonide
    • Fedorak RN, Bistritz L (2005) Targeted delivery, safety, and efficacy of oral enteric-coated formulations of budesonide. Adv Drug Deliv Rev 57:303-316
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 303-316
    • Fedorak, R.N.1    Bistritz, L.2
  • 52
    • 0025787018 scopus 로고
    • Fasting gastric pH and its relationship to true hypochlorhydria in humans
    • Feldman M, Barnett C (1991) Fasting gastric pH and its relationship to true hypochlorhydria in humans. Dig Dis Sci 36:866-869
    • (1991) Dig Dis Sci , vol.36 , pp. 866-869
    • Feldman, M.1    Barnett, C.2
  • 53
    • 44949228208 scopus 로고    scopus 로고
    • Fluorescent bio-nanoprobes to characterise cytoadhesion and cytoinvasion
    • Fillafer C, Friedl DS, Wirth M, Gabor F (2008) Fluorescent bio-nanoprobes to characterise cytoadhesion and cytoinvasion. Small 4:627-633
    • (2008) Small , vol.4 , pp. 627-633
    • Fillafer, C.1    Friedl, D.S.2    Wirth, M.3    Gabor, F.4
  • 54
    • 0030993565 scopus 로고    scopus 로고
    • The oral absorption of micro- and nanoparticulates: Neither exceptional nor unusual
    • Florence AT (1997) The oral absorption of micro- and nanoparticulates: neither exceptional nor unusual. Pharm Res 14:259-266
    • (1997) Pharm Res , vol.14 , pp. 259-266
    • Florence, A.T.1
  • 55
    • 21744458087 scopus 로고    scopus 로고
    • Nanoparticle uptake by the oral route: Fulfilling its potential?
    • Florence AT (2005) Nanoparticle uptake by the oral route: Fulfilling its potential? Drug Discov Today Technol 2:75-81
    • (2005) Drug Discov Today Technol , vol.2 , pp. 75-81
    • Florence, A.T.1
  • 56
    • 84967350845 scopus 로고    scopus 로고
    • Nanoparticle flow: Implications for drug delivery
    • Torchilin VP (ed), Imperial College Press, London
    • Florence AT (2006) Nanoparticle flow: implications for drug delivery. In: Torchilin VP (ed) Nanoparticles as drug carriers. Imperial College Press, London, pp 9-27
    • (2006) Nanoparticles As Drug Carriers , pp. 9-27
    • Florence, A.T.1
  • 58
    • 9244247602 scopus 로고    scopus 로고
    • Exploiting receptor biology for oral vaccination with biodegradable particulates
    • Foster N, Hirst BH (2005) Exploiting receptor biology for oral vaccination with biodegradable particulates. Adv Drug Deliv Rev 57:431-450
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 431-450
    • Foster, N.1    Hirst, B.H.2
  • 59
    • 35349004783 scopus 로고    scopus 로고
    • Optimization of oral immunization through receptormediated targeting of M cells
    • Foxwell AR, Cripps AW, Kyd JM (2007) Optimization of oral immunization through receptormediated targeting of M cells. Hum Vaccin 3:220-223
    • (2007) Hum Vaccin , vol.3 , pp. 220-223
    • Foxwell, A.R.1    Cripps, A.W.2    Kyd, J.M.3
  • 60
    • 8844286917 scopus 로고    scopus 로고
    • New oral delivery systems for treatment of inflammatory bowel disease
    • Friend DR (2005) New oral delivery systems for treatment of inflammatory bowel disease. Adv Drug Deliv Rev 57:247-265
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 247-265
    • Friend, D.R.1
  • 61
    • 0021354414 scopus 로고
    • A colon-specific drug-delivery system based on drug glycosides and the glycosidases of colonic bacteria
    • Friend DR, Chang GW (1984) A colon-specific drug-delivery system based on drug glycosides and the glycosidases of colonic bacteria. J Med Chem 27:261-266
    • (1984) J Med Chem , vol.27 , pp. 261-266
    • Friend, D.R.1    Chang, G.W.2
  • 62
    • 0034079042 scopus 로고    scopus 로고
    • Biological information transfer beyond the genetic code: The sugar code
    • Gabius HJ (2000) Biological information transfer beyond the genetic code: the sugar code. Naturwissenschaften 87:108-121
    • (2000) Naturwissenschaften , vol.87 , pp. 108-121
    • Gabius, H.J.1
  • 63
    • 1142273201 scopus 로고    scopus 로고
    • The lectin-cell interaction and its implications to intestinal lectin-mediated drug delivery
    • Gabor F, Bogner E, Weissenböck A, Wirth M (2004) The lectin-cell interaction and its implications to intestinal lectin-mediated drug delivery. Adv Drug Deliv Rev 56:459-480
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 459-480
    • Gabor, F.1    Bogner, E.2    Weissenböck, A.3    Wirth, M.4
  • 64
    • 33645276807 scopus 로고    scopus 로고
    • Experimental determination of the diffusion boundary layer width of micron and submicron particles
    • Galli C (2006) Experimental determination of the diffusion boundary layer width of micron and submicron particles. Int J Pharm 313:114-122
    • (2006) Int J Pharm , vol.313 , pp. 114-122
    • Galli, C.1
  • 65
    • 0029762114 scopus 로고    scopus 로고
    • Standardization of clinical criteria required for use of the 12.5mm barium tablet in evaluating esophageal lumenal patency
    • Gallo SH, McClave SA, Makk LJK, Looney SW (1996) Standardization of clinical criteria required for use of the 12.5mm barium tablet in evaluating esophageal lumenal patency. Gastrointest Endosc 44:181-184
    • (1996) Gastrointest Endosc , vol.44 , pp. 181-184
    • Gallo, S.H.1    McClave, S.A.2    Makk, L.J.K.3    Looney, S.W.4
  • 67
    • 0028122960 scopus 로고
    • Oral chronotopic1 drug delivery systems: Achievement of time and/or site specificity
    • Gazzaniga A, Sangalli ME, Giordano F (1994) Oral chronotopic1 drug delivery systems: achievement of time and/or site specificity. Eur J Pharm Biopharm 40:246-250
    • (1994) Eur J Pharm Biopharm , vol.40 , pp. 246-250
    • Gazzaniga, A.1    Sangalli, M.E.2    Giordano, F.3
  • 68
    • 32044432092 scopus 로고    scopus 로고
    • Studies on the cross-linking of poly (vinyl alcohol)
    • Gohil JM, Bhattacharya A, Ray P (2006) Studies on the cross-linking of poly (vinyl alcohol). J Polym Res 13:161-169
    • (2006) J Polym Res , vol.13 , pp. 161-169
    • Gohil, J.M.1    Bhattacharya, A.2    Ray, P.3
  • 69
    • 21844459973 scopus 로고    scopus 로고
    • 2-Hydroxypropyl-b-cyclodextrin (HP-b-CD): A toxicology review
    • Gould S, Scott RC (2005) 2-Hydroxypropyl-b-cyclodextrin (HP-b-CD): a toxicology review. Food Chem Toxicol 43:1451-1459
    • (2005) Food Chem Toxicol , vol.43 , pp. 1451-1459
    • Gould, S.1    Scott, R.C.2
  • 70
    • 0035253518 scopus 로고    scopus 로고
    • A novel pH- and time-based multi-unit potential colonic drug delivery system
    • Gupta VS, Beckert TE, Price JC (2001) A novel pH- and time-based multi-unit potential colonic drug delivery system. Int J Pharm 213:83-91
    • (2001) Int J Pharm , vol.213 , pp. 83-91
    • Gupta, V.S.1    Beckert, T.E.2    Price, J.C.3
  • 72
    • 0025309060 scopus 로고
    • Ciprofloxacin absorption in different regions of the human gastrointestinal tract. Investigations with hf-capsule
    • Harder S, Fuhr U, Beermann D, Staib AH (1990) Ciprofloxacin absorption in different regions of the human gastrointestinal tract. Investigations with hf-capsule. Br J Clin Pharmacol 30:35-39
    • (1990) Br J Clin Pharmacol , vol.30 , pp. 35-39
    • Harder, S.1    Fuhr, U.2    Beermann, D.3    Staib, A.H.4
  • 73
    • 0023182144 scopus 로고
    • Evaluation of an enteric-coated naproxen tablet using gamma scintigraphy and pH monitoring
    • Hardy JG, Evans DF, Zaki I, Clark AG, Tonnesen HH, Gamst ON (1987) Evaluation of an enteric-coated naproxen tablet using gamma scintigraphy and pH monitoring. Int J Pharm 37:245-250
    • (1987) Int J Pharm , vol.37 , pp. 245-250
    • Hardy, J.G.1    Evans, D.F.2    Zaki, I.3    Clark, A.G.4    Tonnesen, H.H.5    Gamst, O.N.6
  • 76
    • 0030469774 scopus 로고    scopus 로고
    • Current applications of polysaccharides in colon targeting
    • Havgaard L, Brondsted H (1996) Current applications of polysaccharides in colon targeting. Crit Rev Ther Dug Carrier Syst 13:185-223
    • (1996) Crit Rev Ther Dug Carrier Syst , vol.13 , pp. 185-223
    • Havgaard, L.1    Brondsted, H.2
  • 77
    • 0037472115 scopus 로고    scopus 로고
    • Chitosan-based gastrointestinal delivery systems
    • Hejazi R, Amiji M (2003) Chitosan-based gastrointestinal delivery systems. J Control Release 89:151-165
    • (2003) J Control Release , vol.89 , pp. 151-165
    • Hejazi, R.1    Amiji, M.2
  • 79
    • 0025201769 scopus 로고
    • Effect of incorporating fat into a liquid test meal on the relation between intragastric distribution and gastric emptying in human volunteers
    • Houghton LA, Mangnall YF, Read NW (1990) Effect of incorporating fat into a liquid test meal on the relation between intragastric distribution and gastric emptying in human volunteers. Gut 31:1226-1229
    • (1990) Gut , vol.31 , pp. 1226-1229
    • Houghton, L.A.1    Mangnall, Y.F.2    Read, N.W.3
  • 80
    • 0242334090 scopus 로고    scopus 로고
    • Spray freezing into liquid (SFL) particle engineering technology to enhance dissolution of poorly water soluble drugs: Organic solvent versus organic/aqueous co-solvent systems
    • Hu J, Johnston KP, Williams RO (2003) Spray freezing into liquid (SFL) particle engineering technology to enhance dissolution of poorly water soluble drugs: organic solvent versus organic/aqueous co-solvent systems. Eur J Pharm Sci 20:295-303
    • (2003) Eur J Pharm Sci , vol.20 , pp. 295-303
    • Hu, J.1    Johnston, K.P.2    Williams, R.O.3
  • 81
    • 0024215976 scopus 로고
    • Passive and carrier mediated intestinal absorption components of captopril
    • Hu M, Amidon GL (1988) Passive and carrier mediated intestinal absorption components of captopril. J Pharm Sci 77:1007-1011
    • (1988) J Pharm Sci , vol.77 , pp. 1007-1011
    • Hu, M.1    Amidon, G.L.2
  • 82
    • 0036771081 scopus 로고    scopus 로고
    • A comparison of commonly used polyethoxylated pharmaceutical excipients on their ability to inhibit P-glycoprotein activity in vitro
    • Hugger ED, Novak BL, Burton PS, Audus KL, Borchardt RT (2002) A comparison of commonly used polyethoxylated pharmaceutical excipients on their ability to inhibit P-glycoprotein activity in vitro. J Pharm Sci 91:1991-2002
    • (2002) J Pharm Sci , vol.91 , pp. 1991-2002
    • Hugger, E.D.1    Novak, B.L.2    Burton, P.S.3    Audus, K.L.4    Borchardt, R.T.5
  • 83
    • 77953654414 scopus 로고    scopus 로고
    • Tablet-splitting games are bad patient care ... and bad pharmacy practice
    • Hussar DA (2000) Tablet-splitting games are bad patient care ... and bad pharmacy practice. Pharm Today 6:5
    • (2000) Pharm Today , vol.6 , pp. 5
    • Hussar, D.A.1
  • 85
    • 0025751561 scopus 로고
    • A new multiple-unit oral floating dosage system. I: Preparation and in vitro evaluation of floating and sustained-release characteristics
    • Ichikawa M, Watanabe S, Miyake Y (1991) A new multiple-unit oral floating dosage system. I: preparation and in vitro evaluation of floating and sustained-release characteristics. J Pharm Sci 80:1062-1066
    • (1991) J Pharm Sci , vol.80 , pp. 1062-1066
    • Ichikawa, M.1    Watanabe, S.2    Miyake, Y.3
  • 86
    • 0025674686 scopus 로고
    • Nanoparticle uptake by the rat gastrointestinal mucosa: Quantitation and particle size dependency
    • Jani P, Halbert GW, Langridge J, Florence AT (1990) Nanoparticle uptake by the rat gastrointestinal mucosa: quantitation and particle size dependency. J Pharm Pharmacol 42:821-826
    • (1990) J Pharm Pharmacol , vol.42 , pp. 821-826
    • Jani, P.1    Halbert, G.W.2    Langridge, J.3    Florence, A.T.4
  • 87
    • 0026730479 scopus 로고
    • Further histological evidence of the gastrointestinal absorption of polystyrene nanospheres in the rat
    • Jani PU, Florence AT, McCarthy DE (1992) Further histological evidence of the gastrointestinal absorption of polystyrene nanospheres in the rat. Int J Pharm 84:245-252
    • (1992) Int J Pharm , vol.84 , pp. 245-252
    • Jani, P.U.1    Florence, A.T.2    McCarthy, D.E.3
  • 88
    • 0022395318 scopus 로고
    • Investigation of drug absorption from the gastrointestinal tract of man. I. Metoprolol in the stomach, duodenum and jejunum
    • Jobin G, Cortot A, Godbillon I, Duval M, Schoeller JP, Hirtz J, Bernier JJ (1985) Investigation of drug absorption from the gastrointestinal tract of man. I. Metoprolol in the stomach, duodenum and jejunum. Br J Clin Pharmacol 19:975-1055
    • (1985) Br J Clin Pharmacol , vol.19 , pp. 975-1055
    • Jobin, G.1    Cortot, A.2    Godbillon, I.3    Duval, M.4    Schoeller, J.P.5    Hirtz, J.6    Bernier, J.J.7
  • 91
    • 28444461830 scopus 로고    scopus 로고
    • Drug nanocrystals of poorly soluble drugs produced by high pressure homogenisation
    • Keck CM, Müller RH (2006) Drug nanocrystals of poorly soluble drugs produced by high pressure homogenisation. Eur J Pharm Biopharm 62:3-16
    • (2006) Eur J Pharm Biopharm , vol.62 , pp. 3-16
    • Keck, C.M.1    Müller, R.H.2
  • 92
    • 34548049483 scopus 로고    scopus 로고
    • Nanosizing-oral formulation development and biopharmaceutical evaluation
    • Kesisoglou F, Panmai S, Wu Y (2007) Nanosizing - oral formulation development and biopharmaceutical evaluation. Adv Drug Deliv Rev 59:631-644
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 631-644
    • Kesisoglou, F.1    Panmai, S.2    Wu, Y.3
  • 93
    • 0032910069 scopus 로고    scopus 로고
    • Characterization of tolbutamide polymorphs (Burger's forms II and IV) and polymorphic transition behavior
    • Kimura K, Hirayama F, Uekama K (1999) Characterization of tolbutamide polymorphs (Burger's forms II and IV) and polymorphic transition behavior. Int J Pharm 88:385-391
    • (1999) Int J Pharm , vol.88 , pp. 385-391
    • Kimura, K.1    Hirayama, F.2    Uekama, K.3
  • 94
    • 4444221676 scopus 로고    scopus 로고
    • From structure to disease: The evolving tale of aquaporin biology
    • King LS, Lozono D, Agre P (2004) From structure to disease: the evolving tale of aquaporin biology. Nat Rev Mol Cell Biol 5:687-698
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 687-698
    • King, L.S.1    Lozono, D.2    Agre, P.3
  • 95
    • 0016131378 scopus 로고
    • Gastrointestinal transit estimated by an isotope capsule
    • Kirwan WO, Smith AN (1974) Gastrointestinal transit estimated by an isotope capsule. Scand J Gastroenterol 9:763-766
    • (1974) Scand J Gastroenterol , vol.9 , pp. 763-766
    • Kirwan, W.O.1    Smith, A.N.2
  • 97
    • 0035287318 scopus 로고    scopus 로고
    • Delivery systems for penetration enhancement of peptide and protein drugs: Design considerations
    • Kompella UB, Lee VHL (2001) Delivery systems for penetration enhancement of peptide and protein drugs: design considerations. Adv Drug Deliv Rev 46:211-245
    • (2001) Adv Drug Deliv Rev , vol.46 , pp. 211-245
    • Kompella, U.B.1    Lee, V.H.L.2
  • 98
    • 0033982671 scopus 로고    scopus 로고
    • Heavy metal contamination of nanosuspensions produced by high-pressure homogenisation
    • Krause KP, Kayser O, Mäder K, Gust R, Müller RH (2000) Heavy metal contamination of nanosuspensions produced by high-pressure homogenisation. Int J Pharm 196:169-172
    • (2000) Int J Pharm , vol.196 , pp. 169-172
    • Krause, K.P.1    Kayser, O.2    Mäder, K.3    Gust, R.4    Müller, R.H.5
  • 99
    • 34248658271 scopus 로고    scopus 로고
    • Development of pH-and time-dependent oral microparticles to optimize budesonide delivery to ileum and colon
    • Krishnamachari Y, Madan P, Lin S (2007) Development of pH- and time-dependent oral microparticles to optimize budesonide delivery to ileum and colon. Int J Pharm 338:238-247
    • (2007) Int J Pharm , vol.338 , pp. 238-247
    • Krishnamachari, Y.1    Madan, P.2    Lin, S.3
  • 100
    • 0034182386 scopus 로고    scopus 로고
    • Nano and microparticles as controlled drug delivery devices
    • Kumar RMN (2000) Nano and microparticles as controlled drug delivery devices. J Pharm Pharm Sci 3:234-258
    • (2000) J Pharm Pharm Sci , vol.3 , pp. 234-258
    • Kumar, R.M.N.1
  • 101
    • 0034872426 scopus 로고    scopus 로고
    • Size-dependent bioadhesion of micro-and nanoparticulate carriers to the inflamed colonic mucosa
    • Lamprecht A, Schaefer U, Lehr CM (2001) Size-dependent bioadhesion of micro- and nanoparticulate carriers to the inflamed colonic mucosa. Pharm Res 18:788-793
    • (2001) Pharm Res , vol.18 , pp. 788-793
    • Lamprecht, A.1    Schaefer, U.2    Lehr, C.M.3
  • 103
    • 0025847154 scopus 로고
    • Stability of ketoprofen-dextran ester prodrugs in homogeneates of various segments of the pig GI tract
    • Larsen C, Jensen BH, Olesen HP (1991) Stability of ketoprofen-dextran ester prodrugs in homogeneates of various segments of the pig GI tract. Acta Pharm Nord 3:41-44
    • (1991) Acta Pharm Nord , vol.3 , pp. 41-44
    • Larsen, C.1    Jensen, B.H.2    Olesen, H.P.3
  • 104
    • 14744272833 scopus 로고    scopus 로고
    • The use of biopharmaceutic classification of drugs in drug discovery and development: Current stauts and future extension
    • Lennernäs H, Abrahamsson B (2005) The use of biopharmaceutic classification of drugs in drug discovery and development: current stauts and future extension. J Pharm Pharmacol 57:273-285
    • (2005) J Pharm Pharmacol , vol.57 , pp. 273-285
    • Lennernäs, H.1    Abrahamsson, B.2
  • 105
    • 0037235939 scopus 로고    scopus 로고
    • Can needle-free administration of vaccines become the norm in global immunization?
    • Levine MM (2003) Can needle-free administration of vaccines become the norm in global immunization? Nat Med 9:99-103
    • (2003) Nat Med , vol.9 , pp. 99-103
    • Levine, M.M.1
  • 106
    • 33751195735 scopus 로고    scopus 로고
    • Hydrogels in controlled release formulations: Network design and mathematical modeling
    • Lin CC, Metters AT (2006) Hydrogels in controlled release formulations: network design and mathematical modeling. Adv Drug Deliv Rev 58:1379-1408
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 1379-1408
    • Lin, C.C.1    Metters, A.T.2
  • 107
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski CA, Lombardo F, Dominy BW, Feeney PJ (2001) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev 46:3-26
    • (2001) Adv Drug Deliv Rev , vol.46 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 108
    • 0023920913 scopus 로고
    • Longterm effects of fermentable fibres on rat colonic pH and epithelial cell cycle
    • Lipton JR, Coder DM, Jacobs LR (1988) Longterm effects of fermentable fibres on rat colonic pH and epithelial cell cycle. J Nutr 118:840-845
    • (1988) J Nutr , vol.118 , pp. 840-845
    • Lipton, J.R.1    Coder, D.M.2    Jacobs, L.R.3
  • 109
    • 0034632940 scopus 로고    scopus 로고
    • Nifedipine controlled delivery by sandwiched osmotic tablet system
    • Liu L, Ku J, Khang G, Lee B, Rhee JM, Lee HB (2000) Nifedipine controlled delivery by sandwiched osmotic tablet system. J Control Release 68:145-156
    • (2000) J Control Release , vol.68 , pp. 145-156
    • Liu, L.1    Ku, J.2    Khang, G.3    Lee, B.4    Rhee, J.M.5    Lee, H.B.6
  • 110
    • 0029080002 scopus 로고
    • Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs
    • Liversidge GG, Cundy KC (1995) Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs. Int J Pharm 125:91-97
    • (1995) Int J Pharm , vol.125 , pp. 91-97
    • Liversidge, G.G.1    Cundy, K.C.2
  • 111
    • 0242584996 scopus 로고    scopus 로고
    • Wheat germ agglutinin binds to the epidermal growth factor-receptor of artificial Caco-2 membranes as detected by silver nanoparticle enhanced fluorescence
    • Lochner N, Pittner F, Wirth M, Gabor F (2003) Wheat germ agglutinin binds to the epidermal growth factor-receptor of artificial Caco-2 membranes as detected by silver nanoparticle enhanced fluorescence. Pharm Res 20:833-839
    • (2003) Pharm Res , vol.20 , pp. 833-839
    • Lochner, N.1    Pittner, F.2    Wirth, M.3    Gabor, F.4
  • 113
    • 0022623781 scopus 로고
    • Comparison of gastrointestinal pH in dogs and humans: Implications of the use of the beagle dog as a model for oral absorption in humans
    • Lui CY, Amidon GL, Berardi RR (1986) Comparison of gastrointestinal pH in dogs and humans: implications of the use of the beagle dog as a model for oral absorption in humans. J Pharm Sci 75:271-274
    • (1986) J Pharm Sci , vol.75 , pp. 271-274
    • Lui, C.Y.1    Amidon, G.L.2    Berardi, R.R.3
  • 114
    • 0031563894 scopus 로고    scopus 로고
    • Peptide drug delivery: Colonic and rectal absorption
    • Mackay M, Phillips J, Hastewell J (1997) Peptide drug delivery: colonic and rectal absorption. Adv Drug Deliv Rev 28:253-273
    • (1997) Adv Drug Deliv Rev , vol.28 , pp. 253-273
    • MacKay, M.1    Phillips, J.2    Hastewell, J.3
  • 116
    • 0023219622 scopus 로고
    • Mucosal surface pH of the large intestine of the rat and of normal and inflamed large intestine in man
    • McNeil NI, Ling KLE, Wager J (1987) Mucosal surface pH of the large intestine of the rat and of normal and inflamed large intestine in man. Gut 28:707-713
    • (1987) Gut , vol.28 , pp. 707-713
    • McNeil, N.I.1    Ling, K.L.E.2    Wager, J.3
  • 117
    • 0018145632 scopus 로고
    • Influence of food on the bioavailability of drugs
    • Melander A (1987) Influence of food on the bioavailability of drugs. Clin Pharmacokinet 3:337-341
    • (1987) Clin Pharmacokinet , vol.3 , pp. 337-341
    • Melander, A.1
  • 118
    • 0037312695 scopus 로고    scopus 로고
    • Nanosizing: A formulation approach for poorly-water-soluble compounds
    • Merisko-Liversidge E, Liversidge GG, Cooper ER (2003) Nanosizing: a formulation approach for poorly-water-soluble compounds. Eur J Pharm Sci 18:113-120
    • (2003) Eur J Pharm Sci , vol.18 , pp. 113-120
    • Merisko-Liversidge, E.1    Liversidge, G.G.2    Cooper, E.R.3
  • 122
    • 0031807470 scopus 로고    scopus 로고
    • Colon-specific drug delivery based on a cyclodextrin prodrug: Release behaviour of biphenylylacetic acid from its cyclodextrin conjugates in rat intestinal tracts after oral administration
    • Minami K, Hirayama F, Uekama K (1998) Colon-specific drug delivery based on a cyclodextrin prodrug: release behaviour of biphenylylacetic acid from its cyclodextrin conjugates in rat intestinal tracts after oral administration. J Pharm Sci 87:715-720
    • (1998) J Pharm Sci , vol.87 , pp. 715-720
    • Minami, K.1    Hirayama, F.2    Uekama, K.3
  • 123
    • 1142273203 scopus 로고    scopus 로고
    • Drug targeting to the colon with lectins and neoglycoconjugates
    • Minko T (2004) Drug targeting to the colon with lectins and neoglycoconjugates. Adv Drug Deliv Rev 56:491-509
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 491-509
    • Minko, T.1
  • 124
    • 85055809757 scopus 로고    scopus 로고
    • Drug nanocrystals-the universal formulation approach for poorly soluble drugs
    • Thassu D, Deleers M, Pathak Y (eds), Informa Healthcare, New York
    • Möschwitzer J, Müller RH (2007) Drug nanocrystals - the universal formulation approach for poorly soluble drugs. In: Thassu D, Deleers M, Pathak Y (eds) Nanoparticulate Drug Delivery Systems. Informa Healthcare, New York, pp 71-88
    • (2007) Nanoparticulate Drug Delivery Systems , pp. 71-88
    • Möschwitzer, J.1    Müller, R.H.2
  • 125
    • 0034671884 scopus 로고    scopus 로고
    • Potential inhibitory effects of formulation ingredients on intestinal cytochrome P450
    • Mountfield RJ, Senepin S, Schleimer M, Walter I, Bittner B (2000) Potential inhibitory effects of formulation ingredients on intestinal cytochrome P450. Int J Pharm 211:89-92
    • (2000) Int J Pharm , vol.211 , pp. 89-92
    • Mountfield, R.J.1    Senepin, S.2    Schleimer, M.3    Walter, I.4    Bittner, B.5
  • 126
  • 127
    • 0019570321 scopus 로고
    • Effect of fatty acids and monoglycerides on permeability of lipid bilayer
    • Muranushi N, Takagi S, Muranishi S, Sezaki H (1981) Effect of fatty acids and monoglycerides on permeability of lipid bilayer. Chem Phys Lipids 28:269-279
    • (1981) Chem Phys Lipids , vol.28 , pp. 269-279
    • Muranushi, N.1    Takagi, S.2    Muranishi, S.3    Sezaki, H.4
  • 128
    • 0342897023 scopus 로고    scopus 로고
    • Nanosuspensions for the formulation of poorly soluble drugs: I. Preparation by a size-reduction technique
    • Müller RH, Peters K (1998) Nanosuspensions for the formulation of poorly soluble drugs: I. Preparation by a size-reduction technique. Int J Pharm 160:229-237
    • (1998) Int J Pharm , vol.160 , pp. 229-237
    • Müller, R.H.1    Peters, K.2
  • 129
    • 0002642747 scopus 로고
    • Theorie der Reaktionsgeschwindigkeit in heterogenen Systemen
    • Nernst W (1904) Theorie der Reaktionsgeschwindigkeit in heterogenen Systemen. Z Phys Chem 47:52-55
    • (1904) Z Phys Chem , vol.47 , pp. 52-55
    • Nernst, W.1
  • 130
    • 0029875543 scopus 로고    scopus 로고
    • The use of surfactants to enhance the permeability of peptides through caco-2 cells by inhibition of an apically polarized efflux system
    • Nerurkar MM, Burton PS, Borchardt RT (1996) The use of surfactants to enhance the permeability of peptides through caco-2 cells by inhibition of an apically polarized efflux system. Pharm Res 13:528-534
    • (1996) Pharm Res , vol.13 , pp. 528-534
    • Nerurkar, M.M.1    Burton, P.S.2    Borchardt, R.T.3
  • 131
    • 33947487639 scopus 로고
    • The rate of solution of solid substances in their own solutions
    • Noyes AA, Whitney WR (1897) The rate of solution of solid substances in their own solutions. J Am Chem Soc 19:930-934
    • (1897) J Am Chem Soc , vol.19 , pp. 930-934
    • Noyes, A.A.1    Whitney, W.R.2
  • 132
    • 33748795860 scopus 로고    scopus 로고
    • Microparticle-based technologies for vaccines
    • O'Hagan DT, Singh M, Ulmer JB (2006) Microparticle-based technologies for vaccines. Methods 40:10-19
    • (2006) Methods , vol.40 , pp. 10-19
    • O'Hagan, D.T.1    Singh, M.2    Ulmer, J.B.3
  • 133
    • 0842265902 scopus 로고    scopus 로고
    • Evaluation of novel one-step dry-coated tablets as a platform for delayed-release tablets
    • Ozeki Y, Ando M, Watanabe Y, Danjo K (2004) Evaluation of novel one-step dry-coated tablets as a platform for delayed-release tablets. J Control Release 95:51-60
    • (2004) J Control Release , vol.95 , pp. 51-60
    • Ozeki, Y.1    Ando, M.2    Watanabe, Y.3    Danjo, K.4
  • 134
    • 0029983729 scopus 로고    scopus 로고
    • Preparation and characterization of freeze-dried chitosan-poly (ethylene oxide) hydrogels for site-specific antibiotic delivery in the stomach
    • Patel VR, Amiji MM (1996) Preparation and characterization of freeze-dried chitosan-poly (ethylene oxide) hydrogels for site-specific antibiotic delivery in the stomach. Pharm Res 13:588-593
    • (1996) Pharm Res , vol.13 , pp. 588-593
    • Patel, V.R.1    Amiji, M.M.2
  • 136
    • 0025662011 scopus 로고
    • Dynamic and equilibrium swelling behaviour of pH-sensitive hydrogels containing 2-hydroxyethyl methacrylate
    • Peppas LB, Peppas NA (1990) Dynamic and equilibrium swelling behaviour of pH-sensitive hydrogels containing 2-hydroxyethyl methacrylate. Biomaterials 11:635-644
    • (1990) Biomaterials , vol.11 , pp. 635-644
    • Peppas, L.B.1    Peppas, N.A.2
  • 137
    • 0021160552 scopus 로고
    • Sulfasalazine: Pharmacology, clinical use, toxicity, and related new drug development
    • Peppercorn MA (1984) Sulfasalazine: pharmacology, clinical use, toxicity, and related new drug development. Ann Int Med 101:377-386
    • (1984) Ann Int Med , vol.101 , pp. 377-386
    • Peppercorn, M.A.1
  • 139
    • 39149092022 scopus 로고    scopus 로고
    • Enhancing intestinal drug solubilisation using lipid-based delivery systems
    • Porter CJH, Pouton CW, Cuine JF, Charman WN (2008) Enhancing intestinal drug solubilisation using lipid-based delivery systems. Adv Drug Deliv Rev 60:673-691
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 673-691
    • Porter, C.J.H.1    Pouton, C.W.2    Cuine, J.F.3    Charman, W.N.4
  • 140
    • 0035981078 scopus 로고    scopus 로고
    • Environment-sensitive hydrogels for drug delivery
    • Qiu Y, Park K (2001) Environment-sensitive hydrogels for drug delivery. Adv Drug Deliv Rev 53:321-339
    • (2001) Adv Drug Deliv Rev , vol.53 , pp. 321-339
    • Qiu, Y.1    Park, K.2
  • 141
    • 0037467170 scopus 로고    scopus 로고
    • Microcrystals for dissolution rate enhancement of poorly water-soluble drugs
    • Rasenack N, Hartenhauer H, Müller BW (2003) Microcrystals for dissolution rate enhancement of poorly water-soluble drugs. Int J Pharm 254:137-145
    • (2003) Int J Pharm , vol.254 , pp. 137-145
    • Rasenack, N.1    Hartenhauer, H.2    Müller, B.W.3
  • 142
    • 0019203517 scopus 로고
    • Transit of a meal through the stomach, small intestine and colon of normal subjects and its role in the pathogenesis of diarrhea
    • Read NW, Miles CA, Fisher D, Holgate AM, Kime ND, Mitchell MA, Reeve AM, Walker W (1980) Transit of a meal through the stomach, small intestine and colon of normal subjects and its role in the pathogenesis of diarrhea. Gastroenterology 79:1276-1282
    • (1980) Gastroenterology , vol.79 , pp. 1276-1282
    • Read, N.W.1    Miles, C.A.2    Fisher, D.3    Holgate, A.M.4    Kime, N.D.5    Mitchell, M.A.6    Reeve, A.M.7    Walker, W.8
  • 147
    • 0029953050 scopus 로고    scopus 로고
    • Drug absorption sites in the gastrointestinal tract and dosage forms for site-specific delivery
    • Rouge N, Buri P, Doelker E (1996) Drug absorption sites in the gastrointestinal tract and dosage forms for site-specific delivery. Int J Pharm 136:117-139
    • (1996) Int J Pharm , vol.136 , pp. 117-139
    • Rouge, N.1    Buri, P.2    Doelker, E.3
  • 148
    • 0026744322 scopus 로고
    • Chondroitin-sulfate: A potential biodegradable carrier for colon-specific drug delivery
    • Rubinstein A, Nakar D, Sintov A (1992) Chondroitin-sulfate: a potential biodegradable carrier for colon-specific drug delivery. Int J Pharm 84:141-150
    • (1992) Int J Pharm , vol.84 , pp. 141-150
    • Rubinstein, A.1    Nakar, D.2    Sintov, A.3
  • 150
    • 0032586956 scopus 로고    scopus 로고
    • Vitamin B12-mediated transport of nanoparticles across Caco-2 cells
    • Russell-Jones GJ, Arthur L, Walker H (1999) Vitamin B12-mediated transport of nanoparticles across Caco-2 cells. Int J Pharm 179:247-255
    • (1999) Int J Pharm , vol.179 , pp. 247-255
    • Russell-Jones, G.J.1    Arthur, L.2    Walker, H.3
  • 151
    • 33646492929 scopus 로고    scopus 로고
    • Tight junction modulation and its relationship to drug delivery
    • Salama NN, Eddington ND, Fasano A (2006) Tight junction modulation and its relationship to drug delivery. Adv Drug Deliv Rev 58:15-28
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 15-28
    • Salama, N.N.1    Eddington, N.D.2    Fasano, A.3
  • 153
    • 0015757745 scopus 로고
    • Metabolism of foreign compounds by gastrointestinal microorganisms
    • Scheline RR (1973) Metabolism of foreign compounds by gastrointestinal microorganisms. Pharmacol Rev 25:451-523
    • (1973) Pharmacol Rev , vol.25 , pp. 451-523
    • Scheline, R.R.1
  • 155
    • 14544286414 scopus 로고    scopus 로고
    • Particle uptake by Peyer's patches: A pathway for drug and vaccine delivery
    • Shakweh M, Ponchel G, Fattal E (2004) Particle uptake by Peyer's patches: a pathway for drug and vaccine delivery. Expert Opin Drug Deliv 1:141-163
    • (2004) Expert Opin Drug Deliv , vol.1 , pp. 141-163
    • Shakweh, M.1    Ponchel, G.2    Fattal, E.3
  • 156
    • 7244258916 scopus 로고    scopus 로고
    • History of lectins: From hemagglutinins to biological recognition molecules
    • Sharon N, Lis H (2004) History of lectins: from hemagglutinins to biological recognition molecules. Glycobiology 14:53R-62R
    • (2004) Glycobiology , vol.14
    • Sharon, N.1    Lis, H.2
  • 159
    • 0023945604 scopus 로고
    • Evidence for the delivery of narcotic antagonists to the colon as their glucuronide conjugates
    • Simpkins JW, Smulkowski M, Dixon R, Tuttle R (1988) Evidence for the delivery of narcotic antagonists to the colon as their glucuronide conjugates. J Phamacol Exp Ther 244:195-205
    • (1988) J Phamacol Exp Ther , vol.244 , pp. 195-205
    • Simpkins, J.W.1    Smulkowski, M.2    Dixon, R.3    Tuttle, R.4
  • 160
    • 0033991593 scopus 로고    scopus 로고
    • Floating drug delivery systems: An approach to oral controlled drug delivery via gastric retention
    • Singh BN, Kim KH (2000) Floating drug delivery systems: an approach to oral controlled drug delivery via gastric retention. J Control Release 63:235-259
    • (2000) J Control Release , vol.63 , pp. 235-259
    • Singh, B.N.1    Kim, K.H.2
  • 161
    • 0037243915 scopus 로고    scopus 로고
    • Microbially triggered drug delivery to the colon
    • Sinha VR, Kumria R (2003) Microbially triggered drug delivery to the colon. Eur J Pharm Sci 18:3-18
    • (2003) Eur J Pharm Sci , vol.18 , pp. 3-18
    • Sinha, V.R.1    Kumria, R.2
  • 162
  • 163
  • 164
    • 0035498328 scopus 로고    scopus 로고
    • Peroral route: An opportunity for protein and peptide drug delivery
    • Sood A, Panchagnula R (2001) Peroral route: an opportunity for protein and peptide drug delivery. Chem Rev 101:3275-3303
    • (2001) Chem Rev , vol.101 , pp. 3275-3303
    • Sood, A.1    Panchagnula, R.2
  • 166
    • 33748430023 scopus 로고    scopus 로고
    • Drug delivery to the upper small intestine window using gastroretentive technologies
    • Streubel A, Siepmann J, Bodmeier R (2006) Drug delivery to the upper small intestine window using gastroretentive technologies. Curr Opin Pharmacol 6:501-508
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 501-508
    • Streubel, A.1    Siepmann, J.2    Bodmeier, R.3
  • 167
    • 1242337285 scopus 로고    scopus 로고
    • Solubilizing excipients in oral and injectable formulations
    • Strickley RG (2004) Solubilizing excipients in oral and injectable formulations. Pharm Res 21:201-230
    • (2004) Pharm Res , vol.21 , pp. 201-230
    • Strickley, R.G.1
  • 168
    • 0030581085 scopus 로고    scopus 로고
    • Use of the intestinal and hepatic bile acid transporters for drug delivery
    • Swaan PW, Szoka FC, Oie S (1996) Use of the intestinal and hepatic bile acid transporters for drug delivery. Adv Drug Deliv Rev 20:59-82
    • (1996) Adv Drug Deliv Rev , vol.20 , pp. 59-82
    • Swaan, P.W.1    Szoka, F.C.2    Oie, S.3
  • 169
    • 0035937594 scopus 로고    scopus 로고
    • Mucoadhesive nanoparticulate systems for peptide drug delivery
    • Takeuchi H, Yamamoto H, Kawashima Y (2001) Mucoadhesive nanoparticulate systems for peptide drug delivery. Adv Drug Deliv Rev 47:39-54
    • (2001) Adv Drug Deliv Rev , vol.47 , pp. 39-54
    • Takeuchi, H.1    Yamamoto, H.2    Kawashima, Y.3
  • 170
    • 9644262439 scopus 로고    scopus 로고
    • Gastroretentive delivery systems: A mini review
    • Talukder R, Fassihi R (2004) Gastroretentive delivery systems: a mini review. Drug Dev Ind Pharm 30:1019-1028
    • (2004) Drug Dev Ind Pharm , vol.30 , pp. 1019-1028
    • Talukder, R.1    Fassihi, R.2
  • 171
    • 2642573294 scopus 로고    scopus 로고
    • Dissolution of crystallites: Surface energetic control and size effects
    • Tang R, Orme CA, Nancollas GH (2004) Dissolution of crystallites: surface energetic control and size effects. Chem Phys Chem 5:688-696
    • (2004) Chem Phys Chem , vol.5 , pp. 688-696
    • Tang, R.1    Orme, C.A.2    Nancollas, G.H.3
  • 173
    • 0029876609 scopus 로고    scopus 로고
    • Solubility, melting point and salting-out relationships in a group of secondary amine hydrochloride salts
    • Thomas E, Rubino J (1996) Solubility, melting point and salting-out relationships in a group of secondary amine hydrochloride salts. Int J Pharm 130:179-183
    • (1996) Int J Pharm , vol.130 , pp. 179-183
    • Thomas, E.1    Rubino, J.2
  • 175
    • 0032932451 scopus 로고    scopus 로고
    • Asymmetric membrane capsules for osmotic drug delivery. I. Development of a manufacturing process
    • Thombre AG, Cardinal JR, DeNoto AR, Herbig SM, Smith KL (1999) Asymmetric membrane capsules for osmotic drug delivery. I. Development of a manufacturing process. J Control Release 57:55-64
    • (1999) J Control Release , vol.57 , pp. 55-64
    • Thombre, A.G.1    Cardinal, J.R.2    Denoto, A.R.3    Herbig, S.M.4    Smith, K.L.5
  • 176
    • 2942754247 scopus 로고    scopus 로고
    • In-vitro and in-vivo evaluation of mesalazine-guar gum matrix tablets for colonic drug delivery
    • Tugcu-Demiroz F,Acartürk F, Takka S,Konus-Boyunaga O(2004) In-vitro and in-vivo evaluation of mesalazine-guar gum matrix tablets for colonic drug delivery. J Drug Target 12:105-112
    • (2004) J Drug Target , vol.12 , pp. 105-112
    • Tugcu-Demiroz, F.1    Acartürk, F.2    Takka, S.3    Konus-Boyunaga, O.4
  • 177
    • 0026574802 scopus 로고
    • Azo polymers for colon-specific drug delivery
    • Van den Mooter G, Samyn C, Kinget R (1992) Azo polymers for colon-specific drug delivery. Int J Pharm 87:37-46
    • (1992) Int J Pharm , vol.87 , pp. 37-46
    • Van Den Mooter, G.1    Samyn, C.2    Kinget, R.3
  • 178
    • 0027186271 scopus 로고
    • Azo polymers for colon-specific drug delivery. II: Influence of the type of azo polymer on the degradation by intestinal microflora
    • Van den Mooter G, Samyn C, Kinget R (1993) Azo polymers for colon-specific drug delivery. II: Influence of the type of azo polymer on the degradation by intestinal microflora. Int J Pharm 97:133-139
    • (1993) Int J Pharm , vol.97 , pp. 133-139
    • Van Den Mooter, G.1    Samyn, C.2    Kinget, R.3
  • 180
    • 0030002613 scopus 로고    scopus 로고
    • Vitro evaluation of a potential colonic delivery system that releases drug after controllable lag-time
    • Vandelli MA, Leo E, Forni F, Bernabei MT (1996) In vitro evaluation of a potential colonic delivery system that releases drug after controllable lag-time. Eur J Pharm Biopharm 43: 148-151
    • (1996) Eur J Pharm Biopharm , vol.43 , pp. 148-151
    • Vandelli, M.A.1    Leo, E.2    Forni, F.3    Bernabei, M.T.4
  • 182
    • 0037133084 scopus 로고    scopus 로고
    • Formulation aspects in the development of osmotically controlled oral drug delivery systems
    • Verma RK, Krishna DV, Garg S (2002) Formulation aspects in the development of osmotically controlled oral drug delivery systems. J Control Release 79:7-27
    • (2002) J Control Release , vol.79 , pp. 7-27
    • Verma, R.K.1    Krishna, D.V.2    Garg, S.3
  • 183
    • 0034044857 scopus 로고    scopus 로고
    • Osmotically controlled oral drug delivery
    • Verma RK, Mishra B, Garg S (2000) Osmotically controlled oral drug delivery. Drug Dev Ind Pharm 26:695-708
    • (2000) Drug Dev Ind Pharm , vol.26 , pp. 695-708
    • Verma, R.K.1    Mishra, B.2    Garg, S.3
  • 184
    • 0029887876 scopus 로고    scopus 로고
    • Vitro degradation by colonic bacteria of inulinHP incorporated in Eudragit RS films
    • Vervoort L, Kinget R (1996) In vitro degradation by colonic bacteria of inulinHP incorporated in Eudragit RS films. Int J Pharm 129:185-190
    • (1996) Int J Pharm , vol.129 , pp. 185-190
    • Vervoort, L.1    Kinget, R.2
  • 185
    • 0016163083 scopus 로고
    • Passage of particles through the wall of the gastrointestinal tract
    • Volkheimer G (1974) Passage of particles through the wall of the gastrointestinal tract. Environ Health Perspect 9:215-225
    • (1974) Environ Health Perspect , vol.9 , pp. 215-225
    • Volkheimer, G.1
  • 186
    • 0030581089 scopus 로고    scopus 로고
    • The intestinal peptide carrier: A potential transport system for small peptide derived drugs
    • Walter E, Kissel T, Amidon GL (1996) The intestinal peptide carrier: a potential transport system for small peptide derived drugs. Adv Drug Deliv Rev 20:33-58
    • (1996) Adv Drug Deliv Rev , vol.20 , pp. 33-58
    • Walter, E.1    Kissel, T.2    Amidon, G.L.3
  • 187
    • 0024351034 scopus 로고
    • The influence of different formula diets and different pharmaceutical formulations on the systemic bioavailabilty of paracetamol, gall bladder size and plasma glucose
    • Walter SIE, De Vries JX, Nickel B, Stenzhorn G, Weber E (1989) The influence of different formula diets and different pharmaceutical formulations on the systemic bioavailabilty of paracetamol, gall bladder size and plasma glucose. Int J Clin Pharmacol Exp Ther Toxicol 27:544-550
    • (1989) Int J Clin Pharmacol Exp Ther Toxicol , vol.27 , pp. 544-550
    • Walter, S.I.E.1    De Vries, J.X.2    Nickel, B.3    Stenzhorn, G.4    Weber, E.5
  • 189
    • 34249677860 scopus 로고    scopus 로고
    • A critical review of gastric retentive controlled drug delivery
    • Waterman KC (2007) A critical review of gastric retentive controlled drug delivery. Pharm Dev Technol 12:1-10
    • (2007) Pharm Dev Technol , vol.12 , pp. 1-10
    • Waterman, K.C.1
  • 190
    • 6344256207 scopus 로고    scopus 로고
    • Binding and uptake of wheat germ agglutinin-decorated PLGA-nanospheres by Caco-2 monolayers
    • Weissenboeck A, Bogner E, Wirth M, Gabor F (2004) Binding and uptake of wheat germ agglutinin-decorated PLGA-nanospheres by Caco-2 monolayers. Pharm Res 21:1919-1925
    • (2004) Pharm Res , vol.21 , pp. 1919-1925
    • Weissenboeck, A.1    Bogner, E.2    Wirth, M.3    Gabor, F.4
  • 191
    • 20444395842 scopus 로고    scopus 로고
    • Magnetic marker monitoring: An application of biomagnetic measurement instrumentation and principles for the determination of the gastrointestinal behaviour of magnetically marked solid dosage forms
    • Weitschies W, Kosch O, Moennikes H, Trahms L (2005) Magnetic marker monitoring: an application of biomagnetic measurement instrumentation and principles for the determination of the gastrointestinal behaviour of magnetically marked solid dosage forms. Adv Drug Deliv Rev 57:1210-1222
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 1210-1222
    • Weitschies, W.1    Kosch, O.2    Moennikes, H.3    Trahms, L.4
  • 192
    • 46749122375 scopus 로고    scopus 로고
    • Safe and effective permeation enhancers for oral drug delivery
    • Whitehead K, Karr N, Mitragotri S (2008) Safe and effective permeation enhancers for oral drug delivery. Pharm Res 25:1782-1788
    • (2008) Pharm Res , vol.25 , pp. 1782-1788
    • Whitehead, K.1    Karr, N.2    Mitragotri, S.3
  • 193
    • 0036709119 scopus 로고    scopus 로고
    • Lectin-mediated drug delivery: Discrimination between cytoadhesion and cytoinvasion and evidence for lysosomal accumulation of wheat germ agglutinin in the Caco-2 model
    • Wirth M, Kneuer C, Lehr CM, Gabor F (2002) Lectin-mediated drug delivery: discrimination between cytoadhesion and cytoinvasion and evidence for lysosomal accumulation of wheat germ agglutinin in the Caco-2 model. J Drug Target 10:439-448
    • (2002) J Drug Target , vol.10 , pp. 439-448
    • Wirth, M.1    Kneuer, C.2    Lehr, C.M.3    Gabor, F.4
  • 194
    • 0037436032 scopus 로고    scopus 로고
    • Dendrimer conjugates for colonic delivery of 5-aminosalicylic acid
    • Wiwattanapatapee R, Lomlim L, Saramunee K (2003) Dendrimer conjugates for colonic delivery of 5-aminosalicylic acid. J Control Release 88:1-9
    • (2003) J Control Release , vol.88 , pp. 1-9
    • Wiwattanapatapee, R.1    Lomlim, L.2    Saramunee, K.3
  • 195
    • 0032399926 scopus 로고    scopus 로고
    • A new understanding of the relationship between solubility and particle size
    • Wu W, Nancollas GH (1998) A new understanding of the relationship between solubility and particle size. J Solution Chem 27:521-531
    • (1998) J Solution Chem , vol.27 , pp. 521-531
    • Wu, W.1    Nancollas, G.H.2
  • 196
    • 20844446627 scopus 로고    scopus 로고
    • The role of biopharmaceutics in the development of a clinical nanoparticle formulation of MK-0869: A Beagle dog model predicts improved bioavailability and diminished food effect on absorption in human
    • Wu Y, Loper A, Landis E, Hettrick L, Novak L, Lynn K, Chen C, Thompson K, Higgins R, Batra U, Shelukar S, Kwei G, Storey D (2004) The role of biopharmaceutics in the development of a clinical nanoparticle formulation of MK-0869: a Beagle dog model predicts improved bioavailability and diminished food effect on absorption in human. Int J Pharm 285:135-146
    • (2004) Int J Pharm , vol.285 , pp. 135-146
    • Wu, Y.1    Loper, A.2    Landis, E.3    Hettrick, L.4    Novak, L.5    Lynn, K.6    Chen, C.7    Thompson, K.8    Higgins, R.9    Batra, U.10    Shelukar, S.11    Kwei, G.12    Storey, D.13
  • 197
    • 0033046507 scopus 로고    scopus 로고
    • A new intragastric delivery system for the treatment of Helicobacter pylori associated gastric ulcer: In vitro evaluation
    • Yang L, Eshraghi J, Fassihi R (1999) A new intragastric delivery system for the treatment of Helicobacter pylori associated gastric ulcer: in vitro evaluation. J Control Release 57:215-222
    • (1999) J Control Release , vol.57 , pp. 215-222
    • Yang, L.1    Eshraghi, J.2    Fassihi, R.3
  • 199
    • 0028597539 scopus 로고
    • Crystallization of indomethacin from the amorphous state below and above its glass transition temperature
    • Yoshioka M, Hancock BC, Zografi G (1994) Crystallization of indomethacin from the amorphous state below and above its glass transition temperature. J Pharm Sci 83:1700-1705
    • (1994) J Pharm Sci , vol.83 , pp. 1700-1705
    • Yoshioka, M.1    Hancock, B.C.2    Zografi, G.3
  • 200
    • 0029056118 scopus 로고
    • Inhibition of indomethacin crystallization in poly (vinylpyrrolidone) coprecipitates
    • Yoshioka M, Hancock BC, Zografi G (1995) Inhibition of indomethacin crystallization in poly (vinylpyrrolidone) coprecipitates. J Pharm Sci 84:983-986
    • (1995) J Pharm Sci , vol.84 , pp. 983-986
    • Yoshioka, M.1    Hancock, B.C.2    Zografi, G.3
  • 202
    • 0037018961 scopus 로고    scopus 로고
    • An in vitro evaluation of a chitosan-containing multiparticulate system for macromolecule delivery to the colon
    • Zhang H, Alsarra IA, Neau SH (2002) An in vitro evaluation of a chitosan-containing multiparticulate system for macromolecule delivery to the colon. Int J Pharm 239:197-205
    • (2002) Int J Pharm , vol.239 , pp. 197-205
    • Zhang, H.1    Alsarra, I.A.2    Neau, S.H.3


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