Temporal requirements of insulin/IGF-1 signaling for proteotoxicity protection

Aging Cell

Volumn 9, Issue 2, 2010, Pages 126-134

  Cohen, Ehud ^a,b   Du, Deguo ^c   Joyce, Derek ^a   Kapernick, Erik A ^a   Volovik, Yuli ^b   Kelly, Jeffery W ^c   Dillin, Andrew ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Caenorhabditis elegans; Insulin IGF 1 signaling; Longevity; Proteotoxicity

Indexed keywords

AMYLOID BETA PROTEIN; HEAT SHOCK TRANSCRIPTION FACTOR 1; INSULIN; SOMATOMEDIN A; TRANSCRIPTION FACTOR DAF 16; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); CAENORHABDITIS ELEGANS PROTEIN; DAF 16 PROTEIN, C ELEGANS; DAF 2 PROTEIN, C ELEGANS; DAF-16 PROTEIN, C ELEGANS; DAF-2 PROTEIN, C ELEGANS; HEAT SHOCK FACTOR 1, C ELEGANS; HEAT SHOCK FACTOR-1, C ELEGANS; INSULIN RECEPTOR; PEPTIDE FRAGMENT; SOMATOMEDIN C; TRANSCRIPTION FACTOR;

ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DEGENERATIVE DISEASE; GENE EXPRESSION REGULATION; LIFESPAN; LONGEVITY; NEMATODE; NEUROLOGIC DISEASE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEOTOXICITY; REPRODUCTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSGENICS; ACTIVE TRANSPORT; ANIMAL; CELL AGING; GENETICS; GROWTH, DEVELOPMENT AND AGING; LARVA; METABOLISM;

ANIMALIA; CAENORHABDITIS ELEGANS; NEMATODA;

ACTIVE TRANSPORT, CELL NUCLEUS; AMYLOID BETA-PROTEIN; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL AGING; INSULIN; INSULIN-LIKE GROWTH FACTOR I; LARVA; PEPTIDE FRAGMENTS; RECEPTOR, INSULIN; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 77953247518     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2009.00541.x     Document Type: Article

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