-
1
-
-
35348850734
-
Hematopoietic cytokine receptor signaling
-
Baker S.J., Rane S.G., and Reddy E.P. Hematopoietic cytokine receptor signaling. Oncogene 26 (2007) 6724-6737
-
(2007)
Oncogene
, vol.26
, pp. 6724-6737
-
-
Baker, S.J.1
Rane, S.G.2
Reddy, E.P.3
-
2
-
-
35348875375
-
Cytokine receptors and hematopoietic differentiation
-
Robb L. Cytokine receptors and hematopoietic differentiation. Oncogene 26 (2007) 6715-6723
-
(2007)
Oncogene
, vol.26
, pp. 6715-6723
-
-
Robb, L.1
-
3
-
-
35348834097
-
Aberrant cytokine signaling in leukemia
-
Van Etten RA. Aberrant cytokine signaling in leukemia. Oncogene 26 (2007) 6738-6749
-
(2007)
Oncogene
, vol.26
, pp. 6738-6749
-
-
Van Etten RA1
-
4
-
-
14644425319
-
Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia
-
Ren R. Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia. Nat Rev Cancer 5 (2005) 172-183
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 172-183
-
-
Ren, R.1
-
5
-
-
33947328520
-
Oncogenes in myeloproliferative disorders
-
Tefferi A., and Gilliland D.G. Oncogenes in myeloproliferative disorders. Cell Cycle 6 (2007) 550-566
-
(2007)
Cell Cycle
, vol.6
, pp. 550-566
-
-
Tefferi, A.1
Gilliland, D.G.2
-
6
-
-
33845436745
-
The myeloproliferative disorders
-
Campbell P.J., and Green A.R. The myeloproliferative disorders. N Engl J Med 355 (2006) 2452-2466
-
(2006)
N Engl J Med
, vol.355
, pp. 2452-2466
-
-
Campbell, P.J.1
Green, A.R.2
-
7
-
-
0036720398
-
The roles of FLT3 in hematopoiesis and leukemia
-
Gilliland D.G., and Griffin J.D. The roles of FLT3 in hematopoiesis and leukemia. Blood 100 (2002) 1532-1542
-
(2002)
Blood
, vol.100
, pp. 1532-1542
-
-
Gilliland, D.G.1
Griffin, J.D.2
-
8
-
-
51649115383
-
Mast cells and mastocytosis
-
Metcalfe D.D. Mast cells and mastocytosis. Blood 112 (2008) 946-956
-
(2008)
Blood
, vol.112
, pp. 946-956
-
-
Metcalfe, D.D.1
-
9
-
-
0035811366
-
Lnk adaptor: novel negative regulator of B cell lymphopoiesis
-
2001(85):PE1
-
Rudd C.E. Lnk adaptor: novel negative regulator of B cell lymphopoiesis. Sci STKE (2001) 2001(85):PE1
-
(2001)
Sci STKE
-
-
Rudd, C.E.1
-
10
-
-
33845663497
-
Carter-Su C. SH2B1 (SH2-B) and JAK2: a multifunctional adaptor protein and kinase made for each other
-
Maures T.J., and Kurzer J.H. Carter-Su C. SH2B1 (SH2-B) and JAK2: a multifunctional adaptor protein and kinase made for each other. Trends Endocrinol Metab 18 (2007) 38-45
-
(2007)
Trends Endocrinol Metab
, vol.18
, pp. 38-45
-
-
Maures, T.J.1
Kurzer, J.H.2
-
11
-
-
0034872381
-
Functional effects of APS and SH2-B on insulin receptor signaling
-
Ahmed Z., and Pillay T.S. Functional effects of APS and SH2-B on insulin receptor signaling. Biochem Soc Trans Pt 4 (2001) 529-534
-
(2001)
Biochem Soc Trans
, Issue.PART 4
, pp. 529-534
-
-
Ahmed, Z.1
Pillay, T.S.2
-
12
-
-
0037148516
-
Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein
-
Takaki S., Morita H., Tezuka Y., and Takatsu K. Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein. Lnk. J Exp Med 195 (2002) 151-160
-
(2002)
Lnk. J Exp Med
, vol.195
, pp. 151-160
-
-
Takaki, S.1
Morita, H.2
Tezuka, Y.3
Takatsu, K.4
-
13
-
-
0037124306
-
Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice
-
Velazquez L., Cheng A.M., Fleming H.E., et al. Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice. J Exp Med 195 (2002) 1599-1611
-
(2002)
J Exp Med
, vol.195
, pp. 1599-1611
-
-
Velazquez, L.1
Cheng, A.M.2
Fleming, H.E.3
-
14
-
-
33746591727
-
Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK
-
Buza-Vidas N., Antonchuk J., Qian H., et al. Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK. Genes Dev 20 (2006) 2018-2023
-
(2006)
Genes Dev
, vol.20
, pp. 2018-2023
-
-
Buza-Vidas, N.1
Antonchuk, J.2
Qian, H.3
-
15
-
-
33847772982
-
Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction
-
Seita J., Ema H., Ooehara J., et al. Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction. Proc Natl Acad Sci U S A 104 (2007) 2349-2354
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 2349-2354
-
-
Seita, J.1
Ema, H.2
Ooehara, J.3
-
16
-
-
4544277651
-
Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis
-
Tong W., and Lodish H.F. Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis. J Exp Med 200 (2004) 569-580
-
(2004)
J Exp Med
, vol.200
, pp. 569-580
-
-
Tong, W.1
Lodish, H.F.2
-
17
-
-
20444426803
-
Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways
-
Tong W., Zhang J., and Lodish H.F. Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways. Blood 105 (2005) 4604-4612
-
(2005)
Blood
, vol.105
, pp. 4604-4612
-
-
Tong, W.1
Zhang, J.2
Lodish, H.F.3
-
18
-
-
48749084130
-
Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2
-
Bersenev A., Wu C., Balcerek J., and Tong W. Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2. J Clin Invest 18 (2008) 2832-2844
-
(2008)
J Clin Invest
, vol.18
, pp. 2832-2844
-
-
Bersenev, A.1
Wu, C.2
Balcerek, J.3
Tong, W.4
-
19
-
-
33745982917
-
The adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathways
-
Fitau J., Boulday G., Coulon F., Quillard T., and Charreau B. The adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathways. J Biol Chem. 281 (2006) 20148-20159
-
(2006)
J Biol Chem.
, vol.281
, pp. 20148-20159
-
-
Fitau, J.1
Boulday, G.2
Coulon, F.3
Quillard, T.4
Charreau, B.5
-
20
-
-
36148995898
-
Adaptor protein Lnk negatively regulates the mutant MPL, MPLW515L associated with myeloproliferative disorders
-
Gery S., Gueller S., Chumakova K., et al. Adaptor protein Lnk negatively regulates the mutant MPL, MPLW515L associated with myeloproliferative disorders. Blood 110 (2007) 3360-3364
-
(2007)
Blood
, vol.110
, pp. 3360-3364
-
-
Gery, S.1
Gueller, S.2
Chumakova, K.3
-
21
-
-
33846660947
-
JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis
-
Scott L.M., Tong W., Levine R.L., et al. JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis. N Engl J Med 356 (2007) 459-468
-
(2007)
N Engl J Med
, vol.356
, pp. 459-468
-
-
Scott, L.M.1
Tong, W.2
Levine, R.L.3
-
22
-
-
34447642422
-
Molecular pathogenesis and therapy of polycythemia induced in mice by JAK2 V617F
-
Zaleskas V.M., Krause D.S., Lazarides K., et al. Molecular pathogenesis and therapy of polycythemia induced in mice by JAK2 V617F. PLoS ONE 1 (2006) e18
-
(2006)
PLoS ONE
, vol.1
-
-
Zaleskas, V.M.1
Krause, D.S.2
Lazarides, K.3
-
24
-
-
0024563574
-
Expression cloning of the murine erythropoietin receptor
-
D'Andrea A.D., Lodish H.F., and Wong G.G. Expression cloning of the murine erythropoietin receptor. Cell 57 (1989) 277-285
-
(1989)
Cell
, vol.57
, pp. 277-285
-
-
D'Andrea, A.D.1
Lodish, H.F.2
Wong, G.G.3
-
25
-
-
38049160143
-
Sustained suppression of Bcr-Abl-driven lymphoid leukemia by microRNA mimics
-
McLaughlin J., Cheng D., Singer O., et al. Sustained suppression of Bcr-Abl-driven lymphoid leukemia by microRNA mimics. Proc Natl Acad Sci U S A 104 (2007) 20501-20506
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 20501-20506
-
-
McLaughlin, J.1
Cheng, D.2
Singer, O.3
-
26
-
-
30044437118
-
Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation
-
Lu X., Levine R., Tong W., et al. Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation. Proc Natl Acad Sci U S A 102 (2005) 18962-18967
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 18962-18967
-
-
Lu, X.1
Levine, R.2
Tong, W.3
-
27
-
-
64249127642
-
Adaptor protein Lnk binds to PDGFRA, PDGFRB and FIP1L1-PDGFRA, but not to the TEL-PDGFRB fusion protein
-
Gueller S., Gery S., and Koeffler H.P. Adaptor protein Lnk binds to PDGFRA, PDGFRB and FIP1L1-PDGFRA, but not to the TEL-PDGFRB fusion protein. Blood (ASH Annual Meeting Abstracts) 110 (2007) 2213
-
(2007)
Blood (ASH Annual Meeting Abstracts)
, vol.110
, pp. 2213
-
-
Gueller, S.1
Gery, S.2
Koeffler, H.P.3
-
28
-
-
0242552572
-
Regulation of hematopoietic development in the aorta-gonad-mesonephros region mediated by Lnk adaptor protein
-
Nobuhisa I., Tazizawa M., Takaki S., et al. Regulation of hematopoietic development in the aorta-gonad-mesonephros region mediated by Lnk adaptor protein. Mol Cell Biol 23 (2003) 8486-8494
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8486-8494
-
-
Nobuhisa, I.1
Tazizawa, M.2
Takaki, S.3
-
29
-
-
0037438342
-
Impaired lymphopoiesis and altered B cell subpopulations in mice overexpressing Lnk adaptor protein
-
Takaki S., Tezuka Y., Sauer K., et al. Impaired lymphopoiesis and altered B cell subpopulations in mice overexpressing Lnk adaptor protein. J Immunol 170 (2003) 703-710
-
(2003)
J Immunol
, vol.170
, pp. 703-710
-
-
Takaki, S.1
Tezuka, Y.2
Sauer, K.3
-
30
-
-
0029587597
-
Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinase
-
Huang X., Li Y., Tanaka K., Moore K.G., and Hayashi J.I. Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinase. Proc Natl Acad Sci U S A 92 (1995) 11618-11622
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 11618-11622
-
-
Huang, X.1
Li, Y.2
Tanaka, K.3
Moore, K.G.4
Hayashi, J.I.5
-
31
-
-
0034661522
-
The Grb2 binding site is required for the induction of chronic myeloid leukemia-like disease in mice by the Bcr/Abl tyrosine kinase
-
Million R.P., and Van Etten R.A. The Grb2 binding site is required for the induction of chronic myeloid leukemia-like disease in mice by the Bcr/Abl tyrosine kinase. Blood 96 (2000) 664-670
-
(2000)
Blood
, vol.96
, pp. 664-670
-
-
Million, R.P.1
Van Etten, R.A.2
-
32
-
-
24344452505
-
Phosphatidylinositol 3-kinase p85{alpha} subunit-dependent interaction with BCR/ABL-related fusion tyrosine kinases: molecular mechanisms and biological consequences
-
Ren S.Y., Bolton E., Mohi M.G., Morrione A., Neel B.G., and Skorski T. Phosphatidylinositol 3-kinase p85{alpha} subunit-dependent interaction with BCR/ABL-related fusion tyrosine kinases: molecular mechanisms and biological consequences. Mol Cell Biol 25 (2005) 8001-8008
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8001-8008
-
-
Ren, S.Y.1
Bolton, E.2
Mohi, M.G.3
Morrione, A.4
Neel, B.G.5
Skorski, T.6
-
33
-
-
31544459272
-
Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies
-
Schittenhelm M.M., Shiraga S., Schroeder A., et al. Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies. Cancer Res 66 (2006) 473-481
-
(2006)
Cancer Res
, vol.66
, pp. 473-481
-
-
Schittenhelm, M.M.1
Shiraga, S.2
Schroeder, A.3
-
34
-
-
23344440655
-
Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases
-
Carter T.A., Wodicka L.M., Shah N.P., et al. Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases. Proc Natl Acad Sci U S A 102 (2005) 11011-11016
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 11011-11016
-
-
Carter, T.A.1
Wodicka, L.M.2
Shah, N.P.3
-
35
-
-
0036325621
-
The protein tyrosine kinase inhibitor SU5614 inhibits VEGF-induced endothelial cell sprouting and induces growth arrest and apoptosis by inhibition of c-kit in AML cells
-
Spiekermann K., Faber F., Voswinckel R., and Hiddemann W. The protein tyrosine kinase inhibitor SU5614 inhibits VEGF-induced endothelial cell sprouting and induces growth arrest and apoptosis by inhibition of c-kit in AML cells. Exp Hematol 30 (2002) 767-773
-
(2002)
Exp Hematol
, vol.30
, pp. 767-773
-
-
Spiekermann, K.1
Faber, F.2
Voswinckel, R.3
Hiddemann, W.4
-
36
-
-
19444371232
-
STI 571 inhibition effect on KITAsn822Lys-mediated signal transduction cascade
-
Beghini A., Bellini M., Magnani I., et al. STI 571 inhibition effect on KITAsn822Lys-mediated signal transduction cascade. Exp Hematol 33 (2005) 682-688
-
(2005)
Exp Hematol
, vol.33
, pp. 682-688
-
-
Beghini, A.1
Bellini, M.2
Magnani, I.3
|