Physiologically based pharmacokinetic model for developmental exposures to TCDD in the rat

Toxicological Sciences

Volumn 80, Issue 1, 2004, Pages 115-133

  Emond, Claude ^a,b   Birnbaum, Linda S ^b   DeVito, Michael J ^a,b  

^a NATIONAL RESEARCH COUNCIL   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Developmental; Dioxin; PBPK; Rat; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; FEMALE GENITAL SYSTEM; FETUS; FETUS DEVELOPMENT; FETUS GROWTH; GESTATION PERIOD; NONHUMAN; PLACENTA DEVELOPMENT; PREGNANCY; QUANTITATIVE ANALYSIS; RAT; SENSITIVITY ANALYSIS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TISSUE DISTRIBUTION;

ANIMALS; ENVIRONMENTAL POLLUTANTS; FEMALE; FETUS; MALE; MATERNAL EXPOSURE; MATERNAL-FETAL EXCHANGE; MODELS, BIOLOGICAL; PLACENTA; PREGNANCY; RATS; RATS, LONG-EVANS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TETRACHLORODIBENZODIOXIN; TIME FACTORS; TISSUE DISTRIBUTION; TOXICITY TESTS;

RODENTIA;

EID: 3242800512     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfh117     Document Type: Article

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