Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the developing male Wistar(Han) rat. II: Chronic dosing causes developmental delay

Toxicological Sciences

Volumn 99, Issue 1, 2007, Pages 224-233

  Bell, David R ^a   Clode, Sally ^b   Fan, Ming Qi ^a   Fernandes, Alwyn ^e   Foster, Paul M D ^c   Jiang, Tao ^a   Loizou, George ^d   MacNicoll, Alan ^e   Miller, Brian G ^f   Rose, Martin ^e   Tran, Lang ^f   White, Shaun ^e  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UK   (United Kingdom)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^d HEALTH AND SAFETY LABORATORY   (United Kingdom)

^e CENTRAL SCIENCE LABORATORY   (United Kingdom)

^f INSTITUTE OF OCCUPATIONAL MEDICINE   (United Kingdom)

Author keywords

Developmental toxicity; Dioxin; Sperm

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DELAYED PUBERTY; DEVELOPMENTAL DISORDER; DIETARY INTAKE; DOSE RESPONSE; FEMALE; HISTOPATHOLOGY; LEARNING TEST; MALE; MALE GENITAL SYSTEM DISEASE; MATERNAL TREATMENT; NEWBORN DEATH; NONHUMAN; ORGAN WEIGHT; PRENATAL EXPOSURE; PREPUCE; RAT; REPRODUCTIVE TOXICITY; SPERMATOZOON COUNT; TOXICITY TESTING;

ADMINISTRATION, ORAL; ANIMALS; BEHAVIOR, ANIMAL; BODY WEIGHT; DIET; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FEMALE; FERTILITY; GENITALIA, MALE; MALE; MATERNAL EXPOSURE; MOTOR ACTIVITY; PERINEUM; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR; SEXUAL MATURATION; SPERMATOZOA; TETRACHLORODIBENZODIOXIN; TOXICITY TESTS, CHRONIC;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 34547911449     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm141     Document Type: Article

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