Disruption of thyroid hormone homeostasis at weaning of Holtzman rats by lactational but not in utero exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin

Toxicological Sciences

Volumn 85, Issue 1, 2005, Pages 607-614

  Nishimura, Noriko ^a   Yonemoto, Junzo ^a   Nishimura, Hisao ^b   Ikushiro, Shin Ichi ^c   Tohyama, Chiharu ^a  

^a NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

^b Japan   (Japan)

^c UNIVERSITY OF HYOGO   (Japan)

Author keywords

Hypothyroxinemia; Lactational exposure; TCDD; Thyroxin

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CYTOCHROME P450 1A1; GLUCURONOSYLTRANSFERASE; GLYCOSYLTRANSFERASE; MESSENGER RNA; POLYPEPTIDE; THYROID HORMONE; THYROTROPIN; THYROXINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST MILK; CONTROLLED STUDY; ENDOCRINE DISEASE; ENVIRONMENTAL EXPOSURE; FEMALE; FREE THYROXINE INDEX; GESTATIONAL AGE; HOMEOSTASIS; HORMONE METABOLISM; HYPOTHYROXINEMIA; IMMUNOHISTOCHEMISTRY; LACTATION; LIVER; MALE; MILK LEVEL; NEWBORN PERIOD; NONHUMAN; PRENATAL EXPOSURE; RAT; RAT STRAIN; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; TISSUE DISTRIBUTION; WEANING;

ANIMALS; ANIMALS, SUCKLING; CYTOCHROME P-450 CYP1A1; ENVIRONMENTAL POLLUTANTS; FEMALE; GESTATIONAL AGE; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; LIVER; MALE; MILK; MONOSACCHARIDE TRANSPORT PROTEINS; ORGAN SIZE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TETRACHLORODIBENZODIOXIN; THYROID GLAND; THYROID HORMONES; WEANING;

EID: 18144370812     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfi122     Document Type: Article

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