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Volumn 184, Issue 8, 2010, Pages 4497-4509

Inhibitor of NF-κB kinases α and β are both essential for high mobility group box 1-mediated chemotaxis

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; HIGH MOBILITY GROUP B1 PROTEIN; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; I KAPPA B KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P52; TRANSCRIPTION FACTOR RELB; CHUK PROTEIN, MOUSE; I KAPPA B KINASE; IKBKB PROTEIN, MOUSE; RECOMBINANT PROTEIN;

EID: 77952783551     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0903131     Document Type: Article
Times cited : (84)

References (81)
  • 1
    • 0037062934 scopus 로고    scopus 로고
    • Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    • Scaffidi, P., T. Misteli, and M. E. Bianchi. 2002. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418: 191-195.
    • (2002) Nature , vol.418 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 3
    • 17144376810 scopus 로고    scopus 로고
    • High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
    • Lotze, M. T., and K. J. Tracey. 2005. High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat. Rev. Immunol. 5: 331-342.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 331-342
    • Lotze, M.T.1    Tracey, K.J.2
  • 4
    • 70149084792 scopus 로고    scopus 로고
    • HMGB1 loves company
    • Bianchi, M. E. 2009. HMGB1 loves company. J. Leukoc. Biol. 86: 573-576.
    • (2009) J. Leukoc. Biol. , vol.86 , pp. 573-576
    • Bianchi, M.E.1
  • 5
    • 0028851635 scopus 로고
    • The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of RAGE and amphoterin in the developing nervous system
    • Hori, O., J. Brett, T. Slattery, R. Cao, J. Zhang, J. X. Chen, M. Nagashima, E. R. Lundh, S. Vijay, D. Nitecki, et al. 1995. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of RAGE and amphoterin in the developing nervous system. J. Biol. Chem. 270: 25752-25761.
    • (1995) J. Biol. Chem. , vol.270 , pp. 25752-25761
    • Hori, O.1    Brett, J.2    Slattery, T.3    Cao, R.4    Zhang, J.5    Chen, J.X.6    Nagashima, M.7    Lundh, E.R.8    Vijay, S.9    Nitecki, D.10
  • 11
    • 34547728254 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE) in a dash to the rescue: Inflammatory signals gone awry in the primal response to stress
    • Herold, K., B. Moser, Y. Chen, S. Zeng, S. F. Yan, R. Ramasamy, J. Emond, R. Clynes, and A. M. Schmidt. 2007. Receptor for advanced glycation end products (RAGE) in a dash to the rescue: inflammatory signals gone awry in the primal response to stress. J. Leukoc. Biol. 82: 204-212.
    • (2007) J. Leukoc. Biol. , vol.82 , pp. 204-212
    • Herold, K.1    Moser, B.2    Chen, Y.3    Zeng, S.4    Yan, S.F.5    Ramasamy, R.6    Emond, J.7    Clynes, R.8    Schmidt, A.M.9
  • 13
    • 57749122052 scopus 로고    scopus 로고
    • Interaction of the RAGE cytoplasmic domain with diaphanous-1 is required for ligand-stimulated cellular migration through activation of Rac1 and Cdc42
    • Hudson, B. I., A. Z. Kalea, M. Del Mar Arriero, E. Harja, E. Boulanger, V. D'Agati, and A. M. Schmidt. 2008. Interaction of the RAGE cytoplasmic domain with diaphanous-1 is required for ligand-stimulated cellular migration through activation of Rac1 and Cdc42. J. Biol. Chem. 283: 34457-34468.
    • (2008) J. Biol. Chem. , vol.283 , pp. 34457-34468
    • Hudson, B.I.1    Kalea, A.Z.2    Del Mar Arriero, M.3    Harja, E.4    Boulanger, E.5    D'Agati, V.6    Schmidt, A.M.7
  • 14
    • 35349009132 scopus 로고    scopus 로고
    • Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-kappaB activation
    • Palumbo, R., B. G. Galvez, T. Pusterla, F. De Marchis, G. Cossu, K. B. Marcu, and M. E. Bianchi. 2007. Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-kappaB activation. J. Cell Biol. 179: 33-40.
    • (2007) J. Cell Biol. , vol.179 , pp. 33-40
    • Palumbo, R.1    Galvez, B.G.2    Pusterla, T.3    De Marchis, F.4    Cossu, G.5    Marcu, K.B.6    Bianchi, M.E.7
  • 16
    • 34547616284 scopus 로고    scopus 로고
    • Dual role of mitochondrial reactive oxygen species in hypoxia signaling: Activation of nuclear factor-kappaB via c-SRC and oxidant-dependent cell death
    • Lluis, J. M., F. Buricchi, P. Chiarugi, A. Morales, and J. C. Fernandez-Checa. 2007. Dual role of mitochondrial reactive oxygen species in hypoxia signaling: activation of nuclear factor-kappaB via c-SRC and oxidant-dependent cell death. Cancer Res. 67: 7368-7377.
    • (2007) Cancer Res. , vol.67 , pp. 7368-7377
    • Lluis, J.M.1    Buricchi, F.2    Chiarugi, P.3    Morales, A.4    Fernandez-Checa, J.C.5
  • 17
    • 38449099025 scopus 로고    scopus 로고
    • Src tyrosine kinases mediate activations of NF-kappaB and integrin signal during lipopolysaccharide-induced acute lung injury
    • Lee, H. S., C. Moon, H. W. Lee, E. M. Park, M. S. Cho, and J. L. Kang. 2007. Src tyrosine kinases mediate activations of NF-kappaB and integrin signal during lipopolysaccharide-induced acute lung injury. J. Immunol. 179: 7001-7011.
    • (2007) J. Immunol. , vol.179 , pp. 7001-7011
    • Lee, H.S.1    Moon, C.2    Lee, H.W.3    Park, E.M.4    Cho, M.S.5    Kang, J.L.6
  • 18
    • 33845768987 scopus 로고    scopus 로고
    • Integrating cell-signalling pathways with NF-kappaB and IKK function
    • Perkins, N. D. 2007. Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat. Rev. Mol. Cell Biol. 8: 49-62.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 49-62
    • Perkins, N.D.1
  • 19
    • 38949094588 scopus 로고    scopus 로고
    • Thrombin-induced IL-6 production in human synovial fibroblasts is mediated by PAR1, phospholipase C, protein kinase C alpha, c-Src, NF-kappa B and p300 pathway
    • Chiu, Y. C., Y. C. Fong, C. H. Lai, C. H. Hung, H. C. Hsu, T. S. Lee, R. S. Yang, W. M. Fu, and C. H. Tang. 2008. Thrombin-induced IL-6 production in human synovial fibroblasts is mediated by PAR1, phospholipase C, protein kinase C alpha, c-Src, NF-kappa B and p300 pathway. Mol. Immunol. 45: 1587-1599.
    • (2008) Mol. Immunol. , vol.45 , pp. 1587-1599
    • Chiu, Y.C.1    Fong, Y.C.2    Lai, C.H.3    Hung, C.H.4    Hsu, H.C.5    Lee, T.S.6    Yang, R.S.7    Fu, W.M.8    Tang, C.H.9
  • 20
    • 25844459154 scopus 로고    scopus 로고
    • NF-kappaB: Linking inflammation and immunity to cancer development and progression
    • Karin, M., and F. R. Greten. 2005. NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat. Rev. Immunol. 5: 749-759.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 21
    • 2342464085 scopus 로고    scopus 로고
    • The two NF-kappaB activation pathways and their role in innate and adaptive immunity
    • Bonizzi, G., and M. Karin. 2004. The two NF-kappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol. 25: 280-288.
    • (2004) Trends Immunol. , vol.25 , pp. 280-288
    • Bonizzi, G.1    Karin, M.2
  • 23
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signaling
    • Hayden, M. S., and S. Ghosh. 2008. Shared principles in NF-kappaB signaling. Cell 132: 344-362.
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 24
    • 0442307969 scopus 로고    scopus 로고
    • IkappaB kinases: Key regulators of the NF-kappaB pathway
    • Yamamoto, Y., and R. B. Gaynor. 2004. IkappaB kinases: key regulators of the NF-kappaB pathway. Trends Biochem. Sci. 29: 72-79.
    • (2004) Trends Biochem. Sci. , vol.29 , pp. 72-79
    • Yamamoto, Y.1    Gaynor, R.B.2
  • 25
    • 33750443289 scopus 로고    scopus 로고
    • IkappaB kinase complexes: Gateways to NF-kappaB activation and transcription
    • Scheidereit, C. 2006. IkappaB kinase complexes: gateways to NF-kappaB activation and transcription. Oncogene 25: 6685-6705.
    • (2006) Oncogene , vol.25 , pp. 6685-6705
    • Scheidereit, C.1
  • 26
    • 33846481019 scopus 로고    scopus 로고
    • IkappaB kinase subunits alpha and gamma are required for activation of NF-kappaB and induction of apoptosis by mammalian reovirus
    • Hansberger, M. W., J. A. Campbell, P. Danthi, P. Arrate, K. N. Pennington, K. B. Marcu, D. W. Ballard, and T. S. Dermody. 2007. IkappaB kinase subunits alpha and gamma are required for activation of NF-kappaB and induction of apoptosis by mammalian reovirus. J. Virol. 81: 1360-1371.
    • (2007) J. Virol. , vol.81 , pp. 1360-1371
    • Hansberger, M.W.1    Campbell, J.A.2    Danthi, P.3    Arrate, P.4    Pennington, K.N.5    Marcu, K.B.6    Ballard, D.W.7    Dermody, T.S.8
  • 27
    • 17844386319 scopus 로고    scopus 로고
    • IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation
    • Lawrence, T., M. Bebien, G. Y. Liu, V. Nizet, and M. Karin. 2005. IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. Nature 434: 1138-1143.
    • (2005) Nature , vol.434 , pp. 1138-1143
    • Lawrence, T.1    Bebien, M.2    Liu, G.Y.3    Nizet, V.4    Karin, M.5
  • 28
    • 24644433852 scopus 로고    scopus 로고
    • Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1)
    • Li, Q., Q. Lu, V. Bottero, G. Estepa, L. Morrison, F. Mercurio, and I. M. Verma. 2005. Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1). Proc. Natl. Acad. Sci. USA 102: 12425-12430.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 12425-12430
    • Li, Q.1    Lu, Q.2    Bottero, V.3    Estepa, G.4    Morrison, L.5    Mercurio, F.6    Verma, I.M.7
  • 29
    • 34249039031 scopus 로고    scopus 로고
    • Proinflammatory stimuli induce IKKalpha-mediated phosphorylation of PIAS1 to restrict inflammation and immunity
    • Liu, B., Y. Yang, V. Chernishof, R. R. Loo, H. Jang, S. Tahk, R. Yang, S. Mink, D. Shultz, C. J. Bellone, et al. 2007. Proinflammatory stimuli induce IKKalpha-mediated phosphorylation of PIAS1 to restrict inflammation and immunity. Cell 129: 903-914.
    • (2007) Cell , vol.129 , pp. 903-914
    • Liu, B.1    Yang, Y.2    Chernishof, V.3    Loo, R.R.4    Jang, H.5    Tahk, S.6    Yang, R.7    Mink, S.8    Shultz, D.9    Bellone, C.J.10
  • 31
    • 0141815764 scopus 로고    scopus 로고
    • TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation
    • Saitoh, T., M. Nakayama, H. Nakano, H. Yagita, N. Yamamoto, and S. Yamaoka. 2003. TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation. J. Biol. Chem. 278: 36005-36012.
    • (2003) J. Biol. Chem. , vol.278 , pp. 36005-36012
    • Saitoh, T.1    Nakayama, M.2    Nakano, H.3    Yagita, H.4    Yamamoto, N.5    Yamaoka, S.6
  • 32
    • 24744469009 scopus 로고    scopus 로고
    • Interferon induces NF-kappa B-inducing kinase/tumor necrosis factor receptor-associated factor-dependent NF-kappa B activation to promote cell survival
    • Yang, C. H., A. Murti, and L. M. Pfeffer. 2005. Interferon induces NF-kappa B-inducing kinase/tumor necrosis factor receptor-associated factor-dependent NF-kappa B activation to promote cell survival. J. Biol. Chem. 280: 31530-31536.
    • (2005) J. Biol. Chem. , vol.280 , pp. 31530-31536
    • Yang, C.H.1    Murti, A.2    Pfeffer, L.M.3
  • 33
    • 0033537767 scopus 로고    scopus 로고
    • Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase
    • Hu, Y., V. Baud, M. Delhase, P. Zhang, T. Deerinck, M. Ellisman, R. Johnson, and M. Karin. 1999. Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase. Science 284: 316-320.
    • (1999) Science , vol.284 , pp. 316-320
    • Hu, Y.1    Baud, V.2    Delhase, M.3    Zhang, P.4    Deerinck, T.5    Ellisman, M.6    Johnson, R.7    Karin, M.8
  • 36
    • 0035809983 scopus 로고    scopus 로고
    • IKKalpha controls formation of the epidermis independently of NF-kappaB
    • Hu, Y., V. Baud, T. Oga, K. I. Kim, K. Yoshida, and M. Karin. 2001. IKKalpha controls formation of the epidermis independently of NF-kappaB. Nature 410: 710-714.
    • (2001) Nature , vol.410 , pp. 710-714
    • Hu, Y.1    Baud, V.2    Oga, T.3    Kim, K.I.4    Yoshida, K.5    Karin, M.6
  • 37
    • 1942484963 scopus 로고    scopus 로고
    • IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis
    • Sil, A. K., S. Maeda, Y. Sano, D. R. Roop, and M. Karin. 2004. IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis. Nature 428: 660-664.
    • (2004) Nature , vol.428 , pp. 660-664
    • Sil, A.K.1    Maeda, S.2    Sano, Y.3    Roop, D.R.4    Karin, M.5
  • 38
    • 40649097065 scopus 로고    scopus 로고
    • IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation
    • Descargues, P., A. K. Sil, Y. Sano, O. Korchynskyi, G. Han, P. Owens, X.-J. Wang, and M. Karin. 2008. IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation. Proc. Natl. Acad. Sci. USA 105: 2487-2492.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 2487-2492
    • Descargues, P.1    Sil, A.K.2    Sano, Y.3    Korchynskyi, O.4    Han, G.5    Owens, P.6    Wang, X.-J.7    Karin, M.8
  • 40
    • 0037444638 scopus 로고    scopus 로고
    • A noninvasive genetic/pharmacologic strategy for visualizing cell morphology and clonal relationships in the mouse
    • Badea, T. C., Y. Wang, and J. Nathans. 2003. A noninvasive genetic/pharmacologic strategy for visualizing cell morphology and clonal relationships in the mouse. J. Neurosci. 23: 2314-2322.
    • (2003) J. Neurosci. , vol.23 , pp. 2314-2322
    • Badea, T.C.1    Wang, Y.2    Nathans, J.3
  • 44
    • 0033177995 scopus 로고    scopus 로고
    • Conditional gene targeting in macrophages and granulocytes using LysMcre mice
    • Clausen, B. E., C. Burkhardt, W. Reith, R. Renkawitz, and I. Förster. 1999. Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 8: 265-277.
    • (1999) Transgenic Res. , vol.8 , pp. 265-277
    • Clausen, B.E.1    Burkhardt, C.2    Reith, W.3    Renkawitz, R.4    Förster, I.5
  • 46
    • 20244362085 scopus 로고    scopus 로고
    • Gene expression profiling in conjunction with physiological rescues of IKKalpha-null cells with wild type or mutant IKKalpha reveals distinct classes of IKKalpha/NF-kappaB-dependent genes
    • Massa, P. E., X. Li, A. Hanidu, J. Siamas, M. Pariali, J. Pareja, A. G. Savitt, K. M. Catron, J. Li, and K. B. Marcu. 2005. Gene expression profiling in conjunction with physiological rescues of IKKalpha-null cells with wild type or mutant IKKalpha reveals distinct classes of IKKalpha/NF-kappaB-dependent genes. J. Biol. Chem. 280: 14057-14069.
    • (2005) J. Biol. Chem. , vol.280 , pp. 14057-14069
    • Massa, P.E.1    Li, X.2    Hanidu, A.3    Siamas, J.4    Pariali, M.5    Pareja, J.6    Savitt, A.G.7    Catron, K.M.8    Li, J.9    Marcu, K.B.10
  • 47
    • 58149171655 scopus 로고    scopus 로고
    • Sustained NF-kappaB activation produces a short-term cell proliferation block in conjunction with repressing effectors of cell cycle progression controlled by E2F or FoxM1
    • Penzo, M., P. E. Massa, E. Olivotto, F. Bianchi, R. M. Borzi, A. Hanidu, X. Li, J. Li, and K. B. Marcu. 2009. Sustained NF-kappaB activation produces a short-term cell proliferation block in conjunction with repressing effectors of cell cycle progression controlled by E2F or FoxM1. J. Cell. Physiol. 218: 215-227.
    • (2009) J. Cell. Physiol. , vol.218 , pp. 215-227
    • Penzo, M.1    Massa, P.E.2    Olivotto, E.3    Bianchi, F.4    Borzi, R.M.5    Hanidu, A.6    Li, X.7    Li, J.8    Marcu, K.B.9
  • 49
    • 0015582757 scopus 로고
    • Leukocyte locomotion and chemotaxis. New methods for evaluation, and demonstration of a cell-derived chemotactic factor
    • Zigmond, S. H., and J. G. Hirsch. 1973. Leukocyte locomotion and chemotaxis. New methods for evaluation, and demonstration of a cell-derived chemotactic factor. J. Exp. Med. 137: 387-410.
    • (1973) J. Exp. Med. , vol.137 , pp. 387-410
    • Zigmond, S.H.1    Hirsch, J.G.2
  • 53
    • 0027272534 scopus 로고
    • Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family
    • Fleming, T. J., M. L. Fleming, and T. R. Malek. 1993. Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family. J. Immunol. 151: 2399-2408.
    • (1993) J. Immunol. , vol.151 , pp. 2399-2408
    • Fleming, T.J.1    Fleming, M.L.2    Malek, T.R.3
  • 54
    • 0032555894 scopus 로고    scopus 로고
    • Urokinase receptor (CD87) regulates leukocyte recruitment via beta 2 integrins in vivo
    • May, A. E., S. M. Kanse, L. R. Lund, R. H. Gisler, B. A. Imhof, and K. T. Preissner. 1998. Urokinase receptor (CD87) regulates leukocyte recruitment via beta 2 integrins in vivo. J. Exp. Med. 188: 1029-1037.
    • (1998) J. Exp. Med. , vol.188 , pp. 1029-1037
    • May, A.E.1    Kanse, S.M.2    Lund, L.R.3    Gisler, R.H.4    Imhof, B.A.5    Preissner, K.T.6
  • 55
    • 34548780292 scopus 로고    scopus 로고
    • Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces
    • Woolf, E., I. Grigorova, A. Sagiv, V. Grabovsky, S. W. Feigelson, Z. Shulman, T. Hartmann, M. Sixt, J. G. Cyster, and R. Alon. 2007. Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces. Nat. Immunol. 8: 1076-1085.
    • (2007) Nat. Immunol. , vol.8 , pp. 1076-1085
    • Woolf, E.1    Grigorova, I.2    Sagiv, A.3    Grabovsky, V.4    Feigelson, S.W.5    Shulman, Z.6    Hartmann, T.7    Sixt, M.8    Cyster, J.G.9    Alon, R.10
  • 58
    • 0030910830 scopus 로고    scopus 로고
    • Characterization and functional analysis of the promoter of RAGE, the receptor for advanced glycation end products
    • Li, J., and A. M. Schmidt. 1997. Characterization and functional analysis of the promoter of RAGE, the receptor for advanced glycation end products. J. Biol. Chem. 272: 16498-16506.
    • (1997) J. Biol. Chem. , vol.272 , pp. 16498-16506
    • Li, J.1    Schmidt, A.M.2
  • 59
    • 67649344400 scopus 로고    scopus 로고
    • Alternative splicing of the murine receptor for advanced glycation end-products (RAGE) gene
    • Kalea, A. Z., N. Reiniger, H. Yang, M. Arriero, A. M. Schmidt, and B. I. Hudson. 2009. Alternative splicing of the murine receptor for advanced glycation end-products (RAGE) gene. FASEB J. 23: 1766-1774.
    • (2009) FASEB J. , vol.23 , pp. 1766-1774
    • Kalea, A.Z.1    Reiniger, N.2    Yang, H.3    Arriero, M.4    Schmidt, A.M.5    Hudson, B.I.6
  • 60
    • 54049108485 scopus 로고    scopus 로고
    • A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)
    • Raucci, A., S. Cugusi, A. Antonelli, S. M. Barabino, L. Monti, A. Bierhaus, K. Reiss, P. Saftig, and M. E. Bianchi. 2008. A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10). FASEB J. 22: 3716-3727.
    • (2008) FASEB J. , vol.22 , pp. 3716-3727
    • Raucci, A.1    Cugusi, S.2    Antonelli, A.3    Barabino, S.M.4    Monti, L.5    Bierhaus, A.6    Reiss, K.7    Saftig, P.8    Bianchi, M.E.9
  • 62
    • 15444372287 scopus 로고    scopus 로고
    • Essential role of IkappaB kinase alpha in the constitutive processing of NF-kappaB2 p100
    • Qing, G., and G. Xiao. 2005. Essential role of IkappaB kinase alpha in the constitutive processing of NF-kappaB2 p100. J. Biol. Chem. 280: 9765-9768.
    • (2005) J. Biol. Chem. , vol.280 , pp. 9765-9768
    • Qing, G.1    Xiao, G.2
  • 66
    • 0041355495 scopus 로고    scopus 로고
    • A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts
    • Kishore, N., C. Sommers, S. Mathialagan, J. Guzova, M. Yao, S. Hauser, K. Huynh, S. Bonar, C. Mielke, L. Albee, et al. 2003. A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts. J. Biol. Chem. 278: 32861-32871.
    • (2003) J. Biol. Chem. , vol.278 , pp. 32861-32871
    • Kishore, N.1    Sommers, C.2    Mathialagan, S.3    Guzova, J.4    Yao, M.5    Hauser, S.6    Huynh, K.7    Bonar, S.8    Mielke, C.9    Albee, L.10
  • 68
    • 32444445050 scopus 로고    scopus 로고
    • Promotion of cell adherence and spreading: A novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type I cells
    • Demling, N., C. Ehrhardt, M. Kasper, M. Laue, L. Knels, and E. P. Rieber. 2006. Promotion of cell adherence and spreading: a novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type I cells. Cell Tissue Res. 323: 475-488.
    • (2006) Cell Tissue Res. , vol.323 , pp. 475-488
    • Demling, N.1    Ehrhardt, C.2    Kasper, M.3    Laue, M.4    Knels, L.5    Rieber, E.P.6
  • 69
    • 77954176954 scopus 로고    scopus 로고
    • HMGB1 enhances the proinflammatory activity of lipopolysaccharide by promoting the phosphorylation of MAPK p38 through receptor for advanced glycation end products
    • Qin, Y.-H., S.-M. Dai, G.-S. Tang, J. Zhang, D. Ren, Z.-W. Wang, and Q. Shen. 2009. HMGB1 enhances the proinflammatory activity of lipopolysaccharide by promoting the phosphorylation of MAPK p38 through receptor for advanced glycation end products. J. Immunol. 183: 6244-6250.
    • (2009) J. Immunol. , vol.183 , pp. 6244-6250
    • Qin, Y.-H.1    Dai, S.-M.2    Tang, G.-S.3    Zhang, J.4    Ren, D.5    Wang, Z.-W.6    Shen, Q.7
  • 70
    • 58149122909 scopus 로고    scopus 로고
    • Internalization of the receptor for advanced glycation end products (RAGE) is required to mediate intracellular responses
    • Sevillano, N., M. D. Girón, M. Salido, A. M. Vargas, J. Vilches, and R. Salto. 2009. Internalization of the receptor for advanced glycation end products (RAGE) is required to mediate intracellular responses. J Biochem 145: 21-30.
    • (2009) J Biochem , vol.145 , pp. 21-30
    • Sevillano, N.1    Girón, M.D.2    Salido, M.3    Vargas, A.M.4    Vilches, J.5    Salto, R.6
  • 71
    • 33646364816 scopus 로고    scopus 로고
    • The amphoterin (HMGB1)/receptor for advanced glycation end products (RAGE) pair modulates myoblast proliferation, apoptosis, adhesiveness, migration, and invasiveness. Functional inactivation of RAGE in L6 myoblasts results in tumor formation in vivo
    • Riuzzi, F., G. Sorci, and R. Donato. 2006. The amphoterin (HMGB1)/receptor for advanced glycation end products (RAGE) pair modulates myoblast proliferation, apoptosis, adhesiveness, migration, and invasiveness. Functional inactivation of RAGE in L6 myoblasts results in tumor formation in vivo. J. Biol. Chem. 281: 8242-8253.
    • (2006) J. Biol. Chem. , vol.281 , pp. 8242-8253
    • Riuzzi, F.1    Sorci, G.2    Donato, R.3
  • 73
  • 74
    • 70149092553 scopus 로고    scopus 로고
    • Requirement of HMGB1 for stromal cell-derived factor-1/CXCL12-dependent migration of macrophages and dendritic cells
    • Campana, L., L. Bosurgi, M. E. Bianchi, A. A. Manfredi, and P. Rovere-Querini. 2009. Requirement of HMGB1 for stromal cell-derived factor-1/CXCL12-dependent migration of macrophages and dendritic cells. J. Leukoc. Biol. 86: 609-615.
    • (2009) J. Leukoc. Biol. , vol.86 , pp. 609-615
    • Campana, L.1    Bosurgi, L.2    Bianchi, M.E.3    Manfredi, A.A.4    Rovere-Querini, P.5
  • 75
    • 33845893860 scopus 로고    scopus 로고
    • Pivotal advance: Analysis of proinflammatory activity of highly purified eukaryotic recombinant HMGB1 (amphoterin)
    • Rouhiainen, A., S. Tumova, L. Valmu, N. Kalkkinen, and H. Rauvala. 2007. Pivotal advance: analysis of proinflammatory activity of highly purified eukaryotic recombinant HMGB1 (amphoterin). J. Leukoc. Biol. 81: 49-58.
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 49-58
    • Rouhiainen, A.1    Tumova, S.2    Valmu, L.3    Kalkkinen, N.4    Rauvala, H.5
  • 78
    • 44449162626 scopus 로고    scopus 로고
    • High mobility group box 1 protein binding to lipopolysaccharide facilitates transfer of lipopolysaccharide to CD14 and enhances lipopolysaccharide-mediated TNF-alpha production in human monocytes
    • Youn, J. H., Y. J. Oh, E. S. Kim, J. E. Choi, and J.-S. Shin. 2008. High mobility group box 1 protein binding to lipopolysaccharide facilitates transfer of lipopolysaccharide to CD14 and enhances lipopolysaccharide-mediated TNF-alpha production in human monocytes. J. Immunol. 180: 5067-5074.
    • (2008) J. Immunol. , vol.180 , pp. 5067-5074
    • Youn, J.H.1    Oh, Y.J.2    Kim, E.S.3    Choi, J.E.4    Shin, J.-S.5
  • 79
    • 42149192003 scopus 로고    scopus 로고
    • HMGB1 develops enhanced proinflammatory activity by binding to cytokines
    • Sha, Y., J. Zmijewski, Z. Xu, and E. Abraham. 2008. HMGB1 develops enhanced proinflammatory activity by binding to cytokines. J. Immunol. 180: 2531-2537.
    • (2008) J. Immunol. , vol.180 , pp. 2531-2537
    • Sha, Y.1    Zmijewski, J.2    Xu, Z.3    Abraham, E.4


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