Spinal and peripheral analgesic effects of the CB2 cannabinoid receptor agonist AM1241 in two models of bone cancer-induced pain

British Journal of Pharmacology

Volumn 160, Issue 3, 2010, Pages 561-573

  Curto Reyes, V ^a   Llames, S ^b   Hidalgo, A ^a   Menendez L ^a   Baamonde, A ^a  

^a UNIVERSIDAD DE OVIEDO   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

Author keywords

Allodynia; AM1241; B16 F10 cells; Bone cancer induced pain; Hyperalgesia; Mice; NCTC 2472 cells

Indexed keywords

3 (2 IODO 5 NITROBENZOYL) 1 (1 METHYL 2 PIPERIDINYLMETHYL)INDOLE; 5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; 1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; ANALGESIC AGENT; BORNANE DERIVATIVE; CANNABINOID; CANNABINOID 2 RECEPTOR; NALOXONE; PIPERIDINE DERIVATIVE; PYRAZOLE DERIVATIVE;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE CANCER; CANCER PAIN; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFICACY; DRUG SAFETY; GENE ACTIVATION; HUMAN; HUMAN CELL; HYPERALGESIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; BONE NEOPLASMS; C3H MOUSE; C57BL MOUSE; COMPLICATION; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; DRUG INTERACTION; METABOLISM; OSTEOSARCOMA; PAIN; PAIN MEASUREMENT; SPINAL CORD; SPINAL GANGLION; TUMOR CELL LINE;

ANALGESICS; ANIMALS; BONE NEOPLASMS; BORNANES; CANNABINOIDS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GANGLIA, SPINAL; HUMANS; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; NALOXONE; OSTEOSARCOMA; PAIN; PAIN MEASUREMENT; PIPERIDINES; PYRAZOLES; RECEPTOR, CANNABINOID, CB2; SPINAL CORD;

EID: 77952663261     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00629.x     Document Type: Article

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