IL-4 directs both CD4 and CD8 T cells to produce Th2 cytokines in vitro, but only CD4 T cells produce these cytokines in response to alum-precipitated protein in vivo

Molecular Immunology

Volumn 47, Issue 10, 2010, Pages 1914-1922

  Serre, Karine ^a   Mohr, Elodie ^a   Gaspal, Fabrina ^a   Lane, Peter J L ^a   Bird, Roger ^a   Cunningham, Adam F ^a   MacLennan, Ian C M ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Aluminum adjuvant; CD4 T cells; CD8 T cells; Cytokine receptors; Cytokines; Interleukin 4; Ovalbumin; T helper 2 cells; Vaccination

Indexed keywords

ALUMINUM POTASSIUM SULFATE; CD134 ANTIGEN; CHEMOKINE RECEPTOR CXCR5; CYTOKINE; IMMUNOGLOBULIN G1; INTERLEUKIN 13; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 5; PROGRAMMED DEATH 1 RECEPTOR; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR C MAF; TRANSCRIPTION FACTOR GATA 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL POLARITY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; HELPER CELL; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; TH2 CELL; UPREGULATION;

ALUM COMPOUNDS; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL SEPARATION; CYTOKINES; FLOW CYTOMETRY; IMMUNOLOGIC FACTORS; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OVALBUMIN; PEPTIDE FRAGMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TH2 CELLS;

EID: 77952548422     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.03.010     Document Type: Article

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