Mycophenolic acid inhibits the phosphorylation of NF-κB and JNKs and causes a decrease in IL-8 release in H2O2-treated human renal proximal tubular cells

Chemico-Biological Interactions

Volumn 185, Issue 3, 2010, Pages 253-262

  Andreucci, Michele ^a   Faga, Teresa ^a   Lucisano, Gaetano ^a   Uccello, Francesco ^b   Pisani, Antonio ^b   Memoli, Bruno ^b   Sabbatini, Massimo ^b   Fuiano, Giorgio ^a   Michael, Ashour ^a,b  

^a UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Inflammation; Kinase; Mycophenolic acid; Renal

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY ISCHEMIA; KIDNEY PROXIMAL TUBULE; NONHUMAN; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; CYTOLOGY; DRUG ANTAGONISM; METABOLISM; PHOSPHORYLATION;

RATTUS;

CELL LINE; HUMANS; HYDROGEN PEROXIDE; INTERLEUKIN-8; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KIDNEY TUBULES, PROXIMAL; MYCOPHENOLIC ACID; NF-KAPPA B; PHOSPHORYLATION;

EID: 77952294468     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.03.019     Document Type: Article

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