Zn2+-induced IL-8 expression involves AP-1, JNK, and ERK activities in human airway epithelial cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 290, Issue 5, 2006, Pages

  Kim, Yu Mee ^a   Reed, William ^b   Wu, Weidong ^b   Bromberg, Philip A ^b   Graves, Lee M ^b   Samet, James M ^c,d  

^a University of North Carolina at Chapel Hill   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^d U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Activating protein 1; c Jun NH2 terminal kinase; Extracellular signal regulated kinase; Interleukin 8; Metal; Mitogen activated protein kinase phosphatase; Particulate matter; Zinc

Indexed keywords

ACTIVATING PROTEIN 1; ACTIVATING TRANSCRIPTION FACTOR 1; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN TYROSINE PHOSPHATASE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ZINC; TRANSCRIPTION FACTOR AP 1;

ARTICLE; BRONCHUS MUCOSA; CELL LINE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; ENZYME ACTIVITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; ONCOGENE C FOS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; LUNG; METABOLISM; PHYSIOLOGY; RESPIRATORY TRACT MUCOSA;

CELL LINE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-8; LUNG; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; RESPIRATORY MUCOSA; RNA, MESSENGER; TRANSCRIPTION FACTOR AP-1; ZINC;

EID: 33646681855     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00479.2005     Document Type: Article

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