Radiocontrast media cause dephosphorylation of Akt and downstream signaling targets in human renal proximal tubular cells

Biochemical Pharmacology

Volumn 72, Issue 10, 2006, Pages 1334-1342

  Andreucci, Michele ^a   Fuiano, Giorgio ^a   Presta, Pierangela ^a   Esposito, Pasquale ^b   Faga, Teresa ^a   Bisesti, Vincenzo ^b   Procino, Alfredo ^b   Altieri, Vincenzo ^b   Tozzo, Carmela ^c   Memoli, Bruno ^b   Michael, Ashour ^a,b  

^a UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Cell survival; Kidney; Kinase; Nephrotoxicity; Signaling; Tubular cells

Indexed keywords

CONTRAST MEDIUM; DIATRIZOATE; IOMEPROL; IOPROMIDE; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE; PROTEIN KINASE B; SERINE; THREONINE; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DOWNSTREAM PROCESSING; DRUG BLOOD LEVEL; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INCUBATION TIME; INTRACELLULAR SPACE; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN FAMILY; SIGNAL TRANSDUCTION; TARGET VARIABLE;

CELL LINE; CELL SURVIVAL; CONTRAST MEDIA; DOWN-REGULATION; EPITHELIAL CELLS; HUMANS; KIDNEY TUBULES, PROXIMAL; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 33750201137     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2006.08.008     Document Type: Article

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