Mycophenolate mofetil inhibits rat and human mesangial cell proliferation by guanosine depletion

Nephrology Dialysis Transplantation

Volumn 14, Issue 1, 1999, Pages 58-63

  Hauser, Ingeborg A ^a,d   Renders, Lutz ^b   Radeke, Heinfried H ^c   Sterzel, R Bernd ^b   Goppelt Struebe, Margarete ^b  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Glomerulonephritis; Immunosuppressive therapy; Inosine monophosphate dehydrogenase; Mesangial cell proliferation; Mycophenolate mofetil; Purine synthesis

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CALCIUM ION; DNA; FURA 2 ACETOXYMETHYL ESTER; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE; LYSOPHOSPHATIDIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PLATELET DERIVED GROWTH FACTOR; TRYPAN BLUE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL NUCLEUS; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DNA SYNTHESIS; FETAL CALF SERUM; HUMAN; HUMAN CELL; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROLIFERATIVE GLOMERULONEPHRITIS; RAT;

ANIMALS; APOPTOSIS; CALCIUM; CELL DIVISION; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; CYTOSOL; GLOMERULAR MESANGIUM; GUANOSINE; HUMANS; ILIAC ARTERY; IMMUNOSUPPRESSIVE AGENTS; IMP DEHYDROGENASE; LYSOPHOSPHOLIPIDS; MUSCLE, SMOOTH, VASCULAR; MYCOPHENOLIC ACID; NECROSIS; PLATELET-DERIVED GROWTH FACTOR; RATS;

EID: 0032894546     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/14.1.58     Document Type: Article

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