Promoter knock-in mutations reveal a role of Mcl-1 in thymocyte-positive selection and tissue or cell lineage-specific regulation of Mcl-1 expression

Journal of Immunology

Volumn 182, Issue 5, 2009, Pages 2959-2968

  Yang, Chia Yu ^a   Lin, Nai Hui ^b   Lee, Jan Mou ^a   Huang, Ching Yu ^d   Min, Hsiang Ju ^e   Yen, Jeffrey Jong Young ^a,c   Liao, Nan Shih ^a,b,e   Yang Yen, Hsin Fang ^a,b,e  

^a ACADEMIA SINICA   (Taiwan)

^b INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

^c INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^d NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PROTEIN MCL 1; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; PROTEIN BCL 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL LINEAGE; CELL MATURATION; CELL SELECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CRE 2 GENE; FEMALE; FLOW CYTOMETRY; GENE; GENE EXPRESSION REGULATION; GENE LOCUS; GENE MUTATION; GENE OVEREXPRESSION; HEART; HOMOZYGOSITY; LIVER; LUNG; LYMPHOCYTOPENIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SIE GENE; SPLEEN; THYMOCYTE; THYMUS; ANIMAL; ANTIBODY SPECIFICITY; BIOSYNTHESIS; C57BL MOUSE; CELL DIFFERENTIATION; CYTOLOGY; GENE TARGETING; GENETICS; IMMUNOLOGY; METABOLISM; METHODOLOGY; MOUSE MUTANT; MUTATION; PATHOLOGY; PHYSIOLOGY; T LYMPHOCYTE SUBPOPULATION; TRANSGENIC MOUSE;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; FEMALE; GENE EXPRESSION REGULATION; GENE KNOCK-IN TECHNIQUES; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MUTATION; ORGAN SPECIFICITY; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-BCL-2; T-LYMPHOCYTE SUBSETS; THYMUS GLAND;

EID: 64849107994     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803550     Document Type: Article

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