Effect of danshen extract on the activity of CYP3A4 in healthy volunteers

British Journal of Clinical Pharmacology

Volumn 69, Issue 6, 2010, Pages 656-662

  Qiu, Furong ^a   Wang, Guangji ^b   Zhang, Rong ^b   Sun, Jianguo ^b   Jiang, Jian ^a   Ma, Yueming ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

CYP3A4; Danshen extract; Drug interaction; Midazolam

Indexed keywords

1 HYDROXYLMIDAZOLAM; CYTOCHROME P450 3A4; DRUG METABOLITE; MIDAZOLAM; SALVIA MILTIORRHIZA EXTRACT; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG BLOOD LEVEL; DRUG METABOLISM; ENZYME ACTIVITY; HUMAN; IN VIVO STUDY; MALE; NORMAL HUMAN; OPEN STUDY; PRIORITY JOURNAL; SALVIA MILTIORRHIZA; SINGLE DRUG DOSE;

ADMINISTRATION, ORAL; ADULT; AREA UNDER CURVE; CHINA; CYTOCHROME P-450 CYP3A; DRUGS, CHINESE HERBAL; HUMANS; HYPNOTICS AND SEDATIVES; MALE; MIDAZOLAM; YOUNG ADULT;

EID: 77952039173     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2010.03624.x     Document Type: Article

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