HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage

Oncogene

Volumn 24, Issue 35, 2005, Pages 5431-5442

  Di Stefano, Valeria ^a   Soddu, Silvia ^a   Sacchi, Ada ^a   D'Orazi, Gabriella ^a,b  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

Author keywords

Acetylation; Chromatin immunoprecipitation; DNA damage; HIPK2; p53; PCAF

Indexed keywords

CISPLATIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; DNA; HISTONE ACETYLTRANSFERASE PCAF; HOMEODOMAIN INTERACTING PROTEIN KINASE 2; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; RNA; ANTINEOPLASTIC AGENT; CARRIER PROTEIN; CDKN1A PROTEIN, HUMAN; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; HIPK2 PROTEIN, HUMAN; HISTONE ACETYLTRANSFERASE; PCAF PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

ACETYLATION; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DNA STRAND BREAKAGE; HUMAN; HUMAN CELL; MITOSIS INHIBITION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS INHIBITION; PROTEIN SYNTHESIS REGULATION; RNA INTERFERENCE; TRANSACTIVATION; TUMOR SUPPRESSOR GENE; APOPTOSIS; DNA DAMAGE; DOSE RESPONSE; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETICS; IMMUNOPRECIPITATION; METABOLISM; NICK END LABELING; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

ACETYLATION; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CISPLATIN; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTONE ACETYLTRANSFERASES; HUMANS; IMMUNOPRECIPITATION; IN SITU NICK-END LABELING; PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 24644494726     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1208717     Document Type: Article

References (45)

1. Appella E and Anderson CW. (2000). Pathol. Biol. (Paris), 48, 227-245.
2. Appella E and Anderson CW. (2001). Eur. J. Biochem., 268, 2764-2772.
3. Ashcroft M, Taya Y and Vousden KH. (2000). Mol. Cell. Biol., 20, 3224-3233.
4. Banin S, Moyal L, Shieh S, Taya Y, Anderson CW, Chessa L, Smorodinsky NI, Prives C, Reiss Y, Shiloh Y and Ziv Y. (1998). Science, 281, 1674-1677.
5. Barlev NA, Liu L, Chehab NH, Mansfield K, Harris KG, Halazonetis TD and Berger SL. (2001). Mol Cell, 8, 1243-1254.
6. Bulavin DV, Saito S, Hollander MC, Sakaguchi K, Anderson CW, Appella E and Fornace AJ. (1999). EMBO J., 18, 6845-6854.
7. Canman CE, Lim DS, Cimprich KA, Taya Y, Tamai K, Sakaguchi K, Appella E, Kastan MB and Siliciano JD. (1998). Science, 281, 1677-1679.
8. Chehab NH, Malikzay A, Appel M and Halazonetis TD. (2000). Genes Dev., 14, 278-288.
9. Costanzo A, Merlo P, Pediconi N, Fulco M, Sartorelli V, Cole PA, Fontemaggi G, Fanciulli M, Schiltz L, Blandino G, Balsano C and Levrero M. (2002). Mol. Cell, 9, 175-186.
10. Di Stefano V, Rinaldo C, Sacchi A, Soddu S and D'Orazi G. (2004a). Exp. Cell Res., 293, 311-320.
11. Di Stefano V, Blandino G, Sacchi A, Soddu S and D'Orazi G. (2004b). Oncogene, 23, 5185-5192.
12. D'Orazi G, Cecchinelli B, Bruno T, Manni I, Higashimoto Y, Saito S, Gostissa M, Coen S, Marchetti A, Del Sal G, Piaggio G, Fanciulli M and Soddu S. (2002). Nat. Cell Biol., 4, 11-19.
13. el Deiry W, Tokino T, Velculescu VE, Levy DB, Parson R, Trent JM, Lin D, Mercer WE, Kinzler KW and Vogelstein B. (1993). Cell, 75, 817-825.
14. Espinosa JM and Emerson BM. (2001). Cell, 8, 57-69.
15. Friedlander P, Haupt Y, Prives C and Oren M. (1996). Mol. Cell. Biol., 16, 4961-4971.
16. Giaccia AJ and Kastan LB. (1998). Genes Dev., 12, 2973-2983.
17. Gottlieb T and Oren M. (1996). Biochim. Biophys. Acta, 1287, 77-102.
18. Gu W and Roeder RG. (1997). Cell, 90, 595-606.
19. Hirao A, Kong YY, Matsuoka S, Wakeham A, Ruland J, Yoshida H, Liu D, Elledge SJ and Mak TW. (2000). Science, 287, 1824-1827.
20. Hofmann TG, Moller A, Sirma H, Zentgraf H, Taya Y, Droge W, Will H and Schmitz ML. (2002). Nat. Cell Biol., 4, 1-10.
21. Ko LJ, Shieh SY, Chen X, Jayaraman L, Tamai K, Taya Y, Prives C and Pan ZQ. (1997). Mol. Cell. Biol., 17, 7220-7229.
22. Lees-Miller SP, Sakaguchi K, Ullrich SJ, Appella E and Andersen CW. (1992). Mol. Cell. Biol., 12, 5041-5049.
23. Liu L, Scolnick DM, Trievel RC, Zhang HB, Marmorstein R, Halazonetis TD and Berger SL. (1999). Mol. Cell. Biol., 19, 1202-1209.
24. Luo J, Li M, Tang Y, Laszkowska M, Roeder RG and Gu W. (2003). Proc. Natl. Acad. Sci. USA, 101, 2259-2264.
25. Luo J, Su F, Chen D, Shiloh A and Gu W. (2000). Nature, 408, 377-381.
26. Manni I, Mazzaro G, Gurtner A, Mantovani R, Haugwitz U, Krause K, Engeland K, Sacchi A, Soddu S and Piaggio G. (2001). J. Biol. Chem., 276, 5570-5576.
27. Martinez-Balbas MA, Bauer UM, Nielsen SJ, Brehm A and Kouzarides T. (2000). EMBO J., 19, 662-671.
28. Miyashita T and Reed JC. (1995). Cell, 80, 293-299.
29. Moller A, Sirma H, Hofmann TG, Rueffer S, Klimczak E, Droge W and Schmitz ML. (2003). Cancer Res., 63, 4310-4314.
30. Munshi N, Agalioti T, Lomvardas S, Merita M, Chen G and Thanos D. (2001). Science, 293, 1133-1136.
31. Oda K, Arakawa H, Tanaka T, Matsuda K, Tanikawa C, Mori T, Nishimori H, Tamai K, Tokino T, Nakamura Y and Taya Y. (2000a). Cell, 102, 849-862.
32. Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, Tokino T, Taniguchi T and Tanaka N. (2000b). Science, 288, 1053-1058.
33. Pediconi N, Ianari A, Costanzo A, Belloni L, Gallo R, Cimino L, Porcellini A, Screpanti I, Balsano C, Alesse E, Gulino A and Levrero M. (2003). Nat. Cell Biol., 5, 552-558.
34. Prives C and Hall PA. (1999). J. Pathol., 187, 112-126.
35. Prives C and Manley JL. (2001). Cell, 107, 815-818.
36. Ryan KM and Vousden KH. (1998). Mol. Cell. Biol., 18, 3692-3698.
37. Saito S, Yamaguchi H, Higashimoto Y, Chao C, Xu Y, Roenace AJ, Appella E and Anderson CW. (2003). J. Biol. Chem., 39, 37536-37544.
38. Sakaguchi K, Herrera JE, Saito S, Miki T, Bustin M, Vassilev A, Anderson CW and Appella E. (1998). Genes Dev., 12, 2831-2841.
39. Saller E, Tom E, Brunori M, Otter M, Estreicher A, Mack DH and Iggo R. (1999). EMBO J., 18, 4424-4437.
40. Sartorelli V, Puri PL, Hamamori Y, Ogryzko V, Chung G, Nakatani Y, Wang JY and Kedes L. (1999). Mol. Cell, 4, 725-734.
41. Shieh SY, Ahn J, Tamai K, Taya Y and Prives C. (2000). Genes Dev., 14, 289-300.
42. Shieh S-Y, Ikeda M, Taya Y and Prives C. (1997). Cell, 9, 325-334.
43. Tibbetts RS, Brumbaugh KM, Williams JM, Sarkaria JN, Cliby WA, Shieh SY, Taya Y, Prives C and Abraham RT. (1999). Genes Dev., 13, 152-157.
44. Vogt Sionov R and Haupt Y. (1999). Oncogene, 18, 6145-6157.
45. Wang Y, Blandino G, Oren M and Givol D. (1998). Oncogene, 177, 1923-1930.