Overexpression of human NOX1 complex induces genome instability in mammalian cells

Free Radical Biology and Medicine

Volumn 44, Issue 3, 2008, Pages 332-342

  Chiera, Federica ^a   Meccia, Ettore ^a   Degan, Paolo ^b   Aquilina, Gabriele ^a   Pietraforte, Donatella ^a   Minetti, Maurizio ^a   Lambeth, David ^c   Bignami, Margherita ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

8 OxoGua; DNA repair; Free radicals; Genetic instability; hNOX1; Reactive oxygen species

Indexed keywords

3 NITROTYROSINE; 8 HYDROXYGUANINE; DNA; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; PROTEIN MSH2; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; EMBRYO CELL; FIBROBLAST; GENE EXPRESSION; GENE OVEREXPRESSION; GENOMIC INSTABILITY; HELA CELL; HUMAN; HUMAN CELL; MAMMAL CELL; MISMATCH REPAIR; MUTATIONAL ANALYSIS; NITRATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEADY STATE;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; DNA DAMAGE; GENOMIC INSTABILITY; GUANINE; HELA CELLS; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MICE; MUTAGENESIS; MUTS HOMOLOG 2 PROTEIN; NADPH OXIDASE; OXIDATIVE STRESS;

MAMMALIA;

EID: 38149054921     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2007.09.018     Document Type: Article

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