Narcolepsy: Autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss

Brain

Volumn 133, Issue 5, 2010, Pages 1300-1311

  Fontana, Adriano ^a   Gast, Heidemarie ^b   Reith, Walter ^c   Recher, Mike ^a   Birchler, Thomas ^a   Bassetti, Claudio L ^d  

^a INSTITUTE OF EXPERIMENTAL IMMUNOLOGY   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Cytokines; Molecular mimicry; Sleep; T cell receptor

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; HLA DQB1 ANTIGEN; HLA DR2 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OREXIN; QUINOLINIC ACID; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR 2;

AUTOIMMUNITY; CATAPLEXY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DEATH; CELL KILLING; CELL LOSS; DNA POLYMORPHISM; EFFECTOR CELL; HUMAN; HYPOTHALAMUS; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MICROGLIA; NARCOLEPSY; NERVE CELL; NERVOUS SYSTEM INFLAMMATION; NEUROTOXICITY; ONSET AGE; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; STREPTOCOCCUS INFECTION; T LYMPHOCYTE ACTIVATION; UPREGULATION;

ANIMALS; AUTOIMMUNITY; CATAPLEXY; CELL DEATH; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; INFECTION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOCYTE ACTIVATION; NARCOLEPSY; NEURONS; NEUROPEPTIDES; T-LYMPHOCYTES;

EID: 77951891860     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awq086     Document Type: Review

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